Sumbalova Zuzana

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Short-Term Scientific Missions

Management Committee

Members

COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping

Sumbalova Zuzana

MitoPedia topics: EAGLE

COST: Member COST WG1: WG1 COST WG2: WG2 COST WG3: WG3 COST WG4: WG4 COST Mentor: Mentor

Name	Sumbalová Zuzana, PhD.
Institution	Pharmacobiochemical Laboratory of 3rd Department of Internal Medicine, Faculty of Medicine, Comenius University in Bratislava, SK Zuzana Sumbalova held the position of Principal investigator K-Regio MitoFit from February 2017 - April 2018 and has been collaborating with Oroboros Instruments for many years.
Address	Sasinkova 4, 811 08
City	Bratislava
State/Province
Country	Slovakia
Email	[email protected]
Weblink
O2k-Network Lab	AT Innsbruck Oroboros, SK Bratislava Sumbalova Z

Labels: Field of research: Basic

Publications

	Published	Reference
Timon-Gomez 2024 MitoFit	2024	Timón-Gómez A, Doerrier C, Sumbalová Z, Garcia-Souza LF, Baglivo E, Cardoso LHD, Gnaiger E (2024) Analysis of mitochondrial respiratory pathway and coupling control by substrate-uncoupler-inhibitor titration reference protocols. MitoFit Preprints 2024.8. https://doi.org/10.26124/mitofit:2024-0008
Sumbalova 2022 Front Mol Biosci	2022	Sumbalová Z, Kucharská J, Rausová Z, Palacka P, Kovalčíková E, Takácsová T, Mojto V, Navas P, Lopéz-Lluch G, Gvozdjáková A (2022) Reduced platelet mitochondrial respiration and oxidative phosphorylation in patients with post COVID-19 syndrome are regenerated after spa rehabilitation and targeted ubiquinol therapy. https://doi.org/10.3389/fmolb.2022.1016352
Gvozdjakova 2022 Environ Sci Pollut Res Int	2022	Gvozdjáková A, Sumbalová Z, Kucharská J, Rausová Z, Kovalčíková E, Takácsová T, Navas P, López-Lluch G, Mojto V, Palacka P (2022) Mountain spa rehabilitation improved health of patients with post-COVID-19 syndrome: pilot study. https://doi.org/10.1007/s11356-022-22949-2
Palacka 2021 Int J Mol Sci	2021	Palacka P, Gvozdjáková A, Rausová Z, Kucharská J, Slopovský J, Obertová J, Furka D, Furka S, Singh KK, Sumbalová Z (2021) Platelet mitochondrial bioenergetics reprogramming in patients with urothelial carcinoma. https://doi.org/10.3390/ijms23010388
Gvozdjakova 2021 PLoS One	2021	Gvozdjáková A, Sumbalová Z, Kucharská J, Szamosová M, Čápová L, Rausová Z, Vančová O, Mojto V, Langsjoen P, Palacka P (2021) Platelet mitochondrial respiration and coenzyme Q₁₀ could be used as new diagnostic strategy for mitochondrial dysfunction in rheumatoid diseases. PLoS ONE 16:e0256135.
Gvozdjakova 2020 Can J Physiol Pharmacol	2020	Gvozdjakova A, Kucharska J, Kura B, Vancova O, Rausova Z, Sumbalova Z, Ulicna O, Slezak J (2020) A new insight into the molecular hydrogen effect on coenzyme Q and mitochondrial function of rats. Can J Physiol Pharmacol 98: 29–34. doi: 10.1139/cjpp-2019-0281.
MitoEAGLE blood cells 1	2020	Åsander Frostner Eleonor, Aburel Oana M, Avram Vlad F, Calabria Elisa, Castelo Rueda Maria Paulina, Chamkha Imen, Čižmárová Beata, Danila Maria-Daniela, Doerrier Carolina, Eckert Gunter P, Ehinger Johannes K, Elmer Eskil, Garcia-Souza Luiz F, Gnaiger Erich, Hoppel Florian, Karabatsiakis Alexander, Keppner Gloria, Kidere Dita, Krako Jakovljević Nina, Labieniec-Watala Magdalena, Lelcu Theia, Micankova Petra, Michalak Slawomir, Molina Anthony JA, Pavlovic Kasja, Pichler Irene, Piel Sarah, Rousar Tomas, Rybacka-Mossakowska Joanna, Schartner Melanie, Siewiera Karolina, Silaidos Carmina, Sjövall Fredrik, Sobotka Ondrej, Sumbalova Zuzana, Swiniuch Daria, Vernerova Andrea, Volani Chiara, Vujacic-Mirski Ksenija, Watala Cezary (2020) Interlaboratory guide to mitochondrial respiratory studies with peripheral blood mononuclear cells and platelets. - Updated: 2020-03-06 - *Confirmed
BEC 2020.1 doi10.26124bec2020-0001.v1	2020	Gnaiger E et al ― MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1. https://doi.org/10.26124/bec:2020-0001.v1
Gvozdjakova 2020 Diagnostics (Basel)	2020	Gvozdjáková A, Sumbalová Z, Kucharská J, Komlósi M, Rausová Z, Vančová O, Számošová M, Mojto V (2020) Platelet mitochondrial respiration, endogenous coenzyme Q₁₀ and oxidative stress in patients with chronic kidney disease. Diagnostics (Basel) 10:176.
Gvozdjakova 2019 Bratisl Lek Listy	2019	Gvozdjakova A, Sumbalova Z, Kucharska J, Chladekova A, Rausova Z, Vancova O, Komlosi M, Ulicna O, Mojto V (2019) Platelet mitochondrial bioenergetic analysis in patients with nephropathies and non-communicable diseases: a new method. Bratisl Lek Listy 120:630-35.
Haschka 2018 Mov Disord	2018	Haschka D, Volani C, Stefani A, Tymoszuk P, Mitterling T, Holzknecht E, Heidbreder A, Coassin S, Sumbalova Z, Seifert M, Dichtl S, Theurl I, Gnaiger E, Kronenberg F, Frauscher B, Högl B, Weiss G (2018) Association of mitochondrial iron deficiency and dysfunction with idiopathic restless legs syndrome. Mov Disord 34:114-23.
Sumbalova 2018 Nova Sciences	2018	Sumbalová Z, Garcia-Souza LF, Cizmarova B, Volani C, Gnaiger E (2018) Analysis of mitochondrial function in human blood cells. In: Recent advances in mitochondrial medicine and coenzyme Q₁₀. Gvozdjáková A, Cornelissen G, Singh RB eds, Nova Sciences:255-68.
Gatterer 2018 J Sports Sci Med	2018	Gatterer H, Menz V, Salazar-Martinez E, Sumbalova Z, Garcia-Souza LF, Cizmarova B, Gnaiger E, Burtscher M (2018) Exercise performance, muscle oxygen extraction and blood cell mitochondrial respiration after repeated-sprint and sprint interval training in hypoxia: a pilot study. J Sports Sci Med 17:339-347.
Kancirova 2016 Physiol Res	2016	Kancirová I, Jašová M, Muráriková M, Sumbalová Z, Uličná O, Ravingerová T, Waczulíková I, Ziegelhöffer A, Ferko M (2016) Cardioprotection induced by remote ischemic preconditioning preserves the mitochondrial respiratory function in acute diabetic myocardium. Physiol Res 65:S611-19.
Krumschnabel 2015 Methods Mol Biol	2015	Krumschnabel G, Fontana-Ayoub M, Sumbalova Z, Heidler J, Gauper K, Fasching M, Gnaiger E (2015) Simultaneous high-resolution measurement of mitochondrial respiration and hydrogen peroxide production. Methods Mol Biol 1264:245-61. https://doi.org/10.1007/978-1-4939-2257-4_22
Ferko 2014 Physiol Res	2014	Ferko M, Kancirová I, Jašová M, Čarnická S, Muráriková M, Waczulíková I, Sumbalová Z, Kucharská J, Uličná O, Ravingerová T, Ziegelhöffer A (2014) Remote ischemic preconditioning of the heart: protective responses in functional and biophysical properties of cardiac mitochondria. Physiol Res 63:469-78.
Kancirova 2014 Cardiovascular Research Supplements	2014	Kancirova I, Jasova M, Murarikova M, Carnicka S, Sumbalova Z, Ulicna O, Vancova O, Waczulikova I. Ziegelhoffer A, Ferko M (2014) Adaptive changes of rat heart mitochondrial respiration: response of remote ischemic preconditioning. Cardiovascular Research Supplements 103:57–94.
Kancirova 2014 Cardiovasc Res	2014	Kancirova I, Jasova M, Murarikova M, Carnicka S, Sumbalova Z, Ulicna O, Vancova O, Waczulikova I, Ziegelhoffer A, Ferko M (2014) P406Adaptive changes of rat heart mitochondrial respiration: response of remote ischemic preconditioning. Cardiovasc Res 103 Suppl 1:S74-5.
Sumbalova 2010 Cell Mol Neurobiol	2010	Sumbalová Z, Kucharská J, Kristek F (2010) Losartan improved respiratory function and coenzyme Q content in brain mitochondria of young spontaneously hypertensive rats. Cell Mol Neurobiol 30:751-8
Kuzelova 2008 Gen Physiol Biophys	2008	Kuzelova M, Adameova A, Sumbalova Z, Paulikova I, Harcarová A, Svec P, Kucharska J. (2008) The effect of simvastatin on coenzyme Q and antioxidant/oxidant balance in diabetic-hypercholesterolaemic rats. Gen Physiol Biophys. 27:291-8.
Kasparova 2006 Neurochem Int	2006	Kasparová S, Sumbalová Z, Bystrický P, Kucharská J, Liptaj T, Mlynárik V, Gvozdjáková A (2006) Effect of coenzyme Q10 and vitamin E on brain energy metabolism in the animal model of Huntington's disease. Neurochem Int 48:93-9.

Abstracts

	Published	Reference
Sumbalova 2022 Abstract Bioblast	2022	8.6. «5 min» Sumbalová Zuzana, Kucharská J, Rausová Z, Palacka P, Kovalčíková E, Takácsová T, Mojto V, Navas P, López-Lluch G, Gvozdjáková A (2022) Ubiquinol supplementation accelerates the recovery of mitochondrial health of patients with post COVID-19 syndrome on mountain spa rehabilitation. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001
Sumbalova 2019b MiP2019	2019	The decline of mitochondrial respiration in isolated platelets after short-term storage.
Sumbalova 2019a MiP2019	2019	Platelet mitochondrial function, coenzyme Q₁₀, and oxidative stress in patients with chronic kidney diseases.
Calabria 2019 MiPschool Coimbra	2019	Investigating mitochondrial function in blood cells by high-resolution respirometry: contribution to an interlaboratory study. MitoEAGLE WG4.
Doerrier 2018 MiP2018b	2018	Evaluation of anaplerotic pathways to avoid artefacts in respirometric measurement of fatty acid oxidation.
Nemec 2018 MiP2018	2018	Aerobic/strength exercise intervention modulates skeletal muscle mitochondrial function in seniors.
Doerrier 2018 EBEC2018	2018	Respiratory mapping of mitochondrial pathways for establishing a database of mitochondrial physiology.
Doerrier 2018 ESCI2018	2018	High-resolution respirometry, two techniques combined in one to explore mitochondrial function in health and disease
Garcia-Souza 2018 Life Sciences Meeting 2018 Innsbruck AT	2018	A respirometric cell viability test for peripheral-blood mononuclear cells and platelets.
Laner 2017 Abstract EUROMIT2017 Cologne	2017	K-Regio MitoFit and MitoEAGLE – towards a global data bank on mitochondrial physiology.
Nemec 2017 Abstract MITOEAGLE Barcelona	2017	Functional state of mitochondria in patients with preclinical cognitive deficit.
Garcia-Souza 2017 MiPschool Obergurgl	2017	Assessment of mitochondrial respiratory function in cryopreserved platelets.
Ukropec 2017 MITOEAGLE Obergurgl	2017	Could functional state of muscle mitochondria reflect exercise-induced changes in insulin sensitivity, glucose tolerance and cognitive performance in individuals with mild cognitive impairment?
Cizmarova 2017 MiPschool Obergurgl	2017	The scope of cryopreservation in blood cells for functional mitochondrial diagnosis.
Garcia-Souza 2017 MITOEAGLE Obergurgl	2017	Towards a database on PBMC mitochondrial respiration: first steps on a literature survey linked to the MitoFit experimental data.
Cizmarova 2017 MITOEAGLE Obergurgl	2017	High-resolution respirometry and viability of cryopreserved blood cells.
Nemec 2017 MiP2017	2017	Three-month exercise modulates skeletal muscle mitochondria function in patients with mild cognitive impairment.
Cizmarova 2017 MiP2017	2017	PBMC cryopreservation and evaluation for functional mitochondrial diagnosis.
Garcia-Souza 2017 MiP2017	2017	Short-term acclimatization to moderate altitude does not affect respiration of peripheral blood mononuclear cells and platelets.
Sumbalova 2017 MiP2017 WG4	2017	Purity of blood cell fractions in respirometric studies: peripheral blood mononuclear cells and platelets.
Sumbalova 2017 MiP2017	2017	The effect of lifestyle on respiration of peripheral blood mononuclear cells and platelets.
Cizmarova 2017 Abstract MITOEAGLE Barcelona	2017	Optimization of cryopreservation of human peripheral blood mononuclear cells and platelets for high-resolution respirometry.
Komlodi 2017 Abstract MITOEAGLE Barcelona	2017	Succinate dehydrogenase regulation via oxaloacetate in brain mitochondria.
Gnaiger 2016 Abstract EBEC Riva del Garda 2016	2016	MitoFit and MitoEAGLE – towards a global data bank on mitochondrial physiology.
Doerrier 2016 Abstract MitoFit Science Camp 2016	2016	Development of a SUIT reference protocol for OXPHOS analysis by high-resolution respirometry.
Sumbalova 2016a Abstract MitoFit Science Camp 2016	2016	Optimizing strategies on the malate concentration in SUIT protocols.
Sumbalova 2016b Abstract MitoFit Science Camp 2016	2016	Human blood cells: isolation and HRR.
Sumbalova 2016 Abstract Mito Xmas Meeting Innsbruck	2016	Methods for evaluation of mitochondrial membrane potential with multi-sensor high-resolution respirometry: potentiometry vs fluorometry.
Doerrier 2016a Abstract Mito Xmas Meeting Innsbruck	2016	K-Regio MitoFit and MitoEAGLE – towards a global data bank on mitochondrial physiology.
Garcia-Souza 2016 Abstract Mito Xmas Meeting Innsbruck	2016	Assessment of fatty acid oxidation in mouse brain and liver mitochondria.
Sumbalova 2015 Abstract MiP2015	2015	High-resolution measurement of mitochondrial membrane potential and respiration – comparison of potentiometric and fluorometric methods.
Doerrier 2015 Abstract MiP2015	2015	Simultaneous measurement of mitochondrial respiration, hydrogen peroxide production, and NADH autofluorescence to assess mitochondrial function.
Doerrier 2015 Abstract MiPschool Greenville 2015	2015	"Succinate paradox" study by high resolution respirometry combined with fluorometry and spectrofluorometry: NextGen-O2k.
Krumschnabel 2014 Abstract MiP2014	2014	Simultaneous high-resolution measurement of mitochondrial respiration and hydrogen peroxide production.
Sumbalova 2014 Abstract MiP2014	2014	Optimization of malate concentration for high-resolution respirometry: mitochondria from rat liver and brain.
Sumbalova 2012 Abstract Bioblast	2012	Sumbalova Z, Fasching M, Gnaiger E (2012) Evaluation of mitochondrial respiration and membrane potential in mouse brain homogenate. Mitochondr Physiol Network 17.12:61.
Fasching 2012 Abstract Bioblast	2012	Fasching M, Sumbalova Z, Gnaiger E (2012) O2k-Fluorometry - a MitoCom project. Mitochondr Physiol Network 17.12.
Fasching IOC61-TPP group	2011	Fasching M, Sumbalova Z (2011) TPP special interest group during IOC61. MiPNet16.01.
Sumbalova 2011 Abstract Mitochondrial Medicine	2011	Sumbalova Z, Fasching M, Gnaiger E (2011) Substrate control in mitochondrial respiration and regulation of mitochondrial membrane potential. Abstract Mitochondrial Medicine Chicago.
Burtscher 2011Abstract Mitochondrial Medicine	2011	Burtscher M, Dietrich H, Gatterer H, Gnaiger E, Harrison DK, Karall D, Krismer M, Lass-Floerl C, Parson W, Perkhofer S, Pesta D, Schocke M, Sumbalova Z, Wiethüchter A (2011) Mitochondrial competence. Regional and international cooperation for establishing new standards in functional mitochondrial diagnosis. Abstract Mitochondrial Medicine Chicago.
Sumbalova 2011 Abstract Bordeaux	2011	Sumbalova Z, Wiethuechter A, Fasching M, Gnaiger E (2011) Coupling control and substrate control of mitochondrial membrane potential and respiration in the mouse brain, and comparison with skeletal and cardiac muscle. Abstract MiP2011, Bordeaux.
Sumbalova 2011 Abstract Kagoshima	2011	Sumbalova Z, Harrison DK, Gradl P, Fasching M, Gnaiger E (2011) Mitochondrial membrane potential, coupling control, H₂O₂ production, and the upper limit of mitochondrial performance. Abstract Kagoshima.

Participated at

MiPNet27.02 IOC153 Innsbruck AT

Bioblast 2022: BEC Inaugural Conference

MitoEAGLE 2019 Belgrade RS
MitoEAGLE 2019 Matrei am Brenner AT
MitoEAGLE 2018 Lund SE
MitoEAGLE 2018 Poznan PL
MitoEAGLE 2018 Innsbruck AT
IOC126 Innsbruck AT
MitoFit Workshop ATP 2017 Innsbruck AT
MitoEAGLE 2017 Hradec Kralove CZ
MitoEAGLE WG Meeting 2017 Obergurgl AT
MitoFit Open Seminar 2017 Innsbruck AT
MitoEAGLE 2017 Barcelona ES
MitoEAGLE 2016 Verona IT
MitoFit Science Camp 2016 Kuehtai AT
|IOC116 Innsbruck AT
IOC109 Schroecken AT
IOC106 Schroecken AT
IOC100 Schroecken AT
MiP2014 Obergurgl AT (MiPNet Guest Tutor)
IOC95 Obergurgl AT (MiPNet Guest Tutor)
IOC76 Prague CZ
Bioblast 2012 Innsbruck AT
IOC75 Schroecken AT (MiPNet Guest Tutor)
Oroboros Science Scholarship (February 2010-Jul 2011)
IOC61 Schroecken AT
IOC60 Schroecken AT
IOC56 Schroecken AT
IOC55 Schroecken AT
IOC54 Schroecken AT

Visiting scientist in the Oroboros O2k-Laboratory

Zuzana Sumbalova: Visiting scientist at the Oroboros O2k-Laboratory

February 2015 to June 2015 Postdoctoral Research Scholarship within Action Austria-Slovakia
September 08 to October 04 2014 within the framework of the ERASMUS trainingship programme; during this time she also participated in a malate project.