Difference between revisions of "Template:SUIT-009"
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::: '''[[Categories of SUIT protocols |SUIT-category]]:''' NS(P) | ::: '''[[Categories of SUIT protocols |SUIT-category]]:''' NS(P) | ||
::: '''[[SUIT protocol pattern]]:''' diametral 1S;2D;3P;4Rot;5Ama | ::: '''[[SUIT protocol pattern]]:''' diametral 1S;2D;3P;4Rot;5Ama | ||
{| class="wikitable" border="1" | |||
{{Template:SUIT header}} | |||
|- | |||
| 1S | |||
| [[S]]<sub>''L''</sub> | |||
| [[S]] | |||
| CII | |||
| S<sub>''L''</sub> or S_L: Succinate, S-LEAK respiration, S<sub>''L''</sub> | |||
{{Template:SUIT S}} {{Template:SUIT L n}} | |||
|- | |||
| 2D | |||
| [[S]]<sub>''P''</sub> | |||
| [[S]] | |||
| CII | |||
| 1S;2D | |||
{{Template:SUIT S}} {{Template:SUIT OXPHOS}} | |||
|- | |||
| 3P | |||
| [[NS]]<sub>''P''</sub> | |||
| [[NS]] | |||
| CI&II | |||
| 1S;2D;3P | |||
{{Template:SUIT N}} & {{Template:SUIT S}} {{Template:SUIT NS}} {{Template:SUIT OXPHOS}} | |||
|- | |||
| 4Rot | |||
| [[S]]<sub>''P''</sub> | |||
| [[S]] | |||
| CII | |||
| 1S;2D;3P;4Rot | |||
{{Template:SUIT S}} {{Template:SUIT OXPHOS}} {{Template:SUIT Rot}} | |||
|- | |||
| 6Ama | |||
| [[ROX]] | |||
| | |||
| | |||
| {{Template:SUIT Ama}} | |||
|} | |||
{{Template:SUIT CIV}} | |||
{{Template:Keywords in SUIT protocols}} |
Revision as of 10:51, 21 January 2019
Description
Abbreviation: NS(P)
Reference: A »Versions
- SUIT-category: NS(P)
- SUIT protocol pattern: diametral 1S;2D;3P;4Rot;5Ama
Step | State | Pathway | Q-junction | Comment - Events (E) and Marks (M) |
---|---|---|---|---|
1S | SL | S | CII | SL or S_L: Succinate, S-LEAK respiration, SL
Succinate, S ( type S-pathway to Q). Template:SUIT L n |
2D | SP | S | CII | 1S;2D
Succinate, S ( type S-pathway to Q). OXPHOS capacity P (with saturating [ADP]), active OXPHOS state. |
3P | NSP | NS | CI&II | 1S;2D;3P
NADH-linked substrates (type N-pathway to Q). & Succinate, S ( type S-pathway to Q). Respiratory stimulation by simultaneous action of type N substrates & succinate, with convergent electron flow in the NS-pathway for reconstitution of TCA cycle function. OXPHOS capacity P (with saturating [ADP]), active OXPHOS state. |
4Rot | SP | S | CII | 1S;2D;3P;4Rot
Succinate, S ( type S-pathway to Q). OXPHOS capacity P (with saturating [ADP]), active OXPHOS state. Succinate pathway control state (S-pathway) after inhibiting CI with rotenone, which also inhibits the F-pathway.
|
6Ama | ROX | Rox is the residual oxygen consumption in the ROX state, due to oxidative side reactions, estimated after addition of antimycin A (inhibitor of CIII). Rox is subtracted from oxygen flux as a baseline for all respiratory states, to obtain mitochondrial respiration (mt). |
Step | Respiratory state | Pathway control | ET-Complex | Comment |
---|---|---|---|---|
## AsTm | AsTmE | CIV | CIV | |
## Azd | CHB |
- Bioblast links: SUIT protocols - >>>>>>> - Click on [Expand] or [Collapse] - >>>>>>>
- Coupling control
- Pathway control
- Main fuel substrates
- » Glutamate, G
- » Glycerophosphate, Gp
- » Malate, M
- » Octanoylcarnitine, Oct
- » Pyruvate, P
- » Succinate, S
- Main fuel substrates
- Glossary