Acuna-Castroviejo Dario

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COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping


Acuna-Castroviejo Dario


MitoPedia topics: EAGLE 

COST: Member

COST WG2: WG2


COST Mentor: Mentor

MC Substitute - Management Committee MitoEAGLE


Name Acuna-Castroviejo Dario, Professor of Physiology

ORCID ID

Institution
Dario Acuna-Castroviejo

Biomedical Research Center,

Health Science Technology Park,

University of Granada, ES

Address Avenida del Conocimiento, s/n, 18016
City Armilla (Granada)
State/Province
Country Spain
Email [email protected]
Weblink Centro de Investigación Biomédica

http://www.iimel.es/

O2k-Network Lab ES Granada Acuna-Castroviejo D

Bioenergetics Communications

Keywords: melatonin, mitochondria, aging, sepsis, cancer, neurodegeneration/neuroprotection

Participated at


Labels:



Publications

 PublishedReference
BEC 2020.1 doi10.26124bec2020-0001.v12020Gnaiger E et al ― MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1. https://doi.org/10.26124/bec:2020-0001.v1
Chabi 2019 MitoFit Preprint Arch EA2019Chabi BĂ©atrice, Ost M, Gama-Perez P, Dahdah N, Lemieux H, Holody CD, Carpenter RG, Tepp K, Puurand M, Kaambre T, Dubouchaud H, Cortade F, Pesta D, Calabria E, Casado M, Fernandez-Ortiz M, Acuña-Castroviejo D, Villena JA, Grefte S, Keijer J, O'Brien K, Sowton A, Murray AJ, Campbell MD, Marcinek DJ, Nollet E, WĂŒst R, Dayanidhi S, Gnaiger E, Doerrier C, Garcia-Roves PM (2019) Generating reference values on mitochondrial respiration in permeabilized muscle fibers. MitoFit Preprint Arch EA19.1. https://doi.org/10.26124/mitofit:ea19.MitoEAGLE.0001
Lopez 2017 PLOS ONE2017López A, Ortiz F, Doerrier C, Venegas C, Fernåndez-Ortiz M, Aranda P, Díaz-Casado ME, Fernåndez-Gil B, Barriocanal-Casado E, Escames G, López L, Acuña-Castroviejo D (2017) Mitochondrial impairment and melatonin protection in parkinsonian mice do not depend of inducible or neuronal nitric oxide synthases. PLOS ONE 12:e0183090.
Volt 2016 J Pineal Res2016Volt H, García JA, Doerrier C, Díaz-Casado ME, Guerra-Librero A, López LC, Escames G, Tresguerres JA, Acuña-Castroviejo D (2016) Same molecule but different expression: aging and sepsis trigger NLRP3 inflammasome activation, a target of melatonin. J Pineal Res 60:193-205.
Doerrier 2016 Mitochondrion2016Doerrier C, García JA, Volt H, Díaz-Casado ME, Luna-Sånchez M, Fernåndez-Gil B, Escames G, López LC, Acuña-Castroviejo D (2016) Permeabilized myocardial fibers as model to detect mitochondrial dysfunction during sepsis and melatonin effects without disruption of mitochondrial network. Mitochondrion 27:56-63.
Garcia 2015 FASEB J2015GarcĂ­a JA, Volt H, Venegas C, Doerrier C, Escames G, LĂłpez LC, Acuña-Castroviejo D (2015) Disruption of the NF-ÎșB/NLRP3 connection by melatonin requires retinoid-related orphan receptor-α and blocks the septic response in mice. FASEB J 29:3863-75.
García-Corzo 2015 Biochim Biophys Acta2015García-Corzo L, Luna-Sånchez M, Doerrier C, Ortiz F, Escames G, Acuña-Castroviejo D, López LC (2015) Ubiquinol-10 ameliorates mitochondrial encephalopathy associated with CoQ deficiency. Biochim Biophys Acta 1842:893-901.
Ortiz 2015 J Pineal Res2015Ortiz F, Acuña-Castroviejo D, Doerrier C, Dayoub JC, López LC, Venegas C, García JA, López A, Volt H, Luna-Sånchez M, Escames G (2015) Melatonin blunts the mitochondrial/NLRP3 connection and protects against radiation-induced oral mucositis. J Pineal Res 58:34-49.
Ortiz 2014 J Pineal Res2014Ortiz F, García JA, Acuña-Castroviejo D, Doerrier C, López A, Venegas C, Volt H, Luna-Sånchez M, López LC, Escames G (2014) The beneficial effects of melatonin against heart mitochondrial impairment during sepsis: inhibition of iNOS and preservation of nNOS. J Pineal Res 56:71-81.
Doerrier 2014 Life Sci2014Doerrier C, García JA, Volt H, Díaz-Casado ME, Lima-Cabello E, Ortiz F, Luna-Sånchez M, Escames G, López LC, Acuña-Castroviejo D (2014) Identification of mitochondrial deficits and melatonin targets in liver of septic mice by high-resolution respirometry. Life Sci 121:158-65.
Acuña-Castroviejo 2014 Cell Mol Life Sci2014Acuña-Castroviejo D, Escames G, Venegas C, Díaz-Casado ME, Lima-Cabello E, López LC, Rosales-Corral S, Tan DX, Reiter RJ (2014) Extrapineal melatonin: sources, regulation, and potential functions. Cell Mol Life Sci 71:2997-25.
Concepcion-Huertas 2013 J Sports Sci2013Concepcion-Huertas M, Chirosa LJ, De Haro T, Chirosa IJ, Romero V, Aguilar-Martinez D, Leonardo-Mendonça RC, Doerrier C, Escames G, Acuña-Castroviejo D (2013) Changes in the redox status and inflammatory response in handball players during one-year of competition and training. J Sports Sci 31:1197-207.
Escames 2013 Horm Mol Biol Clin Investig2013Escames G, Diaz-Casado ME, Doerrier C, Luna-Sanchez M, Lopez LC, Acuna-Castroviejo D (2013) Early gender differences in the redox status of the brain mitochondria with age: effects of melatonin therapy. Horm Mol Biol Clin Investig 16(2):91-100.
Garcia-Corzo 2013 Hum Mol Genet2013García-Corzo L, Luna-Sånchez M, Doerrier C, García JA, Guarås A, Acín-Pérez R, Bullejos-Peregrín J, López A, Escames G, Enríquez JA, Acuña-Castroviejo D, López LC (2013) Dysfunctional Coq9 protein causes predominant encephalomyopathy associated with CoQ deficiency. Hum Mol Genet 22:1233-48.
Acuña-Castroviejo 2012 Age (Dordr)2012Acuña-Castroviejo D, Carretero M, Doerrier C, López LC, García-Corzo L, Tresguerres JA, Escames G (2012) Melatonin protects lung mitochondria from aging. Age (Dordr) 34(3):681-92.
Acuña-Castroviejo 2011 Curr Top Med Chem2011Acuña-Castroviejo D; López LC; Escames G; López A; García JA; Reiter RJ (2011) Melatonin-mitochondria interplay in health and disease. Curr Top Med Chem 11:221-240.
Lopez 2009 J Pineal Res2009López A, García JA, Escames G, Venegas C, Ortiz F, López LC, Acuña-Castroviejo D (2009) Melatonin protects the mitochondria from oxidative damage reducing oxygen consumption, membrane potential, and superoxide anion production. J Pineal Res 46:188-98.

Abstracts

 PublishedReference
Doerrier 2020 PaduaMuscleDays Poster2020Doerrier C, Gama-Perez P, Chabi B, Ost M, Distefano G, Pesta D, Dahdah N, Lemieux H, Holody C, Carpenter RG, Tepp K, Puurand M, Kaambre T, Dubouchaud H, Cortade F, Calabria E, Casado M, Fernandez-Ortiz M, Acuna-Castroviejo D, Villena JA, Grefte S, Keijer J, O'Brien K, Sowton A, Murray AJ, Campbell MD, Marcinek DJ, Nollet E, Wuest R, Dayanidhi S, Soendergaard SD, Chroeis KM, Gonzalez-Franquesa A, Goodpaster BH, Coen PM, Larsen S, Gnaiger E, Garcia-Roves PM (2020) Commitment to reproducibility in mitochondrial respiration studies with permeabilized muscle fibers. PaduaMuscleDays.
Chabi 2019 MiP20192019
BĂ©atrice Chabi
Generating reference values on mitochondrial respiration in permeabilized muscle fibers.
Garcia-Roves 2019 MiPschool Coimbra2019
Pablo Garcia-Roves
Generating reference values on mitochondrial respiration in permeabilized muscle fibers.
Garcia-Roves 2018 MiP2018b2018
Pablo Garcia-Roves
Generating mitochondrial respirometry reference values from permeabilized mouse soleus muscle fibers. Working Group 2 report. Garcia-Roves_Presentation
Escames 2018 MiP20182018
Germaine Escames
Suppression of AKT/mTOR pathway and activation of mitophagy by melatonin via mitocondrial regulation in head and neck cancer. Escames_Presentation
Acuna-Castroviejo 2018 MiP20182018
Dario Acuna-Castroviejo
Mitochondria, melatonin, and neuroinflammation in Parkinson's disease. Acuna-Castroviejo_Presentation
Doerrier 2014 Abstract SECF2014Evaluation of melatonin treatment in mitochondria of permeabilized myocardial fibers from septic mice.
Luna-SĂĄnchez 2014 Abstract SECF2014Mitochondrial encephalopathy due to coenzyme q deficiency: pathogenesis and treatment.
Volt 2014 Abstract SECF2014Experimental basis for the “inflammaging” theory.
Garcia 2014 Abstract SECF2014Melatonin disrupts the NF-ÎșB/NLRP3 connection in sepsis through RORα receptor.
Diaz-Casado 2014 Abstract SECF2014Melatonin restores mitochondrial regulatory gene expression and function in the zebrafish model of parkinsonism.
Volt 2014 Abstract The 2014 Ageing Summit2014Effects of melatonin on the age-dependent dysregulation of the Nf-Kb/Nlrp3 activation during sepsis.
Ortiz 2013 Abstract SEOR2013Molecular Basis of the radiotherapy-induced mucositis, beneficial effects of melatonin.
Luna-SĂĄnchez 2012 Abstract FEPS&SECF2012CoQ deficiency: Molecular and pathophysiological consequences.
Escames 2012 Abstract ESTRO2012Beneficial effects of topical melatonin against mitochondrial damage during radiotherapy-induced mucositis.
Acuna-Castroviejo 2012 Abstract Bioblast2012Acuna-Castroviejo D (2012) Melatonin and the quality of life: the melatonin-mitochondrion connection. Mitochondr Physiol Network 17.12.
Luna-SĂĄnchez 2012 Abstract MiPsummer School Cambridge2012CoQ deficiency: molecular and phathophysiological consequences.
Doerrier 2012 Abstract Bioblast2012Doerrier C, Garcia JA, Escames G, Acuna-Castroviejo D (2012) Treatment with melatonin prevents myocardial mitochondrial dysfunction in experimental sepsis in mice. Mitochondr Physiol Network 17.12.
Escames 2011 Abstract FASEB Summer Research Conference2011Melatonin regulates the proliferation and differentation of the mice subventricular neural stem cells. Role of mitochondria.
Garcia-Corzo 2011 Abstract Euromit 82011Generation of a mouse model of Coenzyme Q deficiency.
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