AT Innsbruck Oroboros

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Oroboros Instruments

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AT Innsbruck Oroboros

Oroboros O2k-Network

O2k-Network
O2k-Network Lab
Oroboros

Oroboros Instruments Corp


High-resolution respirometry

O2k – Mitochondrial and cell research

Address instruments@oroboros.at

Schöpfstraße 18, A-6020

City Innsbruck
State/Prov
Country Austria
Weblink Oroboros Instruments, Bioblast
Contact Oroboros, Gnaiger Erich
Team Bastos Sant'Anna Silva Ana Carolina, Beno Marija, Cardoso Luiza, Cocco Paolo, Colomer Yvette, Di Marcello Marco, Doerrier Carolina, Erhart Verena, Gallee Leon, Garcia e Souza Luiz Felipe, Garipi Enis, Gnaiger Andrea, Gnaiger Carolina, Gradl Lukas, Gradl Philipp, Haider Markus, Harrison David K, Huete-Ortega Maria, Iglesias-Gonzalez Javier, Komlodi Timea, Kranewitter Sabine, Krumschnabel Gerhard, Laner Verena, Leman Geraldine, Liebscher Gudrun, Meszaros Andras, Nirschl Lisa, Passrugger Manuela, Plangger Mario, Radis Christina, Volani Chiara, Weber Anja, Zhang Feiyuan
Team previous Bader Helga, Burtscher Johannes, Capek Ondrej, Davidikova Sarka, Eigentler Andrea, Fasching Mario, Gasser Juliane, Gellerich Frank N, Hansl Marielle, Heidler Juliana, Hiller Elisabeth, Hoppel Florian, Horvath Gergo, Kandolf Georg, Kuznetsov Andrey V, Lamberti Giorgia, Lassnig Barbara, Lemieux Helene, Martic Ines, Mendez Gabriela, Neves Pedro, Perez Valencia Juan Alberto, Pesta Dominik, Pranger Florian, Renner-Sattler Kathrin, Rieger Gunde, Scandurra Francesca M, Schmarl Johannes, Schoepf Bernd, Sigl Reinhard, Simonovik Biljana, Steinlechner-Maran Rosmarie, Subarsky Patrick, Sumbalova Zuzana, Wiethuechter Anita, Wohlfarter Yvonne
Status The Power-O2k 1992-
Oroboros Events Bioblast 2012, O2k-Workshops
Topics High-resolution respirometry, Oroboros O2k, Gentle Science


O2k-Publications

 PublishedReference
MiPNet19.14 SOP Hamilton microsyringes2019-07-02
O2k-Protocols
SOP for manual O2k-titrations with Hamilton microsyringes.
MiPNet22.16 DatLab 7 Innovations: DL-Protocols2019-07-01
O2k-Protocols
DatLab 7.4 Innovations: DL-Protocols
MiPNet23.12 DL-Protocols help2019-07-01
O2k-Protocols
DatLab Protocols: Help DatLab 7.
MiPNet18.06 Amplex-Yeast2019-06-24
O2k-Protocols
O2k-FluoRespirometry: Amplex UltraRed using freeze-dried baker’s yeast.
MiPNet20.13 Safranin mt-membranepotential2019-06-24
O2k-Protocols
O2k-FluoRespirometry: HRR and simultaneous determination of mt-membrane potential with safranin or TMRM.
MiPNet20.14 AmplexRed H2O2-production2019-06-24
O2k-Protocols
O2k-FluoRespirometry: HRR and simultaneous determination of H2O2 production with Amplex UltraRed.
MiPNet18.05 Amplex-Mouse-heart2019-06-24
O2k-Protocols
O2k-Fluorometry: HRR and H2O2 production in mouse cardiac tissue homogenate.
MiPNet24.04 IOC140 Amsterdam NL2019-06-23
O2k-Network
Amsterdam NL, 2019 Jun 23 Pre-conference Oroboros O2k-Workshop on high-resolution respirometry (HRR), IOC140.
MiPNet19.03 O2k-cleaning and ISS2019-06-13
O2k-Protocols
O2k-Chamber cleaning SOP and Integrated Suction System (ISS).
MiPNet19.18B POS-service2019-05-15
O2k-Manual
Service of the polarographic oxygen sensor OroboPOS.
MiPNet24.03 IOC138 Xiamen CN2019-04-12
O2k-Network
Xiamen CN, 2019 Apr 12. Post-conference Oroboros O2k-Workshop on high-resolution respirometry (HRR), IOC138.
MiPNet12.23 FiberRespiration2019-01-10
O2k-Protocols contents
Mitochondrial respiration in permeabilized fibers: Needle biopsies from horse skeletal muscle.
Gnaiger 2019 MitoPathways2019
O2k-Protocols
Gnaiger E (2019) Mitochondrial pathways and respiratory control. An introduction to OXPHOS analysis. 5th ed. Mitochondr Physiol Network 24.05. Oroboros MiPNet Publications, Innsbruck:96 pp.
Schoepf 2019 MitoFit Preprint Arch2019Schöpf B, Weissensteiner H, Schäfer G, Fazzini F, Charoentong P, Naschberger A, Rupp B, Fendt L, Bukur V, Eichelbrönner I, Sorn P, Sahin U, Kronenberg F, Gnaiger E, Klocker H (2019) OXPHOS remodeling in high-grade prostate cancer involves mtDNA mutations and a prognostic gene expression signature. MitoFit Preprint Arch doi:10.26124/mitofit:190003.
Lemieux 2019 bioRxiv2019Lemieux H, Subarsky P, Doblander C, Wurm M, Troppmair J, Gnaiger E (2019) Mitochondrial respiratory function as an early biomarker of apoptosis induced by growth factor removal. bioRxiv doi: https://doi.org/10.1101/151480 .
Di Marcello 2019 MitoFit Preprint Arch EA2019Di Marcello M, Iglesias-Gonzalez J, Meszaros A, Haider M, Gnaiger E, Huete-Ortega M (2019) Partitioning between cytochrome c oxidase and alternative oxidase studied by oxygen kinetics of dark respiration in Chlamydomonas reinhardtii: a microalgae model organism. MitoFit Preprint Arch doi:10.26124/mitofit:ea19.MiPSchool.0005.v3.
Doerrier 2019 MitoFit Preprint Arch EA2019Doerrier C, Gama-Perez P, Distefano G, Pesta D, Soendergaard SD, Chroeis KM, Gonzalez-Franquesa A, Goodpaster BH, Coen P, Larsen S, Gnaiger E, Garcia-Roves PM (2019) Inter-laboratory harmonization of respiratory protocols in permeabilized human muscle fibers. MitoFit Preprint Arch doi:10.26124/mitofit:ea19.MiPSchool.0009.
MiPNet23.09 IOC136 Melbourne AU2018-11-27
O2k-Network
Melbourne AU, 2018 Nov 27-28 Oroboros O2k-Workshop on high-resolution respirometry (HRR), IOC136.
MiPNet12.01 Suppl T-issue2018-11-18
O2k-Protocols contents
MitoPathways at the Q-junction: mouse skeletal muscle fibers.
MiPNet23.15 O2k-pH ISE-Module2018-09-08
O2k-Manual
Measurement of proton flux with the O2k-pH ISE-Module.
MiPNet23.04 IOC133 Innsbruck AT2018-09-05
OROBOROS-solo.png
Innsbruck AT, 2018 Sep 05-07. MitoFit Coaching Days - Basic IOC 133.
MiPNet23.07 IOC132 Budapest HU2018-08-24
O2k-Network
Budapest HU, 2018 Aug 24-25 Oroboros satellite O2k-Workshop on high-resolution respirometry (HRR), IOC.
MiPNet14.06 Instrumental O2 background2018-08-07
O2k-Protocols
O2k Quality Control 2: Instrumental oxygen background correction and accuracy of oxygen flux.
MiPNet23.13 IOC131 Kuala Lumpur MY2018-07-17
O2k-Network
Kuala Lumpur MY, 2018 Jul 17 Oroboros satellite O2k-Workshop on high-resolution respirometry (HRR), IOC131.
MiPNet21.16 DatLab 7 Innovations2018-07-12
About Oroboros
DatLab 7: innovations.
MiPNet21.06 SUIT RP2018-06-25
O2k-Protocols
SUIT reference protocol for OXPHOS analysis by high-resolution respirometry.
MiPNet23.10 IOC129 Lausanne CH2018-06-04
O2k-Network
Lausanne CH, 2018 Jun 04-05 Oroboros O2k-Workshop on high-resolution respirometry (HRR), IOC129.
MiPNet23.03 IOC128 Cambridge UK2018-05-07
O2k-Network
Cambridge UK, 2018 May 7-8. Oroboros satellite O2k-Workshop on high-resolution respirometry IOC128.
MiPNet18.10 O2k specifications2018-05-02
Oroboros
O2k-FluoRespirometer: specifications for respirometry and comprehensive OXPHOS analysis.
MiPNet21.17 BloodCellsIsolation2018-04-09
O2k-Protocols
O2k-Protocols: Isolation of blood cells for HRR.
MiPNet23.02 IOC127 Szeged HU2018-03-27
O2k-Network
Szeged HU, 2018 Mar 27. Oroboros satellite O2k-Workshop on hypoxia IOC127.
MiPNet15.03 O2k-MultiSensor-ISE2018-01-25
O2k-Manual
O2k-MultiSensor system with ion selective electrodes (ISE).
MiPNet06.03 POS-calibration-SOP2018-01-07
O2k-Protocols
O2k Quality Control 1: Polarographic oxygen sensors and accuracy of calibration.
Burtscher 2018 Front Mol Neurosci2018Burtscher J, Bean C, Zangrandi L, Kmiec I, Agostinho A, Scorrano L, Gnaiger E, Schwarzer C (2018) Proenkephalin derived peptides are involved in the modulation of mitochondrial respiratory control during epileptogenesis. Front Mol Neurosci doi:10.3389/fnmol.2018.00351.
Sumbalova 2018 Recent Advances Mitochondr Med Coenzyme Q102018Sumbalová Z, Garcia-Souza LF, Cizmarova B, Volani C, Gnaiger E (2018) Analysis of mitochondrial function in human blood cells. In: Recent advances in mitochondrial medicine and Coenzyme Q10. Gvozdjáková A, Cornelissen G, Singh RB eds, Nova Sciences:255-68.
Oemer 2018 Proc Nat Acad Sci U S A2018Oemer G, Lackner L, Muigg K, Krumschnabel G, Watschinger K, Sailer S, Lindner H, Gnaiger E, Wortmann SB, Werner ER, Zschocke J, Keller MA (2018) The molecular structural diversity of mitochondrial cardiolipins. Proc Nat Acad Sci U S A 115:4158-63.
Weber 2018 Int J Mol Sci2018Weber A, Klocker H, Oberacher H, Gnaiger E, Neuwirt H, Sampson N, Eder IE (2018) Succinate accumulation is associated with a shift of mitochondrial respiratory control and HIF-1α upregulation in PTEN negative prostate cancer cells. Int J Mol Sci 19:2129.
Haschka 2018 Mov Disord2018Haschka D, Volani C, Stefani A, Tymoszuk P, Mitterling T, Holzknecht E, Heidbreder A, Coassin S, Sumbalova Z, Seifert M, Dichtl S, Theurl I, Gnaiger E, Kronenberg F, Frauscher B, Högl B, Weiss G (2018) Association of mitochondrial iron deficiency and dysfunction with idiopathic restless legs syndrome. Mov Disord 34:114-23.
Chicco 2018 J Biol Chem2018Chicco AJ, Le CH, Gnaiger E, Dreyer HC, Muyskens JB, D'Alessandro A, Nemkov T, Hocker AD, Prenni JE, Wolfe LM, Sindt NM, Lovering AT, Subudhi AW, Roach RC (2018) Adaptive remodeling of skeletal muscle energy metabolism in high-altitude hypoxia: Lessons from AltitudeOmics. J Biol Chem 293:6659-71.
Komlodi 2018 Methods Mol Biol2018Komlodi T, Sobotka O, Krumschnabel G, Bezuidenhout N, Hiller E, Doerrier C, Gnaiger E (2018) Comparison of mitochondrial incubation media for measurement of respiration and hydrogen peroxide production. Methods Mol Biol 1782:137-55.
Doerrier 2018 Methods Mol Biol2018Doerrier C, Garcia-Souza LF, Krumschnabel G, Wohlfarter Y, Mészáros AT, Gnaiger E (2018) High-Resolution FluoRespirometry and OXPHOS protocols for human cells, permeabilized fibers from small biopsies of muscle, and isolated mitochondria. Methods Mol Biol 1782:31-70.
Gatterer 2018 J Sports Sci Med2018Gatterer H, Menz V, Salazar-Martinez E, Sumbalova Z, Garcia-Souza LF, Cizmarova B, Gnaiger E, Burtscher M (2018) Exercise performance, muscle oxygen extraction and blood cell mitochondrial respiration after repeated-sprint and sprint interval training in hypoxia: a pilot study. J Sports Sci Med 17:339-347.
MiPNet22.15 IOC125 Prague CZ2017-11-20
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Prague CZ, 2017 Nov 20. Oroboros O2k-Workshop on DatLab7 IOC125. O2k-Network Lab »CZ Prague Houstek J
MiPNet22.08 IOC123 Xian CN2017-09-11
O2k-Network
Xian CN, 2017 Sep 11 Oroboros O2k-Workshop on high-resolution respirometry (HRR), IOC123.
MitoFit Open Seminar 2017-07-142017-07-14
MitoFit
Innsbruck AT, 2017 Jul 14. MitoFit Open Seminar on immune cell bioenergetics.
Investigating the role of mitochondria in healthy and psychopathological aging.
MiPNet22.04 IOC120 Barcelona ES2017-03-20
O2k-Network
Barcelona ES, 2017 Mar 20. O2k-Workshop on high-resolution respirometry (HRR) IOC120. »ES Barcelona Zorzano A
MiPNet22.03 IOC119 Innsbruck AT2017-02-27
OROBOROS-solo.png
Innsbruck AT, 2017 Feb 28-Mar 03. MitoFit Coaching Days - Basic IOC119.
MiPNet22.02 IOC118 Hyderabad IN2017-02-07
O2k-Network
Hyderabad IN, 2017 Feb 07-08 Oroboros Pre-conference O2k-Workshop on high-resolution respirometry (HRR), IOC118.  »IN Hyderabad Thangaraj K.
MiPNet15.09. Yeast: HRR Reference Assay2017-02-05
O2k-Protocols
A mitochondrial reference assay for high-resolution respirometry using freeze-dried Baker’s yeast.
Enhancing physiological understanding of exercise and obesity: designing personalised intervention strategies 2017 Stellenbosch ZA2017-01-30Stellenbosch ZA, 2017 Jan 30-Feb 02. Enhancing physiological understanding of exercise and obesity: designing personalised intervention strategies.
Lemieux 2017 Sci Rep2017Lemieux H, Blier PU, Gnaiger E (2017) Remodeling pathway control of mitochondrial respiratory capacity by temperature in mouse heart: electron flow through the Q-junction in permeabilized fibers. Sci Rep 7:2840, DOI:10.1038/s41598-017-02789-8.
Lopez 2017 PLOS ONE2017López A, Ortiz F, Doerrier C, Venegas C, Fernández-Ortiz M, Aranda P, Díaz-Casado ME, Fernández-Gil B, Barriocanal-Casado E, Escames G, López L, Acuña-Castroviejo D (2017) Mitochondrial impairment and melatonin protection in parkinsonian mice do not depend of inducible or neuronal nitric oxide synthases. PLOS ONE 12:e0183090.
Bernardinelli 2017 PLoS One2017Bernardinelli E, Costa R, Scantamburlo G, To J, Morabito R, Nofziger C, Doerrier C, Krumschnabel G, Paulmichl M, Dossena S (2017) Mis-targeting of the mitochondrial protein LIPT2 leads to apoptotic cell death. PLoS One 12(6):e0179591.
Permer 2017 Bachelor Thesis2017Permer M (2017) Respirometrische Charakterisierung kryopräservierter HEK 239T Zellen. Bachelor Thesis 1-56.
Miller 2017 PLOS ONE2017Miller B, Hamilton K, Boushel R, Williamson K, Laner V, Gnaiger E, Davis M (2017) Mitochondrial respiration in highly aerobic canines in the non-raced state and after a 1600-km sled dog race. PLOS ONE 12:e0174874.
Horscroft 2017 Proc Natl Acad Sci U S A2017Horscroft JA, Kotwica AO, Laner V, West JA, Hennis PJ, Levett DZH, Howard DJ, Fernandez BO, Burgess SL, Ament Z, Gilbert-Kawai ET, Vercueil A, Landis BD, Mitchell K, Mythen MG, Branco C, Johnson RS, Feelisch M, Montgomery HE, Griffin JL, Grocott MPW, Gnaiger E, Martin DS, Murray AJ (2017) Metabolic basis to Sherpa altitude adaptation. Proc Natl Acad Sci U S A 114:6382–7.
Volani 2017 Metallomics2017Volani C, Doerrier C, Demetz E, Haschka D, Paglia G, Lavdas AA, Gnaiger E, Weiss G (2017) Dietary iron loading negatively affects liver mitochondrial function. Metallomics 9:1634-44.
MiPNet21.13 Comparison mt-preparations2016-10-18
O2k-Protocols
O2k-Protocols: Mitochondrial preparations for HRR.
MiPNet19.18C DatLab 6: Guide2016-08-24
O2k-Manual
DatLab-guide through the menus.
MiPNet19.18D O2k-Series G and DatLab 6: Calibration2016-08-24
O2k-Protocols
O2k-calibration by DatLab 6.
MiPNet08.09 CellRespiration2016-08-11
O2k-Procedures contents
High-resolution respirometry and coupling control protocol with living cells: ROUTINE, LEAK, ET-pathway, ROX.
MiPNet12.10 TIP2k-manual2016-08-10
O2k-Manual
Titration-Injection microPump. TIP2k user manual.
MiPNet17.05 O2k-Fluo LED2-Module2016-08-09
O2k-Manual
O2k-Fluo LED2-Module.
MiPNet21.09 IOC113 Havana CU2016-08-08
O2k-Network
Havana CU, 2016 Aug 08-09. Oroboros O2k-Workshop on high-resolution respirometry (HRR) and O2k-Fluorometry, IOC113. O2k-Network Lab » CU Havana Pardo Andreu GL
MiPNet19.18 O2k-Series G Core manual2016-08-08
O2k-Manual
O2k-Core manual contents.
MiPNet19.18E O2 flux analysis - DatLab 62016-08-08
O2k-Manual
Oxygen flux analysis: DatLab real-time.
MiPNet10.04 CellRespiration2016-08-08
O2k-Protocols
An experiment with high-resolution respirometry: coupling control in cell respiration.
MiPNet19.18A O2k-Series G: Start2016-08-08
O2k-Manual
Oxygraph-2k: start high-resolution respirometry.
MiPNet20.04 O2k-checklist2016-08-05
O2k-Protocols
O2k-checklist: get started with an O2k-experiment.
MiPNet21.07 MitoFit DatLab PT2016-07-20
O2k-Protocols
MitoFit DatLab proficiency test.
MiPNet21.02 IOC111 Seattle WA US2016-06-13
O2k-Network
Seattle WA US, 2016 Jun 13-14. Oroboros O2k-Workshop on high-resolution respirometry (HRR) and O2k-Fluorometry, IOC111. O2k-Network Lab »US WA Seattle Marcinek DJ
MiPNet15.05 NO-manual2016-04-21
O2k-Manual
O2k-MultiSensor system with amperometric sensors: NO, H2S, H2O2.
MiPNet21.04 IOC110 Melbourne AU2016-04-12
O2k-Network
Melbourne AU, 2016 Apr 12-13. Oroboros O2k-Workshop on high-resolution respirometry (HRR) and O2k-Fluorometry, IOC110. O2k-Network Lab »AU Melbourne Stepto NK
MiPNet14.05 TPP-mtMembranePotential2016-04-01
O2k-Protocols contents
TPP+ and mt-membrane potential.
MiPNet21.05 IOC108 Singapore SG2016-03-06
O2k-Network
Singapore SG, 2016 Mar 06-07. Oroboros O2k-Workshop on high-resolution respirometry (HRR) and O2k-Fluorometry, IOC108.
Schoepf 2016 FEBS J2016Schöpf B, Schäfer G, Weber A, Talasz H, Eder IE, Klocker H, Gnaiger E (2016) Oxidative phosphorylation and mitochondrial function differ between human prostate tissue and cultured cells. FEBS J 283:2181-96.
Pesta 2016 FASEB J2016Pesta DH, Tsirigotis DN, Befroy DE, Caballero D, Jurczak MJ, Rahimi Y, Cline GW, Dufour S, Birkenfeld AL, Rothman DL, Carpenter TO, Insogna K, Petersen KF, Bergwitz C, Shulman GI (2016) Hypophosphatemia promotes lower rates of muscle ATP synthesis. FASEB J 30:3378-87.
MiPNet21.12 Comparison mt respiration media2016
O2k-Protocols
O2k-MultiSensor: Mitochondrial respiration media for HRR and simultaneous O2k-Fluorometry.
MiPNet21.14 Reference sample HRR2016
O2k-Protocols
Development of a reference sample for HRR.
Moll 2016 bioRxiv2016Moll CWI, Lindtner RA, Vogel GF, Brunner M, Gutleben K, Blauth M, Krumschnabel G, Ebner HL (2016) Bone marrow mesenchymal stem cells from osteoporotic patients do not show altered mitochondrial energetics or ultrastructure. bioRxiv doi.org/10.1101/046300.
MiPNet20.10 IOC106 Schroecken2015-10-06
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Schroecken AT, 2015 Oct 06-11. Oroboros O2k-Workshop on HRR and O2k-Fluorometry, IOC106.
MiPNet20.16 IOC105 Riga2015-08-27
O2k-Network
Riga LV, 2015 Aug 27. Oroboros O2k-Workshop on high-resolution respirometry (HRR) and O2k-Fluorometry - innovabalt, IOC105.
MiPNet20.05 IOC104 Greenville2015-08-09
O2k-Network
Greenville NC US, 2015 Aug 09-10. Oroboros O2k-Workshop on HRR and O2k-Fluorometry, IOC104.
MiPNet20.12 IOC103 Manaus2015-07-06
O2k-Network
Manaus BR, 2015 Jul 06-10. To the heart of the Amazon. O2k-Workshop on HRR and O2k-Fluorometry, IOC103.
MiPNet17.15 PBI-Shredder Mouse-heart-brain-liver2015-06-22
O2k-Protocols
Tissue homogenates for diagnosis of mitochondrial respiratory function: Mouse heart, brain and liver.
MiPNet17.03 Shredder vs Fibers2015-06-18
O2k-Protocols
Mitochondrial respiration in permeabilized fibers versus homogenate from fish liver and heart. An application study with the PBI-Shredder.
MiPNet17.16 O2k-Spectrophotometry2015-06-16
O2k-Protocols
O2k-Spectrophotometry - A MitoCom Project.
MiPNet19.17 O2k Series G2015-06-15
Oroboros-Info
O2k Series G: innovations
MiPNet19.19 DatLab 62015-06-15
About Oroboros
DatLab 6: innovations.
MiPNet20.11 IOC102 Wuhan CN2015-05-25
O2k-Network
Wuhan CN, 2015 May 25-26. Oroboros O2k-Workshop on HRR and O2k-Fluorometry, IOC102. Oroboros representative in China: »:CN Shanghai Zenda.
MiPNet06.06 Chemical O2 background2015-04-27
O2k-Protocols
Oxygraph assay of cytochrome c oxidase activity: chemical background correction.
MiPNet20.03 IOC101 London2015-04-21
O2k-Network
London UK, 2015 Apr 21-23. Oroboros O2k-Workshop on HRR and O2k-Fluorometry, IOC101.
MiPNet20.02 IOC99 Cape Town2015-03-23
O2k-Network
Cape Town ZA, 2015 Mar 23-24. Oroboros O2k-Workshop on HRR and O2k-Fluorometry, IOC99. - Satellite to 7th MiPschool Cape Town 2015.
Dueregger 2015 PLoS One2015Dueregger A, Schöpf B, Eder T, Höfer J, Gnaiger E, Aufinger A, Kenner L, Perktold B, Ramoner R, Klocker H, Eder IE (2015) Differential utilization of dietary fatty acids in benign and malignant cells of the prostate. PLoS One 10(8):e0135704.
Ofer 2015 Mol Endocrinol2015Ofer P, Heidegger I, Eder IE, Schöpf B, Neuwirt H, Geley S, Klocker H, Massoner P (2015) Both IGF1R and INSR knockdown exert anti-tumorigenic effects in prostate cancer in vitro and in vivo. Mol Endocrinol 29:1694-707.
Makrecka-Kuka 2015 Biomolecules2015
O2k-Protocols contents
Makrecka-Kuka M, Krumschnabel G, Gnaiger E (2015) High-resolution respirometry for simultaneous measurement of oxygen and hydrogen peroxide fluxes in permeabilized cells, tissue homogenate and isolated mitochondria. Biomolecules 5:1319-38.
Burtscher 2015 Mitochondrion2015Burtscher J, Zangrandi L, Schwarzer C, Gnaiger E (2015) Differences in mitochondrial function in homogenated samples from healthy and epileptic specific brain tissues revealed by high-resolution respirometry. Mitochondrion 25:104-12.
Krumschnabel 2015 Methods Mol Biol2015
O2k-Protocols contents
Krumschnabel G, Fontana-Ayoub M, Sumbalova Z, Heidler J, Gauper K, Fasching M, Gnaiger E (2015) Simultaneous high-resolution measurement of mitochondrial respiration and hydrogen peroxide production. Methods Mol Biol 1264:245-61.
Blatzer 2015 Antioxid Redox Signal2015Blatzer M, Jukic E, Posch W, Schöpf B, Binder U, Steger M, Blum G, Hackl H, Gnaiger E, Lass-Flörl C, Wilflingseder D (2015) Amphotericin B resistance in Aspergillus terreus is overpowered by co-application of pro-oxidants. Antioxid Redox Signal 23:1424-38.
Gnaiger 2015 Scand J Med Sci Sports2015Gnaiger E, Boushel R, Søndergaard H, Munch-Andersen T, Damsgaard R, Hagen C, Díez-Sánchez C, Ara I, Wright-Paradis C, Schrauwen P, Hesselink M, Calbet JAL, Christiansen M, Helge JW, Saltin B (2015) Mitochondrial coupling and capacity of oxidative phosphorylation in skeletal muscle of Inuit and caucasians in the arctic winter. Scand J Med Sci Sports 25 (Suppl 4):126–34.
Boushel 2015 Scand J Med Sci Sports2015Boushel R, Gnaiger E, Larsen FJ, Helge JW, Gonzalez-Alonso J, Ara I, Munch-Andersen T, van Hall G, Søndergaard H, Saltin B, Calbet JAL (2015) Maintained peak leg and pulmonary VO2 despite substantial reduction in muscle mitochondrial capacity. Scand J Med Sci Sports 25 (Suppl 4):135–43.
Harrison 2015 J Appl Physiol2015Harrison DK, Fasching M, Fontana-Ayoub M, Gnaiger E (2015) Cytochrome redox states and respiratory control in mouse and beef heart mitochondria at steady-state levels of hypoxia. J Appl Physiol 119:1210-8.
Doerrier 2015 Thesis2015Doerrier C (2015) Estudio bioenergetica mitochondrial en la sepsis experimental y efecto protector de la Melatonina. Doctoral Thesis p154.
MiPNet19.16 IOC982014-11-17
O2k-Network
Taipei TW, 2014 Nov 17-20. Oroboros O2k-Workshop on HRR and O2k-Fluorometry, IOC98.
MiPNet19.15 IOC972014-09-25
O2k-Network
Lausanne CH, 2014 Sep. 25-26 Oroboros O2k-Workshop on HRR and O2k-Fluorometry, IOC97.
MiPNet19.09 IOC94 Shanghai CN2014-06-27
O2k-Network
Shanghai CN, 2014 Jun 27-Jul 02. Oroboros O2k-Workshop on HRR and O2k-Fluorometry, IOC94. Oroboros representative in China: »CN Shanghai Zenda.
MiPNet19.06 IOC91 Philadelphia US2014-06-02
O2k-Network
Philadelphia US, 2014 Jun 02-03. Oroboros O2k-Workshop on HRR and O2k-Fluorometry, IOC91. O2k-Network Lab »US PA Philadelphia Wallace DC.
MiPNet19.05 IOC90 Bolzano IT2014-05-27
OROBOROS-solo.png
Bolzano IT, 2014 May 27. Applied Workshop - High-resolution respirometry and mitochondrial function under hypoxia: overview, demo experiment and discussion. IOC90 at ISMM2014.
MiPNet19.04 IOC89 La Jolla US2014-05-01
O2k-Network
La Jolla US, 2014 May 01-02. Oroboros O2k-Workshop on HRR and O2k-Fluorometry, IOC89. O2k-Network Lab »US CA La Jolla Felding-Habermann B
MiPNet18.16 IOC87 Spitsbergen2014-03-24
O2k-Network
Spitsbergen NO, 2014 Mar 24-27. Oroboros O2k-Workshop on HRR and O2k-Fluorometry: Spitsbergen - Enjoy the Cold, IOC87. MiPNet Lab »NO Trondheim Rognmo O.
MiPNet12.11 MitoRespiration2014-02-20
O2k-Protocols
Flux control ratios in isolated mitochondria. OXPHOS capacity and respiratory control.
MiPNet18.15 IOC862014-01-31
O2k-Network
Mumbay IN, 2014 Jan 31. Oroboros O2k-Workshop on HRR and O2k-Fluorometry, IOC86. »IN Mumbai Kolthur-Seetharam U
MiPNet18.14 IOC852014-01-28
Oroboros Instruments
Mahabaleshwar IN, 2014 Jan 28-30. OROBOROS O2k-Workshop on HRR and O2k-Fluorometry, IOC85 at 38th Mahabaleshwar Seminar. MiPNet Lab »IN Mumbai Kolthur-Seetharam U.
MiPNet18.13 IOC84 Alaska2014-01-04
O2k-Network
Big Lake, Alaska US, 2014 Jan 04-07. Oroboros O2k-Workshop on HRR and Racing dogs at Iditarod, IOC84.  »US OK Stillwater Davis MS
Larsen 2014 Anal Biochem2014Larsen S, Kraunsøe R, Gram M, Gnaiger E, Helge JW, Dela F (2014) The best approach: homogenization or manual permeabilization of human skeletal muscle fibers for respirometry? Anal Biochem 446:64-8.
Gnaiger 2014 MitoPathways2014
O2k-Protocols
Gnaiger E (2014) Mitochondrial pathways and respiratory control. An introduction to OXPHOS analysis. 4th ed. Mitochondr Physiol Network 19.12. Oroboros MiPNet Publications, Innsbruck:80 pp.
Boushel 2014 Acta Physiol (Oxf)2014Boushel RC, Ara I, Gnaiger E, Helge JW, Gonzalez-Alonzo J, Munck-Andersen T, Sondergaard H, Damsgaard R, van Hall G, Saltin B, Calbet JA (2014) Low intensity training increases peak arm VO2 by enhancing both convective and diffusive O2 delivery. Acta Physiol (Oxf) 211:122-34.
Chicco 2014 J Exp Biol2014Chicco AJ, Le CH, Schlater AE, Nguyen AD, Kaye SD, Beals JW, Scalzo RL, Bell C, Gnaiger E, Costa DP, Crocker DE, Kanatous SB (2014) High fatty acid oxidation capacity and phosphorylation control despite elevated leak and reduced respiratory capacity in northern elephant seal muscle mitochondria. J Exp Biol 217:2947-55.
Krumschnabel 2014 Methods Enzymol2014
O2k-Protocols contents
Krumschnabel G, Eigentler A, Fasching M, Gnaiger E (2014) Use of safranin for the assessment of mitochondrial membrane potential by high-resolution respirometry and fluorometry. Methods Enzymol 542:163-81.
Ferko 2014 Physiol Res2014Ferko M, Kancirová I, Jašová M, Čarnická S, Muráriková M, Waczulíková I, Sumbalová Z, Kucharská J, Uličná O, Ravingerová T, Ziegelhöffer A (2014) Remote ischemic preconditioning of the heart: protective responses in functional and biophysical properties of cardiac mitochondria. Physiol Res 63:469-78.
MiPNet18.17 IOC832013-12-18
O2k-Network
Bangalore IN, 2013 Dez 18. Oroboros O2k-Workshop on HRR and O2k-Fluorometry, IOC83.
MiPNet18.11 IOC822013-12-10
O2k-Network
Trondheim NO, 2013 Dec 10-11, Oroboros O2k-Workshop on high-resolution respirometry and O2k-Fluorometry, Oroboros IOC82. Satellite to the 5th Seminar on Exercise in Medicine. Trondheim, Norway, O2k-Network Lab »NO Trondheim Rognmo O.
MiPNet18.19 IOC812013-11-05
O2k-Network
Seoul KR, 2013 Nov 05. Oroboros O2k-Workshop on HRR and O2k-Fluorometry, IOC81.
MiPNet18.18 IOC772013-06-13
Oroboros Instruments
Newport Beach US, 2013 Jun 13. Oroboros O2k-Workshop on HRR and O2k-Fluorometry, IOC77.
MiPNet18.04 IOC762013-05-28
O2k-Network
Prague CZ, 2013 May 28-29. Oroboros O2k-Workshop on high-resolution respirometry (HRR) and O2k-Fluorometry, IOC76. O2k-Network Lab »CZ Prague Kalous M.
MiPNet18.01 IOC732013-01-15
O2k-Network
Kolkata IN, 2013 Jan 15-16. O2k-Workshop on high-resolution respirometry, IOC73. O2k-Network Lab »IN Kolkata Chakrabarti S.
Jacobs 2013 Exp Physiol2013Jacobs R, Boushel RC, Wright-Paradis C, Calbet JA, Robach P, Gnaiger E, Lundby C (2013) Mitochondrial function in human skeletal muscle following high altitude exposure. Exp Physiol 98:245-55.
MiPNet18.08 MiP20132013
MiPsociety
Laner V, Bidaurratzaga E, Gnaiger E, eds (2013) Comparative Mitochondrial Physiology. MiP2013. Mitochondr Physiol Network 18.08:96 pp. ISBN 978-3-9502399-7-3
MiPNet17.20 IOC712012-11-07
O2k-Network
Chongqing CN, 2012 Nov 07. Oroboros O2k-Workshop on high-resolution respirometry (HRR) and O2k-Fluorometry, IOC71.
MiPNet17.10 IOC702012-05-29
O2k-Network
Barcelona ES, 2012 May 29-30. Oroboros O2k-Workshop on High-Resolution Respirometry (HRR), IOC70.  »ES Barcelona Garcia-Roves PM.
MiPNet17.07 IOC672012-04-02
O2k-Network
Sidney AU, 2012 Apr 02-04. Oroboros O2k-Workshop on high-resolution respirometry, IOC67. »AU Sydney Stocker R.
Pesta 2012 Methods Mol Biol2012
O2k-Protocols
Pesta D, Gnaiger E (2012) High-resolution respirometry. OXPHOS protocols for human cells and permeabilized fibers from small biopsies of human muscle. Methods Mol Biol 810:25-58.
Gnaiger 2012 Mitochondr Physiol Network Bioblast 20122012
Oroboros
Gnaiger E, Meissner B, Laner V, eds (2012) Bioblast 2012: Mitochondrial Competence. Mitochondr Physiol Network 17.12. Oroboros MiPNet Publications, Innsbruck:96 pp. ISBN 978-3-9502399-5-9
Iyer 2012 Hum Gene Ther2012Iyer S, Bergquist K, Young K, Gnaiger E, Rao RR, Bennett JP Jr (2012) Mitochondrial gene therapy improves respiration, biogenesis and transcription in G11778A Leber’s hereditary optic neuropathy and T8993G Leigh’s syndrome cells. Hum Gene Ther 23:647-57.
MiPNet08.12 IOC222011-12-11
O2k-Protocols
NO effect on mitochondrial oxygen kinetics at low oxygen. O2k workshop Report.
MiPNet15.08 TPP electrode2011-12-11
O2k-Protocols
Ion selective electrode for TPP+ and high-resolution respirometry.
MiPNet12.17 BovineHeartMito2011-12-11
O2k-Protocols contents
Mitochondrial respiration with frozen bovine heart mitochondria: diagnostic tests.
MiPNet16.02 IOC642011-12-08
O2k-Network
Hyderabad IN, 2011 Dec 08. Oroboros O2k-Workshop on high-resolution respirometry (HRR) - Satellite to 1st SMRM, IOC64. »IN Hyderabad Thangaraj K.
MiPNet16.05 IOC632011-08-26
O2k-Network
Beijing CN, 2011 Aug 26-27. Oroboros O2k-Workshop on high-resolution respirometry (HRR) and O2k-Fluorometry, IOC63.
MiPNet16.04 IOC622011-07-11
Oroboros Instruments
Innsbruck AT, 2011 Jul 11-13. Oroboros O2k-Workshop on high-resolution respirometry (HRR) and O2k-Fluorometry, IOC62.
IOC622011Innsbruck, AT, 2011 Jul 11-13 Introductory O2k-Workshop - MitoCom Tyrol IOC62.
Boushel 2011 Mitochondrion2011Boushel RC, Gnaiger E, Calbet JA, Gonzalez-Alonso J, Wright-Paradis C, Sondergaard H, Ara I, Helge JW, Saltin B (2011) Muscle mitochondrial capacity exceeds maximal oxygen delivery in humans. Mitochondrion 11:303-7.
Pesta 2011 Am J Physiol Regul Integr Comp Physiol2011Pesta D, Hoppel F, Macek C, Messner H, Faulhaber M, Kobel C, Parson W, Burtscher M, Schocke M, Gnaiger E (2011) Similar qualitative and quantitative changes of mitochondrial respiration following strength and endurance training in normoxia and hypoxia in sedentary humans. Am J Physiol Regul Integr Comp Physiol 301:R1078–87.
Lemieux 2011 Int J Biochem Cell Biol2011Lemieux H, Semsroth S, Antretter H, Höfer D, Gnaiger E (2011) Mitochondrial respiratory control and early defects of oxidative phosphorylation in the failing human heart. Int J Biochem Cell Biol 43:1729–38.
MiPNet12.20 O2k-calibration tutorial2010-10-19
O2k-Protocols
O2k: Oxygen calibration and O2k-background tutorial.
MiPNet15.11 IOC582010-08-27
Oroboros Instruments
Debrecen HU, 2010 Aug 27- Sep 02. Oroboros O2k-Workshop on high-resolution respirometry (HRR) and O2k-Fluorometry, IOC58.
MiPNet15.12 IOC57 Druskininkai LT2010-06-10
O2k-Network
Druskininkai LT, 2010 Jun 10- 16. Oroboros O2k-Workshop on high-resolution respirometry (HRR) and O2k-Fluorometry, IOC57.
MiPNet06.05 Specifications2010
Logo OROBOROS INSTRUMENTS.jpg
Gnaiger E (2010) Test experiments on specifications of the Oroboros Oxygraph. Mitochondr Physiol Network 6.5.
Scandurra 2010 Adv Exp Med Biol2010Scandurra FM, Gnaiger E (2010) Cell respiration under hypoxia: facts and artefacts in mitochondrial oxygen kinetics. Adv Exp Med Biol 662:7-25.
Renner-Sattler 2010 Mitochondr Physiol Network MiP20102010
MiPsociety
Renner-Sattler K, Gnaiger E, eds (2010) Mitochondrial physiology. The many functions of the organism in our cells. Mitochondr Physiol Network 15.6:128 pp. ISBN 978-3-9502399-4-2
Sommer 2010 Eur Respir J2010Sommer N, Pak O, Schörner S, Derfuss T, Krug A, Gnaiger E, Ghofrani HA, Schermuly RT, Huckstorf C, Seeger W, Grimminger F, Weissmann N (2010) Mitochondrial cytochrome redox states and respiration in acute pulmonary oxygen sensing. Eur Respir J 36:1056-66.
Kozlov 2010 Inflammation2010Kozlov AV, van Griensven M, Haindl S, Kehrer I, Duvigneau JC, Hartl RT, Ebel T, Jafarmadar M, Calzia E, Gnaiger E, Redl H, Radermacher P, Bahrami Sl (2010) Peritoneal inflammation in pigs is associated with early mitochondrial dysfunction in liver and kidney. Inflammation 33:295-305.
MiPNet14.08 IOC522009-06-21
O2k-Network
Baton Rouge US, 2009 Jun 21. Demo O2k-Workshop, IOC52 at MiPsummer 2009. O2k-Network Lab »US LA Baton Rouge Hand SC.
MiPNet14.02 IOC492009-02-23
O2k-Network
Gainsville US, 2009 Feb 23-25. Oroboros O2k-Workshop on high-resolution respirometry (HRR), IOC49.  »US FL Gainsville Univ Florida.
Gnaiger 2009 Int J Biochem Cell Biol2009Gnaiger E (2009) Capacity of oxidative phosphorylation in human skeletal muscle. New perspectives of mitochondrial physiology. Int J Biochem Cell Biol 41:1837-45.
Gnaiger 2009 Oroboros MiPArt Publications2009Gnaiger E, Agreiter R (2009) Richard Agreiter: Mysterium der seriellen Form. Einmaligkeit – Wiederholbarkeit - Gültigkeit: Bedeutungswandel in Kunst und Wissenschaft. Oroboros MiPArt Publications, Innsbruck, Austria:53pp.
IOC482008-11-09
Oroboros Instruments
Tianjin CN, 2008 Nov 09. Workshop at the 5th Meeting of ASMRM Jointly with Chinese Mit'2008 Tianjin University of Sport, IOC48.
Gnaiger 2008 POS2008
O2k-Protocols contents
Gnaiger E (2008) Polarographic oxygen sensors, the oxygraph and high-resolution respirometry to assess mitochondrial function. In: Mitochondrial Dysfunction in Drug-Induced Toxicity (Dykens JA, Will Y, eds) John Wiley & Sons, Inc, Hoboken, NJ:327-52.
Schneeberger 2008 Shock2008Schneeberger S, Kuznetsov AV, Seiler R, Renz O, Meusburger H, Mark W, Brandacher G, Margreiter R, Gnaiger E (2008) Mitochondrial ischemia-reperfusion injury of the transplanted rat heart: improved protection by preservation versus cardioplegic solutions. Shock 30:365-71.
MiPNet12.04 IOC382007-03-03
O2k-Network
Rome IT, 2007 Mar 03. Oroboros O2k-Workshop on high-resolution respirometry (HRR) and mitochondrial physiology. Oroboros IOC38, »IT Roma Sarti P
MiPNet12.03 IOC372007-02-04
O2k-Network
Seoul KR, 2007 Feb 04. Oroboros O2k-Workshop on high-resolution respirometry (HRR) and mitochondrial physiology. Oroboros IOC37. »KR Seoul Lee HK.
MiPNet09.01 O2k-ParadigmShift2007Gnaiger E, Gradl P (2007) Oxygraph-2k: Paradigm shift and features of high-resolution respirometry. Mitochondr Physiol Network 09.01.
Huetter 2006 Exp Gerontol2006Hütter E, Unterluggauer H, Garedew A, Jansen-Dürr P, Gnaiger E (2006) High-resolution respirometry - a modern tool in aging research. Exp Gerontol 41:103-9.
Garedew 2005 Eur Shock Soc2005Garedew A, Hütter E, Haffner B, Gradl P, Gradl L, Jansen-Dürr P, Gnaiger E (2005) High-resolution respirometry for the study of mitochondrial function in health and disease. The Oroboros O2k. Proc 11th Congress Eur Shock Soc, Vienna, Austria (Redl H, ed) Medimond, Bologna:107-11.
Manzl 2004 J Exp Zool A2004Manzl C, Krumschnabel G, Schwarzbaum PJ, Chabicovsky M, Dallinger R (2004) Intracellular pH regulation in isolated hepatopancreas cells from the Roman snail (Helix pomatia). J Exp Zool A 301:75-84.
Kuznetsov 2004 Am J Physiol Heart Circ Physiol2004Kuznetsov AV, Schneeberger S, Seiler R, Brandacher G, Mark W, Steurer W, Saks V, Usson Y, Margreiter R, Gnaiger E (2004) Mitochondrial defects and heterogeneous cytochrome c release after cardiac cold ischemia and reperfusion. Am J Physiol Heart Circ Physiol 286:H1633–41.
Manzl 2004 Comp Biochem Physiol C Toxicol Pharmacol2004Manzl C, Krumschnabel G, Schwarzbaum PJ, Dallinger R (2004) Acute toxicity of cadmium and copper in hepatopancreas cells from the Roman snail (Helix pomatia). Comp Biochem Physiol C Toxicol Pharmacol 138:45-52.
Krumschnabel 2004 Aquat Toxicol2004Krumschnabel G, Nawaz M (2004) Acute toxicity of hexavalent chromium in isolated teleost hepatocytes. Aquat Toxicol 70:159-167.
Traufeller 2004 Biochim Biophys Acta2004Traufeller K, Gellerich FN, Zierz S (2004) Different sensitivities of CPT I and CPT II for inhibition by L-aminocarnitine in human skeletal muscle. Biochim Biophys Acta 1608:149-54.
Krumschnabel 2003 J Exp Biol2003Krumschnabel G, Gstir R, Manzl C, Prem C, Pafundo D, Schwarzbaum PJ (2003) Metabolic and ionic responses of trout hepatocytes to anisosmotic exposure. J Exp Biol 206:1799-1808.
Renner 2003 Biochim Biophys Acta2003Renner K, Amberger A, Konwalinka G, Gnaiger E (2003) Changes of mitochondrial respiration, mitochondrial content and cell size after induction of apoptosis in leukemia cells. Biochim Biophys Acta 1642:115-23.
Kuznetsov 2003 Anal Biochem2003Kuznetsov AV, Kunz WS, Saks V, Usson Y, Mazat J-P, Letellier T, Gellerich FN, Margreiter R (2003) Cryopreservation of mitochondria and mitochondrial function in cardiac and skeletal muscle fibers. Anal Biochem 319:296-303.
Seppet 2003 Cardiac Remodeling and Failure2003Seppet E, Peet N, Paju K, Ress M, Saks V, Gellerich FN, Chen Y, Trumbeckaite S, Prondzinsky R, Silber R, Werdan K, Zierz S, Seppet EK (2003) Mitochondrial function in failing human myocardium in vitro: atrioventricular differences. In: Cardiac Remodeling and Failure (Singal P, Dixon I, Lorrie A. Kirshenbaum L, Dhalla N eds. Kiuwer Academic Publishers, Boston: 459-470.
Renner 2002 Mol Biol Rep2002Renner K, Kofler R, Gnaiger E (2002) Mitochondrial function in glucocorticoid triggered T-ALL cells with transgenic Bcl-2 expression. Mol Biol Rep 29:97-101.
Gellerich 2002 Biochim Biophys Acta (Vol 1556)2002Gellerich FN, Deschauer M, Chen Y, Müller T, Neudecker S, Zierz S (2002) Mitochondrial respiratory rates and activities of respiratory chain complexes correlate linearly with heteroplasmy of deleted mtDNA without threshold and independently of deletion size. Biochim Biophys Acta 1556:41-52.
Stadlmann 2002 Transplantation2002Stadlmann S, Rieger G, Amberger A, Kuznetsov AV, Margreiter R, Gnaiger E (2002) H2O2-mediated oxidative stress versus cold ischemia-reperfusion: mitochondrial respiratory defects in cultured human endothelial cells. Transplantation 74:1800-3.
Steininger 2002 J Antimicrob Chemother2002Steininger C, Allerberger F, Gnaiger E (2002) Clinical significance of inhibition kinetics in Streptococcus pyogenes in response to penicillin. J Antimicrob Chemother 50:517-23.
Gellerich 2002 Biochim Biophys Acta (Vol 1554)2002Gellerich FN, Laterveer FD, Zierz S, Nicolay K (2002) The quantitation of ADP diffusion gradients across the outer membrane of heart mitochondria in the presence of macromolecules. Biochim Biophys Acta 1554:48-56.
Gnaiger 2002 Biochem Soc Trans2002Gnaiger E, Kuznetsov AV (2002) Mitochondrial respiration at low levels of oxygen and cytochrome c. Biochem Soc Trans 30:242-8.
Opalka 2002 Biochem Pharmacol2002Opalka JR, Gellerich FN, Kling L, Müller-Beckmann B, Zierz S (2002) Effect of the new matrix metalloproteinase inhibitor RO-28-2653 on mitochondrial function. Biochem Pharmacol 63:725-32.
Huetter 2002 Mol Biol Rep2002Hütter E, Renner K, Jansen-Dürr P, Gnaiger E (2002) Biphasic oxygen kinetics of cellular respiration and linear oxygen dependence of antimycin A inhibited oxygen consumption. Mol Biol Rep 29:83-7.
Kuznetsov 2002 Anal Biochem2002Kuznetsov AV, Strobl D, Ruttmann E, Königsrainer A, Margreiter R, Gnaiger E (2002) Evaluation of mitochondrial respiratory function in small biopsies of liver. Anal Biochem 305:186-94.
Krumschnabel 2001 Gen Comp Endocrinol2001Krumschnabel G, Manzl C, Schwarzbaum PJ (2001) Metabolic responses to epinephrine stimulation in goldfish hepatocytes: evidence for the presence of alpha-adrenoceptors. Gen Comp Endocrinol 121:205-213.
Wieser 2001 Biochem J2001Wieser W, Krumschnabel G (2001) Hierarchies of ATP-consuming processes: direct compared with indirect measurements, and comparative aspects. Biochem J 355:389-395.
MiPNet06.01 O2k-Overview2001
Oroboros
Gnaiger E (2001) The Oxygraph for high-resolution respirometry. Mitochondr Physiol Network 06.01.
Krumschnabel 2001 Physiol Biochem Zool2001Krumschnabel G, Manzl C, Schwarzbaum PJ (2001) Importance of glycolysis for the energetics of anoxia-tolerant and anoxia-intolerant teleost hepatocytes. Physiol Biochem Zool 74:413-419.
Braun 2001 Biochim Biophys Acta2001Braun U, Paju K, Eimre M, Seppet E, Orlova E, Kadaja L, Trumbeckaite S, Gellerich FN, Zierz S, Jockusch H, Seppet EK (2001) Lack of dystrophin is associated with altered integration of the mitochondria and ATPases in slow-twitch muscle cells of MDX mice. Biochim Biophys Acta 1505:258-70.
Krumschnabel 2001 J Exp Biol2001Krumschnabel G, Manzl C, Schwarzbaum PJ (2001) Regulation of intracellular pH in anoxia-tolerant and anoxia-intolerant teleost hepatocytes. J Exp Biol 204:3943-3951.
Trumbeckaite 2001 Eur J Biochem2001Trumbeckaite S, Opalka JR, Neuhof C, Zierz S, Gellerich FN (2001) Different sensitivity of rabbit heart and skeletal muscle to endotoxin-induced impairment of mitochondrial function. Eur J Biochem 268:1422-9.
Krumschnabel 2000b J Exp Biol2000bKrumschnabel G, Biasi C, Wieser W (2000b) Action of adenosine on energetics, protein synthesis and K(+) homeostasis in teleost hepatocytes. J Exp Biol 203:2657-2665.
Krumschnabel 2000a J Exp Biol2000aKrumschnabel G, Schwarzbaum PJ, Lisch J, Biasi C, Wieser W (2000a) Oxygen-dependent energetics of anoxia-tolerant and anoxia-intolerant hepatocytes. J Exp Biol 203:951-959.
Gnaiger 2000 Transplant Proc2000Gnaiger E, Kuznetsov AV, Königsrainer A, Margreiter R (2000) Autooxidation of glutathione in organ preservation solutions. Transplant Proc 32:14.
Gnaiger 2000 Transpl Int2000Gnaiger E, Kuznetsov AV, Rieger G, Amberger A, Fuchs A, Stadlmann S, Eberl T, Margreiter R (2000) Mitochondrial defects by intracellular calcium overload versus endothelial cold ischemia/reperfusion injury. Transpl Int 13:555-7.
Gnaiger 2000 Life in the Cold2000
O2k-Protocols contents
Gnaiger E, Kuznetsov AV, Schneeberger S, Seiler R, Brandacher G, Steurer W, Margreiter R (2000) Mitochondria in the cold. In: Life in the Cold (Heldmaier G, Klingenspor M, eds) Springer, Heidelberg, Berlin, New York:431-42.
MiPNet04.05 Titration-Injection1999-01
O2k-Protocols contents
From step titration to ramp injection: Uncoupling by FCCP with TIP.
Steurer 1999 Transplant Proc1999Steurer W, Stadlmann S, Roberts K, Fischer M, Margreiter R, Gnaiger E (1999) Quality assessment of isolated pancreatic rat islets by high-resolution respirometry. Transplant Proc 31:650.
Krumschnabel 1999 Comp Biochem Physiol C Pharmacol Toxicol Endocrinol1999Krumschnabel G, Schwarzbaum PJ, Wieser W (1999) Energetics of trout hepatocytes during A23187-induced disruption of Ca2+ homeostasis. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 124:187-195.
MiPNet02.05 DatLab2 O2Kinetics1997-01
O2k-Manual
DatLab 2. Analysis of oxygen kinetics.
Sperl 1997 Mol Cell Biochem1997Sperl W, Skladal D, Gnaiger E, Wyss M, Mayr U, Hager J, Gellerich FN (1997) High resolution respirometry of premeabilized skeletal muscle fibers in the diagnosis of neuromuscular disorders. Mol Cell Biochem 174:71-8.
Krumschnabel 1997 J Comp Physiol B1997Krumschnabel G, Biasi C, Schwarzbaum PJ, Wieser W (1997) Acute and chronic effects of temperature, and of nutritional state, on ion homeostasis and energy metabolism in teleost hepatocytes. J Comp Physiol B 167:280-6.
Steinlechner-Maran 1997 Transplantation1997Steinlechner-Maran R, Eberl T, Kunc M, Schröcksnadel H, Margreiter R, Gnaiger E (1997) Respiratory defect as an early event in preservation/reoxygenation injury in endothelial cells. Transplantation 63:136-42.
Krumschnabel 1997 Am J Physiol1997Krumschnabel G, Schwarzbaum PJ, Biasi C, Dorigatti M, Wieser W (1997) Effects of energy limitation on Ca2+ and K+ homeostasis in anoxia-tolerant and anoxia-intolerant hepatocytes. Am J Physiol 273:R307-316.
Krumschnabel 1996 Am J Physiol1996Krumschnabel G, Biasi C, Schwarzbaum PJ, Wieser W (1996) Membrane-metabolic coupling and ion homeostasis in anoxia-tolerant and anoxia-intolerant hepatocytes. Am J Physiol 270:R614-620.
Laterveer 1995 Eur J Biochem1995Laterveer FD, Gellerich FN, Nicolay K (1995) Macromolecules increase the channelling of ADP from externally associated hexokinase to the matrix of mitochondria. Eur J Biochem 232:569-77.
Wisniewski 1995 Eur J Biochem1995Wisniewski E, Gellerich FN, Kunz WS (1995) Distribution of flux control among the enzymes of mitochondrial oxidative phosphorylation in calcium-activated saponin-skinned rat musculus soleus fibers. Eur J Biochem 230:549-54.
Gellerich 1995 HRR1995Gellerich FN, Skladal D, Schranzhofer R, Lanznaster N, Kunz WS, Wisniewski E, Kuznetsov A, Krishmer M, Gnaiger E, Margreiter R, Sperl W (1995) Hochauflösende Respirometrie und multiple Substrat/Inhibitor-Titration zum funktionellen Nachweis mitochondrialer Defekte in permeabilisierten Muskelfasern. In: Molekulare Grundlage hereditärer Myopathien. (Gross M, Gresser U, Hrsg), Zuckschwerdt Verlag, München, Bern, Wien, New York:52-66.
Kunz 1994 Anal Biochem1994Kunz WS, Kuznetsov AV, Winkler K, Gellerich FN, Neuhof S, Neumann HW (1994) Measurement of fluorescence changes of NAD(P)H and fluorescent flavoproteins in saponin-skinned fibers. Anal Biochem 216:322-7.
Skladal 1994 BTK-2681994
BTK1994
Skladal D, Sperl W, Schranzhofer R, Krismer M, Gnaiger E, Margreiter R, Gellerich FN (1994) Preservation of mitochondrial functions in human skeletal muscle during storage in high energy preservation solution (HEPS). In: What is Controlling Life? (Gnaiger E, Gellerich FN, Wyss M, eds) Modern Trends in BioThermoKinetics 3. Innsbruck Univ Press:268-71.
Gellerich 1994 BTK-2631994
BTK1994
Gellerich FN, Steinlechner R, Wyss M, Eberl T, Müller LC, Skladal D, Sperl W, Dapunt O, Margreiter R, Gnaiger E (1994) Mitochondrial function in the atrial appendage of the human heart. Characterization by high-resolution respirometry. In: What is Controlling Life? (Gnaiger E, Gellerich FN, Wyss M, eds) Modern Trends in BioThermo-Kinetics 3. Innsbruck Univ Press:263-7.
Sperl 1994 J Inher Metab Dis1994Sperl W, Skladal D, Lanznaster N, Schranzhofer R, Zaunschirm G, Gnaiger E, Gellerich FN (1994) Polarographic studies of saponin-skinned muscle fibers in patients with mitochondrial myopathies. J Inher Metab Dis 17:307-10.
Haller 1994 Anal Biochem1994Haller T, Ortner M, Gnaiger E (1994) A respirometer for investigating oxidative cell metabolism. Toward optimization of respiratory studies. Anal Biochem 218:338-42.
SteinlechnerMaran 1994 BTK-2831994
BTK1994
Steinlechner-Maran R, Eberl T, Margreiter R, Gnaiger E (1994) Oxygen dependence of cellular respiration in endothelial cells: A sensitive toxicological test. In: What is Controlling Life? (Gnaiger E, Gellerich FN, Wyss M, eds) Modern Trends in BioThermo-Kinetics 3. Innsbruck Univ Press:283-7.
Knoblechner 1994 BTK-2941994
BTK1994
Knoblechner A, Steinlechner R, Schirmer M, Gellerich FN, Margreiter R, Konwalinka G, Gnaiger E (1994) The effect of 2-chlorodeoxy-adenosine on endogenous respiration of a human lymphoma cell line (U-937). In: What is Controlling Life? (Gnaiger E, Gellerich FN, Wyss M, eds) Modern Trends in BioThermoKinetics 3. Innsbruck Univ Press:294-6.
Laterveer 1994 BTK-1861994
BTK1994
Laterveer FD, Gellerich FN, Gnaiger E, Nicolay K (1994) Macromolecules increase the channeling of ADP from mitochondrially associated hexokinase to the mitochondrial matrix. In: What is Controlling Life? (Gnaiger E, Gellerich FN, Wyss M, eds) Modern Trends in BioThermoKinetics 3. Innsbruck Univ Press:186-90.
Eberl 1994 BTK-2881994
BTK1994
Eberl T, Steinlechner R, Salvenmoser W, Abendstein B, Rhomberg M, Schröcksnadel H, Schmid T, Gnaiger E, Margreiter R (1994) Endothelial cell cultures as a model for organ preservation studies. In: What is Controlling Life? (Gnaiger E, Gellerich FN, Wyss M, eds) Modern Trends in BioThermoKinetics 3. Innsbruck Univ Press:288-93.
Krumschnabel 1994 Physiol Zool1994Krumschnabel G, Schwarzbaum PJ, Wieser W (1994) Coupling of energy supply and energy demand in isolated goldfish hepatocytes. Physiol Zool 67:438-448.
Mendez 1994 BTK-1911994
BTK1994
Méndez G, Gnaiger E (1994) How does oxygen pressure control oxygen flux in isolated mitochondria? A methodological approach by high-resolution respirometry and digital data analysis. In: What is Controlling Life? (Gnaiger E, Gellerich FN, Wyss M, eds) Modern Trends in BioThermo-Kinetics 3. Innsbruck Univ Press:191-4.
Krumschnabel 1994 J Exp Biol1994Krumschnabel G, Malle S, Schwarzbaum PJ, Wieser W (1994) Glycolytic function in goldfish hepatocytes at different temperatures: relevance for Na+ pump activity and protein synthesis. J Exp Biol 193:285-90.
Gellerich 1994 BTK-1811994
BTK1994
Gellerich FN, Laterveer FD, Gnaiger E, Nicolay K (1994) Effect of macromolecules on ADP-transport into mitochondria. In: What is Controlling Life? (Gnaiger E, Gellerich FN, Wyss M, eds) Modern Trends in BioThermoKinetics 3. Innsbruck Univ Press:181-5.
Krumschnabel 1994 Experientia1994Krumschnabel G, Wieser W (1994) Inhibition of the sodium pump does not cause a stoichiometric decrease of ATP-production in energy limited fish hepatocytes. Experientia 50:483-5.
MiPNet03.03 Internat-Oxygraph-Workshops1991-
O2k-Workshops.png
Innsbruck AT, since 1991. International oxygraph workshops on high-resolution respirometry, IOC.

O2k-Abstracts

 PublishedReference
Gnaiger 2019 NatureConference2019Gnaiger E, Passrugger M, Gallee L, Felipe F Garcia-Souza, Zdrazilova L, Doerrier C (2019) High-resolution respirometry and innovations in the Oroboros O2k-technology.
Silva 2019 ESCI20192019Silva FSG, Komlodi T, Garcia-Souza LF, Bento G, Doerrier C, Oliveira PJ, Gnaiger E (2019) Can fatty acid oxidation be specifically blocked by the CPT1 inhibitor etomoxir?
Calabria 2019 MiPschool Coimbra2019
Elisa Calabria
Investigating mitochondrial function in blood cells by high resolution respirometry: contribution to an interlaboratory study. Mitoeagle WG4.
Silva 2019 MiPschool Coimbra2019
Filomena Pereira da Silva Grilo da Silva
Off-target effects of etomoxir on mitochondrial complex I.
Bastos Sant'Anna Silva 2019 Life Sciences Meeting 2019 Innsbruck AT2019Cellular succinate transport and mitochondrial respiratory function in prostate cancer.
Rutai 2019 Crit Care2019Rutai A, Fejes R, Tallósy SZ, Poles M, Juhász L, Mészáros A, Boros M, Kaszaki J (2019) Potential role of endothelin receptors in the therapy of experimental sepsis. Crit Care.
Chang 2018 Life Sciences Meeting 2018 Innsbruck AT2018pH dependence of mitochondrial respiration and H2O2 production in oral cancer cells – a pilot study.
Huete-Ortega 2018 MiPschool Tromso E22018
Maria Huete-Ortega
High-resolution respirometry: new perspectives for the study of bioenergetics in algae and plants.
Doerrier 2018 MiP2018a2018
Carolina Anneliese Doerrier
Inter-laboratory harmonization of protocols for mitochondrial function evaluation in permeabilized muscle fibers.
Meszaros 2018 EBEC20182018Tissue- and substrate-specific patterns in the oxygen kinetics of mitochondrial respiration.
Cardoso 2018 MiPschool Tromso E22018
Luiza Helena Cardoso
Concomitant respiration and ATP production measurements to analyse P»/O2 ratios at physiological normoxia.
Garcia-Souza 2018 Life Sciences Meeting 2018 Innsbruck AT2018A respirometric cell viability test for peripheral-blood mononuclear cells and platelets.
Ravasz 2018 Abstract The evolving concept of mitochondria2018Vast pools of endogenous quinones sustain NADH oxidation by Complex I during anoxia, supporting substrate-level phosphorylation in mouse liver mitochondria
Doerrier 2018 MiP2018c2018
Carolina Doerrier
Inter-laboratory study on human permeabilized myofibers: effects of fiber preparation, respiration buffer, and blebbistatin on mitochondrial respiratory capacity and oxygen limitation.
Pereira da Silva Grilo da Silva 2018 MiP20182018
Filomena Pereira da Silva Grilo da Silva
The unspecific effect of etomoxir on mitochondrial respiration.
Huete-Ortega 2018 AlgaEurope20182018Huete-Ortega M, Komlodi T, Pranger F, Gnaiger E (2018) High-resolution respirometry: new perspectives for the study of microalgae bioenergetics and applications in biotechnology. AlgaEurope2018.
Doerrier 2018 ESCI20182018
Carolina Anneliese Doerrier
High-resolution respirometry, two techniques combined in one to explore mitochondrial function in health and disease
Gnaiger 2018 AussieMit2018Komlodi T, Sobotka O, Doerrier C, Gnaiger E (2018) Mitochondrial H2O2 production is low under tissue normoxia but high at in-vitro air-level oxygen pressure - comparison of LEAK and OXPHOS states. AussieMit 2018 Melbourne AU.
Garcia-Roves 2018 MiP2018b2018
Pablo Garcia-Roves
Generating mitochondrial respirometry reference values from permeabilized mouse soleus muscle fibers. Working Group 2 report. Garcia-Roves_Presentation
Komlodi 2018b EBEC20182018Endogenous quinones sustain NADH oxidation by Complex I during anoxia, supporting substrate-level phosphorylation in mouse liver mitochondria.
Bastos Sant'Anna Silva 2018 Life Sciences Meeting 2018 Innsbruck AT2018Effect of cell-permeable succinate and malonate prodrugs on mitochondrial respiration in prostate cancer cells.
Meszaros 2018 Mt Med Hinxton2018High-resolution mitochondrial oxygen kinetics as diagnostic tool in Complex IV impairments.
Komlodi 2018 AussieMit2018Komlodi T, Hunger M, Moore AL, Gnaiger E (2018) Electron transfer at the Q-junction: new perspectives from combined measurement of mitochondrial O2 flux, H2O2 flux, and coenzyme Q redox state. AussieMit 2018 Melbourne AU.
Fischer 2018 MiPschool Tromso E22018
Christine Fischer
Analysis of mitochondrial function in iron deficiency anemia and iron overload conditions.
Bastos Sant'Anna Silva 2018 TRANSMIT Bertinoro di Romagna IT2018Cellular succinate transport and mitochondrial respiratory function in prostate cancer.
Komlodi 2018 EBEC20182018Electron supply to the Q-junction: assessment of mitochondrial respiration, H2O2 flux and the redox state of the Q-pool.
Doerrier 2018 MiP2018b2018
Carolina Doerrier
Evaluation of anaplerotic pathways to avoid artefacts in respirometric measurement of fatty acid oxidation.
Pranger 2018 Emerging Concepts in Mitochondrial Biology2018
PrangerF.JPG
High-resolution respirometry with a reduced chamber volume – which are the compromises in OXPHOS analysis?
Bastos Sant'Anna Silva 2018 MiPschool Tromso C42018
Ana Bastos Sant'Anna
Role of succinate in prostate cancer cells: uptake and mitochondrial respiratory function.
Sobotka 2018 MiP20182018
Ondrej Sobotka
Measurement of ROS production under hypoxia and unexpected methodological pitfalls of Amplex UltraRed assay.
Doerrier 2018 EBEC20182018
Carolina Anneliese Doerrier
Respiratory mapping of mitochondrial pathways for establishing a database of mitochondrial physiology.
Garipi 2018 MiPschool Tromso E22018
Garipi Enis
Phenotyping mitochondrial metabolism in Barrett’s metaplasia-dysplasia-adenocarcinoma sequence: respiratory capacity, extracelular proton flux and ROS production
Komlodi 2017 MiPschool Obergurgl2017
Timea Komlodi
Electron pressure exerted by convergent succinate- and glycerophosphate-pathways to the Q-junction regulate reversed electron transfer to Complex I and H2O2 production.
Laner 2017 Abstract EUROMIT2017 Cologne2017
EUROMIT2017
K-Regio MitoFit and MitoEAGLE – towards a global data bank on mitochondrial physiology.
Komlodi 2017 MiP20172017
Timea Komlodi
H2O2 production under hypoxia in brain and heart mitochondria: does O2 concentration matter?
Nemec 2017 MiP20172017
Michal Nemec
Three-month exercise modulates skeletal muscle mitochondria function in patients with mild cognitive impairment.
Murray 2017 Abstract MITOEAGLE Barcelona2017
COST Action MitoEAGLE
Metabolic adaptation to high altitude in Himalayan Sherpas.
Ukropec 2017 MITOEAGLE Obergurgl2017
COST Action MitoEAGLE
Could functional state of muscle mitochondria reflect exercise-induced changes in insulin sensitivity, glucose tolerance and cognitive performance in individuals with mild cognitive impairment?
Meszaros 2017 MiP20172017
Andras Meszaros
Mitochondrial oxygen kinetics as a sensitive diagnostic tool to determine apparent cytochrome c oxidase excess capacity.
Cizmarova 2017 MiP20172017
Beate Cizmarova
PBMC cryopreservation and evaluation for functional mitochondrial diagnosis.
Nemec 2017 Abstract MITOEAGLE Barcelona2017
COST Action MITOEAGLE
Functional state of mitochondria in patients with preclinical cognitive deficit.
MitoFit Open Seminar 2017-07-142017
MitoFit
Innsbruck AT, 2017 Jul 14. MitoFit Open Seminar on immune cell bioenergetics.
Investigating the role of mitochondria in healthy and psychopathological aging.
Meszaros 2017 MiPschool Obergurgl2017
Andras Meszaros
(Very) High-resolution respirometry – a deep dive into oxygen dependence of mitochondrial respiration.
Sumbalova 2017 MiP2017 WG42017
Zuzana Sumbalova
Purity of blood cell fractions in respirometric studies: peripheral blood mononuclear cells and platelets.
Garcia-Roves 2017 MiP20172017
Pablo Garcia-Roves
Mitochondrial respirometry reference values from permeabilized mouse soleus muscle fibers. MitoEAGLE WG2 pilot study. Garcia-Roves_Presentation
Doerrier 2017 Abstract MitoEAGLE Barcelona2017
COST Action MitoEAGLE
SUIT reference protocol for comparative mitochondrial physiology.
Liebscher 2017 MiPschool Obergurgl2017
Gudrun Liebscher
The LAMTOR complex in regulation of fat metabolism.
Garcia-Souza 2017 MiPschool Obergurgl2017
Luiz Garcia-Souza
Assessment of mitochondrial respiratory function in cryopreserved platelets.
Sumbalova 2017 MiP20172017
Zuzana Sumbalova
The effect of lifestyle on respiration of peripheral blood mononuclear cells and platelets.
Bufe 2017 TRACT PhD project abstract2017Metabolic profiles in normal, dysplastic and cancerous oral cells.
Doerrier 2017 MiP2017 C12017
Carolina Anneliese Doerrier
Effects of warm ischemia on cardiac mitochondria to detect specific targets by high-resolution respirometry (HRR)
Doerrier 2017 MiPschool C22017
DoerrierC.JPG
Substrate-uncoupler-inhibitor titration (SUIT) protocols – fundamental principles.
Sobotka 2017 MiPschool Obergurgl2017
Ondrej Sobotka
Reference protocols for ROS production measurements.
Gnaiger 2017 Abstract EUROMIT2017 Cologne2017
EUROMIT2017
Again not a Warburg effect - mitochondrial function in primary prostate cancer.
Garcia-Souza 2017 MiP20172017
Luiz Garcia
Short-term acclimatization to moderate altitude does not affect respiration of peripheral blood mononuclear cells and platelets.
Cizmarova 2017 MITOEAGLE Obergurgl2017
Beata Cizmarova
High-resolution respirometry and viability of cryopreserved blood cells.
Komlodi 2017 Abstract MITOEAGLE Barcelona2017
COST Action MitoEAGLE
Succinate dehydrogenase regulation via oxaloacetate in brain mitochondria.
Gnaiger 2016 Abstract EBEC Riva del Garda 20162016MitoFit and MitoEAGLE – towards a global data bank on mitochondrial physiology.
Doerrier 2016b Abstract Mito Xmas Meeting Innsbruck2016Searching for specific targets of ischemic damage of cardiac mitochondria using O2k-Fluorometry.
Gnaiger 2016 Abstract UMDF20162016Schöpf B, Schäfer G, Weber A, Talasz H, Eder IE, Klocker H, Gnaiger E (2016) Oxidative phosphorylation and mitochondrial function differ between human prostate tissue and cultured cells.
Sumbalova 2016 Abstract Mito Xmas Meeting Innsbruck2016Methods for evaluation of mitochondrial membrane potential with multi-sensor high-resolution respirometry: potentiometry vs fluorometry.
Sumbalova 2016a Abstract MitoFit Science Camp 20162016Optimizing strategies on the malate concentration in SUIT protocols.
Bezuidenhout 2016a Abstract MitoFit Science Camp 20162016Comparison of oxygen dependence of respiration in permeabilized mouse skeletal muscle fibers in two respiration media, MiR06Cr and Buffer Z containing Ctl, Cr and Blebbistatin.
Schoepf 2016 Abstract Mito Xmas Meeting Innsbruck2016Mitochondrial function in primary prostate cancer.
Chicco 2016b Abstract MitoFit Science Camp 20162016OXPHOS coupling efficiency of permeabilized muscle fibers predicts metabolic efficiency of subjects exercising at 5260 m.
Laner 2016 Abstract Mito Xmas Meeting Innsbruck2016OXPHOS and ET capacity in permeabilized fibers of canine superathletes.
Laner 2016 Abstract MitoFit Science Camp 20162016OXPHOS and ET-capacity in permeabilized fibers of canine superathletes. Analysis of HRR data presenting unexpected challenges.
Bezuidenhout 2016b Abstract MitoFit Science Camp 20162016Analysis and comparison of mitochondrial function using cooling plate or ice during mechanical separation of mouse skeletal muscle fibers.
Volani 2016 Abstract Mito Xmas Meeting Innsbruck2016Effects of systemic iron perturbations on mitochondrial activity and on cellular metabolism in vivo.
Burtscher J 2016 Abstract MitoFit Science Camp 20162016Oxidative phosphorylation in the healthy and epileptic mouse brain.
Gnaiger 2016 Abstract Mito Xmas Meeting Innsbruck2016The world as a laboratory: exploring mitochondrial fitness.
Sumbalova 2016b Abstract MitoFit Science Camp 20162016Human blood cells: isolation and HRR.
Lamberti 2016 Abstract MitoFit Science Camp 20162016Development of a reference sample for HRR.
Hoppel 2016b Abstract MitoFit Science Camp 20162016Comparison of permeabilized skeletal muscle fibers or isolated mitochondria for the detection of oxidative phosphorylation defects.
Garcia-Souza 2016 Abstract Mito Xmas Meeting Innsbruck2016Assessment of fatty acid oxidation in mouse brain and liver mitochondria.
Gnaiger 2016 Abstract SFRR Australasia 20162016Facts and artefacts in measurements of H2O2 production under hypoxia.
Krumschnabel 2016a Abstract MitoFit Science Camp 20162016O2k-Protocols: Mitochondrial preparations for HRR.
Volani 2016 Abstract MitoFit Science Camp 20162016Effects of iron imbalances on mitochondrial activity in mouse liver homogenate and permabilized rat PBMCs.
Krumschnabel 2016 Abstract Mito Xmas Meeting Innsbruck2016Establishment of a reference sample for high-resolution respirometry.
Schoepf 2016 Abstract Androgens 20162016Mitochondrial function and mitochondrial heteroplasmy levels differ between benign and malignant prostate tissue.
Doerrier 2016 Abstract MitoFit Science Camp 20162016Development of a SUIT reference protocol for OXPHOS analysis by high-resolution respirometry.
Gnaiger 2015 Abstract MiPschool Cape Town 20152015The functional design of the electron transfer system (ETS) and mitochondrial respiratory control.
Gnaiger 2015 Abstract MiP20152015Mitochondrial function of cyropreserved HEK 293T cells: development of a reference sample for high-resolution respirometry.
Laner 2015 Abstract MiPschool Cape Town 20152015The Oroboros Oxygraph-2k for high-resolution respirometry and O2k-Fluorometry: a new quality in OXPHOS analysis.
Doerrier 2015 Abstract MiP20152015Simultaneous measurement of mitochondrial respiration, hydrogen peroxide production, and NADH autofluorescence to assess mitochondrial function.
Hoppel 2015 Abstract MiPschool London 20152015Human blood cell types as study models of mitochondrial respiration and H2O2 production.
Sumbalova 2015 Abstract MiP20152015High-resolution measurement of mitochondrial membrane potential and respiration – comparison of potentiometric and fluorometric methods.
Laner 2015 Abstract MiPschool Greenville 20152015Comparative mitochondrial physiology: OXPHOS and ET capacity in permeabilized fibers of canine superathletes.
Laner 2015 Abstract MiP20152015Comparative mitochondrial physiology: OXPHOS and ET capacity in permeabilized fibers of canine superathletes.
Doerrier 2015 Abstract MiPschool Greenville 20152015"Succinate paradox" study by high resolution respirometry combined with fluorometry and spectrofluorometry: NextGen-O2k.
Volani 2015 Abstract IOC1062015Volani C, Haschka D, Demetz E, Doerrier C, Gnaiger E, Weiss G (2015) Determination of mitochondrial respiration in peripheral blood mononuclear cells. Mitochondr Physiol Network 20.10.
Hoppel 2015 Abstract MiP20152015Effects of ultramarathon performance on mitochondrial respiration in human platelets.
Burtscher 2014 Abstract MiP20142014Region-specific differences in Complex I- and Complex II-linked respiration in the mouse brain.
Schoepf 2014 Abstract MiP20142014OXPHOS analysis in small prostate biopsies.
Harrison 2014 Abstract MiP20142014The relationship between cytochrome redox state and oxygen consumption in isolated mouse and beef heart mitochondria during hypoxia.
Sumbalova 2014 Abstract MiP20142014Optimization of malate concentration for high-resolution respirometry: mitochondria from rat liver and brain.
Krumschnabel 2014 Abstract MiP20142014Simultaneous high-resolution measurement of mitochondrial respiration and hydrogen peroxide production.
Laner 2014 Abstract MiP20142014Cytochrome c flux control factor as a quality criterion in respiratory OXPHOS analysis in canine permeabilized fibers.
Laner 2013 ASMRM2013Laner V, Gradl P, Eigentler A, Fontana-Ayoub M, Fasching M, Gnaiger E (2013) The Oroboros O2k for high-resolution respirometry and O2k-Fluorometry: a new quality in OXPHOS analysis. ASMRM2013.
Gnaiger 2013 Abstract MiP20132013Gnaiger E, Søndergaard H, Munch-Andersen T, Damsgaard R, Hagen C, Díez-Sánchez C, Ara I, Wright-Paradis C, Schrauwen P, Hesselink M, Calbet J, Christiansen M, Helge JW, Saltin B, Boushel R (2013) Biochemical coupling efficiency in permeabilized fibers from arm and leg muscle in Inuit versus Caucasians: A functional test of the uncoupling hypothesis in Greenland. Mitochondr Physiol Network 18.08.
Krumschnabel 2013 Abstract MiP20132013Krumschnabel G, Eigentler A, Fontana-Ayoub M, Draxl A, Fasching M, Gnaiger E (2013) Tissue homogenates for respiratory OXPHOS analysis in comparative mitochondrial physiology: mouse and trout – heart and liver. Mitochondr Physiol Network 18.08.
Fasching 2012 Abstract Bioblast2012Fasching M, Sumbalova Z, Gnaiger E (2012) O2k-Fluorometry - a MitoCom project. Mitochondr Physiol Network 17.12.
Horvath 2012 Abstract Bioblast2012Horvath G, Eigentler A, Gnaiger E, Tretter L (2012) Respiratory substrate effects on mitochondrial membrane potential - experiments with mouse cardiac muscle homogenate. Mitochondr Physiol Network 17.12.
Harrison 2012 Abstract Bioblast2012Harrison DK, Fasching M (2012) O2k-Spectrophotometry – A MitoCom Project. Mitochondr Physiol Network 17.12.
Stoeger 2012 Abstract Bioblast2012Stoeger H, Fontana-Ayoub M, Eigentler A, Gnaiger E (2012) Cell respiration with yeast as a model. Mitochondr Physiol Network 17.12.
Sumbalova 2012 Abstract Bioblast2012Sumbalova Z, Fasching M, Gnaiger E (2012) Evaluation of mitochondrial respiration and membrane potential in mouse brain homogenate. Mitochondr Physiol Network 17.12:61.
OROBOROS 2012 Abstract Bioblast2012Oroboros (2012) 20 Years High-Resolution Respirometry – Oroboros Instruments and WGT. Mitochondr Physiol Network 17.12.
Horscroft 2012 Abstract IOC722012Horscroft JA, Kotwica AO, Ashmore T, Colleoni F, Morash AJ, Gilbert E, Gnaiger E, Martin DS, Murray AJ (2012) Mitochondrial function at altitude in lowland Europeans and highland Sherpas. Mitochondr Physiol Network 17.13.
Eigentler 2012 Abstract Bioblast2012Eigentler A, Draxl A, Fontana-Ayoub M, Gnaiger E (2012) The PBI-Shredder - an auxiliary HRR-tool for the preparation of tissue homogenates for diagnosis of mitochondrial respiratory function. Mitochondr Physiol Network 17.12.
Gnaiger 2012 Abstract Bioblast-Gentle Science2012Gnaiger E (2012) Gentle Science and the Bioblast Conference. Mitochondr Physiol Network 17.12.
Burtscher J 2012 Abstract Bioblast2012Burtscher J, Eigentler A, Gnaiger E, Schwarzer C (2012) Mitochondrial function in the mouse hippocampus. Mitochondr Physiol Network 17.12.
Sumbalova 2011 Abstract Kagoshima2011Sumbalova Z, Harrison DK, Gradl P, Fasching M, Gnaiger E (2011) Mitochondrial membrane potential, coupling control, H2O2 production, and the upper limit of mitochondrial performance. Abstract Kagoshima.
Sumbalova 2011 Abstract Bordeaux2011Sumbalova Z, Wiethuechter A, Fasching M, Gnaiger E (2011) Coupling control and substrate control of mitochondrial membrane potential and respiration in the mouse brain, and comparison with skeletal and cardiac muscle. Abstract MiP2011, Bordeaux.
Sumbalova 2011 Abstract Mitochondrial Medicine2011Sumbalova Z, Fasching M, Gnaiger E (2011) Substrate control in mitochondrial respiration and regulation of mitochondrial membrane potential. Abstract Mitochondrial Medicine Chicago.
Gnaiger 2005 Abstract MiP20052005High-resolution respirometry in small biopsies of human muscle: correlations with body mass index and age.

The O2k-Team

  • The O2k-Team is presented here in terms of the staff of Oroboros Instruments, collaborators in the Mitochondrial Physiology Research Group of Erich Gnaiger at the Medical University of Innsbruck, and company partners.
  • Philipp Gradl is the CEO of an independent company partner (WGT-Elektronik) of the O2k-Team, cooperating in the development of the O2k since 2001, responsible for the electronics, mechanics, and production.
  • Lukas Gradl is an independent company partner of the O2k-Team, cooperating in the development of DatLab since 2001.


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