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Revision as of 17:44, 18 July 2017
MiPschool Obergurgl 2017
Obergurgl AT, 2017 Jul 23-30. 10th MiPschool 2017 MITOEAGLE and MITOEAGLE Workshop WG1-4. |
Mitochondrial Physiology Society (2017-07-23) MitoGlobal
Abstract: 2017 Jul 23-30, Obergurgl, AT.
Date, venue, organization
- 2017 July 23-30
- 2017 July 23-27 Training School jointly organized by the Mitochondrial Physiology Society and COST Action MITOEAGLE
- 2017 July 27-30 MITOEAGLE Workshop: WG1-4
- University Centre Obergurgl, Tyrol, Austria
- Registration updated deadline: 2017 Jun 15
Lecturers
Programme
- Programme development: For the MiPsummer school in Obergurgl the last week of July, I would be delighted to come. I see you have me down for two presentations and you know that I always have a great time at the summer schools and meetings. The Retreat last year kept the tradition of great meetings with unbelievable and fantastic interactions. What can be better. I look forward to the details for travel, etc. My wife asked me how I would be able to turn down your invitation; no way. - Charles L Hoppel
Preliminary programme MiPschool
- The MiPschool will focus on basic concepts on mitochondrial respiratory states and applications of substrate-uncoupler-inhibitor titration (SUIT) protocols. - Last update: 2017-05-31
- Mitochondrial respiratory control: MITOEAGLE recommendations 1
- 2017-07-27
- Arrival MiPschool
- ##:## Joint dinner
- ##:## Welcome by the organizers Verena Laner - General Secretary MiPsociety and Erich Gnaiger - Chair COST ACTION MitoEAGLE
- 2017-07-24
- Session A (morning) Coupling and pathway control in oxidative phosphorylation
- 08:30-09:10
- Elemental steps towards understanding mitochondrial core energy metabolism: coupling control (Erich Gnaiger, Medical University of Innsbruck, AT).
- 09:10-09:40
- Biochemical coupling efficiency and ATP/O2 ratios (Charles L Hoppel, Case Western Reserve University School of Medicine, Ohio, US).
- 09:40-09:50 Selected abstract (A.1) Oral presentation
- 09:50-10:00 Selected abstract (A.2) Oral presentation
- 10:00-10:30 Coffee/tea break
- 10:30-11:10
- The electron transfer system β Q redox regulation and mitochondrial pathways to oxygen (Anthony L Moore, University of Sussex, UK).
- 11:10-11:40
- Respiratory pathway control in mitochondrial preparations (Gnaiger Erich, Medical University of Innsbruck, AT).
- 11:40-11:50 Selected abstract (A.3) Oral presentation
- 11:50-12:00 Selected abstract (A.4) Oral presentation
- 13:00-15:00 Walk & Talks, Run & Fun, Person-to-person poster talks or MIGHT!TM game time
- Session B (afternoon) Selected abstracts/Posters
- B1: ROS signaling, oxidative stress, cancer
- Session B (afternoon) Selected abstracts/Posters
- 15:00-15:10 Abstract (B1.1) Oral presentation
- 15:10-15:20 Abstract (B1.2) Oral presentation
- 15:20-16:00 Poster session and general discussion
- 16:00-16:30 Coffee/tea
- B2: Life style, degenerative diseases
- 16:30-16:40 Abstract (B2.1) Oral presentation
- 16:40-16:50 Abstract (B2.2) Oral presentation
- 16:50-17:00 Abstract (B2.3) Oral presentation
- 17:00-17:10 Abstract (B2.4) Oral presentation
- 17:10-17:20 Abstract (B2.5) Oral presentation
- 17:20-17:40 Poster session and general discussion
- 17:50-18:30
- B3. From Einstein's diffusion equation to Mitchellβs chemiosmotic equation: rates and states in the bioenergetics of oxidative phosphorylation (Erich Gnaiger, Medical University of Innsbruck, AT).
- 17:50-18:30
- 2017-07-25
- Session C (morning) OXPHOS protocols and data reporting
- 08:30-09:10
- Apparent Complex IV excess capacity and biochemical thresholds (Gnaiger Erich, Medical University of Innsbruck, AT).
- 09:10-09:40
- Substrate-uncoupler-inhibitor titration (SUIT) protocols β fundamental principles (Carolina Doerrier, OROBOROS INSTRUMENTS, AT).
- 09:40-09:50 Selected abstract (C.1) Oral presentation
- 09:50-10:00 Selected abstract (C.2) Oral presentation
- 10:00-10:30 Coffee/tea break
- 10:30-11:10
- Normalization of respiratory flux and flow.
- 11:10-11:40
- Respiratory control ratios and control factors (Gnaiger Erich, Medical University of Innsbruck, AT).
- 11:40-11:50 Selected abstract (C.3) Oral presentation
- 11:50-12:00 Selected abstract (C.4) Oral presentation
- 13:00-15:00 Walk & Talks, Run & Fun, Person-to-person poster talks or MIGHT!TM game time
- Session D (afternoon) Posters and selected abstracts
- D1. Models and mt-preparations in mitochondrial physiology
- Session D (afternoon) Posters and selected abstracts
- 15:00-15:10 Abstract (D1.1) Oral presentation
- 15:10-15:20 Abstract (D1.2) Oral presentation
- 15:20-15:30 Abstract (D1.3) Oral presentation
- 15:30-15:40 Abstract (D1.4) Oral presentation
- 15:40-15:50 Abstract (D1.5) Oral presentation
- 15:50-16:00 Abstract (D1.6) Oral presentation
- 16:00-16:30 Coffee/tea
- D2. Pharmacological intervention, toxicology, and regulation
- 16:30-16:40 Abstract (36) Oral presentation
- 16:40-16:50 Abstract (37) Oral presentation
- 16:50-17:00 Abstract (38) Oral presentation
- 17:00-17:10 Abstract (39) Oral presentation
- 17:10-17:20 Abstract (40) Oral presentation
- 17:20-17:30 Abstract (41) Oral presentation
- 17:30-17:40 Abstract (42) Oral presentation
- 20:00-21:30
- Session D3 (evening) MITOEAGLE Early Career Investigators forum
- 20:00-21:30
- 2017-07-26
- Session E1 (morning) Clinical mitochondrial physiology
- 08:30-09:00
- The challenges of functional mitochondrial diagnosis (Charles L Hoppel, Case Western Reserve University School of Medicine, Ohio, US).
- 09:00-09:30
- Mitochondrial fitness in skeletal muscle (Pablo Garcia-Roves, University of Barcelona, ES).
- 09:30-10:00
- Scope and limitations of functional mitochondrial diagnosis in blood cells. (Anthony Molina,Department of Internal Medicine, US).
- 10:00-10:30 Coffee/tea break
- 10:30-11:00
- The scope of cryopreservation in blood cells for functional mitochondrial diagnosis. (Beata Velika, Pavol Jozef Ε afΓ‘rik University in Kosice, SK)
- 11:00-11:30
- Mitochondrial physiology in plants, alternative oxidases, and clinical perspectives (Anthony L Moore, University of Sussex, UK).
- 11:30-12:00
- Pyruvate therapy for mitochondrial diseases (Masashi Tanaka, Tokyo Metropolitan Institute of Gerontology, JP).
- 13:00-15:00 Walk & Talks, Run & Fun, Person-to-person poster talks or MIGHT!TM game time
- Session E2 (afternoon) Mitochondrial physiology: biomedical applications
- 15:00-15:30
- Mitochondrial function and dysfunction: ROS and Ca2+. (Werner Koopman, Radboud University Nijmegen Medical Centre, NL)
- 15:30-16:00
- Mitochondrial function and dysfunction in cancer (Richard K Porter, Trinity College Dublin, IE).
- 16:00-16:30 Coffee/tea
- 16:30-17:00
- The metabolic syndrome - dysmitochondrial syndrome and mitochondrial disruptors (Hong Kyu Lee, Eulji University College of Medicine, Seoul, KR).
- 17:00-17:30
- Mitochondrial function in aging and regeneration (Pidder Jansen-Duerr, University of Innsbruck, AT).
- 20:00 Conclusion and social programme with Raphael
- 2017-07-27
- Departure MiPschool
- Relaxing day for overall-participants
Preliminary programme MITOEAGLE Workshop WG1-4
- 2017-07-27
- Arrival MITOEAGLE workshop
- 20:00 Joint dinner
- 2017-07-28 to 29
- MITOEAGLE Workshop: WG1-4
- WG1: Harmonization of nomenclature on mitochondrial respiratory states and control parameters: Status of the consensus paper on a consistent terminology on mitochondrial physiology and bioenergetics; recommendations for the use of a common terminology in mitochondrial physiological research as a milestone towards unification of concepts and nomenclature.
- Β» Mitochondrial respiratory control: MITOEAGLE recommendations 1 - Manuscript in preparation by the MITOEAGLE Terminology Committee.
- Β» Add critical discussion on 'ATP production' (not to be confused with a difference of respiratory fluxes), 'glycolytic flux' (not to be confused with extracellular proton flux), 'reserve capacity' (is the difference of ETS capacity and ROUTINE respiratory activity a 'reserve'?), confusion of ETS capacity ('State 3u') and OXPHOS capacity, ..
- MITOEAGLE Workshop: WG1-4
- WG1: Respirometric reference protocols:
- Standard format for presenting substrate-uncoupler-inhibitor titration (SUIT) protocols for a βlibrary of protocolsβ applied in mitochondrial respiratory physiology.
- Criteria for selecting and recommending reference protocols.
- Documentation of the state-of-the-art standards in designing, conducting, reporting, interpreting, and validating SUIT protocols.
- Compare: Maelstrom Research program- data repository and harmonization.
- WG2-4: Data repositories
- 2017-07-30
- Departure MITOEAGLE
MiPschool 2017 Programme: Abstracts in sequential sessions
A: Coupling and pathway control in oxidative phosphorylation
- Monday, Jul 24, 08:30-12:00 Β»Help - Further information - Make full use of the MiPMap
Presentation | MiP areas | Mammals;models | Tissues;cells | Stress conditions | Pathological states | |
---|---|---|---|---|---|---|
Meszaros 2017 MiPschool Obergurgl | (Very) High-resolution respirometry β a deep dive into oxygen dependence of mitochondrial respiration. | Respiration Instruments;methods | Mouse | Liver Nervous system Kidney | ||
Hellgren 2017 MiPschool Obergurgl | Effect of prenatal hypoxia on adult mitochondrial respiration and ROS production. | Respiration | Mouse | Heart | Hypoxia | |
Sobotka 2017 MiPschool Obergurgl | Reference protocols for ROS production measurements. | Respiration | ||||
Komlodi 2017 MiPschool Obergurgl | Electron pressure exerted by convergent succinate- and glycerophosphate-pathways to the Q-junction regulate reversed electron transfer to Complex I and H2O2 production. | Respiration | Mouse | Nervous system | Oxidative stress;RONS | |
Gnaiger 2017 MiPschool A1 | Elemental steps towards understanding mitochondrial core energy metabolism: coupling control. | Respiration | ||||
Gnaiger 2017 MiPschool A4 | Respiratory pathway control in mitochondrial core energy metabolism: from bioenergetics to mitochondrial physiology. | Respiration | ||||
Moore 2017 MiPschool Obergurgl | The electron transfer-pathway β Q redox regulation and mitochondrial pathways to oxygen. | Respiration | ||||
Hoppel 2017 MiPschool Obergurgl A | Biochemical coupling efficiency and ATP/O2 ratios. |
B1: ROS signaling, oxidative stress, cancer - selected abstracts
- Monday, Jul 24, 14:30-16:00 Β»Help - Further information - Make full use of the MiPMap
Presentation | MiP areas | Mammals;models | Tissues;cells | Stress conditions | Pathological states | |
---|---|---|---|---|---|---|
Gainutdinov 2017 MiPschool Obergurgl | Different ways of reactive oxygen species (ROS) formation by brain mitochondria. | |||||
Silkuniene 2017 MiPschool Obergurgl | Mitochondrial glutamate dehydrogenase activity changes in response to hyperthermic treatment. | Human Other mammals Rat | Nervous system Liver Kidney Islet cell;pancreas;thymus Genital Fibroblast | Temperature | Cancer | |
Gasparrini 2017 MiPschool Obergurgl | Anti-inflammatory effects of strawberry and honey extracts in RAW 264.7 macrophages stressed with LPS. | Respiration Comparative MiP;environmental MiP Pharmacology;toxicology | Mouse | Macrophage-derived | Oxidative stress;RONS | |
Giampieri 2017 MiPschool Obergurgl | Strawberry extract protects human dermal fibroblasts against oxidative stress and improves mitochondrial functionality. | Respiration Exercise physiology;nutrition;life style Pharmacology;toxicology | Fibroblast | Oxidative stress;RONS | ||
Afrin 2017 MiPschool Obergurgl | Induction of mitochondrial dysfunction by Manuka honey as a strategy for prevention of colon cancer in vitro model: a rising role on reactive oxygen species, apoptosis, and cell metabolism. | Respiration | Cancer | |||
Brown 2017 MiPschool Obergurgl | Peroxisomes; underappreciated sources, including post glucose depletion but prior to ketosis, of mitochondrial energy substrates; medium fats and ACoA? Polyunsaturated fats being preferred peroxisomal substrates; energetic implications of Omega 3:6 imbalances, including for the brain. | Exercise physiology;nutrition;life style | Human | Oxidative stress;RONS | ||
Iglesias-Gonzalez 2017 MiPschool Obergurgl | Oscillations in mitochondrial ROS production as a new mechanism for cell cycle control. | |||||
Karavyraki 2017 MiPschool Obergurgl | Mitochondrial function and morphology linked to metabolic differences in normal, dysplastic and cancerous oral cells. | Respiration | Human | Cancer | ||
Hoel 2017 MiPschool Obergurgl | A study on mitochondrial stress responses due to OXPHOS inhibition. | Respiration mtDNA;mt-genetics | Human | Nervous system |
B2: Life style, degenerative diseases
- Monday, Jul 24, 16:30-18:00 Β»Help - Further information - Make full use of the MiPMap
Presentation | MiP areas | Mammals;models | Tissues;cells | Stress conditions | Pathological states | |
---|---|---|---|---|---|---|
Amick 2017 MiPschool Obergurgl | Bioenergetic profiling of mitochondria isolated from three distinct brain regions relevant to AD pathology in non-human primates. | Respiration | Other mammals | Nervous system | Alzheimer's | |
Collins 2017 MiPschool Obergurgl | The effects of a Mediterranean versus Western diet on nonhuman primate skeletal muscle bioenergetics. | Respiration Exercise physiology;nutrition;life style | ||||
Ene 2017 MiPschool Obergurgl | Isolated mitochondria transfer restores schizophrenia related deficits in-vitro and in-vivo. | Rat | Nervous system | |||
Isola 2017 MiPschool Obergurgl | Do mitochondria counteract diabetes impairment by means of morphological and physiological strategies? | Rat | Diabetes | |||
Sharma 2017 MiPschool Obergurgl | Role of ATP-sensitive potassium (KATP) and maxi potassium (BKCa) channels in beta3-adrenoceptors mediated tocolytic effect and involvement of associated mitochondrial calcium dynamics pathways in buffaloes (Bubalus bubalis). | Bovines | Genital | |||
Soares 2017 MiPschool Obergurgl | Oxidative metabolism during hyperglycemia in individuals with obesity assessed by near infrared spectroscopy. | Human | Obesity | |||
Distefano 2017 MiPschool Obergurgl | Effects of calorie restriction-induced weight loss and exercise on skeletal muscle mitochondrial energetics of older obese subjects. | Respiration Exercise physiology;nutrition;life style | Human | Skeletal muscle | Obesity | |
Krylova 2017 MiPschool Obergurgl | High-resolution respirometry in diagnostic of mitochondrial complex I deficiency. | Respiration mtDNA;mt-genetics mt-Medicine | Endothelial;epithelial;mesothelial cell Fibroblast | |||
Crisostomo 2017 MiPschool Obergurgl | Glycerol metabolism in testicular cells β a mitochondrial tale that may control male reproductive potential. | |||||
Pavlovic 2017 MiPschool Obergurgl | Establishing cellular model for studying mechanisms of muscle insulin resistance: towards understanding the role of mitochondria. |
C: OXPHOS protocols and data reporting
- Tuesday, Jul 25, 08:30-12:00 Β»Help - Further information - Make full use of the MiPMap
Presentation | MiP areas | Mammals;models | Tissues;cells | Stress conditions | Pathological states | |
---|---|---|---|---|---|---|
Nogueras 2017 MiPschool Obergurgl | Mitochondrial dysfunction in peripheral blood mononuclear cells from multiple sclerosis patients. | Respiration Patients | Blood cells | Neurodegenerative | ||
Siewiera 2017 MiPschool Obergurgl | Blood platelets as bioenergetic markers of brain damage in STZ-diabetes. | Respiration | Rat | Blood cells Platelet | Diabetes | |
Garcia-Souza 2017 MiPschool Obergurgl | Assessment of mitochondrial respiratory function in cryopreserved platelets. | Respiration | Human | Blood cells Platelet | Cryopreservation | |
Keppner 2017 MiPschool Obergurgl | Different respiratory states to determine LEAK and uncoupled respiration in the SUIT protocol: effect and consequences. | Respiration | Blood cells | |||
Gnaiger 2017 MiPschool C1 | Apparent Complex IV excess capacity and biochemical thresholds. | Respiration | ||||
Doerrier 2017 MiPschool C2 | Substrate-uncoupler-inhibitor titration (SUIT) protocols β fundamental principles. | Respiration Comparative MiP;environmental MiP | Human Mouse | Heart Nervous system HEK | Cryopreservation | |
Gnaiger 2017 MiPschool C4 | Respiratory control ratios and control factors |
D1: Models and mt-preparations in mitochondrial physiology - selected abstracts
- Tuesday, Jul 25, 14:30-16:00 Β»Help - Further information - Make full use of the MiPMap
Presentation | MiP areas | Mammals;models | Tissues;cells | Stress conditions | Pathological states | |
---|---|---|---|---|---|---|
Iyer 2017b MiPschool Obergurgl | Patient-specific stem cell models for mitochondrial diseases. | mtDNA;mt-genetics | Fibroblast Stem cells | Other | ||
Juhasz 2017 MiPschool Obergurgl | Blockade of N-methyl-D-aspartate receptors improves polymicrobial sepsis-evoked mitochondrial dysfunction in rats. | Respiration | Rat | Liver | Other | |
McKenna 2017 MiPschool Obergurgl | A systematic review of the use of respirometry in critically ill patients. | Respiration mt-Medicine Patients | ||||
Markova 2017 MiPschool Obergurgl | Mitochondrial respiration in the rat left heart ventricle after inhibition of pyruvate dehydrogenase kinase. | Respiration | Rat | Heart | Oxidative stress;RONS | |
Bento 2017 MiPschool Obergurgl | Isolation of human urine-derived stem cells for mitochondrial function profile assessment. | |||||
Krajcova 2017 MiPschool Obergurgl | Developing a method of assessing mitochondrial functions in homogenates of human heart muscle. | |||||
Rao 2017 MiPSchool Obergurgl | Coauthor of Iyer 2017b MiPschool Obergurgl and Iyer 2017a MiPschool Obergurgl | |||||
Petit 2017 MiPschool Obergurgl | Role of oxaloacetate decarboxylase FAHD1 in regulation of cell proliferation and cellular senescence. | Respiration | Human | Endothelial;epithelial;mesothelial cell | Aging;senescence Cancer | |
Holzknecht 2017 MiPschool Obergurgl | Metabolic characterization of Fahd1 knock-out cardiomyocytes in a mammalian model organism - an outlook. | Respiration Genetic knockout;overexpression | Mouse | Heart |
D2: Pharmacological intervention, toxicology, and regulation - selected abstracts
- Tuesday, Jul 25, 16:30-18:00 Β»Help - Further information - Make full use of the MiPMap
Presentation | MiP areas | Mammals;models | Tissues;cells | Stress conditions | Pathological states | |
---|---|---|---|---|---|---|
Dias 2017 MiPschool Obergurgl | Differential effects of epigallocatechin-3-gallate and L-theanine on the proliferation and mitochondrial functionality of human Sertoli cells. | Exercise physiology;nutrition;life style Pharmacology;toxicology | Human | Genital | ||
Bernardino 2017 MiPschool Obergurgl | Mitochondrial biogenesis and morphological alterations in human Sertoli cells after carbonic anydrase inhibition. | mt-Biogenesis;mt-density mtDNA;mt-genetics | Human | Genital | ||
Varela-Lopez 2017 MiPschool Obergurgl | Mitochondrial function impairment after Duxorubicin treatment is attenuated by strawberry intake in old and young rats. | Respiration Exercise physiology;nutrition;life style Pharmacology;toxicology | Rat | Liver | Aging;senescence | |
Forbes-Hernandez 2017 MiPschool Obergurgl | The reduction of mitochondrial functionality by a strawberry extract: a mechanism that contributes to its lipid-lowering effect? | Respiration mt-Biogenesis;mt-density Pharmacology;toxicology | Human | Liver | ||
Baraldo 2017 MiPschool Obergurgl | Fahd-1 links metabolism and neuronal activity in C. elegans. | Caenorhabditis elegans | Aging;senescence Neurodegenerative | |||
Reboredo-Rodriguez 2017 MiPschool Obergurgl | Protective effect of a polyphenol-rich strawberry extract on oxidative and endoplasmic reticulum stresses in HepG2 cell line. | Respiration Pharmacology;toxicology | Human | Liver | ||
Liebscher 2017 MiPschool Obergurgl | The LAMTOR complex in regulation of fat metabolism. | Respiration mtDNA;mt-genetics Genetic knockout;overexpression | Mouse | Fat | ||
Ferreira 2017 MiPschool Obergurgl | Doxorubicin toxicity and mitochondrial dysfunction in mouse induced pluripotent stem cells-derived cardiomyocytes. |
E1: Clinical mitochondrial physiology
- Wednesday, Jul 26, 08:30-10:00 Β»Help - Further information - Make full use of the MiPMap
Presentation | MiP areas | Mammals;models | Tissues;cells | Stress conditions | Pathological states | |
---|---|---|---|---|---|---|
Tanaka 2017 MiPschool Obergurgl | Metabolomic analysis of the effect of heavy water on mitochondrial oxidative phosphorylation. | Pharmacology;toxicology | Mouse | Nervous system | ||
Garcia-Roves 2017 MiPschool Obergurgl | Mitochondrial fitness in skeletal muscle. | Respiration Comparative MiP;environmental MiP Exercise physiology;nutrition;life style mt-Medicine | Skeletal muscle | |||
Hoppel 2017 MiPschool Obergurgl E1 | The challenges of functional mitochondrial diagnosis. | nDNA;cell genetics mt-Medicine | Skeletal muscle | |||
Cizmarova 2017 MiPschool Obergurgl | The scope of cryopreservation in blood cells for functional mitochondrial diagnosis. | Respiration mt-Medicine | Blood cells | Cryopreservation | ||
Molina 2017 MiPschool Obergurgl | Scope and limitations of functional mitochondrial diagnosis in blood cells. | mt-Medicine | Blood cells | |||
Moore 2017 MiPschool Obergurgl E1 | Mitochondrial physiology in plants, alternative oxidases, and clinical perspectives. |
E2: Mitochondrial physiology: biomedical applications
- Wednesday, Jul 26, 10:30-12:00 Β»Help - Further information - Make full use of the MiPMap
Presentation | MiP areas | Mammals;models | Tissues;cells | Stress conditions | Pathological states | |
---|---|---|---|---|---|---|
Jansen-Duerr 2017 MiPschool Obergurgl | Role of mitochondria in ageing and regeneration. | mt-Medicine | ||||
Koopman 2017 MiPschool Obergurgl | Mitochondrial function and dysfunction: ROS detection and redox analysis. Koopman_Presenation | Instruments;methods | Oxidative stress;RONS | |||
Lee 2017 MiPschool Obergurgl | The metabolic syndrome (MetS) - dysmitochondrial syndrome and mitochondrial disruptors. Lee_Presentation | Comparative MiP;environmental MiP mt-Medicine mt-Awareness | Human | Diabetes Obesity | ||
Porter 2017 MiPschool Obergurgl | Mitochondrial function and dysfunction in cancer. | Cancer |
MITOEAGLE Working Groups Workshop 2017 Programme: Abstracts in sequential sessions
- Friday and Saturday, Jul 28 and 29, 09:00-12:00 16:00-19:00 Β»Help - Further information - Make full use of the MiPMap
Presentation | MiP areas | Mammals;models | Tissues;cells | Stress conditions | Pathological states | |
---|---|---|---|---|---|---|
Krajcova 2017 MITOEAGLE Obergurgl | Developing a method of assessing mitochondrial functions in homogenates of human heart muscle. | Respiration Pharmacology;toxicology | Human | Cardiovascular | ||
Chabi 2017 MITOEAGLE Obergurgl | Optimization of permeabilized fibers preparation for mitochondrial respiration measurements using Design of Experiments methodology. | Respiration | Mouse | Skeletal muscle | ||
Pavlovic 2017 MITOEAGLE Obergurgl | Establishing cellular model for studying mechanisms of muscle insulin resistance: towards understanding the role of mitochondria. | Respiration mt-Medicine mt-Awareness | Mouse | Skeletal muscle | Diabetes | |
Gainutdinov 2017 MITOEAGLE Obergurgl | Different ways of reactive oxygen species (ROS) formation by brain mitochondria. | Respiration | Mouse Rat | Nervous system | Oxidative stress;RONS | |
Ukropec 2017 MITOEAGLE Obergurgl | Could functional state of muscle mitochondria reflect exercise-induced changes in insulin sensitivity, glucose tolerance and cognitive performance in individuals with mild cognitive impairment? | Respiration Exercise physiology;nutrition;life style | Skeletal muscle | Aging;senescence Diabetes Neurodegenerative | ||
Bento 2017 MITOEAGLE Obergurgl | Isolation of human urine-derived stem cells for mitochondrial function profile assessment. | Respiration | Human | Stem cells | ||
Ferreira 2017 MITOEAGLE Obergurgl | Doxorubicin toxicity and mitochondrial dysfunction in mouse induced pluripotent stem cells-derived cardiomyocytes. | Pharmacology;toxicology Respiration | Mouse | Heart Stem cells | ||
Waldauf 2017 MITOEAGLE Obergurgl | Effect of propofol on energy metabolism in an in vitro model of human skeletal muscle homogenates. | Respiration Pharmacology;toxicology | Human | Skeletal muscle | ||
Garcia-Roves 2017 MITOEAGLE Obergurgl | MitoEAGLE data repository on muscle tissues - current status. | |||||
Muntane 2017 MITOEAGLE Obergurgl | Integration of oxidative and nitrosative stress in the overall cell death signaling induced by Sorafenib in hepatoma cells. | Pharmacology;toxicology | Human | Liver | Cell death Oxidative stress;RONS | Cancer |
Dubouchaud 2017 MITOEAGLE Obergurgl | Effects of a single bout of exercise on the production of reactive oxygen species in muscle and liver isolated mitochondria. | Exercise physiology;nutrition;life style Respiration | Rat | Skeletal muscle Liver | Oxidative stress;RONS | |
Crisostomo 2017 MITOEAGLE Obergurgl | Glycerol metabolism in testicular cells β a mitochondrial tale that may control male reproductive potential. | Human | Genital | |||
Iglesias-Gonzalez 2017 MITOEAGLE Obergurgl | Oscillations in mitochondrial ROS production as a new mechanism for cell cycle control. | Respiration mt-Medicine | Oxidative stress;RONS | |||
Scatena 2017 MITOEAGLE Obergurgl | Cancer stem cell differentiation induced by PPAR ligands. Which role for an inhibition of mitochondrial respiratory chain? | Pharmacology;toxicology | Human | Liver | Cancer |
Abstracts
- Abstract submission extended: until 2017 July 12
- The abstract title has to be included on the registration form.
- Categories: Early career investigators (ECI) and students are invited to submit abstracts until June 15 in five alternative categories and apply with their submission for a MITOEAGLE Scholarship:
- Your own project in the context of mitochondrial physiology.
- SUIT protocols: basic concepts. - Β» MitoPedia: SUIT
- SUIT protocols: various applications with intact cells and mt-preparations.
- Definitions and controversies for a selected term on respiratory states and respiratory control ratios. - Β» MitoPedia: Respiratory states, MitoPedia: Respiratory control ratios
- Definition of a term in the context of mitochondrial physiology that is missing in MitoPedia. - Β» MitoPedia
- NOTE: If you have an idea or abstract in the context of mitochondrial research, that appears to not fit into one of the categories stated above, don't hesitate to contact us. We are open to new ideas!
- Format
- Abstract submission and review for MITOEAGLE Scholarships
- 1. Eligibility: Early career investigators and students from all COST countries and International Partner Countries can apply - MITOEAGLE network.
- 2. Submit your abstract in the format given above: [email protected]
- 3. Optionally, select a 'MITOEAGLE mentor' who will act as the contact to review your abstract and recommend you as a recipient of the MITOEAGLE scholarship. Add the name of your selected mentor as a final section of your abstract. Click on the highlighted name of the MITOEAGLE mentor for contact details, and send your abstract in Cc to your mentor.
- 4. Experimental abstracts will be reviewed and accepted entirely independent of the experimental platform used in the study, and a wide variety of experimental approaches is highly welcome.
Abstracts/Participants - alphabetical order
Presentation | Session | |
---|---|---|
Afrin 2017 MiPschool Obergurgl | Induction of mitochondrial dysfunction by Manuka honey as a strategy for prevention of colon cancer in vitro model: a rising role on reactive oxygen species, apoptosis, and cell metabolism. | B1 Poster |
Amick 2017 MiPschool Obergurgl | Bioenergetic profiling of mitochondria isolated from three distinct brain regions relevant to AD pathology in non-human primates. | Oral B2 |
Ashcroft 2017 MiPschool Obergurgl | No abstract. | |
Baraldo 2017 MiPschool Obergurgl | Fahd-1 links metabolism and neuronal activity in C. elegans. | D2 Oral |
Bekebrede 2017 MiPschool Obergurgl | No abstract. | |
Bento 2017 MiPschool Obergurgl | Isolation of human urine-derived stem cells for mitochondrial function profile assessment. | D1 |
Bernardino 2017 MiPschool Obergurgl | Mitochondrial biogenesis and morphological alterations in human Sertoli cells after carbonic anydrase inhibition. | D2 Oral |
Bezuidenhout 2017 MiPschool Obergurgl | No abstract. | |
Brown 2017 MiPschool Obergurgl | Peroxisomes; underappreciated sources, including post glucose depletion but prior to ketosis, of mitochondrial energy substrates; medium fats and ACoA? Polyunsaturated fats being preferred peroxisomal substrates; energetic implications of Omega 3:6 imbalances, including for the brain. | B1 Oral |
Cizmarova 2017 MiPschool Obergurgl | The scope of cryopreservation in blood cells for functional mitochondrial diagnosis. | E1 Review |
Collins 2017 MiPschool Obergurgl | The effects of a Mediterranean versus Western diet on nonhuman primate skeletal muscle bioenergetics. | B2 Oral |
Crisostomo 2017 MiPschool Obergurgl | Glycerol metabolism in testicular cells β a mitochondrial tale that may control male reproductive potential. | B2 Poster |
Di Nolfo 2017 MiPschool Obergurgl | Middle cerebral artery modification in mouse model of Marfan Syndrom and potential role of Nox4. | |
Dias 2017 MiPschool Obergurgl | Differential effects of epigallocatechin-3-gallate and L-theanine on the proliferation and mitochondrial functionality of human Sertoli cells. | D2 Oral |
Distefano 2017 MiPschool Obergurgl | Effects of calorie restriction-induced weight loss and exercise on skeletal muscle mitochondrial energetics of older obese subjects. | B2 Oral |
Doerrier 2017 MiPschool C2 | Substrate-uncoupler-inhibitor titration (SUIT) protocols β fundamental principles. | C1 Review |
Ene 2017 MiPschool Obergurgl | Isolated mitochondria transfer restores schizophrenia related deficits in-vitro and in-vivo. | B2 Oral |
Ferreira 2017 MiPschool Obergurgl | Doxorubicin toxicity and mitochondrial dysfunction in mouse induced pluripotent stem cells-derived cardiomyocytes. | D2 |
Forbes-Hernandez 2017 MiPschool Obergurgl | The reduction of mitochondrial functionality by a strawberry extract: a mechanism that contributes to its lipid-lowering effect? | D2 Poster |
Gainutdinov 2017 MiPschool Obergurgl | Different ways of reactive oxygen species (ROS) formation by brain mitochondria. | B1 Poster |
Garcia-Roves 2017 MiPschool Obergurgl | Mitochondrial fitness in skeletal muscle. | E1 Review |
Garcia-Souza 2017 MiPschool Obergurgl | Assessment of mitochondrial respiratory function in cryopreserved platelets. | C1 Oral |
Gasparrini 2017 MiPschool Obergurgl | Anti-inflammatory effects of strawberry and honey extracts in RAW 264.7 macrophages stressed with LPS. | B1 Poster |
Gerna 2017 MiPschool Obergurgl | No abstract. | |
Ghanim 2017 MiPschool Obergurgl | HAMLET derivatives as a pre-operative therapy in oesophageal cancer. | |
Giampieri 2017 MiPschool Obergurgl | Strawberry extract protects human dermal fibroblasts against oxidative stress and improves mitochondrial functionality. | B1 Poster |
Gnaiger 2017 MiPschool A1 | Elemental steps towards understanding mitochondrial core energy metabolism: coupling control. | A1 Review |
Gnaiger 2017 MiPschool A4 | Respiratory pathway control in mitochondrial core energy metabolism: from bioenergetics to mitochondrial physiology. | A1 Review |
Gnaiger 2017 MiPschool C1 | Apparent Complex IV excess capacity and biochemical thresholds. | Review C1 |
Gnaiger 2017 MiPschool C4 | Respiratory control ratios and control factors | Review C1 |
Hellgren 2017 MiPschool Obergurgl | Effect of prenatal hypoxia on adult mitochondrial respiration and ROS production. | A1 Oral |
Hoel 2017 MiPschool Obergurgl | A study on mitochondrial stress responses due to OXPHOS inhibition. | B1 |
Holzknecht 2017 MiPschool Obergurgl | Metabolic characterization of Fahd1 knock-out cardiomyocytes in a mammalian model organism - an outlook. | Oral D1 |
Hoppel 2017 MiPschool Obergurgl A | Biochemical coupling efficiency and ATP/O2 ratios. | A1 Review |
Hoppel 2017 MiPschool Obergurgl E1 | The challenges of functional mitochondrial diagnosis. | E1 Review |
Iglesias-Gonzalez 2017 MiPschool Obergurgl | Oscillations in mitochondrial ROS production as a new mechanism for cell cycle control. | B1 |
Irving 2017 MiPSchool Obergurgl | No abstract. | |
Isola 2017 MiPschool Obergurgl | Do mitochondria counteract diabetes impairment by means of morphological and physiological strategies? | B2 Oral |
Iyer 2017a MiPschool Obergurgl | A science-based strategy game for understanding mitochondrial bioenergetics. | |
Iyer 2017b MiPschool Obergurgl | Patient-specific stem cell models for mitochondrial diseases. | D1 Oral |
Jansen-Duerr 2017 MiPschool Obergurgl | Role of mitochondria in ageing and regeneration. | E2 Review |
Juhasz 2017 MiPschool Obergurgl | Blockade of N-methyl-D-aspartate receptors improves polymicrobial sepsis-evoked mitochondrial dysfunction in rats. | D1 Oral |
Kamel 2017 MiPschool Obergurgl | No abstract. | |
Karavyraki 2017 MiPschool Obergurgl | Mitochondrial function and morphology linked to metabolic differences in normal, dysplastic and cancerous oral cells. | B1 |
Keppner 2017 MiPschool Obergurgl | Different respiratory states to determine LEAK and uncoupled respiration in the SUIT protocol: effect and consequences. | C1 Oral |
Komlodi 2017 MiPschool Obergurgl | Electron pressure exerted by convergent succinate- and glycerophosphate-pathways to the Q-junction regulate reversed electron transfer to Complex I and H2O2 production. | A1 Oral |
Koopman 2017 MiPschool Obergurgl | Mitochondrial function and dysfunction: ROS detection and redox analysis. Koopman_Presenation | E2 Review |
Krajcova 2017 MiPschool Obergurgl | Developing a method of assessing mitochondrial functions in homogenates of human heart muscle. | D1 |
Krylova 2017 MiPschool Obergurgl | High-resolution respirometry in diagnostic of mitochondrial complex I deficiency. | B2 Poster |
Lee 2017 MiPschool Obergurgl | The metabolic syndrome (MetS) - dysmitochondrial syndrome and mitochondrial disruptors. Lee_Presentation | E2 Review |
Liebscher 2017 MiPschool Obergurgl | The LAMTOR complex in regulation of fat metabolism. | D2 Oral |
Markova 2017 MiPschool Obergurgl | Mitochondrial respiration in the rat left heart ventricle after inhibition of pyruvate dehydrogenase kinase. | D1 Oral |
McKenna 2017 MiPschool Obergurgl | A systematic review of the use of respirometry in critically ill patients. | D1 Oral |
Meszaros 2017 MiPschool Obergurgl | (Very) High-resolution respirometry β a deep dive into oxygen dependence of mitochondrial respiration. | A1 Oral |
Molina 2017 MiPschool Obergurgl | Scope and limitations of functional mitochondrial diagnosis in blood cells. | E1 |
Moore 2017 MiPschool Obergurgl | The electron transfer-pathway β Q redox regulation and mitochondrial pathways to oxygen. | A1 Review |
Moore 2017 MiPschool Obergurgl E1 | Mitochondrial physiology in plants, alternative oxidases, and clinical perspectives. | E1 Review |
Nogueras 2017 MiPschool Obergurgl | Mitochondrial dysfunction in peripheral blood mononuclear cells from multiple sclerosis patients. | C1 Oral |
Nozickova 2017 MiPschool Obergurgl | Sulfite oxidase. | |
Pavlovic 2017 MiPschool Obergurgl | Establishing cellular model for studying mechanisms of muscle insulin resistance: towards understanding the role of mitochondria. | B2 |
Petit 2017 MiPschool Obergurgl | Role of oxaloacetate decarboxylase FAHD1 in regulation of cell proliferation and cellular senescence. | Oral D1 |
Porter 2017 MiPschool Obergurgl | Mitochondrial function and dysfunction in cancer. | E2 |
Pranger 2017 MiPschool Obergurgl | No abstract. | |
Rao 2017 MiPSchool Obergurgl | Coauthor of Iyer 2017b MiPschool Obergurgl and Iyer 2017a MiPschool Obergurgl | D1 |
Reboredo-Rodriguez 2017 MiPschool Obergurgl | Protective effect of a polyphenol-rich strawberry extract on oxidative and endoplasmic reticulum stresses in HepG2 cell line. | D2 Poster |
Salti 2017 MiPschool Obergurgl | No abstract. | |
Schartner 2017 MiPschool Obergurgl | No abstract. | |
Schoepp 2017 MiPschool Obergurgl | Generation and characterization of human cardiomyocytes obtained from iPSCs derived from patients with Friedreichβs ataxia. | |
Sharma 2017 MiPschool Obergurgl | Role of ATP-sensitive potassium (KATP) and maxi potassium (BKCa) channels in beta3-adrenoceptors mediated tocolytic effect and involvement of associated mitochondrial calcium dynamics pathways in buffaloes (Bubalus bubalis). | B2 Poster |
Shi 2017 MiPschool Obergurgl | No abstract. | |
Siewiera 2017 MiPschool Obergurgl | Blood platelets as bioenergetic markers of brain damage in STZ-diabetes. | C1 Oral |
Silkuniene 2017 MiPschool Obergurgl | Mitochondrial glutamate dehydrogenase activity changes in response to hyperthermic treatment. | B1 Oral |
Soares 2017 MiPschool Obergurgl | Oxidative metabolism during hyperglycemia in individuals with obesity assessed by near infrared spectroscopy. | B2 Oral |
Sobotka 2017 MiPschool Obergurgl | Reference protocols for ROS production measurements. | A1 Oral |
Stevens 2017 MiPschool Obergurgl | No abstract. | |
Tanaka 2017 MiPschool Obergurgl | Metabolomic analysis of the effect of heavy water on mitochondrial oxidative phosphorylation. | E1 Review |
Varela-Lopez 2017 MiPschool Obergurgl | Mitochondrial function impairment after Duxorubicin treatment is attenuated by strawberry intake in old and young rats. | D2 Poster |
Venz 2017 MiPschool Obergurgl | No abstract. | |
Waldauf 2017 MiPschool Obergurgl | Effect of propofol on energy metabolism in an in vitro model of human skeletal muscle homogenates. | Oral |
Yuan 2017 MiPschool Obergurgl | Participant MiPschool Obergurgl 2017. |
Support
MITOEAGLE scholarships for Early Career Investigators and students
- Submitted abstracts provide the basis for allocation of MITOEAGLE scholarships.
- Proposed deadline: 2017-Jun-15.
- 42 basic scholarships will cover the local costs (accommodation, meals and registration).
- Students from Inclusiveness Target Countries are eligible for extended scholarships covering travel costs in addition to the basic scholarship.
- Abstracts submitted with data suitable for the data bases Working Groups 2, 3 and 4 or Working Group 1 are selected as a basis of additional support for joining the MITOEAGLE Workshop WG1-4 (Jul 27-30).
- MITOEAGLE Working Group participants are supported (as far as possible) to join the Training School to be better prepared for the collaboration in the WG meeting, particularly the group working on the terminology review on respiratory states.
- Β» Notification of MITOEAGLE scholarships will be given shortly.
MiPscholarships
- The Mitochondrial Physiology Society supports the participation at MiPschool with scholarships for students and early career investigators.
Scholarships by the Medical University of Innsbruck
- 10 students of the Medical University of Innsbruck will be supported by a scholarship. The scholarship will cover 80% of the registration/accommodation costs.
- Β» For further questions, please contact the MITOEAGLE representatives of the training schools:
- Β» Further details on mentorship: consult MITOEAGLE Early Career Investigators
- Β» List of MITOEAGLE mentors
ECTS for students of the Medical University of Innsbruck
- Β» For attending this conference, you will receive a credit of 1.5 ECTS.
Registration
MiPschool registration Early Career Investigators and students
MITOEAGLE Workshop WG1-4
- Β» Registration form
- Please send the completed form to [email protected]
Travel info
- When and how to travel? Further details Β» Travel info
Sponsors
Organizers
- Georg Kandolf - Abstracts
- Verena Laner MiPsociety General Secretary - General conference organization
- Marija Beno, MITOEAGLE Administrative Representative - General conference organization
- Erich Gnaiger, Chair COST Action MITOEAGLE and Chair MiPsociety - Main organizer
10 years ago
Listed under MitoGlobal Events.
Labels:
2017, ORO, MitoFit, MITOEAGLE, Next, MiP