US LA Baton Rouge Hand SC

US LA Baton Rouge Hand SC

O2k-Network Lab	Department of Biological Sciences Louisiana State University
Address	103 Life Sciences Bldg, 70803
City	Baton Rouge
State/Prov	Louisiana (LA)
Country	USA
Weblink	Steven C. Hand
Contact	Hand Steven C
Team	Borcar Apurva, Boswell Leaf, Moore D, Li S, Derenbecker R, Nag S
Team previous	Covi J, Kwast Kurt, Menze Michael A, Reynolds J, Patil Yuvraj, Podrabsky J
Status	O2k 2003-
Oroboros Events	MiP2013, Bioblast 2012, IOC72, IOC41, IOC35, IOC24, All MiP Society meetings, all Mipsummer Schools
Topics	Comparative physiology and biochemistry, animal bioenergetics, adaptations to anoxia and water stress, mitochondria physiology, Late embryogenesis Abundant (LEA) proteins

O2k-Publications

	Published	Reference
Patil 2024 J Exp Biol	2024	Patil YN, Gnaiger E, Landry AP, Leno ZJ, Hand SC (2024) OXPHOS capacity is diminished and the phosphorylation system inhibited during diapause in an extremophile, embryos of Artemia franciscana. J Exp Biol 227:jeb.245828. https://doi.org/10.1242/jeb.245828
Schober 2021 Sci Adv	2021	Schober FA, Moore D, Atanassov I, Moedas MF, Clemente P, Végvári Á, Fissi NE, Filograna R, Bucher AL, Hinze Y, The M, Hedman E, Chernogubova E, Begzati A, Wibom R, Jain M, Nilsson R, Käll L, Wedell A, Freyer C, Wredenberg A (2021) The one-carbon pool controls mitochondrial energy metabolism via complex I and iron-sulfur clusters. Sci Adv 7:eabf0717.
Wu 2018 Adv Sci	2018	Wu S, Zhang A, Li S, Chatterjee S, Qi R, Segura-Ibarra V, Ferrari M, Gupte A, Blanco E, Hamilton DJ (2018) Polymer functionalization of isolated mitochondria for cellular transplantation and metabolic phenotype alteration. Adv Sci 1700530.
Hamilton 2016 Am J Physiol Heart Circ Physiol	2016	Hamilton DJ, Zhang A, Li S, Cao TN, Smith JA, Vedula I, Cordero-Reyes AM, Youker KA, Torre-Amione G, Gupte AA (2016) Combination of angiotensin II and l-NG-nitroarginine methyl ester exacerbates mitochondrial dysfunction and oxidative stress to cause heart failure. Am J Physiol Heart Circ Physiol 310:H667-80.
Moore 2016 Cryobiology	2016	Moore DS, Hand SC (2016) Cryopreservation of lipid bilayers by LEA proteins from Artemia franciscana and trehalose. Cryobiology 73:240-7.
Moore 2015 PhD Thesis	2015	Moore D (2015) Biostabilization of lipid bilayers: dealing with water stress in embryos of Artemia franciscana. PhD Thesis 1-111.
Angebault 2015 Am J Hum Genet	2015	Angebault C, Guichet PO, Talmat-Amar Y, Charif M, Gerber S, Fares-Taie L, Gueguen N, Halloy F, Moore D, Amati-Bonneau P, Manes G, Hebrard M, Bocquet B, Quiles M, Piro-Mégy C, Teigell M, Delettre C, Rossel M, Meunier I, Preising M, Lorenz B, Carelli V, Chinnery PF, Yu-Wai-Man P, Kaplan J, Roubertie A, Barakat A, Bonneau D, Reynier P, Rozet JM, Bomont P, Hamel CP, Lenaers G (2015) Recessive mutations in RTN4IP1 cause isolated and syndromic optic neuropathies. Am J Hum Genet 97:754-60.
MiPNet12.11 MitoRespiration	2014-02-20	Flux control ratios in isolated mitochondria. OXPHOS capacity and respiratory control.
Stokich 2014 Cryobiology	2014	Stokich B, Osgood Q, Grimm D, Moorthy S, Chakraborty N, Menze MA (2014) Cryopreservation of hepatocyte (HepG2) cell monolayers: Impact of trehalose. Cryobiology 69:281-90.
MiPNet14.08 IOC52	2009-06-21	Baton Rouge US, 2009 Jun 21. Demo O2k-Workshop, IOC52 at MiPsummer 2009. O2k-Network Lab »US LA Baton Rouge Hand SC.
Menze 2009 J Biol Chem	2009	Menze MA, Boswell L, Toner M, Hand SC (2009) Occurrence of mitochondrial-targeted LEA gene in animals increases organelle resistance to water stress. J Biol Chem 284:10714-9.
Covi 2007 Physiol Biochem Zool	2007	Covi JA, Hand SC (2007) Energizing an invertebrate embryo: bafilomycin-dependent respiration and the metabolic cost of proton pumping by the V-ATPase. Physiol Biochem Zool 80:422-32.
Covi 2005 Thesis	2005	Covi JA (2005) V-ATPase expression and function in the brine shrimp, Artemia franciscana: Role of proton gradients in anoxia-induced quiescence. Graduate Faculty of the Louisiana State University and Agricultural and Mechanical College, Dept Biol Sc, PhD Thesis:1-101.
Reynolds 2004 Physiol Biochem Zool	2004	Reynolds JA, Hand SC (2004) Differences in isolated mitochondria are insufficient to account for respiratory depression during diapause in Artemia franciscana embryos. Physiol Biochem Zool 77:366-77.
Gnaiger 2000 Proc Natl Acad Sci U S A	2000	Gnaiger E, Méndez G, Hand SC (2000) High phosphorylation efficiency and depression of uncoupled respiration in mitochondria under hypoxia. Proc Natl Acad Sci U S A 97:11080-5. https://doi.org/10.1073/pnas.97.20.11080

O2k-Abstracts

	Published	Reference
Menze 2013 Abstract MiP2013	2013	Menze MA, Marunde MA, Samarajeewa DA, Anderson J, Li S, Hand SC (2013) Group1 LEA protein ameliorates inhibition of mitochondrial respiration in Drosophila melanogaster Kc167 cells and isolated mitochondria. Mitochondr Physiol Network 18.08.
Hand 2013 Abstract MiP2013	2013	Hand SC, Patil Y (2013) Defense against ATP depletion during the energy-limited state of diapause. Mitochondr Physiol Network 18.08.
Hand 2012 Abstract Bioblast	2012	Patil Y, Gnaiger E, Hand SC (2012) Respiration in embryo lysates reveals diminished Complex I activity and inhibition of the phosphorylation system during diapause in Artemia franciscana. Mitochondr Physiol Network 17.12.