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	Year	Reference	Coupling	Pathway	Preparation	Organism	Tissue;cell
Reguis Yadao 2018 Thesis	2018	Reguis Yadao DR (2018) Smooth muscle cell mitochondrial respiration – effects of aerobic training and type I diabetes. Master's Thesis 71.	LEAK OXPHOS	N NS ROX	Permeabilized tissue	Mouse	Other cell lines
Apostolopoulou 2018 Thesis	2018	Apostolopoulou M (2018) Determinants of insulin sensitivity in obesity and recent-onset type 2 diabetes mellitus. PhD Thesis 77.	OXPHOS ET	F N NS	Homogenate Isolated mitochondria	Human	Liver
Efimova 2018 Thesis	2018	Efimova I (2018) Structural composition and functional properties of mitochondrial FoF1 ATP synthase on models of specific subunits deficiencies. PhD Thesis 94.	LEAK OXPHOS ET	N S Gp CIV NS ROX	Permeabilized cells	Human	HEK
Dechandt 2018 Am J Physiol Regul Integr Comp Physiol	2018	Dechandt CR, Vicentini TM, Lanfredi GP, da Silva RMP Jr, Espreafico EM, de Oliveira JAC, Faça VM, Garcia-Cairasco N, Alberici LC (2018) The highly efficient power house in the Wistar Audiogenic Rat (WAR), an epileptic rat strain. Am J Physiol Regul Integr Comp Physiol 316:R243-R254.	LEAK OXPHOS ET	N ROX	Permeabilized tissue Isolated mitochondria	Rat	Heart Skeletal muscle Liver
Zhang 2018 Cardiovasc Diabetol	2018	Zhang X, Zhang Z, Yang Y, Suo Y, Liu R, Qiu J, Zhao Y, Jiang N, Liu C, Tse G, Li G, Liu T (2018) Alogliptin prevents diastolic dysfunction and preserves left ventricular mitochondrial function in diabetic rabbits. Cardiovasc Diabetol 17:160.	OXPHOS LEAK	N	Isolated mitochondria	Rabbit	Heart
D'Souza 2018 J Lipid Res	2018	D'Souza K, Nzirorera C, Cowie AM, Varghese GP, Trivedi P, Eichmann TO, Biswas D, Touaibia M, Morris AJ, Aidinis V, Kane DA, Pulinilkunnil T, Kienesberger PC (2018) Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism. J Lipid Res 59:1805-17.	LEAK OXPHOS	F N S ROX	Permeabilized tissue	Mouse	Skeletal muscle
Simard 2018 J Vis Exp	2018	Simard CJ, Pelletier G, Boudreau LH, Hebert-Chatelain E, Pichaud N (2018) Measurement of mitochondrial oxygen consumption in permeabilized fibers of Drosophila using minimal amounts of tissue. J Vis Exp 134.	LEAK OXPHOS	N Gp CIV NS ROX	Permeabilized tissue	Drosophila
Giordano 2018 Am J Respir Cell Mol Biol	2018	Giordano L, Farnham A, Dhandapani PK, Salminen L, Bhaskaran J, Voswinckel R, Rauschkolb P, Scheibe S, Sommer N, Beisswenger C, Weissmann N, Braun T, Jacobs HT, Bals R, Herr C, Szibor M (2018) Alternative oxidase attenuates cigarette smoke-induced lung dysfunction and tissue damage. Am J Respir Cell Mol Biol 60:515-22.	OXPHOS	N S CIV ROX	Permeabilized cells	Mouse	Fibroblast
Dela 2018 Acta Physiol (Oxf)	2018	Dela F, Ingersen A, Andersen NB, Nielsen MB, Petersen HHH, Hansen CN, Larsen S, Wojtaszewski J, Helge JW (2018) Effects of one-legged high-intensity interval training on insulin-mediated skeletal muscle glucose homeostasis in patients with type 2 diabetes. Acta Physiol (Oxf) 226:e13245.	OXPHOS LEAK	N NS ROX	Permeabilized tissue	Human	Skeletal muscle
MacMillan-Crow 2018 Intern Med Rev (Wash D C)	2018	MacMillan-Crow LA, Mayeux PR (2018) Female mice exhibit less renal mitochondrial injury but greater mortality using a comorbid model of experimental sepsis. Intern Med Rev (Wash D C) 4.	OXPHOS LEAK	N S ROX	Permeabilized tissue	Mouse	Kidney
McLaughlin 2018 Biochem Biophys Res Commun	2018	McLaughlin KL, McClung JM, Fisher-Wellman KH (2018) Bioenergetic consequences of compromised mitochondrial DNA repair in the mouse heart. Biochem Biophys Res Commun 504:742-48.		N S F	Isolated mitochondria	Mouse	Heart
Groennebaek 2018 Front Physiol	2018	Groennebaek T, Jespersen NR, Jakobsgaard JE, Sieljacks P, Wang J, Rindom E, Musci RV, Bøtker HE, Hamilton KL, Miller BF, de Paoli FV, Vissing K (2018) Skeletal muscle mitochondrial protein synthesis and respiration increase with low-load blood flow restricted as well as high-load resistance training. Front Physiol 9:1796.	LEAK OXPHOS ET	N NS ROX	Permeabilized tissue	Human	Skeletal muscle
Eimre 2018 Oxid Med Cell Longev	2018	Eimre M, Paju K, Peet N, Kadaja L, Tarrend M, Kasvandik S, Seppet J, Ivask M, Orlova E, Kõks S (2018) Increased mitochondrial protein levels and bioenergetics in the musculus rectus femoris of Wfs1-deficient mice. Oxid Med Cell Longev 2018:3175313.	OXPHOS LEAK	N S CIV ROX	Permeabilized tissue	Mouse	Skeletal muscle
Sumbalova 2018 Nova Sciences	2018	Sumbalová Z, Garcia-Souza LF, Cizmarova B, Volani C, Gnaiger E (2018) Analysis of mitochondrial function in human blood cells. In: Recent advances in mitochondrial medicine and coenzyme Q₁₀. Gvozdjáková A, Cornelissen G, Singh RB eds, Nova Sciences:255-68.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells Intact cells	Human	Blood cells
Menezes-Filho 2018 Biochim Biophys Acta Bioenerg	2018	Menezes-Filho SL, Amigo I, Luévano-Martínez LA, Kowaltowski AJ (2018) Fasting promotes functional changes in liver mitochondria. Biochim Biophys Acta Bioenerg 1860:129-35.	OXPHOS ET	N S	Isolated mitochondria	Mouse	Liver
Tripodi 2018 Biochim Biophys Acta Mol Cell Res	2018	Tripodi F, Castoldi A, Nicastro R, Reghellin V, Lombardi L, Airoldi C, Falletta E, Maffioli E, Scarcia P, Palmieri L, Alberghina L, Agrimi G, Tedeschi G, Coccetti P (2018) Methionine supplementation stimulates mitochondrial respiration. Biochim Biophys Acta Mol Cell Res 1865:1901-13.	OXPHOS LEAK	N S	Isolated mitochondria	Saccharomyces cerevisiae
Razak 2018 RUMeS	2018	Razak SHA, Hassan H, Hakimi NH, Rani NA, Ibrahim NF, Ngah WZW, Makpol S, Damanhuri MHA, Karim NA, Tan JK (2018) Isolation of mitochondria and measurement of oxygen consumption rate by high-resolution respirometry in rat hippocampus. RUMeS 6:11-18.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Rat	Nervous system
Krug 2018 Thesis	2018	Krug KP (2018) Adaptation of metabolism and respiratory chain functions in pulmonary arterial vascular muscle cells under chronic hypoxia: especially considering the cytochrome c oxidase subunit 4 isoform 2. Doctoral Dissertation 136.	LEAK ROUTINE OXPHOS ET	N S CIV ROX	Intact cells Permeabilized cells	Rat	Other cell lines
Cardinale 2018 Thesis	2018	Cardinale DA (2018) The significance of mitochondrial respiratory function in regulating oxygen uptake and performance in humans. PhD Thesis 99.	LEAK OXPHOS	F N NS	Permeabilized tissue Isolated mitochondria	Human	Skeletal muscle
Manoharan 2018 Thesis	2018	Manoharan N (2018) Characterization of mitochondrial respiration in atlantic salmon (Salmo salar) fed with glutamate and succinate enhanced diet. Master's Thesis 52.	LEAK OXPHOS ET	N S NS ROX	Homogenate	Fishes	Heart Liver
Torres 2018 Cell Metab	2018	Torres MJ, Kew KA, Ryan TE, Pennington ER, Lin CT, Buddo KA, Fix AM, Smith CA, Gilliam LA, Karvinen S, Lowe DA, Spangenburg EE, Zeczycki TN, Shaikh SR, Neufer PD (2018) 17β-estradiol directly lowers mitochondrial membrane microviscosity and improves bioenergetic function in skeletal muscle. Cell Metab 27:167-79. https://doi.org/10.1016/j.cmet.2017.10.003	LEAK OXPHOS ET	F N S CIV NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Burstein 2018 Hum Mol Genet	2018	Burstein SR, Valsecchi F, Kawamata H, Bourens M, Zeng R, Zuberi A, Milner TA, Cloonan SM, Lutz C, Barrientos A, Manfredi G (2018) In vitro and in vivo studies of the ALS-FTLD protein CHCHD10 reveal novel mitochondrial topology and protein interactions. Hum Mol Genet 27:160-77.	LEAK OXPHOS ET	N CIV	Isolated mitochondria Intact cells	Human Mouse	Heart Skeletal muscle Nervous system HEK
Matsumoto 2018 Circulation	2018	Matsumoto J, Takada S, Kinugawa S, Furihata T, Nambu H, Kakutani N, Tsuda M, Fukushima A, Yokota T, Tanaka S, Takahashi H, Watanabe M, Hatakeyama S, Matsumoto M, Nakayama KI, Otsuka Y, Sabe H, Tsutsui H, Anzai T (2018) Brain-derived neurotrophic factor improves limited exercise capacity in mice with heart failure. Circulation 138:2064-66.	LEAK ET	N S NS	Permeabilized tissue	Mouse	Skeletal muscle
Brunetta 2018 Exp Physiol	2018	Brunetta HS, de Paula GC, de Oliveira J, Martins EL, Dos Santos GJ, Filho AG, Rafacho A, de Bem AF, Nunes EA (2018) Decrement in resting and insulin-stimulated soleus muscle mitochondrial respiration is an early event in diet-induced obesity in mice. Exp Physiol 104:306-21.	LEAK OXPHOS	N NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Rekuviene 2018 Thesis	2018	Rekuvienė E (2018) Effect of respiratory complex I inhibitors on mitochondrial permeability transition and cell viability during brain ischemia. Doctoral Dissertation 138.	LEAK OXPHOS	N S	Isolated mitochondria	Rat	Nervous system
Van der Kooij 2018 Mol Psychiatry	2018	van der Kooij MA, Hollis F, Lozano L, Zalachoras I, Abad S, Zanoletti O, Grosse J, Guillot de Suduiraut I, Canto C, Sandi C (2018) Diazepam actions in the VTA enhance social dominance and mitochondrial function in the nucleus accumbens by activation of dopamine D1 receptors. Mol Psychiatry 23:569-78.	OXPHOS ET	N S NS ROX	Homogenate	Rat	Nervous system
Hollis 2018 Neuropharmacology	2018	Hollis F, Mitchell ES, Canto C, Wang D, Sandi C (2018) Medium chain triglyceride diet reduces anxiety-like behaviors and enhances social competitiveness in rats. Neuropharmacology 138:245-56.	OXPHOS ET	N S NS ROX	Homogenate	Rat	Nervous system
Stepanova 2018 J Neurochem	2018	Stepanova A, Konrad C, Manfredi G, Springett R, Ten V, Galkin A (2018) The dependence of brain mitochondria reactive oxygen species production on oxygen level is linear, except when inhibited by antimycin A. J Neurochem 148:731-45.	LEAK OXPHOS	N S Gp NS ROX	Isolated mitochondria	Mouse	Nervous system
Mahapatra 2018 Clin Sci (Lond)	2018	Mahapatra G, Smith SC, Hughes TM, Wagner B, Maldjian JA, Freedman BI, Molina AJA (2018) Blood-based bioenergetic profiling is related to differences in brain morphology in African Americans with Type 2 diabetes. Clin Sci (Lond) 132:2509-18. https://doi.org/10.1042/CS20180690	LEAK OXPHOS ET	F N S Gp NS Other combinations ROX	Permeabilized cells	Human	Nervous system Blood cells
Siira 2018 EMBO Rep	2018	Siira SJ, Rossetti G, Richman TR, Perks K, Ermer JA, Kuznetsova I, Hughes L, Shearwood AJ, Viola HM, Hool LC, Rackham O, Filipovska A (2018) Concerted regulation of mitochondrial and nuclear non-coding RNAs by a dual-targeted RNase Z. EMBO Rep 19:e46198.	LEAK OXPHOS ET	N S	Isolated mitochondria	Mouse	Heart
Cecatto 2018 FEBS J	2018	Cecatto C, Amaral AU, da Silva JC, Wajner A, Schimit MOV, da Silva LHR, Wajner SM, Zanatta A, Castilho RF, Wajner M (2018) Metabolite accumulation in VLCAD deficiency markedly disrupts mitochondrial bioenergetics and Ca²⁺ homeostasis in the heart. FEBS J 285:1437-55.	LEAK OXPHOS ET	N S	Permeabilized cells Permeabilized tissue Isolated mitochondria	Rat	Heart Other cell lines
Dejmek 2018 Physiol Res	2018	Dejmek J, Kohoutová M, Kripnerová M, Čedíková M, Tůma Z, Babuška V, Bolek L, Kuncová J (2018) Repeated exposure to hyperbaric hyperoxia affects mitochondrial functions of the lung fibroblasts. Physiol Res 67(Suppl 4):S633-S643.	LEAK ROUTINE OXPHOS ET	F N S CIV NS ROX	Permeabilized cells Intact cells	Human	Lung;gill Fibroblast
Ruas 2018 Sci Rep	2018	Ruas JS, Siqueira-Santos ES, Rodrigues-Silva E, Castilho RF (2018) High glycolytic activity of tumor cells leads to underestimation of electron transport system capacity when mitochondrial ATP synthase is inhibited. https://doi.org/10.1038/s41598-018-35679-8	LEAK ET ROUTINE	N	Permeabilized cells Intact cells	Human	Nervous system Other cell lines
Souza 2018 Sci Rep	2018	Souza RWA, Alves CRR, Medeiros A, Rolim N, Silva GJJ, Moreira JBN, Alves MN, Wohlwend M, Gebriel M, Hagen L, Sharma A, Koch LG, Britton SL, Slupphaug G, Wisløff U, Brum PC (2018) Differential regulation of cysteine oxidative post-translational modifications in high and low aerobic capacity. Sci Rep 8:17772.	LEAK OXPHOS ET	N S NS	Permeabilized tissue	Rat	Heart Skeletal muscle
Valentine 2018 J Gerontol A Biol Sci Med Sci	2018	Valentine JM, Li ME, Shoelson SE, Zhang N, Reddick RL, Musi N (2018) NFκB regulates muscle development and mitochondrial function. J Gerontol A Biol Sci Med Sci 75:647-53.	LEAK OXPHOS ET	F N S NS	Permeabilized tissue	Mouse	Skeletal muscle
Wang 2018 J Nutr Biochem	2018	Wang Y, Fouret G, Bonafos B, Blachnio-Zabielska A, Leroy T, Crouzier D, Barea B, Gaillet S, Moro C, Lecomte J, Coudray C, Feillet-Coudray C (2018) Long-term follow-up of muscle lipid accumulation, mitochondrial activity and oxidative stress and their relationship with impaired glucose homeostasis in high fat high fructose diet-fed rats. J Nutr Biochem 64:182-97.	OXPHOS LEAK	N NS	Isolated mitochondria	Rat	Skeletal muscle
Konopka 2018 Aging Cell	2018	Konopka AR, Laurin JL, Schoenberg HM, Reid JJ, Castor WM, Wolff CA, Musci RV, Safairad OD, Linden MA, Biela LM, Bailey SM, Hamilton KL, Miller BF (2018) Metformin inhibits mitochondrial adaptations to aerobic exercise training in older adults. Aging Cell 18:e12880.	OXPHOS ET LEAK	F N NS S ROX	Permeabilized tissue	Human	Skeletal muscle
Park 2018 J Clin Invest	2018	Park H, He A, Tan M, Johnson JM, Dean JM, Pietka TA, Chen Y, Zhang X, Hsu FF, Razani B, Funai K, Lodhi IJ (2018) Peroxisome-derived lipids regulate adipose thermogenesis by mediating cold-induced mitochondrial fission. J Clin Invest 129:694-711.	OXPHOS ET LEAK	F N S	Permeabilized tissue	Mouse	Fat
Tyagi 2018 Sci Rep	2018	Tyagi A, Nguyen CU, Chong T, Michel CR, Fritz KS, Reisdorph N, Knaub L, Reusch JEB, Pugazhenthi S (2018) SIRT3 deficiency-induced mitochondrial dysfunction and inflammasome formation in the brain. Sci Rep 8:17547.	LEAK OXPHOS ET	N NS	Homogenate	Mouse	Nervous system
Havird 2018 bioRxiv	2018	Havird JC, Noe GR, Link L, Torres A, Logan DC, Sloan DB, Chicco AJ (2018) Assessing mitochondrial function in angiosperms with highly divergent mitochondrial genomes. bioRxiv doi: https://doi.org/10.1101/448902.	LEAK OXPHOS	N S CIV NS	Isolated mitochondria	Plants
Real-Hohn 2018 bioRxiv	2018	Real-Hohn A, Navegantes C, Ramos K, Ramos-Filho D, Cahuê F, Galina A, Salerno V (2018) Hexokinase: a central player in the synergism of high-intensity intermittent exercise and every-other-day intermittent fasting regimen on energy metabolism adaptations. bioRxiv doi: https://doi.org/10.1101/389668.	LEAK OXPHOS ET	N NS	Permeabilized tissue	Rat	Skeletal muscle
Harmuth 2018 Front Mol Neurosci	2018	Harmuth T, Prell-Schicker C, Weber JJ, Gellerich F, Funke C, Drießen S, Magg JCD, Krebiehl G, Wolburg H, Hayer SN, Hauser S, Krüger R, Schöls L, Riess O, Hübener-Schmid J (2018) Mitochondrial morphology, function and homeostasis are impaired by expression of an N-terminal calpain cleavage fragment of Ataxin-3. Front Mol Neurosci 11:368.	LEAK ET ROUTINE OXPHOS	N S	Homogenate Intact cells	Mouse	Fibroblast
Lu 2018 Cell Discov	2018	Lu Z, Wei X, Sun F, Zhang H, Gao P, Pu Y, Wang A, Chen J, Tong W, Li Q, Zhou X, Yan Z, Zheng H, Yang G, Huang Y, Liu D, Zhu Z (2018) Non-insulin determinant pathways maintain glucose homeostasis upon metabolic surgery. Cell Discov 4:58.	OXPHOS ET	F N ROX	Isolated mitochondria	Rat	Skeletal muscle Liver
Friederich 2018 Nat Commun	2018	Friederich MW, Timal S, Powell CA, Dallabona C, Kurolap A, Palacios-Zambrano S, Bratkovic D, Derks TGJ, Bick D, Bouman K, Chatfield KC, Damouny-Naoum N, Dishop MK, Falik-Zaccai TC, Fares F, Fedida A, Ferrero I, Gallagher RC, Garesse R, Gilberti M, González C, Gowan K, Habib C, Halligan RK, Kalfon L, Knight K, Lefeber D, Mamblona L, Mandel H, Mory A, Ottoson J, Paperna T, Pruijn GJM, Rebelo-Guiomar PF, Saada A, Sainz B Jr, Salvemini H, Schoots MH, Smeitink JA, Szukszto MJ, Ter Horst HJ, van den Brandt F, van Spronsen FJ, Veltman JA, Wartchow E, Wintjes LT, Zohar Y, Fernández-Moreno MA, Baris HN, Donnini C, Minczuk M, Rodenburg RJ, Van Hove JLK (2018) Pathogenic variants in glutamyl-tRNA^Gln amidotransferase subunits cause a lethal mitochondrial cardiomyopathy disorder. Nat Commun 9:4065.	ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells Intact cells	Human Fungi	Fibroblast
Wilmanns 2018 Mol Metab	2018	Wilmanns JC, Pandey R, Hon O, Chandran A, Schilling JM, Forte E, Wu Q, Cagnone G, Bais P, Philip V, Coleman D, Kocalis H, Archer SK, Pearson JT, Ramialison M, Heineke J, Patel HH, Rosenthal NA, Furtado MB, Costa MW (2018) Metformin intervention prevents cardiac dysfunction in a murine model of adult congenital heart disease. Mol Metab 20:102-14.	LEAK OXPHOS ET	F N NS ROX	Permeabilized tissue	Mouse	Heart
Schiffer 2018 PLoS One	2018	Schiffer TA, Christensen M, Gustafsson H, Palm F (2018) The effect of inactin on kidney mitochondrial function and production of reactive oxygen species. PLoS One 13:e0207728.	LEAK OXPHOS	N NS	Isolated mitochondria	Rat	Kidney
Kleszczynski 2018 Int J Mol Sci	2018	Kleszczyński K, Bilska B, Stegemann A, Flis DJ, Ziolkowski W, Pyza E, Luger TA, Reiter RJ, Böhm M, Slominski AT (2018) Melatonin and its metabolites ameliorate UVR-induced mitochondrial oxidative stress in human MNT-1 melanoma cells. Int J Mol Sci 19:E3786.	LEAK OXPHOS	N NS	Isolated mitochondria	Mouse	Liver
Lobo-Jarne 2018 Cell Rep	2018	Lobo-Jarne T, Nývltová E, Pérez-Pérez R, Timón-Gómez A, Molinié T, Choi A, Mourier A, Fontanesi F, Ugalde C, Barrientos A (2018) Human COX7A2L regulates complex III biogenesis and promotes supercomplex organization remodeling without affecting mitochondrial bioenergetics. Cell Rep 25:1786-99.	LEAK OXPHOS ET	N S NS ROX Gp	Permeabilized cells	Human	HEK Other cell lines
Champigny 2018 Mar Drugs	2018	Champigny CM, Cormier RPJ, Simard CJ, St-Coeur PD, Fortin S, Pichaud N (2018) Omega-3 monoacylglyceride effects on longevity, mitochondrial metabolism and oxidative stress: insights from Drosophila melanogaster. Mar Drugs 16:E453.	LEAK OXPHOS ET	N S NS ROX Gp	Permeabilized tissue	Drosophila
Falcao-Tebas 2018 J Physiol	2018	Falcão-Tebas F, Kuang J, Arceri C, Kerris JP, Andrikopoulos S, Marin EC, McConell GK (2018) Four weeks of exercise early in life reprograms adult skeletal muscle insulin resistance caused by paternal high fat diet. J Physiol 597:121-36.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Rat	Skeletal muscle
Fink 2018 J Biol Chem	2018	Fink BD, Bai F, Yu L, Sheldon RD, Sharma A, Taylor EB, Sivitz WI (2018) Oxaloacetic acid mediates ADP-dependent inhibition of mitochondrial complex II-driven respiration. J Biol Chem 293:19932-41. https://doi.org/10.1074/jbc.RA118.005144	OXPHOS	N S NS	Isolated mitochondria	Mouse	Skeletal muscle
Reutzel 2018 Oxid Med Cell Longev	2018	Reutzel M, Grewal R, Silaidos C, Zotzel J, Marx S, Tretzel J, Eckert GP (2018) Effects of long-term treatment with a blend of highly purified olive secoiridoids on cognition and brain ATP levels in aged NMRI mice. Oxid Med Cell Longev 2018:4070935.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Mouse	Nervous system
De Lima Junior 2018 EBioMedicine	2018	De Lima Junior JC, Souza GF, Moura-Assis A, Gaspar RS, Gaspar JM, Rocha AL, Ferrucci DL, Lima TI, Victório SC, Bonfante ILP, Cavaglieri CR, Pareja JC, Brunetto SQ, Ramos CD, Geloneze B, Mori MA, Silveira LR, Segundo GRS, Ropelle ER, Velloso LA (2018) Abnormal brown adipose tissue mitochondrial structure and function in IL10 deficiency. EBioMedicine 39:436-47.	LEAK ET	N	Isolated mitochondria	Mouse	Fat
Davis 2018 FASEB J	2018	Davis RAH, Deemer SE, Bergeron JM, Little JT, Warren JL, Fisher G, Smith DL Jr, Fontaine KR, Dickinson SL, Allison DB, Plaisance EP (2018) Dietary R, S-1,3-butanediol diacetoacetate reduces body weight and adiposity in obese mice fed a high-fat diet. FASEB J 33:2409-21.	LEAK OXPHOS	N NS	Permeabilized tissue	Mouse	Skeletal muscle
Singh 2018 Arch Toxicol	2018	Singh F, Zoll J, Duthaler U, Charles AL, Panajatovic MV, Laverny G, McWilliams TG, Metzger D, Geny B, Krähenbühl S, Bouitbir J (2018) PGC-1β modulates statin-associated myotoxicity in mice. Arch Toxicol 93:487-504.	OXPHOS LEAK	N S NS	Permeabilized tissue	Mouse	Skeletal muscle
Ederer 2018 Int J Mol Sci	2018	Ederer KA, Jin K, Bouslog S, Wang L, Gorman GS, Rowe GC, Abadir P, Raftery D, Moellering D, Promislow D, Jumbo-Lucioni P, De Luca M (2018) Age- and genotype-specific effects of the angiotensin-converting enzyme inhibitor lisinopril on mitochondrial and metabolic parameters in Drosophila melanogaster. Int J Mol Sci 19:3351.	LEAK OXPHOS	N	Isolated mitochondria	Drosophila
Hedges 2018 J Appl Physiol (1985)	2018	Hedges CP, Woodhead JST, Wang HW, Mitchell CJ, Cameron-Smith D, Hickey AJR, Merry TL (2018) Peripheral blood mononuclear cells do not reflect skeletal muscle mitochondrial function or adaptation to high-intensity interval training in healthy young men. J Appl Physiol (1985) 126:454-61.	LEAK OXPHOS ET	N CIV NS ROX	Permeabilized tissue Intact cells	Human	Skeletal muscle Blood cells
Hedges 2018 FASEB J	2018	Hedges CP, Bishop DJ, Hickey AJR (2018) Voluntary wheel running prevents the acidosis-induced decrease in skeletal muscle mitochondrial reactive oxygen species emission. FASEB J 33:4996-5004.	LEAK OXPHOS ET	N NS ROX	Permeabilized tissue	Rat	Skeletal muscle
Goncalves 2018 Neurotoxicology	2018	Gonçalves DF, Courtes AA, Hartmann DD, da Rosa PC, Oliveira DM, Soares FAA, Dalla Corte CL (2018) 6-Hydroxydopamine induces different mitochondrial bioenergetics response in brain regions of rat. Neurotoxicology 70:1-11.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Rat	Nervous system
Martins 2018 Oxid Med Cell Longev	2018	Martins IK, de Carvalho NR, Macedo GE, Rodrigues NR, Ziech CC, Vinadé L, Filho VMB, Menezes IA, Franco J, Posser T (2018) Anacardium microcarpum promotes neuroprotection dependently of AKT and ERK phosphorylation but does not prevent mitochondrial damage by 6-OHDA. Oxid Med Cell Longev 2018:2131895.	LEAK OXPHOS ET	N S NS ROX	Homogenate	Chicken	Nervous system
Kauppila 2018 Thesis	2018	Kauppila JHK (2018) Generating mammalian mitochondrial disease models with mitochondrial DNA mutations. PhD Thesis p120.	LEAK OXPHOS ET	N S	Isolated mitochondria	Mouse	Heart Liver
Holland 2018 Cell Death Dis	2018	Holland OJ, Cuffe JSM, Dekker Nitert M, Callaway L, Kwan Cheung KA, Radenkovic F, Perkins AV (2018) Placental mitochondrial adaptations in preeclampsia associated with progression to term delivery. Cell Death Dis 9:1150.	LEAK OXPHOS ET	N S CIV NS ROX	Permeabilized tissue	Human	Genital
Campbell 2018 Free Radic Biol Med	2018	Campbell MD, Duan J, Samuelson AT, Gaffrey MJ, Wang L, Bammler TK, Moore RJ, White CC, Kavanagh TJ, Voss JG, Szeto HH, Rabinovitch PS, Qian WJ, Marcinek DJ (2018) Improving mitochondrial function with SS-31 reverses age-related redox stress and improves exercise tolerance in aged mice. Free Radic Biol Med 134:268-81.	LEAK OXPHOS	N S CIV NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Hancock 2018 Elife	2018	Hancock M, Hafstad AD, Nabeebaccus AA, Catibog N, Logan A, Smyrnias I, Hansen SS, Lanner J, Schröder K, Murphy MP, Shah AM, Zhang M (2018) Myocardial NADPH oxidase-4 regulates the physiological response to acute exercise. Elife 7:e41044.	LEAK OXPHOS ET	F N S NS ROX	Isolated mitochondria	Mouse	Heart
Walczak 2018 FASEB J	2018	Walczak J, Dębska-Vielhaber G, Vielhaber S, Szymański J, Charzyńska A, Duszyński J, Szczepanowska J (2018) Distinction of sporadic and familial forms of ALS based on mitochondrial characteristics. FASEB J 33:4388-403.	OXPHOS LEAK ROUTINE	N S	Permeabilized cells	Human	Fibroblast
Rudnicki 2018 Elife	2018	Rudnicki M, Abdifarkosh G, Nwadozi E, Ramos SV, Makki A, Sepa-Kishi DM, Ceddia RB, Perry CG, Roudier E, Haas TL (2018) Endothelial-specific FoxO1 depletion prevents obesity-related disorders by increasing vascular metabolism and growth. Elife 7:e39780.	OXPHOS	N NS	Homogenate	Mouse	Fat
Gorgey 2018 Eur J Appl Physiol	2018	Gorgey AS, Witt O, O'Brien L, Cardozo C, Chen Q, Lesnefsky EJ, Graham ZA (2018) Mitochondrial health and muscle plasticity after spinal cord injury. Eur J Appl Physiol 119:315-31.	OXPHOS LEAK	N S CIV NS	Permeabilized tissue	Human	Skeletal muscle
Thompson 2018 EMBO Mol Med	2018	Thompson K, Mai N, Oláhová M, Scialó F, Formosa LE, Stroud DA, Garrett M, Lax NZ, Robertson FM, Jou C, Nascimento A, Ortez C, Jimenez-Mallebrera C, Hardy SA, He L, Brown GK, Marttinen P, McFarland R, Sanz A, Battersby BJ, Bonnen PE, Ryan MT, Chrzanowska-Lightowlers ZM, Lightowlers RN, Taylor RW (2018) OXA1L mutations cause mitochondrial encephalopathy and a combined oxidative phosphorylation defect. EMBO Mol Med 10:e9060.	LEAK OXPHOS	N CIV ROX Gp Other combinations	Homogenate	Drosophila
Niu 2018 Cancer Metab	2018	Niu X, Chen YJ, Crawford PA, Patti GJ (2018) Transport-exclusion pharmacology to localize lactate dehydrogenase activity within cells. Cancer Metab 6:19.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Human	HeLa
Pamenter 2018 PLoS One	2018	Pamenter ME, Lau GY, Richards JG (2018) Effects of cold on murine brain mitochondrial function. PLoS One 13:e0208453.	LEAK OXPHOS ET	N S CIV ROX	Permeabilized tissue	Mouse	Nervous system
Scaini 2018 Eur Neuropsychopharmacol	2018	Scaini G, Quevedo J, Velligan D, Roberts DL, Raventos H, Walss-Bass C (2018) Second generation antipsychotic-induced mitochondrial alterations: Implications for increased risk of metabolic syndrome in patients with schizophrenia. Eur Neuropsychopharmacol 28:369-80.	LEAK OXPHOS ET	N S NS ROX	Permeabilized cells	Human	Other cell lines Lymphocyte
Fouret 2018 Br J Nutr	2018	Fouret G, Gaillet S, Lecomte J, Bonafos B, Djohan F, Barea B, Badia E, Coudray C, Feillet-Coudray C (2018) 20-Week follow-up of hepatic steatosis installation and liver mitochondrial structure and activity and their interrelation in rats fed a high-fat-high-fructose diet. Br J Nutr 119:368-80.	OXPHOS	N NS		Rat	Liver
Hsiao 2018 Anal Biochem	2018	Hsiao CP, Hoppel C (2018) Analyzing mitochondrial function in human peripheral blood mononuclear cells. Anal Biochem 549:12-20.	OXPHOS ET	F N S DQ CIV NS ROX	Intact cells	Human	Blood cells
Corrochano 2018 Hum Mol Genet	2018	Corrochano S, Blanco G, Williams D, Wettstein J, Simon M, Kumar S, Moir L, Agnew T, Stewart M, Landman A, Kotiadis VN, Duchen MR, Wackerhage H, Rubinsztein DC, Brown SDM, Acevedo-Arozena A (2018) A genetic modifier suggests that endurance exercise exacerbates Huntington's disease. Hum Mol Genet 27:1723-31.	OXPHOS ET	N S NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Friederich-Persson 2018 Acta Physiol (Oxf)	2018	Friederich-Persson M, Persson P, Hansell P, Palm F (2018) Deletion of Uncoupling Protein-2 reduces renal mitochondrial leak respiration, intrarenal hypoxia and proteinuria in a mouse model of type 1 diabetes. Acta Physiol (Oxf) 223:e13058.	LEAK OXPHOS	N	Isolated mitochondria	Mouse	Kidney
Tetri 2018 Front Physiol	2018	Tetri LH, Diffee GM, Barton GP, Braun RK, Yoder HE, Haraldsdottir K, Eldridge MW, Goss KN (2018) Sex-specific skeletal muscle fatigability and decreased mitochondrial oxidative capacity in adult rats exposed to postnatal hyperoxia. Front Physiol 9:326.	LEAK OXPHOS ET	N S CIV ROX	Permeabilized tissue	Rat	Skeletal muscle
Marie 2018 Cell Death Dis	2018	Marie M, Bigot K, Angebault C, Barrau C, Gondouin P, Pagan D, Fouquet S, Villette T, Sahel JA, Lenaers G, Picaud S (2018) Light action spectrum on oxidative stress and mitochondrial damage in A2E-loaded retinal pigment epithelium cells. Cell Death Dis 9:287.	LEAK OXPHOS ET	N S NS	Permeabilized cells		Endothelial;epithelial;mesothelial cell
Fuhrmann 2018 Cell Mol Life Sci	2018	Fuhrmann DC, Wittig I, Dröse S, Schmid T, Dehne N, Brüne B (2018) Degradation of the mitochondrial complex I assembly factor TMEM126B under chronic hypoxia. Cell Mol Life Sci 75:3051-67.	LEAK ROUTINE OXPHOS ET	N S ROX	Isolated mitochondria Intact cells	Human
Geffroy 2018 Biochim Biophys Acta	2018	Geffroy G, Benyahia R, Frey S, Desquiret-Dumas V, Gueguen N, Bris C, Belal S, Inisan A, Renaud A, Chevrollier A, Henrion D, Bonneau D, Letournel F, Lenaers G, Reynier P, Procaccio V (2018) The accumulation of assembly intermediates of the mitochondrial complex I matrix arm is reduced by limiting glucose uptake in a neuronal-like model of MELAS syndrome. Biochim Biophys Acta 1864:1596-1608.	ROUTINE ET	N	Intact cells	Human	Nervous system Other cell lines
Sokolov 2018 Mitochondrion	2018	Sokolov EP, Sokolova IM (2018) Compatible osmolytes modulate mitochondrial function in a marine osmoconformer Crassostrea gigas (Thunberg, 1793). Mitochondrion 45:29-37.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Molluscs	Lung;gill
Arena 2018 Mol Cell	2018	Arena G, Cissé MY, Pyrdziak S, Chatre L, Riscal R, Fuentes M, Arnold JJ, Kastner M, Gayte L, Bertrand-Gaday C, Nay K, Angebault-Prouteau C, Murray K, Chabi B, Koechlin-Ramonatxo C, Orsetti B, Vincent C, Casas F, Marine JC, Etienne-Manneville S, Bernex F, Lombès A, Cameron CE, Dubouchaud H, Ricchetti M, Linares LK, Le Cam L (2018) Mitochondrial MDM2 regulates respiratory complex I activity independently of p53. Mol Cell 69:594-609.	OXPHOS	N S NS	Permeabilized cells	Human	Lung;gill Other cell lines
De Sales 2018 Molecules	2018	de Sales NFF, Silva da Costa L, Carneiro TIA, Minuzzo DA, Oliveira FL, Cabral LMC, Torres AG, El-Bacha T (2018) Anthocyanin-rich grape pomace extract (Vitis vinifera L.) from wine industry affects mitochondrial bioenergetics and glucose metabolism in human hepatocarcinoma HepG2 cells. Molecules 23.	LEAK ROUTINE ET	N	Intact cells	Human	Liver Other cell lines
Lica 2018 Stem Cells Dev	2018	Lica JJ, Grabe GJ, Heldt M, Misiak M, Bloch P, Serocki M, Switalska M, Wietrzyk J, Baginski M, Hellmann A, Borowski E, Skladanowski A (2018) Cell density-dependent cytological stage profile and its application for a screen of cytostatic agents active towards Leukemic Stem Cells. Stem Cells Dev 27:488-513.	LEAK ROUTINE ET	N		Human Mouse	Heart Blood cells Other cell lines
Guitart-Mampel 2018 Biochim Biophys Acta	2018	Guitart-Mampel M, Gonzalez-Tendero A, Niñerola S, Morén C, Catalán-Garcia M, González-Casacuberta I, Juárez-Flores DL, Ugarteburu O, Matalonga L, Cascajo MV, Tort F, Cortés A, Tobias E, Milisenda JC, Grau JM, Crispi F, Gratacós E, Garrabou G, Cardellach F (2018) Cardiac and placental mitochondrial characterization in a rabbit model of intrauterine growth restriction. Biochim Biophys Acta 1862:1157-67.		N ROX	Permeabilized tissue	Rabbit	Heart Genital
Doerrier 2018 Methods Mol Biol	2018	Doerrier C, Garcia-Souza LF, Krumschnabel G, Wohlfarter Y, Mészáros AT, Gnaiger E (2018) High-Resolution FluoRespirometry and OXPHOS protocols for human cells, permeabilized fibers from small biopsies of muscle, and isolated mitochondria. Methods Mol Biol 1782:31-70. https://doi.org/10.1007/978-1-4939-7831-1_3	LEAK ROUTINE OXPHOS ET	F N S Gp CIV NS Other combinations ROX	Permeabilized cells Permeabilized tissue Homogenate Isolated mitochondria Intact cells	Human Mouse Rat Saccharomyces cerevisiae	Heart Skeletal muscle Endothelial;epithelial;mesothelial cell Blood cells HEK Platelet
Magnifico 2018 Oxid Med Cell Longev	2018	Magnifico MC, Xhani M, Popov M, Saso L, Sarti P, Arese M (2018) Nonylphenol and octylphenol differently affect cell redox balance by modulating the nitric oxide signaling. Oxid Med Cell Longev 2018:1684827.	ROUTINE OXPHOS	N S CIV ROX	Permeabilized cells Intact cells	Human	Liver Other cell lines
Coleman 2018 Sci Rep	2018	Coleman V, Sa-Nguanmoo P, Koenig J, Schulz TJ, Grune T, Klaus S, Kipp AP, Ost M (2018) Partial involvement of Nrf2 in skeletal muscle mitohormesis as an adaptive response to mitochondrial uncoupling. Sci Rep 8:2446.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Chicco 2018 J Biol Chem	2018	Chicco AJ, Le CH, Gnaiger E, Dreyer HC, Muyskens JB, D'Alessandro A, Nemkov T, Hocker AD, Prenni JE, Wolfe LM, Sindt NM, Lovering AT, Subudhi AW, Roach RC (2018) Adaptive remodeling of skeletal muscle energy metabolism in high-altitude hypoxia: Lessons from AltitudeOmics. J Biol Chem 293:6659-71.	LEAK OXPHOS ET	F N S	Permeabilized tissue	Human	Skeletal muscle
Bhaskaran 2018 EMBO Rep	2018	Bhaskaran S, Pharaoh G, Ranjit R, Murphy A, Matsuzaki S, Nair BC, Forbes B, Gispert S, Auburger G, Humphries KM, Kinter M, Griffin TM, Deepa SS (2018) Loss of mitochondrial protease ClpP protects mice from diet-induced obesity and insulin resistance. EMBO Rep 19. pii: e45009.	LEAK OXPHOS	N S NS		Mouse	Fat
Logan 2018 Mol Metab	2018	Logan S, Pharaoh GA, Marlin MC, Masser DR, Matsuzaki S, Wronowski B, Yeganeh A, Parks EE, Premkumar P, Farley JA, Owen DB, Humphries KM, Kinter M, Freeman WM, Szweda LI, Van Remmen H, Sonntag WE (2018) Insulin-like growth factor receptor signaling regulates working memory, mitochondrial metabolism, and amyloid-β uptake in astrocytes. Mol Metab 9:141-55.	LEAK OXPHOS	N S NS	Isolated mitochondria	Mouse	Nervous system
Holloway 2018 Cell Rep	2018	Holloway GP, Holwerda AM, Miotto PM, Dirks ML, Verdijk LB, van Loon LJC (2018) Age-associated impairments in mitochondrial ADP sensitivity contribute to redox stress in senescent human skeletal muscle. Cell Rep 22:2837–48.	OXPHOS ET LEAK	N S NS	Permeabilized tissue	Human	Skeletal muscle
Rampello 2018 Microb Cell	2018	Rampello NG, Stenger M, Westermann B, Osiewacz HD (2018) Impact of F₁F_o-ATP-synthase dimer assembly factors on mitochondrial function and organismic aging. Microb Cell 5:198–207.	OXPHOS	N CIV	Isolated mitochondria	Fungi
Scheiber 2018 J Cardiovasc Transl Res	2018	Scheiber D, Zweck E, Jelenik T, Horn P, Albermann S, Masyuk M, Boeken U, Saeed D, Kelm M Roden M, Szendroedi J, Westenfeld R (2018) Reduced myocardial mitochondrial ROS production in mechanically unloaded hearts. J Cardiovasc Transl Res 12:107-15.	LEAK OXPHOS ET	F N NS ROX	Permeabilized tissue	Human	Heart
Rodriguez-Nuevo 2018 EMBO J	2018	Rodríguez-Nuevo A, Díaz-Ramos A, Noguera E, Díaz-Sáez F, Duran X, Muñoz JP, Romero M, Plana N, Sebastián D, Tezze C, Romanello V, Ribas F, Seco J, Planet E, Doctrow SR, González J, Borràs M, Liesa M, Palacín M, Vendrell J, Villarroya F, Sandri M, Shirihai O, Zorzano A (2018) Mitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency. EMBO J 37.	LEAK ROUTINE OXPHOS ET	N S NS	Permeabilized tissue	Mouse	Skeletal muscle
Bradley 2018 Biochim Biophys Acta	2018	Bradley RM, Bloemberg D, Aristizabal Henao JJ, Hashemi A, Mitchell AS, Fajardo VA, Bellissimo C, Mardian EB, Bombardier E, Paré MF, Moes KA, Stark KD, Tupling AR, Quadrilatero J, Duncan RE (2018) Lpaatδ/Agpat4 deficiency impairs maximal force contractility in soleus and alters fiber type in extensor digitorum longus muscle. Biochim Biophys Acta 1863:700-11.	LEAK OXPHOS ET	N S CIV NS	Permeabilized tissue	Mouse	Skeletal muscle
Ahn 2018 Redox Biol	2018	Ahn B, Pharaoh G, Premkumar P, Huseman K, Ranjit R, Kinter M, Szweda L, Kiss T, Fulop G, Tarantini S, Csiszar A, Ungvari Z, Van Remmen H (2018) Nrf2 deficiency exacerbates age-related contractile dysfunction and loss of skeletal muscle mass. Redox Biol 17:47-58.	LEAK OXPHOS	N S CIV NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Perks 2018 Cell Rep	2018	Perks KL, Rossetti G, Kuznetsova I, Hughes LA, Ermer JA, Ferreira N, Busch JD, Rudler DL, Spahr H, Schöndorf T, Shearwood AJ, Viola HM, Siira SJ, Hool LC, Milenkovic D, Larsson NG, Rackham O, Filipovska A (2018) PTCD1 is required for 16S rRNA maturation complex stability and mitochondrial ribosome assembly. Cell Rep 23:127-42.	LEAK OXPHOS ET	N Gp S	Isolated mitochondria	Mouse	Heart
Rajkumar 2018 Metabolism	2018	Rajkumar A, Liaghati A, Chan J, Lamothe G, Dent R, Doucet É, Rabasa-Lhoret R, Prud'homme D, Harper ME, Tesson F (2018) ACSL5 genotype influence on fatty acid metabolism: a cellular, tissue, and whole-body study. Metabolism 83:271-9.	OXPHOS ET	F N CIV NS	Permeabilized cells	Human Mouse	Skeletal muscle Other cell lines
Zhang 2018 J Mol Cell Cardiol	2018	Zhang G, Sheng M, Wang J, Teng T, Sun Y, Yang Q, Xu Z (2018) Zinc improves mitochondrial respiratory function and prevents mitochondrial ROS generation at reperfusion by phosphorylating STAT3 at Ser⁷²⁷. J Mol Cell Cardiol 118:169-82.	LEAK ROUTINE OXPHOS ET	N S NS	Permeabilized cells Isolated mitochondria	Mouse	Heart
Teulier 2018 J Fish Biol	2018	Teulier L, Guillard L, Leon C, Romestaing C, Voituron Y (2018) Consequences of electroshock-induced narcosis in fish muscle: from mitochondria to swim performance. J Fish Biol 92:1805-18.	OXPHOS ET	N NS ROX	Intact cells	Fishes Zebrafish	Skeletal muscle
Wuest 2018 Cell Metab	2018	Wüst S, Dröse S, Heidler J, Wittig I, Klockner I, Franko A, Bonke E, Günther S, Gärtner U, Boettger T, Braun T (2018) Metabolic maturation during muscle stem cell differentiation is achieved by miR-1/133a-mediated inhibition of the Dlk1-Dio3 mega gene cluster. Cell Metab 27:1026-39.	OXPHOS	N S CIV	Intact cells	Mouse	Skeletal muscle
Becker 2018 EMBO Rep	2018	Becker C, Kukat A, Szczepanowska K, Hermans S, Senft K, Brandscheid CP, Maiti P, Trifunovic A (2018) CLPP deficiency protects against metabolic syndrome but hinders adaptive thermogenesis. EMBO Rep 19. pii: e45126.	LEAK OXPHOS ET	F N S NS ROX	Isolated mitochondria	Mouse	Liver Fat
Chabi 2018 J Bioenerg Biomembr	2018	Chabi B, Fouret G, Lecomte J, Cortade F, Pessemesse L, Baati N, Coudray C, Lin L, Tong Q, Wrutniak-Cabello C, Casas F, Feillet-Coudray C (2018) Skeletal muscle overexpression of short isoform Sirt3 altered mitochondrial cardiolipin content and fatty acid composition. J Bioenerg Biomembr 50:131-42.	LEAK OXPHOS	N S CIV NS	Homogenate Isolated mitochondria	Mouse	Skeletal muscle
Bjoerndal 2018 Nutr Metab (Lond)	2018	Bjørndal B, Alterås EK, Lindquist C, Svardal A, Skorve J, Berge RK (2018) Associations between fatty acid oxidation, hepatic mitochondrial function, and plasma acylcarnitine levels in mice. Nutr Metab (Lond) 15:10.	OXPHOS ET	F N ROX	Homogenate	Mouse	Liver
Mendes 2018 Mol Neurobiol	2018	Mendes Lima JP, Rayêe D, Silva-Rodrigues T, Ribeiro Paes Pereira P, Mendonca APM, Rodrigues-Ferreira C, Szczupak D, Fonseca A, Oliveira MF, Souza Lima FR, Lent R, Galina A, Uziel D (2018) Perinatal asphyxia and brain development: mitochondrial damage without anatomical or cellular losses. Mol Neurobiol doi.org/10.1007/s12035-018-1019-7.	LEAK ROUTINE ET	N NS ROX	Intact cells	Rat	Nervous system
Garcia-Roche 2018 Redox Biol	2018	García-Roche M, Casal A, Carriquiry M, Radi R, Celia Quijano C, Cassina A (2018) Respiratory analysis of coupled mitochondria in cryopreserved liver biopsies. Redox Biol 17:207-12.	LEAK OXPHOS ET	N NS ROX S	Permeabilized tissue	Rat Bovines	Liver
Mikulas 2018 Dent Mater	2018	Mikulás K, Hermann P, Gera I, Komlódi T, Horváth G, Ambrus A, Tretter L (2018) Triethylene glycol dimethacrylate impairs bioenergetic functions and induces oxidative stress in mitochondria via inhibiting respiratory Complex I. Dent Mater 34:e166-e181.	OXPHOS ET	N S	Isolated mitochondria	Guinea pig	Nervous system
Bouwkamp 2018 Neurol Genet	2018	Bouwkamp CG, Afawi Z, Fattal-Valevski A, Krabbendam IE, Rivetti S, Masalha R, Quadri M, Breedveld GJ, Mandel H, Tailakh MA, Beverloo HB, Stevanin G, Brice A, van IJcken WFJ, Vernooij MW, Dolga AM, de Vrij FMS, Bonifati V, Kushner SA (2018) ACO2 homozygous missense mutation associated with complicated hereditary spastic paraplegia. Neurol Genet 4:e223.	OXPHOS ET	N	Isolated mitochondria	Human
Zhang 2018 J Gerontol A Biol Sci Med Sci	2018	Zhang X, Trevino MB, Wang M, Gardell SJ, Ayala JE, Han X, Kelly DP, Goodpaster BH, Vega RB, Coen PM (2018) Impaired mitochondrial energetics characterize poor early recovery of muscle mass following hind limb unloading in old mice. J Gerontol A Biol Sci Med Sci 73:1313-22.	LEAK OXPHOS	F N NS		Mouse	Skeletal muscle
Chen 2018 Hum Mol Genet	2018	Chen A, Tiosano D, Guran T, Baris HN, Bayram Y, Mory A, Shapiro-Kulnane L, Hodges CA, Coban Akdemir Z, Turan S, Jhangiani SN, van den Akker F, Hoppel CL, Salz HK, Lupski JR, Buchner DA (2018) Mutations in the mitochondrial ribosomal protein MRPS22 lead to primary ovarian insufficiency. Hum Mol Genet 27:1913-26.	OXPHOS ET	F N S DQ CIV NS	Isolated mitochondria	Human	Endothelial;epithelial;mesothelial cell Fibroblast
Zimin 2018 Br J Anaesth	2018	Zimin PI, Woods CB, Kayser EB, Ramirez JM, Morgan PG, Sedensky MM (2018) Isoflurane disrupts excitatory neurotransmitter dynamics via inhibition of mitochondrial complex I. Br J Anaesth 120:1019-32.	OXPHOS LEAK	N S ROX	Isolated mitochondria	Mouse	Nervous system
Van Erp 2018 Sci Rep	2018	Van Erp AC, Rebolledo RA, Hoeksma D, Jespersen NR, Ottens PJ, Nørregaard R, Pedersen M, Laustsen C, Burgerhof JGM, Wolters JC, Ciapaite J, Bøtker HE, Leuvenink HGD, Jespersen B (2018) Organ-specific responses during brain death: increased aerobic metabolism in the liver and anaerobic metabolism with decreased perfusion in the kidneys. Sci Rep 8:4405.	OXPHOS ET	F N S NS	Isolated mitochondria	Rat	Liver Kidney
Braz-Mota 2018 Sci Total Environ	2018	Braz-Mota S, Campos DF, MacCormack TJ, Duarte RM, Val AL, Almeida-Val VMF (2018) Mechanisms of toxic action of copper and copper nanoparticles in two Amazon fish species: Dwarf cichlid (Apistogramma agassizii) and cardinal tetra (Paracheirodon axelrodi). Sci Total Environ 630:1168-80.	LEAK OXPHOS ET	N NS ROX		Fishes	Lung;gill
Zhuang 2018 Thesis	2018	Zhuang Y (2018) Potential application of alternative oxidase (AOX) in neurodegenerative diseases. Master's Thesis p71.	OXPHOS	N S CIV ROX	Isolated mitochondria	Mouse	Nervous system
Allard 2018 J Clin Endocrinol Metab	2018	Allard NAE, Schirris TJJ, Verheggen RJ, Russel FGM, Rodenburg RJ, Smeitink JAM, Thompson PD, Hopman MTE, Timmers S (2018) Statins affect skeletal muscle performance: evidence for disturbances in energy metabolism. J Clin Endocrinol Metab 103:75-84.	OXPHOS	F N S Gp CIV NS	Permeabilized tissue	Human	Skeletal muscle
Martins 2018 Comp Biochem Physiol B Biochem Mol Biol	2018	Martins EL, Ricardo JC, de-Souza-Ferreira E, Camacho-Pereira J, Ramos-Filho D, Galina A (2018) Rapid regulation of substrate use for oxidative phosphorylation during a single session of high intensity interval or aerobic exercises in different rat skeletal muscles. Comp Biochem Physiol B Biochem Mol Biol 217:40-50.	LEAK OXPHOS ET	F N NS ROX	Permeabilized tissue	Rat	Skeletal muscle
De Paula Martins 2018 Free Radic Biol Med	2018	de Paula Martins R, Ghisoni K, Lim CK, Aguiar AS Jr, Guillemin GJ, Latini A (2018) Neopterin preconditioning prevents inflammasome activation in mammalian astrocytes. Free Radic Biol Med 115:371-82.	ROUTINE	N		Rat	Nervous system
Koit 2018 US Patent	2018	Koit A, Kaambre T (2018) Method for selecting patients responsive for cancer treatments. US Patent US20180017547A1.	OXPHOS	F N NS	Permeabilized cells	Human
Thrush 2018 Int J Obes (Lond)	2018	Thrush AB, Antoun G, Nikpay M, Patten DA, DeVlugt C, Mauger JF, Beauchamp BL, Lau P, Reshke R, Doucet É, Imbeault P, Boushel R, Gibbings D, Hager J, Valsesia A, Slack R, Al-Dirbashi OY, Dent R, McPherson R, Harper ME (2018) Diet-resistant obesity is characterized by a distinct plasma proteomic signature and impaired muscle fiber metabolism. Int J Obes (Lond) 42:353-62.	LEAK OXPHOS ET	F N CIV NS ROX	Permeabilized tissue	Human	Skeletal muscle
Cejvanovic 2018 Free Radic Biol Med	2018	Cejvanovic V, Kjær LK, Bergholdt HKM, Torp-Pedersen A, Henriksen T, Weimann A, Ellervik C, Poulsen HE (2018) Iron induced RNA-oxidation in the general population and in mouse tissue. Free Radic Biol Med 115:127-35.	OXPHOS	N NS	Permeabilized tissue	Mouse	Skeletal muscle
Distefano 2018 J Cachexia Sarcopenia Muscle	2018	Distefano G, Standley RA, Zhang X, Carnero EA, Yi F, Cornnell HH, Coen PM (2018) Physical activity unveils the relationship between mitochondrial energetics, muscle quality, and physical function in older adults. J Cachexia Sarcopenia Muscle 9:279-94.	LEAK OXPHOS ET	F N NS	Permeabilized tissue	Human	Skeletal muscle
Docherty 2018 Atherosclerosis	2018	Docherty CK, Carswell A, Friel E, Mercer JR (2018) Impaired mitochondrial respiration in human carotid plaque atherosclerosis: A potential role for Pink1 in vascular smooth muscle cell energetics. Atherosclerosis 268:1-11.	OXPHOS	N CIV NS ROX	Permeabilized tissue	Human	Endothelial;epithelial;mesothelial cell
Chen 2018 Endocrinology	2018	Chen Y, McCommis KS, Ferguson D, Hall AM, Harris CA, Finck BN (2018) Inhibition of the mitochondrial pyruvate carrier by tolylfluanid. Endocrinology 159:609-21.	OXPHOS	N NS	Isolated mitochondria	Mouse	Fat
Petiz 2018 Chem Biol Interact	2018	Petiz LL, Pires ADRA, Echevarria A, Rodrigues-Santos CE, Eliane Merlin Rocha M, Acco A, Cadena SMSC (2018) Effects of a new antiprotozoal drug, N,N'-diphenyl-4-methoxy-benzamidine, on energy-linked functions of rat liver mitochondria. Chem Biol Interact 279:34-42.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Rat	Liver
Monaco 2018 Diabetologia	2018	Monaco CMF, Proudfoot R, Miotto PM, Herbst EAF, MacPherson REK, Holloway GP (2018) α-linolenic acid supplementation prevents exercise-induced improvements in white adipose tissue mitochondrial bioenergetics and whole-body glucose homeostasis in obese Zucker rats. Diabetologia 61:433-44.		F N	Permeabilized tissue	Rat	Skeletal muscle Fat
Shen 2018 Biosci Rep	2018	Shen NY, Ng SY, Toepp SL, Ljubicic V (2018) Protein arginine methyltransferase expression and activity during myogenesis. Biosci Rep 38. pii: BSR20171533.	OXPHOS	N NS	Permeabilized cells	Mouse	Skeletal muscle
Dawson 2018 Acta Physiol (Oxf)	2018	Dawson NJ, Lyons SA, Henry DA, Scott GR (2018) Effects of chronic hypoxia on diaphragm function in deer mice native to high altitude. Acta Physiol (Oxf) 223:e13030.	LEAK OXPHOS	N CIV NS	Permeabilized tissue	Other mammals	Skeletal muscle
Sirsat 2018 Comp Biochem Physiol A Mol Integr Physiol	2018	Sirsat SKG, Dzialowski EM (2018) Ontogeny of skeletal and cardiac muscle mitochondria oxygen fluxes in two breeds of chicken. Comp Biochem Physiol A Mol Integr Physiol 215:20-7.	LEAK OXPHOS	N S CIV NS ROX	Permeabilized tissue	Birds	Heart Skeletal muscle
De Medeiros 2018 Biochim Biophys Acta	2018	de Medeiros WA, da Silva LA, Dall'Igna DM, Michels M, Manfredini A, Dos Santos Cardoso J, Constantino L, Scaini G, Vuolo F, Streck EL, Ritter C, Dal-Pizzol F (2018) N-acetylcysteine effects on a murine model of chronic critical limb ischemia. Biochim Biophys Acta 1864:454-63.	OXPHOS	F N NS		Rat
Galvan 2018 Biochim Biophys Acta	2018	Galván AE, Chalón MC, Schurig-Briccio LA, Salomón RA, Minahk CJ, Gennis RB, Bellomio A (2018) Cytochromes bd-I and bo3 are essential for the bactericidal effect of microcin J25 on Escherichia coli cells. Biochim Biophys Acta 1859:110-8.		N		Eubacteria
Jang 2018 Intensive Care Med Exp	2018	Jang DH, MD, Khatri UG, Shortal BP, Kelly M, Lambert DS, Hardy K, Eckmann DM (2018) Alterations in mitochondrial respiration and reactive oxygen species in patients poisoned with carbon monoxide treated with hyperbaric oxygen. Intensive Care Med Exp 6:4.	LEAK OXPHOS ET	N S Gp CIV NS ROX	Permeabilized cells	Human	Blood cells
Goncalves 2018 Life Sci	2018	Gonçalves DF, de Carvalho NR, Leite MB, Courtes AA, Hartmann DD, Stefanello ST, da Silva IK, Franco JL, Soares FAA, Dalla Corte CL (2018) Caffeine and acetaminophen association: Effects on mitochondrial bioenergetics. Life Sci 193:234-41.	LEAK OXPHOS	N S NS ROX	Homogenate	Mouse	Liver
Ignatenko 2018 Nat Commun	2018	Ignatenko O, Chilov D, Paetau I, de Miguel E, Jackson CB, Capin G, Paetau A, Terzioglu M, Euro L, Suomalainen A (2018) Loss of mtDNA activates astrocytes and leads to spongiotic encephalopathy. Nat Commun 9:70.	OXPHOS ET	N CIV NS	Homogenate	Mouse	Nervous system
Weisz 2018 Hum Mol Genet	2018	Weisz ED, Towheed A, Monyak RE, Toth MS, Wallace DC, Jongens TA (2018) Loss of Drosophila FMRP leads to alterations in energy metabolism and mitochondrial function. Hum Mol Genet 27:95-106.	OXPHOS ET LEAK	N S NS ROX	Isolated mitochondria	Drosophila	Skeletal muscle
Ko 2018 Pflugers Arch	2018	Ko TH, Marquez JC, Kim HK, Jeong SH, Lee S, Youm JB, Song IS, Seo DY, Kim HJ, Won DN, Cho KI, Choi MG, Rhee BD, Ko KS, Kim N, Won JC, Han J (2018) Resistance exercise improves cardiac function and mitochondrial efficiency in diabetic rat hearts. Pflugers Arch 470:263-75.	LEAK OXPHOS	N ROX	Isolated mitochondria	Rat	Heart
Warnsmann 2018 Mech Ageing Dev	2018	Warnsmann V, Meyer N, Hamann A, Kögel D, Osiewacz HD (2018) A novel role of the mitochondrial permeability transition pore in (-)-gossypol-induced mitochondrial dysfunction. Mech Ageing Dev 170:45-58.	LEAK OXPHOS ET	N	Isolated mitochondria	Fungi
Hoffmann 2018 Sci Rep	2018	Hoffmann C, Höckele S, Kappler L, Hrabĕ de Angelis M, Häring HU, Weigert C (2018) The effect of differentiation and TGFβ on mitochondrial respiration and mitochondrial enzyme abundance in cultured primary human skeletal muscle cells. Sci Rep 8:737.	OXPHOS ET	F N S NS ROX	Permeabilized cells	Human	Skeletal muscle
Song 2018 Proc Natl Acad Sci U S A	2018	Song E, Ramos SV, Huang X, Liu Y, Botta A, Sung HK, Turnbull PC, Wheeler MB, Berger T, Wilson DJ, Perry CGR, Mak TW, Sweeney G (2018) Holo-lipocalin-2-derived siderophores increase mitochondrial ROS and impair oxidative phosphorylation in rat cardiomyocytes. Proc Natl Acad Sci U S A 115:1576-81.	LEAK OXPHOS ET	N S NS	Intact cells	Rat	Heart
Augustynek 2018 Int J Mol Sci	2018	Augustynek B, Koprowski P, Rotko D, Kunz WS, Szewczyk A, Kulawiak B (2018) Mitochondrial BK channel openers CGS7181 and CGS7184 exhibit cytotoxic properties. Int J Mol Sci 19. pii: E353.	OXPHOS	N	Isolated mitochondria	Rat	Nervous system
Schilperoort 2018 EMBO Mol Med	2018	Schilperoort M, van Dam AD, Hoeke G, Shabalina IG, Okolo A, Hanyaloglu AC, Dib LH, Mol IM, Caengprasath N, Chan YW, Damak S, Miller AR, Coskun T, Shimpukade B, Ulven T, Kooijman S, Rensen PC, Christian M (2018) The GPR120 agonist TUG-891 promotes metabolic health by stimulating mitochondrial respiration in brown fat. EMBO Mol Med 10:e8047.	ET	N	Isolated mitochondria	Mouse	Fat
Leckey 2018 FASEB J	2018	Leckey JJ, Hoffman NJ, Parr EB, Devlin BL, Trewin AJ, Stepto NK, Morton JP, Burke LM, Hawley JA (2018) High dietary fat intake increases fat oxidation and reduces skeletal muscle mitochondrial respiration in trained humans. FASEB J 32:2979-91.	LEAK OXPHOS ET	F N S CIV NS ROX	Permeabilized tissue	Human	Skeletal muscle
Boutoual 2018 Sci Rep	2018	Boutoual R, Meseguer S, Villarroya M, Martín-Hernández E, Errami M, Martín MA, Casado M, Armengod ME (2018) Defects in the mitochondrial-tRNA modification enzymes MTO1 and GTPBP3 promote different metabolic reprogramming through a HIF-PPARγ-UCP2-AMPK axis. Sci Rep 8:1163.	LEAK OXPHOS ET	F N S NS ROX	Permeabilized cells Intact cells	Human	Fibroblast
Smenes 2018 Interact Cardiovasc Thorac Surg	2018	Smenes BT, Bækkerud FH, Slagsvold KH, Hassel E, Wohlwend M, Pinho M, Høydal M, Wisløff U, Rognmo Ø, Wahba A (2018) Acute exercise is not cardioprotective and may induce apoptotic signalling in heart surgery: a randomized controlled trial. Interact Cardiovasc Thorac Surg 27:95-101.	LEAK OXPHOS ET	F N S CIV NS ROX	Permeabilized tissue	Human	Heart
Woodman 2018 FASEB J	2018	Woodman AG, Mah R, Keddie D, Noble RMN, Panahi S, Gragasin FS, Lemieux H, Bourque SL (2018) Prenatal iron deficiency causes sex-dependent mitochondrial dysfunction and oxidative stress in fetal rat kidneys and liver. FASEB J 32:3254-63.	LEAK OXPHOS ET	N S CIV NS ROX	Homogenate	Rat	Liver Kidney
Isohanni 2018 Neurogenetics	2018	Isohanni P, Carroll CJ, Jackson CB, Pohjanpelto M, Lönnqvist T, Suomalainen A (2018) Defective mitochondrial ATPase due to rare mtDNA m.8969G>A mutation-causing lactic acidosis, intellectual disability, and poor growth. Neurogenetics 19:49-53.	OXPHOS ET	N S CIV NS	Permeabilized cells	Human	Skeletal muscle Blood cells Fibroblast
Silva 2018 Nat Cell Biol	2018	Silva J, Aivio S, Knobel PA, Bailey LJ, Casali A, Vinaixa M, Garcia-Cao I, Coyaud É, Jourdain AA, Pérez-Ferreros P, Rojas AM, Antolin-Fontes A, Samino-Gené S, Raught B, González-Reyes A, Ribas de Pouplana L, Doherty AJ, Yanes O, Stracker TH (2018) EXD2 governs germ stem cell homeostasis and lifespan by promoting mitoribosome integrity and translation. Nat Cell Biol 20:162-74.	OXPHOS ET	N S NS ROX	Permeabilized tissue		Islet cell;pancreas;thymus
Mavroudis 2018 Eur J Cardiothorac Surg	2018	Mavroudis CD, Karlsson M, Ko T, Hefti M, Gentile JI, Morgan RW, Plyler R, Mensah-Brown KG, Boorady TW, Melchior RW, Rosenthal TM, Shade BC, Schiavo KL, Nicolson SC, Spray TL, Sutton RM, Berg RA, Licht DJ, Gaynor JW, Kilbaugh TJ (2018) Cerebral mitochondrial dysfunction associated with deep hypothermic circulatory arrest in neonatal swine. Eur J Cardiothorac Surg 54:162-68.	LEAK ET OXPHOS	N S CIV NS ROX	Homogenate	Pig	Nervous system
Sahl 2018 Anal Biochem	2018	Sahl RE, Morville T, Kraunsøe R, Dela F, Helge JW, Larsen S (2018) Variation in mitochondrial respiratory capacity and myosin heavy chain composition in repeated muscle biopsies. Anal Biochem 556:119-24.	OXPHOS ET	N NS	Permeabilized cells Isolated mitochondria Intact cells	Human Mouse Saccharomyces cerevisiae	Skeletal muscle
Oemer 2018 Proc Nat Acad Sci U S A	2018	Oemer G, Lackner L, Muigg K, Krumschnabel G, Watschinger K, Sailer S, Lindner H, Gnaiger E, Wortmann SB, Werner ER, Zschocke J, Keller MA (2018) The molecular structural diversity of mitochondrial cardiolipins. Proc Nat Acad Sci U S A 115:4158-63.	LEAK ROUTINE OXPHOS ET	F N S Gp CIV NS ROX	Intact cells Permeabilized cells	Human	HeLa
Setz 2018 Hear Res	2018	Setz C, Benischke AS, Pinho Ferreira Bento AC, Brand Y, Levano S, Paech F, Leitmeyer K, Bodmer D (2018) Induction of mitophagy in the HEI-OC1 auditory cell line and activation of the Atg12/LC3 pathway in the organ of Corti. Hear Res 361:52-65.	OXPHOS ET	F N S NS ROX	Permeabilized cells	Mouse	Other cell lines
Robach 2018 Scand J Med Sci Sports	2018	Robach P, Hansen J, Pichon A, Meinild Lundby AK, Dandanell S, Slettaløkken Falch G, Hammarström D, Pesta DH, Siebenmann C, Keiser S, Kérivel P, Whist JE, Rønnestad BR, Lundby C (2018) Hypobaric live high-train low does not improve aerobic performance more than live low-train low in cross-country skiers. Scand J Med Sci Sports 28:1636-52.	OXPHOS ET	F N NS	Permeabilized tissue	Human	Skeletal muscle
Cardinale 2018 Physiol Rep	2018	Cardinale DA, Gejl KD, Ørtenblad N, Ekblom B, Blomstrand E, Larsen FJ (2018) Reliability of maximal mitochondrial oxidative phosphorylation in permeabilized fibers from the vastus lateralis employing high-resolution respirometry. Physiol Rep 6. doi: 10.14814/phy2.13611.	LEAK OXPHOS	F N	Permeabilized tissue	Human	Skeletal muscle
Christen 2018 Free Radic Biol Med	2018	Christen F, Desrosiers V, Dupont-Cyr BA, Vandenberg GW, Le François NR, Tardif JC, Dufresne F, Lamarre SG, Blier PU (2018) Thermal tolerance and thermal sensitivity of heart mitochondria: Mitochondrial integrity and ROS production. Free Radic Biol Med 116:11-8.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Fishes	Heart
Wu 2018 Adv Sci	2018	Wu S, Zhang A, Li S, Chatterjee S, Qi R, Segura-Ibarra V, Ferrari M, Gupte A, Blanco E, Hamilton DJ (2018) Polymer functionalization of isolated mitochondria for cellular transplantation and metabolic phenotype alteration. Adv Sci 1700530.	LEAK OXPHOS ET	N ROX	Isolated mitochondria	Mouse	Liver
Meinild Lundby 2018 Acta Physiol (Oxf)	2018	Meinild Lundby AK, Jacobs RA, Gehrig S, de Leur J, Hauser M, Bonne TC, Flück D, Dandanell S, Kirk N, Kaech A, Ziegler U, Larsen S, Lundby C (2018) Exercise training increases skeletal muscle mitochondrial volume density by enlargement of existing mitochondria and not de novo biogenesis. Acta Physiol (Oxf) 222, e12905.	OXPHOS LEAK ET	NS F N CIV	Permeabilized tissue	Human	Skeletal muscle
Jang 2018 J Med Toxicol	2018	Jang DH, Khatri UG, Mudan A, Love JS, Owiredu S, Eckmann DM (2018) Translational application of measuring mitochondrial functions in blood cells obtained from patients with acute poisoning. J Med Toxicol 14:144-51.	LEAK ROUTINE OXPHOS ET	N S Gp CIV NS ROX	Intact cells Permeabilized cells	Human	Blood cells
Treberg 2018 Comp Biochem Physiol B Biochem Mol Biol	2018	Treberg JR, Braun K, Zacharias P, Kroeker K (2018) Multidimensional mitochondrial energetics: Application to the study of electron leak and hydrogen peroxide metabolism. Comp Biochem Physiol B Biochem Mol Biol 224:121-28.	LEAK OXPHOS ET	N S NS	Isolated mitochondria	Mouse Rat	Skeletal muscle
Du 2018 Environ Sci Technol	2018	Du SNN, McCallum ES, Vaseghi-Shanjani M, Choi JA, Warriner TR, Balshine S, Scott GR (2018) Metabolic costs of exposure to wastewater effluent lead to compensatory adjustments in respiratory physiology in bluegill sunfish. Environ Sci Technol 52:801-11.	LEAK ET	N S NS	Isolated mitochondria	Fishes	Liver
Cardinale 2018 Acta Physiol (Oxf)	2018	Cardinale DA, Larsen FJ, Jensen-Urstad M, Rullman E, Søndergaard H, Morales-Alamo D, Ekblom B, Calbet JAL, Boushel R (2018) Muscle mass and inspired oxygen influence oxygen extraction at maximal exercise: Role of mitochondrial oxygen affinity. Acta Physiol (Oxf) 225:e13110.	OXPHOS	F N NS	Permeabilized tissue Isolated mitochondria	Human	Skeletal muscle
Weber 2018 Int J Mol Sci	2018	Weber A, Klocker H, Oberacher H, Gnaiger E, Neuwirt H, Sampson N, Eder IE (2018) Succinate accumulation is associated with a shift of mitochondrial respiratory control and HIF-1α upregulation in PTEN negative prostate cancer cells. Int J Mol Sci 19:2129.	ROUTINE OXPHOS ET	F N S NS Other combinations ROX	Intact cells Permeabilized cells	Human	Genital
Silaidos 2018 Biol Sex Differ	2018	Silaidos C, Pilatus U, Grewal R, Matura S, Lienerth B, Pantel J, Eckert GP (2018) Sex-associated differences in mitochondrial function in human peripheral blood mononuclear cells (PBMCs) and brain. Biol Sex Differ 9:34.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells Intact cells	Human	Nervous system Blood cells
Goswami 2018 Biophys J	2018	Goswami I, Perry JB, Allen ME, Brown DA, von Spakovsky MR, Verbridge SS (2018) Influence of pulsed electric fields and mitochondria-cytoskeleton interactions on cell respiration. Biophys J 114:2951-64.	OXPHOS ET	N	Intact cells	Mouse	Other cell lines
Kriel 2018 Sci Rep	2018	Kriel J, Mueller-Nedebock K, Maarman G, Mbizana S, Ojuka E, Klumperman B, Loos B (2018) Coordinated autophagy modulation overcomes glioblastoma chemoresistance through disruption of mitochondrial bioenergetics. Sci Rep 8:10348.	LEAK OXPHOS ET ROUTINE	N ROX	Permeabilized cells	Human	Nervous system Other cell lines
Remor 2018 Mol Neurobiol	2018	Remor AP, da Silva RA, de Matos FJ, Glaser V, de Paula Martins R, Ghisoni K, da Luz Scheffer D, Andia DC, Portinho D, de Souza AP, de Oliveira PA, Prediger RD, Torres AI, Linhares RMM, Walz R, Ronsoni MF, Hohl A, Rafacho A, Aguiar AS Jr, De Paul AL, Latini A (2018) Chronic metabolic derangement-induced cognitive deficits and neurotoxicity are associated with REST inactivation. Mol Neurobiol 56:1539-57.	LEAK OXPHOS	N	Intact cells	Rat	Nervous system
Jelenik 2018 Mol Metab	2018	Jelenik T, Dille M, Müller-Lühlhoff S, Kabra DG, Zhou Z, Binsch C, Hartwig S, Lehr S, Chadt A, Peters EMJ, Kruse J, Roden M, Al-Hasani H, Castañeda TR (2018) FGF21 regulates insulin sensitivity following long-term chronic stress. Mol Metab 16:126-38.	LEAK OXPHOS ET	F N NS	Permeabilized tissue	Mouse	Skeletal muscle
Boeck 2018 Sci Rep	2018	Boeck C, Salinas-Manrique J, Calzia E, Radermacher P, von Arnim CAF, Dietrich DE, Kolassa IT, Karabatsiakis A (2018) Targeting the association between telomere length and immunocellular bioenergetics in female patients with Major Depressive Disorder. Sci Rep 8:9419.	LEAK ROUTINE ET	N ROX	Intact cells	Human	Blood cells
Logan 2018 Thesis	2018	Logan C (2018) Nitrate and nitrite differentially affect respiration in zebrafish during exercise. Honors Baccalaureate of Science in Nutrition p44.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Zebrafish	Skeletal muscle
Juarez-Flores 2018 J Transl Med	2018	Juárez-Flores DL, González-Casacuberta I, Ezquerra M, Bañó M, Carmona-Pontaque F, Catalán-García M, Guitart-Mampel M, Rivero JJ, Tobias E, Milisenda JC, Tolosa E, Marti MJ, Fernández-Santiago R, Cardellach F, Morén C, Garrabou G (2018) Exhaustion of mitochondrial and autophagic reserve may contribute to the development of LRRK2^G2019S -Parkinson's disease. J Transl Med 16:160.		N	Permeabilized cells	Human	Fibroblast
Baaten 2018 Haematologica	2018	Baaten CCFMJ, Moenen FCJI, Henskens YMC, Swieringa F, Wetzels RJH, van Oerle R, Heijnen HFG, Ten Cate H, Holloway GP, Beckers EAM, Heemskerk JWM, van der Meijden PEJ (2018) Impaired mitochondrial activity explains platelet dysfunction in thrombocytopenic cancer patients undergoing chemotherapy. Haematologica 103:1557-67.	OXPHOS	N NS	Intact cells	Human	Blood cells Platelet
Rundle 2018 Environ Sci Technol	2018	Rundle K, Sharaf M, Stevens D, Kamunde C, Van Den Heuvel MR (2018) Oil sands-derived naphthenic acids are oxidative uncouplers and impair electron transport in isolated mitochondria. Environ Sci Technol 52:10803-11.	LEAK OXPHOS ET	N ROX	Isolated mitochondria	Fishes	Liver
Kauppila 2018 Nucleic Acids Res	2018	Kauppila JHK, Bonekamp NA, Mourier A, Isokallio MA, Just A, Kauppila TES, Stewart JB, Larsson NG (2018) Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice. Nucleic Acids Res 46:6642-69.	LEAK OXPHOS ET	N S NS	Isolated mitochondria	Mouse
Khamoui 2018 J Dev Orig Health Dis	2018	Khamoui AV, Desai M, Ross MG, Rossiter HB (2018) Sex-specific effects of maternal and postweaning high-fat diet on skeletal muscle mitochondrial respiration. J Dev Orig Health Dis 16:1-8.	LEAK OXPHOS ET	N NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Ferri 2018 Eur J Appl Physiol	2018	Ferri A, Panariti A, Miserocchi G, Rocchetti M, Buoli Comani G, Rivolta I, Bishop DJ (2018) Tissue specificity of mitochondrial adaptations in rats after 4 weeks of normobaric hypoxia. Eur J Appl Physiol 118:1641-52.	LEAK OXPHOS	N	Permeabilized tissue	Rat	Heart Skeletal muscle
Wen 2018 PLOS Pathog	2018	Wen JJ, Yin YW, Garg NJ (2018) PARP1 depletion improves mitochondrial and heart function in Chagas disease: Effects on POLG dependent mtDNA maintenance. PLOS Pathog 14:e1007065.	OXPHOS	N S NS	Permeabilized tissue	Mouse	Heart Other cell lines
Bricambert 2018 Nat Commun	2018	Bricambert J, Alves-Guerra MC, Esteves P, Prip-Buus C, Bertrand-Michel J, Guillou H, Chang CJ, Vander Wal MN, Canonne-Hergaux F, Mathurin P, Raverdy V, Pattou F, Girard J, Postic C, Dentin R (2018) The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity. Nat Commun 9:2092.	LEAK OXPHOS ET	N S	Homogenate	Mouse	Liver
Marini 2018 Proc Natl Acad Sci U S A	2018	Marini A, Rotblat B, Sbarrato T, Niklison-Chirou MV, Knight JRP, Dudek K, Jones C, Bushell M, Knight RA, Amelio I, Willis AE, Melino G (2018) TAp73 contributes to the oxidative stress response by regulating protein synthesis. Proc Natl Acad Sci U S A 115:6219-24.	OXPHOS	N	Homogenate	Human	Kidney Lung;gill HEK
Kamunde 2018 Free Radic Biol Med	2018	Kamunde C, Sharaf M, MacDonald N (2018) H₂O₂ metabolism in liver and heart mitochondria: Low emitting-high scavenging and high emitting-low scavenging systems. Free Radic Biol Med 124:135-48.	LEAK	N ROX	Isolated mitochondria	Fishes	Heart Liver
Carter 2018 J Physiol	2018	Carter HN, Kim Y, Erlich AT, Zarrin-Khat D, Hood DA (2018) Autophagy and mitophagy flux in young and aged skeletal muscle following chronic contractile activity. J Physiol 596:3567-84.	LEAK OXPHOS	N NS	Permeabilized tissue	Rat	Skeletal muscle
Temelie 2018 Oxid Med Cell Longev	2018	Temelie M, Savu DI, Moisoi N (2018) Intracellular and intercellular signalling mechanisms following DNA damage are modulated by PINK1. Oxid Med Cell Longev 1391387.	OXPHOS ET	N NS	Permeabilized cells	Human Mouse	Nervous system Other cell lines Fibroblast
Stein 2018 Cell Rep	2018	Stein CS, Jadiya P, Zhang X, McLendon JM, Abouassaly GM, Witmer NH, Anderson EJ, Elrod JW, Boudreau RL (2018) Mitoregulin: A lncRNA-encoded microprotein that supports mitochondrial supercomplexes and respiratory efficiency. Cell Rep 23:3710-20.	LEAK OXPHOS	F N	Permeabilized tissue	Human	Heart Skeletal muscle
Chou 2018 Int J Cardiol	2018	Chou CH, Fu TC, Tsai HH, Hsu CC, Wang CH, Wang JS (2018) High-intensity interval training enhances mitochondrial bioenergetics of platelets in patients with heart failure. Int J Cardiol 274:214-20.	LEAK ROUTINE OXPHOS ET	F N S NS ROX	Intact cells Permeabilized cells	Human	Platelet Blood cells
Hafen 2018 J Appl Physiol (1985)	2018	Hafen PS, Preece CN, Sorensen JR, Hancock CR, Hyldahl RD (2018) Repeated exposure to heat stress induces mitochondrial adaptation in human skeletal muscle. J Appl Physiol (1985) 125:1447-55.	OXPHOS ET	N S NS ROX	Permeabilized tissue	Human	Skeletal muscle
Gam 2018 Acta Diabetol	2018	Gam CMBF, Mortensen OH, Larsen LH, Poulsen SS, Qvortrup K, Mathiesen ER, Damm P, Quistorff B (2018) Diabetes, myometrium, and mitochondria in pregnant women at term. Acta Diabetol 55:999-1010.	LEAK OXPHOS	F N S NS	Isolated mitochondria	Human	Genital
Barca 2018 Hum Mol Genet	2018	Barca E, Ganetzky RD, Potluri P, Juanola-Falgarona M, Gai X, Li D, Jalas C, Hirsch Y, Emmanuele V, Tadesse S, Ziosi M, Akman HO, Chung WK, Tanji K, McCormick E, Place E, Consugar M, Pierce EA, Hakonarson H, Wallace DC, Hirano M, Falk MJ (2018) USMG5 Ashkenazi Jewish founder mutation impairs mitochondrial complex V dimerization and ATP synthesis. Hum Mol Genet 27:3305-12.	LEAK ROUTINE OXPHOS ET	F N S DQ NS ROX	Permeabilized cells Intact cells	Human	Fibroblast
Van der Pluijm 2018 Cardiovasc Res	2018	van der Pluijm I, Burger J, van Heijningen PM, IJpma A, van Vliet N, Milanese C, Schoonderwoerd K, Sluiter W, Ringuette LJ, Dekkers DHW, Que I, Kaijzel EL, Te Riet L, MacFarlane E, Das D, van der Linden R, Vermeij M, Demmers JA, Mastroberardino PG, Davis EC, Yanagisawa H, Dietz H, Kanaar R, Essers J (2018) Decreased mitochondrial respiration in aneurysmal aortas of Fibulin-4 mutant mice is linked to PGC1A regulation. Cardiovasc Res 114:1776-93.	OXPHOS	N S NS ROX	Homogenate	Mouse	Skeletal muscle
Rodrigues 2018 Sci Rep	2018	Rodrigues APC, Camargo AF, Andjelkovic A, Jacobs HT, Oliveira MT (2018) Developmental arrest in Drosophila melanogaster caused by mitochondrial DNA replication defects cannot be rescued by the alternative oxidase. Sci Rep 8:10882.	OXPHOS	N CIV ROX	Homogenate Oxidase;biochemical oxidation	Drosophila
Paech 2018a Toxicology	2018	Paech F, Mingard C, Grünig D, Abegg VF, Bouitbir J, Krähenbühl S (2018) Mechanisms of mitochondrial toxicity of the kinase inhibitors ponatinib, regorafenib and sorafenib in human hepatic HepG2 cells. Toxicology 395:34-44.	LEAK OXPHOS ET	N S DQ CIV ROX	Permeabilized cells Isolated mitochondria	Human Mouse	Liver Other cell lines
Paech 2018b Toxicology	2018	Paech F, Abegg VF, Duthaler U, Terracciano L, Bouitbir J, Krähenbühl S (2018) Sunitinib induces hepatocyte mitochondrial damage and apoptosis in mice. Toxicology 409:13-23.	LEAK OXPHOS ET	N S DQ CIV ROX NS	Isolated mitochondria	Mouse	Liver
Cruz 2018 Chem Biol Interact	2018	Cruz LC, Ecker A, Rodrigues NR, Martins IK, Posser T, Maciel FE, Vargas MA, Barbosa NV, Franco JL (2018) Honey protects against wings posture error and molecular changes related to mitochondrial pathways induced by hypoxia/reoxygenation in adult Drosophila melanogaster. Chem Biol Interact 291:245-52.	LEAK OXPHOS ET	N NS	Isolated mitochondria	Drosophila
Seite 2018 Sci Rep	2018	Seite S, Mourier A, Camougrand N, Salin B, Figueiredo-Silva AC, Fontagne-Dicharry S, Panserat S, Seiliez I (2018) Dietary methionine deficiency affects oxidative status, mitochondrial integrity and mitophagy in the liver of rainbow trout (Oncorhynchus mykiss). Sci Rep 8:10151.		N S CIV NS ROX	Homogenate	Fishes	Liver
Scott 2018 Integr Comp Biol	2018	Scott GR, Guo KH, Dawson NJ (2018) The mitochondrial basis for adaptive variation in aerobic performance in high-altitude deer mice. Integr Comp Biol 58:506-18. https://doi.org/10.1093/icb/icy056	OXPHOS ET	N S CIV NS	Permeabilized tissue Isolated mitochondria	Mouse	Heart Skeletal muscle
Casal 2018 J Anim Sci	2018	Casal A, Garcia-Roche M, Navajas EA, Cassina A, Carriquiry M (2018) Hepatic mitochondrial function in Hereford steers with divergent residual feed intake phenotypes. J Anim Sci 96:4431-43.	LEAK OXPHOS ET	N S ROX	Intact cells	Bovines	Liver
Salin 2018 Integr Comp Biol	2018	Salin K, Villasevil EM, Anderson GJ, Selman C, Chinopoulos C, Metcalfe NB (2018) The RCR and ATP/O indices can give contradictory messages about mitochondrial efficiency. Integr Comp Biol 58:486-94.	LEAK OXPHOS	N S NS ROX	Homogenate	Fishes	Liver
Wefers 2018 Proc Natl Acad Sci U S A	2018	Wefers J, van Moorsel D, Hansen J, Connell NJ, Havekes B, Hoeks J, van Marken Lichtenbelt WD, Duez H, Phielix E, Kalsbeek A, Boekschoten MV, Hooiveld GJ, Hesselink MKC, Kersten S, Staels B, Scheer FAJL, Schrauwen P (2018) Circadian misalignment induces fatty acid metabolism gene profiles and compromises insulin sensitivity in human skeletal muscle. Proc Natl Acad Sci U S A 115:7789-94.	OXPHOS ET	F N	Intact cells	Human	Skeletal muscle
Klepinin 2018 J Bioenerg Biomembr	2018	Klepinin A, Ounpuu L, Mado K, Truu L, Chekulayev V, Puurand M, Shevchuk I, Tepp K, Planken A, Kaambre T (2018) The complexity of mitochondrial outer membrane permeability and VDAC regulation by associated proteins. J Bioenerg Biomembr 50:339-54.	LEAK OXPHOS ET	N S NS ROX	Permeabilized cells	Mouse	Heart Neuroblastoma
Cecatto 2018 J Cell Biochem	2018	Cecatto C, Wajner A, Vargas CR, Wajner SM, Amaral AU, Wajner M (2018) High vulnerability of the heart and liver to 3-hydroxypalmitic acid-induced disruption of mitochondrial functions in intact cell systems. J Cell Biochem 119:7678-86.	LEAK OXPHOS ET	N	Permeabilized cells Permeabilized tissue	Rat	Heart Nervous system Liver
Lu 2018 Cell Rep	2018	Lu Z, Cui Y, Wei X, Gao P, Zhang H, Wei X, Li Q, Sun F, Yan Z, Zheng H, Yang G, Liu D, Zhu Z (2018) Deficiency of PKD2L1 (TRPP3) exacerbates pathological cardiac hypertrophy by augmenting NCX1-mediated mitochondrial calcium overload. Cell Rep 24:1639-52.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Mouse	Heart
Vinel 2018 Nat Med	2018	Vinel C, Lukjanenko L, Batut A, Deleruyelle S, Pradere JP, Le Gonidec S, Dortignac A, Geoffre N, Pereira O, Karaz S, Lee U, Camus M, Chaoui K, Mouisel E, Bigot A, Mouly V, Vigneau M, Pagano AF, Chopard A, Pillard F, Guyonnet S, Cesari M, Burlet-Schiltz O, Pahor M, Feige JN, Vellas B, Valet P, Dray C (2018) The exerkine apelin reverses age-associated sarcopenia. Nat Med 24:1360-71.	OXPHOS	N S	Permeabilized tissue	Mouse	Skeletal muscle
Pileggi 2018 Free Radic Biol Med	2018	Pileggi CA, Hedges CP, D'Souza RF, Durainayagam BR, Markworth JF, Hickey AJR, Mitchell CJ, Cameron-Smith D (2018) Exercise recovery increases skeletal muscle H₂O₂ emission and mitochondrial respiratory capacity following two-weeks of limb immobilization. Free Radic Biol Med 124:241-8.	LEAK OXPHOS ET	N NS ROX	Permeabilized tissue	Human	Skeletal muscle
Ounpuu 2018 Biochem Cell Biol	2018	Ounpuu L, Truu L, Shevchuk I, Chekulayev V, Klepinin A, Koit A, Tepp K, Puurand M, Rebane-Klemm E, Käämbre T (2018) Comparative analysis of the bioenergetics of human adenocarcinoma Caco-2 cell line and postoperative tissue samples from colorectal cancer patients. Biochem Cell Biol [Epub ahead of print].	LEAK OXPHOS	N S CIV ROX	Permeabilized cells	Human	Endothelial;epithelial;mesothelial cell Other cell lines
Cree-Green 2018 Diabetes	2018	Cree-Green M, Scalzo RL, Harrall K, Newcomer BR, Schauer IE, Huebschmann AG, McMillin S, Brown MS, Orlicky D, Knaub L, Nadeau KJ, Mcclatchey PM, Bauer TA, Regensteiner JG, Reusch JEB (2018) Supplemental oxygen improves in-vivo mitochondrial oxidative phosphorylation flux in sedentary obese adults with type 2 diabetes. Diabetes 67:1369-79.	LEAK OXPHOS ET	F N NS	Permeabilized tissue	Human	Skeletal muscle
Vatner 2018 Aging Cell	2018	Vatner DE, Zhang J, Oydanich M, Guers J, Katsyuba E, Yan L, Sinclair D, Auwerx J, Vatner SF (2018) Enhanced longevity and metabolism by brown adipose tissue with disruption of the regulator of G protein signaling 14. Aging Cell 17:e12751.	LEAK OXPHOS	N S NS	Intact cells	Mouse	Fat
Chung 2018 J Exp Biol	2018	Chung DJ, Sparagna GC, Chicco AJ, Schulte PM (2018) Patterns of mitochondrial membrane remodeling parallel functional adaptations to thermal stress. J Exp Biol 221. pii: jeb174458.	LEAK OXPHOS ET	F N S CIV NS ROX	Isolated mitochondria	Fishes	Liver
Rodrigues 2018 Free Radic Biol Med	2018	Rodrigues NR, Macedo GE, Martins IK, Gomes KK, de Carvalho NR, Posser T, Franco JL (2018) Short-term sleep deprivation with exposure to nocturnal light alters mitochondrial bioenergetics in Drosophila. Free Radic Biol Med 120:395-406.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Drosophila
Martinez 2018 Arch Biochem Biophys	2018	Martínez JH, Fuentes F, Vanasco V, Alvarez S, Alaimo A, Cassina A, Coluccio Leskow F, Velazquez F (2018) Alpha-synuclein mitochondrial interaction leads to irreversible translocation and complex I impairment. Arch Biochem Biophys 651:1-12.	LEAK OXPHOS ET	N S ROX	Isolated mitochondria	Rat	Nervous system
Kolb 2018 J Am Soc Nephrol	2018	Kolb AL, Corridon PR, Zhang S, Xu W, Witzmann FA, Collett JA, Rhodes GJ, Winfree S, Bready D, Pfeffenberger ZJ, Pomerantz JM, Hato T, Nagami GT, Molitoris BA, Basile DP, Atkinson SJ, Bacallao RL (2018) Exogenous gene transmission of isocitrate dehydrogenase 2 mimics ischemic preconditioning protection. J Am Soc Nephrol 29:1154-64.	OXPHOS	N NS	Isolated mitochondria		Kidney
Chung 2018 Integr Comp Biol	2018	Chung DJ, Healy TM, McKenzie JL, Chicco AJ, Sparagna GC, Schulte PM (2018) Mitochondria, temperature, and the pace of life. Integr Comp Biol 58:578-90.	OXPHOS	N	Permeabilized tissue Isolated mitochondria	Fishes	Heart Nervous system Liver
Dejos 2018 Sci Rep	2018	Dejos C, Kuny S, Han WH, Capel H, Lemieux H, Sauvé Y (2018) Photoreceptor-induced RPE phagolysosomal maturation defects in Stargardt-like Maculopathy (STGD3). Sci Rep 8:5944.	OXPHOS	N S CIV NS ROX	Homogenate	Mouse	Endothelial;epithelial;mesothelial cell
Monaco 2018b Diabetologia	2018	Monaco CMF, Hughes MC, Ramos SV, Varah NE, Lamberz C, Rahman FA, McGlory C, Tarnopolsky MA, Krause MP, Laham R, Hawke TJ, Perry CGR (2018) Altered mitochondrial bioenergetics and ultrastructure in the skeletal muscle of young adults with type 1 diabetes. Diabetologia 61:1411-23.	OXPHOS	N S Gp NS ROX	Permeabilized tissue	Human	Skeletal muscle
Toledo 2018 Obesity (Silver Spring)	2018	Toledo FGS, Dubé JJ, Goodpaster BH, Stefanovic-Racic M, Coen PM, DeLany JP (2018) Mitochondrial respiration is associated with lower energy expenditure and lower aerobic capacity in African American women. Obesity (Silver Spring) 26:903-9.	LEAK OXPHOS ET	F N NS	Permeabilized tissue	Human	Skeletal muscle
Komlodi 2018 Methods Mol Biol	2018	Komlodi T, Sobotka O, Krumschnabel G, Bezuidenhout N, Hiller E, Doerrier C, Gnaiger E (2018) Comparison of mitochondrial incubation media for measurement of respiration and hydrogen peroxide production. Methods Mol Biol 1782:137-55.	LEAK OXPHOS ET	F N S CIV NS ROX	Permeabilized cells Permeabilized tissue	Human Mouse	Skeletal muscle HEK
Tillmans 2018 Thesis	2018	Tillmans F (2018) Effect of normobaric hypoxia on leukemic vell lines in vitro. Dissertation p92.	LEAK ROUTINE ET	N S NS ROX	Intact cells Permeabilized cells	Human	Other cell lines Lymphocyte
Flis 2018 Oxid Med Cell Longev	2018	Flis DJ, Dzik K, Kaczor JJ, Halon-Golabek M, Antosiewicz J, Wieckowski MR, Ziolkowski W (2018) Swim training modulates skeletal muscle energy metabolism, oxidative stress, and mitochondrial cholesterol content in amyotrophic lateral sclerosis mice. Oxid Med Cell Longev 5940748.	LEAK OXPHOS	N	Isolated mitochondria	Mouse	Skeletal muscle
Ravasz 2018 Biochim Biophys Acta	2018	Ravasz D, Kacso G, Fodor V, Horvath K, Adam-Vizi V, Chinopoulos C (2018) Reduction of 2-methoxy-1,4-naphtoquinone by mitochondrially-localized Nqo1 yielding NAD⁺ supports substrate-level phosphorylation during respiratory inhibition. Biochim Biophys Acta 1859:909-24.	LEAK OXPHOS	F N DQ	Isolated mitochondria	Mouse	Liver
Yang 2018 Cell Death Dis	2018	Yang F, Wu R, Jiang Z, Chen J, Nan J, Su S, Zhang N, Wang C, Zhao J, Ni C, Wang Y, Hu W, Zeng Z, Zhu K, Liu X, Hu X, Zhu W, Yu H, Huang J, Wang J (2018) Leptin increases mitochondrial OPA1 via GSK3-mediated OMA1 ubiquitination to enhance therapeutic effects of mesenchymal stem cell transplantation. Cell Death Dis 9:556.		N S CIV NS ROX	Intact cells	Mouse
Kong 2018 Proteomics	2018	Kong D, Tian X, Li Y*, Zhang S, Cheng Y, Huo L, Ma H, Yang Z, Ren L, Zhang M, Zhang W (2018) Revealing the inhibitory effect of ginseng on mitochondrial respiration through synaptosomal proteomics. Proteomics 18:e1700354.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Homogenate	Rat	Nervous system
Kappler 2018 Thesis	2018	Kappler L (2018) Method development for valid high‐resolution profiling of mitochondria and Omics investigation of mitochondrial adaptions to excess energy intake and physical exercise. Dissertation p181.	LEAK OXPHOS ET	F N S CIV NS ROX	Permeabilized cells Homogenate Isolated mitochondria	Human Mouse	Skeletal muscle Liver Other cell lines
Robb 2018 J Biol Chem	2018	Robb EL, Hall AR, Prime TA, Eaton S, Szibor M, Viscomi C, James AM, Murphy MP (2018) Control of mitochondrial superoxide production by reverse electron transport at complex I. J Biol Chem 293:9869-79. https://doi.org/10.1074/jbc.RA118.003647	ET	N S ROX	Isolated mitochondria	Rat	Heart
Bytautiene 2018 J Dev Orig Health Dis	2018	Bytautiene Prewit E, Porter C, La Rosa M, Bhattarai N, Yin H, Gamble P, Kechichian T, Sidossis LS (2018) Adipose tissue uncoupling protein 1 levels and function are increased in a mouse model of developmental obesity induced by maternal exposure to high-fat diet. J Dev Orig Health Dis 9:401-8.	LEAK	F N	Permeabilized tissue	Mouse	Fat
Tarpey 2018 Skelet Muscle	2018	Tarpey MD, Amorese AJ, Balestrieri NP, Ryan TE, Schmidt CA, McClung JM, Spangenburg EE (2018) Characterization and utilization of the flexor digitorum brevis for assessing skeletal muscle function. Skelet Muscle 8:14.	OXPHOS	N S CIV NS ROX		Mouse	Skeletal muscle
Mkrtchyan 2018 Biochim Biophys Acta	2018	Mkrtchyan GV, Üçal M, Müllebner A, Dumitrescu S, Kames M, Moldzio R, Molcanyi M, Schaefer S, Weidinger A, Schaefer U, Hescheler J, Duvigneau JC, Redl H, Bunik VI, Kozlov AV (2018) Thiamine preserves mitochondrial function in a rat model of traumatic brain injury, preventing inactivation of the 2-oxoglutarate dehydrogenase complex. Biochim Biophys Acta 1859:925-31.	OXPHOS	N S	Homogenate	Rat	Nervous system
Djafarzadeh 2017b J Vis Exp	2017	Djafarzadeh S, Jakob SM (2017) Isolation of intact mitochondria from skeletal muscle by differential centrifugation for High-Resolution Respirometry measurements. J Vis Exp doi: 10.3791/55251.	LEAK OXPHOS	N S CIV NS	Isolated mitochondria		Skeletal muscle
Holland 2017 Placenta	2017	Holland OJ, Hickey AJR, Alvsaker A, Moran S, Hedges C, Chamley LW, Perkins AV (2017) Changes in mitochondrial respiration in the human placenta over gestation. Placenta 57:102-12.	LEAK ROUTINE OXPHOS	F N CIV NS ROX	Permeabilized cells Intact cells		Genital
Linden 2016 Am J Physiol Gastrointest Liver Physiol	2017	Linden MA, Fletcher JA, Meers GM, Thyfault JP, Laughlin MH, Rector RS (2017) A return to ad libitum feeding following caloric restriction promotes hepatic steatosis in hyperphagic OLETF rats. Am J Physiol Gastrointest Liver Physiol 311:G387-95.	OXPHOS ET LEAK	N NS	Isolated mitochondria	Rat	Liver
Van Schaardenburgh 2017 J Transl Med	2017	van Schaardenburgh M, Wohlwend M, Rognmo Ø, Mattsson EJR (2017) Exercise in claudicants increase or decrease walking ability and the response relates to mitochondrial function. J Transl Med 15:130.	LEAK OXPHOS ET	F N S NS ROX	Permeabilized tissue	Human	Skeletal muscle
Pecinova 2017 Oxid Med Cell Longev	2017	Pecinova A, Drahota Z, Kovalcikova J, Kovarova N, Pecina P, Alan L, Zima M, Houstek J, Mracek T (2017) Pleiotropic effects of biguanides on mitochondrial reactive oxygen species production. Oxid Med Cell Longev 7038603.	LEAK OXPHOS ET	N S Gp NS	Isolated mitochondria	Rat	Fat
Ereminas 2017 Biomed Pharmacother	2017	Ereminas G, Majiene D, Sidlauskas K, Jakstas V, Ivanauskas L, Vaitiekaitis G, Liobikas J (2017) Neuroprotective properties of anthocyanidin glycosides against H₂O₂-induced glial cell death are modulated by their different stability and antioxidant activity in vitro. Biomed Pharmacother 94:188-96.	OXPHOS	N	Permeabilized cells	Rat	Nervous system
Pereira 2017 EMBO J	2017	Pereira RO, Tadinada SM, Zasadny FM, Oliveira KJ, Pires KMP, Olvera A, Jeffers J, Souvenir R, Mcglauflin R, Seei A, Funari T, Sesaki H, Potthoff MJ, Adams CM, Anderson EJ, Abel ED (2017) OPA1 deficiency promotes secretion of FGF21 from muscle that prevents obesity and insulin resistance. EMBO J 36:2126-45.	OXPHOS	N NS	Permeabilized tissue	Mouse	Skeletal muscle
Merz 2017 Intensive Care Med Exp	2017	Merz T, Vogt JA, Wachter U, Calzia E, Szabo C, Wang R, Radermacher P, McCook O (2017) Impact of hyperglycemia on cystathionine-γ-lyase expression during resuscitated murine septic shock. Intensive Care Med Exp 5:30.	LEAK OXPHOS ET	F N S NS ROX	Homogenate	Mouse	Liver
Zhang 2017 J Am Heart Assoc	2017	Zhang X, Zhang Z, Zhao Y, Jiang N, Qiu J, Yang Y, Li J, Liang X, Wang X, Tse G, Li G, Liu T (2017) Alogliptin, a dipeptidyl peptidase-4 inhibitor, alleviates atrial remodeling and improves mitochondrial function and biogenesis in diabetic rabbits. J Am Heart Assoc 6:e005945.	LEAK OXPHOS	N	Isolated mitochondria	Rabbit	Heart
Han 2017 Invest Ophthalmol Vis Sci	2017	Han WH, Gotzmann J, Kuny S, Huang H, Chan CB, Lemieux H, Sauvé Y (2017) Modifications in retinal mitochondrial respiration precede type 2 diabetes and protracted microvascular retinopathy. Invest Ophthalmol Vis Sci 58:3826-39.	LEAK OXPHOS	N S CIV NS ROX	Homogenate	Rat	Nervous system
Vigueira 2017 Exp Physiol	2017	Vigueira PA, McCommis KS, Hodges WT, Schweitzer GG, Cole SL, Oonthonpan L, Taylor EB, McDonald WG, Kletzien RF, Colca JR, Finck BN (2017) The beneficial metabolic effects of insulin sensitizers are not attenuated by mitochondrial pyruvate carrier 2 hypomorphism. Exp Physiol 102:985-99.	OXPHOS LEAK	N	Permeabilized cells	Human	Kidney HEK
Ounpuu 2017 Biochim Biophys Acta	2017	Ounpuu L, Klepinin A, Pook M, Teino I, Peet N, Paju K, Tepp K, Chekulayev V, Shevchuk I, Koks S, Maimets T, Kaambre T (2017) 2102Ep embryonal carcinoma cells have compromised respiration and shifted bioenergetic profile distinct from H9 human embryonic stem cells. Biochim Biophys Acta 1861:2146-54.	LEAK ROUTINE OXPHOS ET	N S NS ROX CIV	Permeabilized cells Intact cells	Human	Stem cells
Rodrigues-Silva 2017 J Neurooncol	2017	Rodrigues-Silva E, Siqueira-Santos ES, Ruas JS, Ignarro RS, Figueira TR, Rogério F, Castilho RF (2017) Evaluation of mitochondrial respiratory function in highly glycolytic glioma cells reveals low ADP phosphorylation in relation to oxidative capacity. 10.1007/s11060-017-2482-0	LEAK ROUTINE OXPHOS ET	N ROX	Permeabilized cells Isolated mitochondria Intact cells	Rat	Nervous system
Svensson 2017 Acta Physiol (Oxf)	2017	Svensson K, LaBarge SA, Martins VF, Schenk S (2017) Temporal overexpression of SIRT1 in skeletal muscle of adult mice does not improve insulin sensitivity or markers of mitochondrial biogenesis. Acta Physiol (Oxf) 221:193-203.	OXPHOS ET LEAK	F N S NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Zhou 2017 Biochim Biophys Acta	2017	Zhou L, Wang W, Hoppel C, Liu J, Zhu X (2017) Parkinson's disease-associated pathogenic VPS35 mutation causes complex I deficits. Biochim Biophys Acta 1863:2791-5.	OXPHOS ET	N S NS ROX	Isolated mitochondria	Human	Fibroblast
Trewin 2017 PLOS ONE	2017	Trewin AJ, Levinger I, Parker L, Shaw CS, Serpiello FR, Anderson MJ, McConell GK, Hare DL, Stepto NK (2017) Acute exercise alters skeletal muscle mitochondrial respiration and H₂O₂ emission in response to hyperinsulinemic-euglycemic clamp in middle-aged obese men. PLOS ONE 12:e0188421.	LEAK OXPHOS ET	F N NS ROX	Permeabilized tissue	Human	Skeletal muscle
Paech 2017 Arch Toxicol	2017	Paech F, Messner S, Spickermann J, Wind M, Schmitt-Hoffmann AH, Witschi AT, Howell BA, Church RJ, Woodhead J, Engelhardt M, Krähenbühl S, Maurer M (2017) Mechanisms of hepatotoxicity associated with the monocyclic β-lactam antibiotic BAL30072. Arch Toxicol 91:3647-62.	LEAK OXPHOS ET	N S DQ CIV ROX	Permeabilized cells	Human	Liver Other cell lines
Kake 2017 J Therm Biol	2017	Kake Guena SA, Touisse K, Warren BE, Scott KY, Dufresne F, Blier PU, Lemieux H (2017) Temperature-related differences in mitochondrial function among clones of the cladoceran Daphnia pulex. J Therm Biol 69:23-31.	LEAK OXPHOS	N CIV NS S ROX	Permeabilized tissue	Crustaceans
Fink 2017 Am J Physiol Cell Physiol	2017	Fink BD, Bai F, Yu L, Sivitz WI (2017) Regulation of ATP production: dependence on calcium concentration and respiratory state. Am J Physiol Cell Physiol 313:C146-53.	LEAK OXPHOS	N S	Isolated mitochondria	Mouse	Skeletal muscle
Rekuviene 2017 Neurosci Lett	2017	Rekuviene E, Ivanoviene L, Borutaite V, Morkuniene R (2017) Rotenone decreases ischemia-induced injury by inhibiting mitochondrial permeability transition in mature brains. Neurosci Lett 653:45-50.		N S NS	Isolated mitochondria	Rat	Nervous system
Thaher 2017 Neurochem Int	2017	Thaher O, Wolf C, Dey PN, Pouya A, Wüllner V, Tenzer S, Methner A (2017) The thiol switch C684 in Mitofusin-2 mediates redox-induced alterations of mitochondrial shape and respiration. Neurochem Int 117:167-73.	LEAK ROUTINE OXPHOS ET	N NS ROX	Intact cells Permeabilized cells	Mouse	Fibroblast
Buso 2017 Thesis	2017	Buso A (2017) Mitochondrial oxidative phosphorylation plasticity/adaptation triggered by disturbances and stresses and targeted by therapies. PhD Thesis p110.	LEAK OXPHOS ET	N S NS	Permeabilized tissue	Mouse	Skeletal muscle
Grassi 2017 J Appl Physiol (1985)	2017	Grassi B, Majerczak J, Bardi E, Buso A, Comelli M, Chlopicki S, Guzik M, Mavelli I, Nieckarz Z, Salvadego D, Tyrankiewicz U, Skórka T, Bottinelli R, Zoladz JA, Pellegrino MA (2017) Exercise training in Tgα_q*44 mice during the progression of chronic heart failure: cardiac vs. peripheral (soleus muscle) impairments to oxidative metabolism. J Appl Physiol (1985) 123:326-36.	LEAK OXPHOS ET	N NS S	Permeabilized tissue	Mouse	Skeletal muscle
Xiong 2017 J Am Heart Assoc	2017	Xiong S, Wang B, Lin S, Zhang H, Li Y, Wei X, Cui Y, Wei X, Lu Z, Gao P, Li L, Zhao Z, Liu D, Zhu Z (2017) Activation of transient receptor potential melastatin subtype 8 attenuates cold-induced hypertension through ameliorating vascular mitochondrial dysfunction. J Am Heart Assoc 6. pii: e005495.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells Intact cells	Mouse	Endothelial;epithelial;mesothelial cell
Volani 2017 Metallomics	2017	Volani C, Doerrier C, Demetz E, Haschka D, Paglia G, Lavdas AA, Gnaiger E, Weiss G (2017) Dietary iron loading negatively affects liver mitochondrial function. Metallomics 9:1634-44.	LEAK OXPHOS ET	N S NS ROX	Homogenate	Mouse	Liver
Zeidler 2017 J Biol Chem	2017	Zeidler JD, Fernandes-Siqueira LO, Carvalho AS, Cararo-Lopes E, Dias MH, Ketzer LA, Galina A, Da Poian AT (2017) Short-term starvation is a strategy to unravel the cellular capacity of oxidizing specific exogenous/endogenous substrates in mitochondria. J Biol Chem 292:14176-87.	LEAK ROUTINE ET	F N ROX	Intact cells	Mouse
Thomas 2017 Thesis	2017	Thomas NO (2017) Age-related decrease in resilience against acute redox cycling agents: critical role of declining GSH-dependent detoxification capacity. Dissertation p141.	LEAK OXPHOS ET	N NS ROX	Permeabilized cells Intact cells	Rat	Liver
Wang 2017 J Am Heart Assoc	2017	Wang B, Xiong S, Lin S, Xia W, Li Q, Zhao Z, Wei X, Lu Z, Wei X, Gao P, Liu D, Zhu Z (2017) Enhanced mitochondrial transient receptor potential channel, canonical type 3-mediated calcium handling in the vasculature from hypertensive rats. J Am Heart Assoc 6. pii: e005812.	ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells	Rat	Endothelial;epithelial;mesothelial cell
Da Silva 2017 Thesis	2017	da Silva LA (2017) Efeito do tratamento com N-acetilcisteína sobre dinâmica mitocondrial em modelo animal de isquemia crônica de membros inferiores. Dissertation p54.	OXPHOS	F N NS		Rat	Skeletal muscle

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