Dymkowska Dorota

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COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping


Dymkowska Dorota


MitoPedia topics: EAGLE 

COST: Member COST WG1: WG1 COST WG2: WG2

COST WG4: WG4


Name Dymkowska Dorota, PhD
Institution Laboratory of Cellular Metabolism,

Nencki Institute of Experimental Biology, PL

Address 3 Pasteur Street, 02-093
City Warsaw
State/Province
Country Poland
Email [email protected]
Weblink
O2k-Network Lab PL Warsaw Zablocki K


Labels: Field of research: Basic 



Publications

 PublishedReference
Rydzanicz 2024 EMBO Mol Med2024Rydzanicz M, Kuzniewska B, Magnowska M, Wójtowicz T, Stawikowska A, Hojka A, Borsuk E, Meyza K, Gewartowska O, Gruchota J, Miłek J, Wardaszka P, Chojnicka I, Kondrakiewicz L, Dymkowska D, Puścian A, Knapska E, Dziembowski A, Płoski R, Dziembowska M (2024) Mutation in the mitochondrial chaperone TRAP1 leads to autism with more severe symptoms in males. EMBO Mol Med [Epub ahead of print]. https://doi.org/10.1038/s44321-024-00147-6
BEC 2020.1 doi10.26124bec2020-0001.v12020Gnaiger E et al ― MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1. https://doi.org/10.26124/bec:2020-0001.v1
Dymkowska 2020 J Appl Toxicol2020Dymkowska D, Wrzosek A, Zabłocki K (2020) Atorvastatin and pravastatin stimulate nitric oxide and reactive oxygen species generation, affect mitochondrial network architecture and elevate nicotinamide N-methyltransferase level in endothelial cells. J Appl Toxicol 41:1076-88.
Kawalec 2015 PLoS One2015Kawalec M, Boratyńska-Jasińska A, Beręsewicz M, Dymkowska D, Zabłocki K, Zabłocka B (2015) Mitofusin 2 deficiency affects energy metabolism and mitochondrial biogenesis in MEF cells. PLoS One 10:e0134162.
Schoenfeld 2009 Free Radic Biol Med2009Schönfeld P, Dymkowska D, Wojtczak L (2009) Acyl-CoA-induced generation of reactive oxygen species in mitochondrial preparations is due to the presence of peroxisomes. Free Radic Biol Med 47:503-9.

Abstracts

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MitoEAGLE Short-Term Scientific Mission

Motivation letter
I am employed as an associate professor at the Laboratory of Cellular Metabolism of the Nencki Institute of Experimental Biology. Since many years my scientific interests have been focused on mitochondrial metabolism, in particular concerning changes of their function and structure under conditions associated with a reduced response to insulin and type 2 diabetes. Nowadays thę main goal of my research is to characterize mitochondrial phenotype in human endothelial cells under various pathological conditions. High resolution respirometry techniques are commonly used in my research.
Therefore my participation in the MitoFit Coaching days in Innsbruck would give me an excellent possibility to expand my knowledge of various theoretical and practical aspects concerning an investigation of the mitochondrial energy metabolism. Five days lasting practical training in the MitoFit laboratory will give me an opportunity to work in the best European cęntre of respirometry with true experts in this field. Especially, it would be a great chance to discuss results of my ongoing experiments as well as leam new properly standardized protocols currently accepted in mitochondrial and cellular oxygen consumption assays. Moreover this training will give me a possibility to become acquainted with the newest technical aspects of the use of OROBOROS Oksygraf-zk. I am convinced that my participation in this training will translate into more effective use of respirometry in our study.
Unfortunately, I am not able to cover the total cost of my stay in Innsbruck, thus I would like to apply for a financial support under the MitoEAGLE-COST Action CA15203 (i't Call for STSM Applications) which might make my participation possible.
STSM request: download pdf

Participated at

Visiting scientist in the Oroboros O2k-Laboratory

O2k-Network

Dorota Dymkowska: Visiting scientist at the Oroboros O2k-Laboratory

  • December 12 to 16 2016
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