Difference between revisions of "MitoEAGLE data: muscle"
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Revision as of 14:59, 27 April 2016
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News and Events |  |
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Working Groups | Short-Term Scientific Missions | Management Committee | Members |  |
COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping
MitoEAGLE data: muscle
WG2
- MITOEAGLE data repository in muscle and other tissues
WG2 Description
- During the past 10 years, a dramatically increasing number of studies report respirometric data on human muscle tissue (e.g. Christiansen 2015 Am J Physiol). Muscle mitochondrial function is particularly studied in genetically engineered mouse models of human diseases (e.g. Jelenik 2014 Diabetes). However, despite the many published data, lack of consistency often precludes quantitative comparison among data sets with permeabilized or homogenized muscle fibres or isolated mitochondria, normalized to either tissue wet weight, dry weight, protein content, citrate synthase activity or other mitochondrial markers. In the absence of validated conversion factors, these data remain largely unconnected and can only be qualitatively linked.
- The aim of WG2 will be to provide access to complete data sets for post-study statistical analysis and use harmonization tools (WG1) for standardized documentation, to initiate a data repository on muscle tissue from humans and model organisms in health and disease. Data sets shall be obtained from already published and new studies, prompting participating labs to report experimental details beyond those already published as far as possible (using tools such as PubMed Commons). As a result, specific protocols will be summarized for handling muscle tissue. Depending on specific interests, WG2 may decide to extend their focus to other tissue types.
WG2 Participants
| Country | City | Contact |
|---|---|---|
| Australia | Melbourne | Bishop David J |
| Austria | Innsbruck | Gnaiger Erich |
| Austria | Salzburg | Mayr JA |
| Austria | Innsbruck | Doerrier Carolina |
| Austria | Innsbruck | Laner Verena |
| Belgium | Leuven | Bird Matthew |
| Belgium | Liege | Votion Dominique-Marie |
| Brazil | Jaboticabal, SP | Garcia Geovana S |
| Brazil | São Paulo | Ferreira Julio Cesar B |
| Canada | Rimouski | Vandermeeren E |
| Canada | Vancouver | Boushel Robert C |
| Canada | Edmonton (Alberta) | Lemieux Helene |
| Canada | Antigonish | Kane Daniel A |
| Canada | Rimouski | Blier Pierre U |
| Croatia | Split | Mihanovic I |
| Croatia | Zagreb | Saric A |
| Czech Republic | Hradec Králové | Waldauf P |
| Czech Republic | Pilsen | Markova Michaela |
| Czech Republic | Prague 10 | Krajcova Adela |
| Czech Republic | Prague | Elkalaf Moustafa |
| Czech Republic | Pilsen | Kuncova J |
| Denmark | Hvidovre | Nehlin Jan O |
| Denmark | Copenhagen N | Mortensen OH |
| Denmark | Copenhagen | Dela Flemming |
| Denmark | Copenhagen | Larsen Steen |
| Denmark | Copenhagen | Gonzalez-Franquesa Alba |
| Denmark | Malov | Hey-Mogensen M |
| Estonia | Tartu | Paju Kalju |
| Estonia | Tallinn | Truu Laura |
| Estonia | Tallinn | Kaambre Tuuli |
| Estonia | Tallinn | Tepp Kersti |
| Estonia | Tallinn | Vendelin Marko |
| Estonia | Tallinn | Aid-Vanakova Jekaterina |
| Estonia | Tallinn | Karro N |
| Estonia | Tallinn | Puurand Marju |
| Finland | Jyvaeskylae | Lehti Maarit |
| Finland | Helsinki | Pirinen E |
| France | Montpellier | Cortade F |
| France | Bordeaux cedex | Mourier A |
| France | Grenoble Cedex 9 | Schlattner Uwe |
| France | Paris | Armand Anne-Sophie |
| France | Paris | Petit Patrice X |
| France | Montpellier Cedex 1 | Chabi Beatrice |
| France | Paris | Ventura-Clapier R |
| France | Grenoble cedex 9 | Dubouchaud Herve |
| Germany | Köln | Kimoloi Sammy |
| Germany | Leipzig | Ost Mario |
| Germany | Cologne | Pesta Dominik |
| Germany | Rostock | Haider F |
| Germany | Bremerhaven | Mark Felix Christopher |
| Germany | Nuthetal | Klaus S |
| Germany | Munich | Jastroch M |
| Germany | Bochum | Platen P |
| Germany | Düsseldorf | Granata Cesare |
| Germany | Duesseldorf | Roden Michael |
| Germany | Duesseldorf | Jelenik T |
| Greece | Heraklio | Sidiropoulou K |
| Greece | Athens | Trougakos Ioannis P |
| Greece | Heraklion | Tavernarakis Nektarios |
| India | Haryana | Sharma Vipin |
| Ireland | Dublin | O'Gorman Donal |
| Ireland | Dublin | Porter Richard K |
| Ireland | Sligo | Murphy J |
| Israel | Rishon Le Zion | Hachmo Yafit |
| Israel | Zrifin | Sova Marina |
| Israel | Jerusalem | Saada Reisch Ann |
| Italia | Udine | Salvadego Desy |
| Italy | Bologna | Genova Maria Luisa |
| Italy | Rome | Scatena Roberto |
| Italy | Pisa | Gastaldelli Amalia |
| Italy | Milan | De Palma Clara |
| Italy | Novara | Reano Simone |
| Italy | Milan | Giovarelli Matteo |
| Japan | Sapporo | Shirakawa R |
| Japan | Sapporo | Nambu H |
| Japan | Sapporo | Maekawa S |
| Latvia | Riga | Kuka Janis |
| Latvia | Riga | Zvejniece Liga |
| Latvia | Riga | Liepins Edgars |
| Latvia | Riga | Inashkina I |
| Luxembourg | Strassen | Devaux Yvan |
| Malta | Msida | Vella Joanna |
| Netherlands | Amsterdam | De Goede Paul |
| Netherlands | Maastricht | Hoeks Joris |
| Netherlands | Maastricht | Grevendonk L |
| Netherlands | Wageningen | Keijer Jaap |
| Netherlands | Maastricht | Van Polanen N |
| Netherlands | BT Amsterdam | Jaspers Richard T |
| Niederlande | ER Masstricht | De Theije C |
| Niederlande | ER Masstricht | De Wit-Verheggen V |
| Norway | Oslo | Nikolic N |
| Norway | Oslo | Lund Jenny |
| Norway | Oslo | Torp May-Kristin |
| Norway | Oslo | Rustan AC |
| Norway | Oslo | Eide L |
| Norway | Bergen | Tronstad Karl Johan |
| Norway | Tromsoe | Jansen Kirsten M |
| Norway | Tromsoe | Larsen Terje S |
| Norway | Tromsoe | Aasum E |
| Norway | Tromsoe | Schots Pauke C |
| Norway | Ullevål | Heiestad Christina |
| Poland | Lodz | Watala Cezary |
| Poland | Lodz | Labieniec-Watala Magdalena |
| Poland | Warsaw | Sek Aleksandra |
| Poland | Warsaw | Dymkowska Dorota |
| Poland | Warsaw | Kampa Rafal Pawel |
| Portugal | Coimbra | Pereira Susana P |
| Portugal | Porto | Beleza Jorge |
| Portugal | Cantanhede | Martins Joao D |
| Portugal | Coimbra | Palmeira Carlos |
| Portugal | Coimbra | Martins Marques T |
| Portugal | Cantanhede | Ferreira LL |
| Portugal | Porto | Coxito Pedro |
| Portugal | Coimbra | Carvalho Eugenia |
| Portugal | Porto | Magalhaes Jose |
| Romania | Timisoara | Lighezan R |
| Romania | Timisoara | Muntean Danina M |
| Singapore | Singapore | Hausenloy Derek J |
| Slovakia | Bratislava | Ukropcova B |
| Slovakia | Bratislava | Maderova D |
| Slovakia | Bratislava | Nemec Michal |
| Slovakia | Bratislava | Ukropec J |
| Slovakia | Bratislava | Sumbalova Zuzana |
| Slovenia | Ljubljana | Pirkmajer Sergej |
| Slovenia | Ljubljana | Dolinar K |
| Slovenia | Ljubljana | Mars T |
| South Africa | Smith James | |
| Spain | Armilla, Granada | Escames Germaine |
| Spain | Barcelona | Gama Perez Pau |
| Spain | A Coruña | Blanco FJ |
| Spain | Barcelona | Batlle M |
| Spain | Armilla (Granada) | Fernandez-Ortiz Marisol |
| Spain | Barcelona | Guitart M |
| Spain | Barcelona | Garcia-Roves Pablo Miguel |
| Spain | Granada | Lopez Garcia Luis Carlos |
| Spain | Madrid | Cadenas S |
| Spain | Madrid | Moran M |
| Spain | Barcelona | Sebastian D |
| Spain | Barcelona | Zorzano Antonio |
| Spain | Barcelona | Catalan M |
| Spain | Armilla (Granada) | Acuna-Castroviejo Dario |
| Spain | Barcelona | De la Torre Lara J |
| Spain | Sevilla | Bustos Matilde |
| Sweden | Stockholm | Cardinale Daniele A |
| Sweden | Linköping | Fontes-Oliveira CC |
| Switzerland | Lausanne | Sandi Carmen |
| Switzerland | Lausanne | Weger M |
| Switzerland | Bern | Nuoffer Jean-Marc |
| Switzerland | Lausanne | Zalachoras I |
| Switzerland | Lausanne | Gebara E |
| Switzerland | Lausanne | Morato Fornaguera L |
| The Netherlands | Wageningen | Van der Ende Miranda |
| The Netherlands | BT Amsterdam | Wuest Rob CI |
| Turkey | Ankara | Tuncay Erkan |
| USA | Little Rock | Porter Craig |
| USA | St Louis | Welch R |
| USA | Gainesville | Wohlgemuth Stephanie E |
| USA | Gainesville | Neyroud D |
| USA | College Station | Latham C |
| USA | Boca Raton | Khamoui Andy V |
| USA | Baton Rouge | Irving Brian A |
| USA | Orlando | Coen Paul M |
| USA | Baton Rouge | Axelrod Christopher L |
| USA | Torrance | Rossiter Harry B |
| USA | Fort Collins | Chicco Adam J |
| USA | Chicago | Dayanidhi Sudarshan |
| USA | Fairbanks | O'Brien Kristin |
| USA | Colorado Springs | Jacobs RA |
| USA | Baltimore | Gonzalez-Freire Marta |
| USA | Norfolk | Lai Nicola |
| USA | Seattle | Marcinek DJ |
| USA | College Station | White-Springer Sarah H |
| USA | Gainesville | Hepple Russell T |
| USA | Baltimore | Fang Evandro F |
| USA | Orlando | Distefano Giovanna |
| USA | Ann Arbor | Beard Daniel A |
| United Kingdom | London | Szabadkai Gyorgy |
| United Kingdom | Manchester | Giakoumaki I |
| United Kingdom | Birmingham | Thakker A |
| United Kingdom | Leeds | Boyle JP |
| United Kingdom | Nottingham | Chakrabarti Lisa |
| United Kingdom | Loughborough | Ebanks Brad |
| United Kingdom | Birmingham | Ashcroft S |
| United Kingdom | Plymouth, Devon | McKenna Helen T |
| United Kingdom | Birmingham | Garten Antje |
| United Kingdom | Oxford | Makrecka-Kuka Marina |
| United Kingdom | Cambridge | Shiroma Jonathan G |
| United Kingdom | Brighton | Moore Anthony L |
| United Kingdom | Birmingham | Joanisse S |
| United Kingdom | Cambridge | Murray Andrew James |
| United States | Providence | Siamwala J |
WG2 Management
Tasks
- Call for participating labs to deliver relevant experimental data on already published studies and to report them in a standardized format.
- Collection and indexing of the data sets as required for statistical analysis.
- Discussion of procedures, protocols and general guidelines.
- Draft a comprehensive review on mt-function in muscle tissue (registration at PROSPERO, link with EQUATOR).
- Opening of the database to the research public for data search and moderated entry of new data sets.
Milestones
- Call for data report delivered.
- Data sets entered in standardized format.
- Summary, interpretation and discussion of data for review.
Deliverables
- A MITOEAGLE database on muscle tissue from humans and model organisms.
- A set of guidelines for future studies on mitochondrial bioenergetics in muscle tissue.
- Draft of review manuscript.
Projects in progress
- » MiPMap
