Semantic search
From Bioblast
Was published in year | Reference | Organism | Tissue;cell | |
---|---|---|---|---|
Civiletto 2018 EMBO Mol Med | 2018 | Civiletto G, Dogan SA, Cerutti R, Fagiolari G, Moggio M, Lamperti C, Benincá C, Viscomi C, Zeviani M (2018) Rapamycin rescues mitochondrial myopathy via coordinated activation of autophagy and lysosomal biogenesis. EMBO Mol Med 10:e8799. | Mouse | Skeletal muscle |
Mayer 2018 Endocrinology | 2018 | Mayer AL, Zhang Y, Feng EH, Higgins CB, Adenekan O, Pietka TA, Beatty WL, DeBosch BJ (2018) Enhanced hepatic PPARα activity links GLUT8 deficiency to augmented peripheral fasting responses in male mice. Endocrinology 159:2110-26. | Mouse | Skeletal muscle Liver |
Kahl 2018 Stroke | 2018 | Kahl A, Stepanova A, Konrad C, Anderson C, Manfredi G, Zhou P, Iadecola C, Galkin A (2018) Critical role of flavin and glutathione in complex I-mediated bioenergetic failure in brain ischemia/reperfusion injury. Stroke 49:1223-31. | Mouse | Nervous system |
Maurya 2018 Cell Rep | 2018 | Maurya SK, Herrera JL, Sahoo SK, Reis FCG, Vega RB, Kelly DP, Periasamy M (2018) Sarcolipin signaling promotes mitochondrial biogenesis and oxidative metabolism in skeletal muscle. Cell Rep 24:2919-31. | Mouse | Skeletal muscle |
Stolf 2018 Biomed Pharmacother | 2018 | Stolf AM, Campos Cardoso C, Morais H, Alves de Souza CE, Lomba LA, Brandt AP, Agnes JP, Collere FC, Galindo CM, Corso CR, Spercoski KM, Locatelli Dittrich R, Zampronio AR, Cadena SMSC, Acco A (2018) Effects of silymarin on angiogenesis and oxidative stress in streptozotocininduced diabetes in mice. Biomed Pharmacother 108:232-43. | Mouse | Liver |
Okerblom 2018 Proc Biol Sci | 2018 | Okerblom J, Fletes W, Patel HH, Schenk S, Varki A, Breen EC (2018) Human-like Cmah inactivation in mice increases running endurance and decreases muscle fatigability: implications for human evolution. Proc Biol Sci 285:20181656. | Mouse | Skeletal muscle |
Tsuda 2018 J Cachexia Sarcopenia Muscle | 2018 | Tsuda M, Fukushima A, Matsumoto J, Takada S, Kakutani N, Nambu H, Yamanashi K, Furihata T, Yokota T, Okita K, Kinugawa S, Anzai T (2018) Protein acetylation in skeletal muscle mitochondria is involved in impaired fatty acid oxidation and exercise intolerance in heart failure. J Cachexia Sarcopenia Muscle 9:844-59. | Mouse | Skeletal muscle |
Jelenik 2018 Diabetes | 2018 | Jelenik T, Flögel U, Álvarez-Hernández E, Scheiber D, Zweck E, Ding Z, Rothe M, Mastrototaro L, Kohlhaas V, Kotzka J, Knebel B, Müller-Wieland D, Moellendorf S, Gödecke A, Kelm M, Westenfeld R, Roden M, Szendroedi J (2018) Insulin resistance and vulnerability to cardiac ischemia. Diabetes 67:2695-702. | Human Mouse | Heart |
Pardo 2018 FASEB J | 2018 | Pardo R, Vilà M, Cervela L, de Marco M, Gama-Pérez P, González-Franquesa A, Statuto L, Vilallonga R, Simó R, Garcia-Roves PM, Villena JA (2018) Calorie restriction prevents diet-induced insulin resistance independently of PGC-1-driven mitochondrial biogenesis in white adipose tissue. FASEB J 33:2343-58. | Mouse | Fat |
Ziegler 2018 Cell | 2018 | Ziegler PK, Bollrath J, Pallangyo CK, Matsutani T, Canli Ö, De Oliveira T, Diamanti MA, Müller N, Gamrekelashvili J, Putoczki T, Horst D, Mankan AK, Öner MG, Müller S, Müller-Höcker J, Kirchner T, Slotta-Huspenina J, Taketo MM, Reinheckel T, Dröse S, Larner AC, Wels WS, Ernst M, Greten TF, Arkan MC, Korn T, Wirth D, Greten FR (2018) Mitophagy in intestinal epithelial cells triggers adaptive immunity during tumorigenesis. Cell 174:88-101. | Mouse | Endothelial;epithelial;mesothelial cell |
Paech 2018a Toxicology | 2018 | Paech F, Mingard C, Grünig D, Abegg VF, Bouitbir J, Krähenbühl S (2018) Mechanisms of mitochondrial toxicity of the kinase inhibitors ponatinib, regorafenib and sorafenib in human hepatic HepG2 cells. Toxicology 395:34-44. | Human Mouse | Liver Other cell lines |
Bytautiene 2018 J Dev Orig Health Dis | 2018 | Bytautiene Prewit E, Porter C, La Rosa M, Bhattarai N, Yin H, Gamble P, Kechichian T, Sidossis LS (2018) Adipose tissue uncoupling protein 1 levels and function are increased in a mouse model of developmental obesity induced by maternal exposure to high-fat diet. J Dev Orig Health Dis 9:401-8. | Mouse | Fat |
Temelie 2018 Oxid Med Cell Longev | 2018 | Temelie M, Savu DI, Moisoi N (2018) Intracellular and intercellular signalling mechanisms following DNA damage are modulated by PINK1. Oxid Med Cell Longev 1391387. | Human Mouse | Nervous system Other cell lines Fibroblast |
Roy Chowdhury 2018 Mol Cell Neurosci | 2018 | Roy Chowdhury S, Djordjevic J, Thomson E, Smith DR, Albensi BC, Fernyhough P (2018) Depressed mitochondrial function and electron transport Complex II-mediated H2O2 production in the cortex of type 1 diabetic rodents. Mol Cell Neurosci 90:49-59. | Mouse Rat | Nervous system |
Bricambert 2018 Nat Commun | 2018 | Bricambert J, Alves-Guerra MC, Esteves P, Prip-Buus C, Bertrand-Michel J, Guillou H, Chang CJ, Vander Wal MN, Canonne-Hergaux F, Mathurin P, Raverdy V, Pattou F, Girard J, Postic C, Dentin R (2018) The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity. Nat Commun 9:2092. | Mouse | Liver |
Wen 2018 PLOS Pathog | 2018 | Wen JJ, Yin YW, Garg NJ (2018) PARP1 depletion improves mitochondrial and heart function in Chagas disease: Effects on POLG dependent mtDNA maintenance. PLOS Pathog 14:e1007065. | Mouse | Heart Other cell lines |
Kauppila 2018 Nucleic Acids Res | 2018 | Kauppila JHK, Bonekamp NA, Mourier A, Isokallio MA, Just A, Kauppila TES, Stewart JB, Larsson NG (2018) Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice. Nucleic Acids Res 46:6642-69. | Mouse | |
Scott 2018 Integr Comp Biol | 2018 | Scott GR, Guo KH, Dawson NJ (2018) The mitochondrial basis for adaptive variation in aerobic performance in high-altitude deer mice. Integr Comp Biol 58:506-18. https://doi.org/10.1093/icb/icy056 | Mouse | Heart Skeletal muscle |
Hughey 2018 J Biol Chem | 2018 | Hughey CC, Trefts E, Bracy DP, James FD, Donahue EP, Wasserman DH (2018) Glycine N-methyltransferase deletion in mice diverts carbon flux from gluconeogenesis to pathways that utilize excess methionine cycle intermediates. J Biol Chem 293:11944-54. | Mouse | Liver |
Goswami 2018 Biophys J | 2018 | Goswami I, Perry JB, Allen ME, Brown DA, von Spakovsky MR, Verbridge SS (2018) Influence of pulsed electric fields and mitochondria-cytoskeleton interactions on cell respiration. Biophys J 114:2951-64. | Mouse | Other cell lines |
Van der Pluijm 2018 Cardiovasc Res | 2018 | van der Pluijm I, Burger J, van Heijningen PM, IJpma A, van Vliet N, Milanese C, Schoonderwoerd K, Sluiter W, Ringuette LJ, Dekkers DHW, Que I, Kaijzel EL, Te Riet L, MacFarlane E, Das D, van der Linden R, Vermeij M, Demmers JA, Mastroberardino PG, Davis EC, Yanagisawa H, Dietz H, Kanaar R, Essers J (2018) Decreased mitochondrial respiration in aneurysmal aortas of Fibulin-4 mutant mice is linked to PGC1A regulation. Cardiovasc Res 114:1776-93. | Mouse | Skeletal muscle |
Musi 2018 Aging Cell | 2018 | Musi N, Valentine JM, Sickora KR, Baeuerle E, Thompson CS, Shen Q, Orr ME (2018) Tau protein aggregation is associated with cellular senescence in the brain. Aging Cell 17:e12840. | Mouse | Nervous system |
Paech 2018b Toxicology | 2018 | Paech F, Abegg VF, Duthaler U, Terracciano L, Bouitbir J, Krähenbühl S (2018) Sunitinib induces hepatocyte mitochondrial damage and apoptosis in mice. Toxicology 409:13-23. | Mouse | Liver |
Klepinin 2018 J Bioenerg Biomembr | 2018 | Klepinin A, Ounpuu L, Mado K, Truu L, Chekulayev V, Puurand M, Shevchuk I, Tepp K, Planken A, Kaambre T (2018) The complexity of mitochondrial outer membrane permeability and VDAC regulation by associated proteins. J Bioenerg Biomembr 50:339-54. | Mouse | Heart Neuroblastoma |
Lu 2018 Cell Rep | 2018 | Lu Z, Cui Y, Wei X, Gao P, Zhang H, Wei X, Li Q, Sun F, Yan Z, Zheng H, Yang G, Liu D, Zhu Z (2018) Deficiency of PKD2L1 (TRPP3) exacerbates pathological cardiac hypertrophy by augmenting NCX1-mediated mitochondrial calcium overload. Cell Rep 24:1639-52. | Mouse | Heart |
Tai 2018 Acta Pharm Sin B | 2018 | Tai Y, Li L, Peng X, Zhu J, Mao X, Qin N, Ma M, Huo R, Bai Y, Dong D (2018) Mitochondrial uncoupler BAM15 inhibits artery constriction and potently activates AMPK in vascular smooth muscle cells. Acta Pharm Sin B 8:909-18. | Mouse | Endothelial;epithelial;mesothelial cell |
Jelenik 2018 Mol Metab | 2018 | Jelenik T, Dille M, Müller-Lühlhoff S, Kabra DG, Zhou Z, Binsch C, Hartwig S, Lehr S, Chadt A, Peters EMJ, Kruse J, Roden M, Al-Hasani H, Castañeda TR (2018) FGF21 regulates insulin sensitivity following long-term chronic stress. Mol Metab 16:126-38. | Mouse | Skeletal muscle |
Sahl 2018 Anal Biochem | 2018 | Sahl RE, Morville T, Kraunsøe R, Dela F, Helge JW, Larsen S (2018) Variation in mitochondrial respiratory capacity and myosin heavy chain composition in repeated muscle biopsies. Anal Biochem 556:119-24. | Human Mouse Saccharomyces cerevisiae | Skeletal muscle |
Khamoui 2018 J Dev Orig Health Dis | 2018 | Khamoui AV, Desai M, Ross MG, Rossiter HB (2018) Sex-specific effects of maternal and postweaning high-fat diet on skeletal muscle mitochondrial respiration. J Dev Orig Health Dis 16:1-8. | Mouse | Skeletal muscle |
Britto 2018 BMC Biol | 2018 | Britto FA, Cortade F, Belloum Y, Blaquière M, Gallot YS, Docquier A, Pagano AF, Jublanc E, Bendridi N, Koechlin-Ramonatxo C, Chabi B, Francaux M, Casas F, Freyssenet D, Rieusset J, Giorgetti-Peraldi S, Carnac G, Ollendorff V, Favier FB (2018) Glucocorticoid-dependent REDD1 expression reduces muscle metabolism to enable adaptation under energetic stress. BMC Biol 16:65. https://doi.org/10.1186/s12915-018-0525-4 | Mouse | Skeletal muscle |
Davila 2018 Elife | 2018 | Davila A, Liu L, Chellappa K, Redpath P, Nakamaru-Ogiso E, Paolella LM, Zhang Z, Migaud ME, Rabinowitz JD, Baur JA (2018) Nicotinamide adenine dinucleotide is transported into mammalian mitochondria. Elife 7:e33246. | Mouse | Skeletal muscle Liver |
Ale-Agha 2018 PLOS Biol | 2018 | Ale-Agha N, Goy C, Jakobs P, Spyridopoulos I, Gonnissen S, Dyballa-Rukes N, Aufenvenne K, von Ameln F, Zurek M, Spannbrucker T, Eckermann O, Jakob S, Gorressen S, Abrams M, Grandoch M, Fischer JW, Köhrer K, Deenen R, Unfried K, Altschmied J, Haendeler J (2018) CDKN1B/p27 is localized in mitochondria and improves respiration-dependent processes in the cardiovascular system - New mode of action for caffeine. PLOS Biol 6:e2004408. | Mouse | Heart |
Farias 2018 Int J Biol Macromol | 2018 | Farias CLA, Martinez GR, Cadena SMSC, Mercê ALR, de Oliveira Petkowicz CL, Noleto GR (2018) Cytotoxicity of xyloglucan from Copaifera langsdorffii and its complex with oxovanadium (IV/V) on B16F10 cells. Int J Biol Macromol 121:1019-28. | Mouse | Endothelial;epithelial;mesothelial cell |
Campbell 2018 Free Radic Biol Med | 2018 | Campbell MD, Duan J, Samuelson AT, Gaffrey MJ, Wang L, Bammler TK, Moore RJ, White CC, Kavanagh TJ, Voss JG, Szeto HH, Rabinovitch PS, Qian WJ, Marcinek DJ (2018) Improving mitochondrial function with SS-31 reverses age-related redox stress and improves exercise tolerance in aged mice. Free Radic Biol Med 134:268-81. | Mouse | Skeletal muscle |
Reutzel 2018 Oxid Med Cell Longev | 2018 | Reutzel M, Grewal R, Silaidos C, Zotzel J, Marx S, Tretzel J, Eckert GP (2018) Effects of long-term treatment with a blend of highly purified olive secoiridoids on cognition and brain ATP levels in aged NMRI mice. Oxid Med Cell Longev 2018:4070935. | Mouse | Nervous system |
Pape 2018 Nutrients | 2018 | Pape JA, Newey CR, Burrell HR, Workman A, Perry K, Bikman BT, Bridgewater LC, Grose JH (2018) Per-Arnt-Sim kinase (PASK) deficiency increases cellular respiration on a standard diet and decreases liver triglyceride accumulation on a western high-fat high-sugar diet. Nutrients 10:1990. | Mouse | Skeletal muscle Liver |
Kauppila 2018 Thesis | 2018 | Kauppila JHK (2018) Generating mammalian mitochondrial disease models with mitochondrial DNA mutations. PhD Thesis p120. | Mouse | Heart Liver |
Singh 2018 Arch Toxicol | 2018 | Singh F, Zoll J, Duthaler U, Charles AL, Panajatovic MV, Laverny G, McWilliams TG, Metzger D, Geny B, Krähenbühl S, Bouitbir J (2018) PGC-1β modulates statin-associated myotoxicity in mice. Arch Toxicol 93:487-504. | Mouse | Skeletal muscle |
Davis 2018 FASEB J | 2018 | Davis RAH, Deemer SE, Bergeron JM, Little JT, Warren JL, Fisher G, Smith DL Jr, Fontaine KR, Dickinson SL, Allison DB, Plaisance EP (2018) Dietary R, S-1,3-butanediol diacetoacetate reduces body weight and adiposity in obese mice fed a high-fat diet. FASEB J 33:2409-21. | Mouse | Skeletal muscle |
De Lima Junior 2018 EBioMedicine | 2018 | De Lima Junior JC, Souza GF, Moura-Assis A, Gaspar RS, Gaspar JM, Rocha AL, Ferrucci DL, Lima TI, Victório SC, Bonfante ILP, Cavaglieri CR, Pareja JC, Brunetto SQ, Ramos CD, Geloneze B, Mori MA, Silveira LR, Segundo GRS, Ropelle ER, Velloso LA (2018) Abnormal brown adipose tissue mitochondrial structure and function in IL10 deficiency. EBioMedicine 39:436-47. | Mouse | Fat |
Brunetta 2018 Exp Physiol | 2018 | Brunetta HS, de Paula GC, de Oliveira J, Martins EL, Dos Santos GJ, Filho AG, Rafacho A, de Bem AF, Nunes EA (2018) Decrement in resting and insulin-stimulated soleus muscle mitochondrial respiration is an early event in diet-induced obesity in mice. Exp Physiol 104:306-21. | Mouse | Skeletal muscle |
Eimre 2018 Oxid Med Cell Longev | 2018 | Eimre M, Paju K, Peet N, Kadaja L, Tarrend M, Kasvandik S, Seppet J, Ivask M, Orlova E, Kõks S (2018) Increased mitochondrial protein levels and bioenergetics in the musculus rectus femoris of Wfs1-deficient mice. Oxid Med Cell Longev 2018:3175313. | Mouse | Skeletal muscle |
McLaughlin 2018 Biochem Biophys Res Commun | 2018 | McLaughlin KL, McClung JM, Fisher-Wellman KH (2018) Bioenergetic consequences of compromised mitochondrial DNA repair in the mouse heart. Biochem Biophys Res Commun 504:742-48. | Mouse | Heart |
MacMillan-Crow 2018 Intern Med Rev (Wash D C) | 2018 | MacMillan-Crow LA, Mayeux PR (2018) Female mice exhibit less renal mitochondrial injury but greater mortality using a comorbid model of experimental sepsis. Intern Med Rev (Wash D C) 4. | Mouse | Kidney |
Hancock 2018 Elife | 2018 | Hancock M, Hafstad AD, Nabeebaccus AA, Catibog N, Logan A, Smyrnias I, Hansen SS, Lanner J, Schröder K, Murphy MP, Shah AM, Zhang M (2018) Myocardial NADPH oxidase-4 regulates the physiological response to acute exercise. Elife 7:e41044. | Mouse | Heart |
D'Souza 2018 J Lipid Res | 2018 | D'Souza K, Nzirorera C, Cowie AM, Varghese GP, Trivedi P, Eichmann TO, Biswas D, Touaibia M, Morris AJ, Aidinis V, Kane DA, Pulinilkunnil T, Kienesberger PC (2018) Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism. J Lipid Res 59:1805-17. | Mouse | Skeletal muscle |
Giordano 2018 Am J Respir Cell Mol Biol | 2018 | Giordano L, Farnham A, Dhandapani PK, Salminen L, Bhaskaran J, Voswinckel R, Rauschkolb P, Scheibe S, Sommer N, Beisswenger C, Weissmann N, Braun T, Jacobs HT, Bals R, Herr C, Szibor M (2018) Alternative oxidase attenuates cigarette smoke-induced lung dysfunction and tissue damage. Am J Respir Cell Mol Biol 60:515-22. | Mouse | Fibroblast |
Reguis Yadao 2018 Thesis | 2018 | Reguis Yadao DR (2018) Smooth muscle cell mitochondrial respiration – effects of aerobic training and type I diabetes. Master's Thesis 71. | Mouse | Other cell lines |
Urazov 2018 Sovrem Tekhnologii Med | 2018 | Urazov MD, Astrakhanova TA, Usenko AV, Mishchenko TA, Schelchkova NA, Kravchenko GA, Vedunova MV, Mitroshina EV (2018) New aspects of central nervous system adaptation to prenatal hypoxia. Sovrem Tekhnologii Med 10:60-68. | Mouse | Nervous system |
Astrakhanova 2018 Sovrem Tekhnologii Med | 2018 | Astrakhanova ТА, Urazov МD, Usenko АV, Mitroshina ЕV, Mishchenko ТА, Schelchkova NА, Vedunova МV (2018) BDNF-mediated regulation of the brain mitochondria functional state in hypoxia. Sovrem Tekhnologii Med 10:88-94. | Mouse | Nervous system |
Torres 2018 Cell Metab | 2018 | Torres MJ, Kew KA, Ryan TE, Pennington ER, Lin CT, Buddo KA, Fix AM, Smith CA, Gilliam LA, Karvinen S, Lowe DA, Spangenburg EE, Zeczycki TN, Shaikh SR, Neufer PD (2018) 17β-estradiol directly lowers mitochondrial membrane microviscosity and improves bioenergetic function in skeletal muscle. Cell Metab 27:167-79. https://doi.org/10.1016/j.cmet.2017.10.003 | Mouse | Skeletal muscle |
Siira 2018 EMBO Rep | 2018 | Siira SJ, Rossetti G, Richman TR, Perks K, Ermer JA, Kuznetsova I, Hughes L, Shearwood AJ, Viola HM, Hool LC, Rackham O, Filipovska A (2018) Concerted regulation of mitochondrial and nuclear non-coding RNAs by a dual-targeted RNase Z. EMBO Rep 19:e46198. | Mouse | Heart |
Stepanova 2018 J Neurochem | 2018 | Stepanova A, Konrad C, Manfredi G, Springett R, Ten V, Galkin A (2018) The dependence of brain mitochondria reactive oxygen species production on oxygen level is linear, except when inhibited by antimycin A. J Neurochem 148:731-45. | Mouse | Nervous system |
Matsumoto 2018 Circulation | 2018 | Matsumoto J, Takada S, Kinugawa S, Furihata T, Nambu H, Kakutani N, Tsuda M, Fukushima A, Yokota T, Tanaka S, Takahashi H, Watanabe M, Hatakeyama S, Matsumoto M, Nakayama KI, Otsuka Y, Sabe H, Tsutsui H, Anzai T (2018) Brain-derived neurotrophic factor improves limited exercise capacity in mice with heart failure. Circulation 138:2064-66. | Mouse | Skeletal muscle |
Burstein 2018 Hum Mol Genet | 2018 | Burstein SR, Valsecchi F, Kawamata H, Bourens M, Zeng R, Zuberi A, Milner TA, Cloonan SM, Lutz C, Barrientos A, Manfredi G (2018) In vitro and in vivo studies of the ALS-FTLD protein CHCHD10 reveal novel mitochondrial topology and protein interactions. Hum Mol Genet 27:160-77. | Human Mouse | Heart Skeletal muscle Nervous system HEK |
Fink 2018 J Biol Chem | 2018 | Fink BD, Bai F, Yu L, Sheldon RD, Sharma A, Taylor EB, Sivitz WI (2018) Oxaloacetic acid mediates ADP-dependent inhibition of mitochondrial complex II-driven respiration. J Biol Chem 293:19932-41. https://doi.org/10.1074/jbc.RA118.005144 | Mouse | Skeletal muscle |
Van Den Brink 2018 PLoS Genet | 2018 | Van Den Brink DM, Cubizolle A, Chatelain G, Davoust N, Girard V, Johansen S, Napoletano F, Dourlen P, Guillou L, Angebault-Prouteau C, Bernoud-Hubac N, Guichardant M, Brabet P, Mollereau B (2018) Physiological and pathological roles of FATP-mediated lipid droplets in Drosophila and mice retina. PLoS Genet 14:e1007627. | Mouse | Endothelial;epithelial;mesothelial cell |
Rocha 2018 J Physiol Biochem | 2018 | Rocha C, Koury OH, Scheede-Bergdahl C, Bergdahl A (2018) Cardiac mitochondrial respiration following a low-carbohydrate, high-fat diet in apolipoprotein E-deficient mice. J Physiol Biochem 75:65-72. | Mouse | Heart |
Arnoux 2018 Elife | 2018 | Arnoux I, Willam M, Griesche N, Krummeich J, Watari H, Offermann N, Weber S, Narayan Dey P, Chen C, Monteiro O, Buettner S, Meyer K, Bano D, Radyushkin K, Langston R, Lambert JJ, Wanker E, Methner A, Krauss S, Schweiger S, Stroh A (2018) Metformin reverses early cortical network dysfunction and behavior changes in Huntington's disease. Elife 7:e38744. | Mouse | Nervous system |
Cronin 2018 Nature | 2018 | Cronin SJF, Seehus C, Weidinger A, Talbot S, Reissig S, Seifert M, Pierson Y, McNeill E, Longhi MS, Turnes BL, Kreslavsky T, Kogler M, Hoffmann D, Ticevic M, da Luz Scheffer D, Tortola L, Cikes D, Jais A, Rangachari M, Rao S, Paolino M, Novatchkova M, Aichinger M, Barrett L, Latremoliere A, Wirnsberger G, Lametschwandtner G, Busslinger M, Zicha S, Latini A, Robson SC, Waisman A, Andrews N, Costigan M, Channon KM, Weiss G, Kozlov AV, Tebbe M, Johnsson K, Woolf CJ, Penninger JM (2018) The metabolite BH4 controls T cell proliferation in autoimmunity and cancer. Nature 563:564-68. | Mouse | Lymphocyte |
Sprenger 2018 EMBO Mol Med | 2018 | Sprenger HG, Wani G, Hesseling A, König T, Patron M, MacVicar T, Ahola S, Wai T, Barth E, Rugarli EI, Bergami M, Langer T (2018) Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy. EMBO Mol Med 11:e9288. | Mouse | Nervous system |
Laouafa 2018 Adv Exp Med Biol | 2018 | Laouafa S, Roussel D, Marcouiller F, Soliz J, Bairam A, Joseph V (2018) Role of estradiol receptor beta (ERβ) on arterial pressure, respiratory chemoreflex and mitochondrial function in young and aged female mice. Adv Exp Med Biol 1071:115-27. | Mouse | Nervous system |
Takahashi 2018 Sci Rep | 2018 | Takahashi K, Miura Y, Ohsawa I, Shirasawa T, Takahashi M (2018) In vitro rejuvenation of brain mitochondria by the inhibition of actin polymerization. Sci Rep 8:15585. | Mouse | Nervous system |
McWilliams 2018 Open Biol | 2018 | McWilliams TG, Barini E, Pohjolan-Pirhonen R, Brooks SP, Singh F, Burel S, Balk K, Kumar A, Montava-Garriga L, Prescott AR, Hassoun SM, Mouton-Liger F, Ball G, Hills R, Knebel A, Ulusoy A, Di Monte DA, Tamjar J, Antico O, Fears K, Smith L, Brambilla R, Palin E, Valori M, Eerola-Rautio J, Tienari P, Corti O, Dunnett SB, Ganley IG, Suomalainen A, Muqit MMK (2018) Phosphorylation of Parkin at serine 65 is essential for its activation in vivo. Open Biol 8:180108. | Mouse | Nervous system |
Vinel 2018 Nat Med | 2018 | Vinel C, Lukjanenko L, Batut A, Deleruyelle S, Pradere JP, Le Gonidec S, Dortignac A, Geoffre N, Pereira O, Karaz S, Lee U, Camus M, Chaoui K, Mouisel E, Bigot A, Mouly V, Vigneau M, Pagano AF, Chopard A, Pillard F, Guyonnet S, Cesari M, Burlet-Schiltz O, Pahor M, Feige JN, Vellas B, Valet P, Dray C (2018) The exerkine apelin reverses age-associated sarcopenia. Nat Med 24:1360-71. | Mouse | Skeletal muscle |
Fisher-Wellman 2018 Cell Rep | 2018 | Fisher-Wellman KH, Davidson MT, Narowski TM, Lin CT, Koves TR, Muoio DM (2018) Mitochondrial diagnostics: A multiplexed assay platform for comprehensive assessment of mitochondrial energy fluxes. Cell Rep 24:3593-606. | Mouse | Heart Skeletal muscle |
Francisco 2018 J Neurochem | 2018 | Francisco A, Ronchi JA, Navarro CDC, Figueira TR, Castilho RF (2018) Nicotinamide nucleotide transhydrogenase is required for brain mitochondrial redox balance under hampered energy substrate metabolism and high-fat diet. J Neurochem 147:663-77. | Mouse | Nervous system |
Quispe 2018 Redox Biol | 2018 | Quispe RL, Jaramillo ML, Galant LS, Engel D, Dafre AL, Teixeira da Rocha JB, Radi R, Farina M, de Bem AF (2018) Diphenyl diselenide protects neuronal cells against oxidative stress and mitochondrial dysfunction: Involvement of the glutathione-dependent antioxidant system. Redox Biol 20:118-29. | Mouse | Nervous system Other cell lines |
Kleszczynski 2018 Int J Mol Sci | 2018 | Kleszczyński K, Bilska B, Stegemann A, Flis DJ, Ziolkowski W, Pyza E, Luger TA, Reiter RJ, Böhm M, Slominski AT (2018) Melatonin and its metabolites ameliorate UVR-induced mitochondrial oxidative stress in human MNT-1 melanoma cells. Int J Mol Sci 19:E3786. | Mouse | Liver |
Wilmanns 2018 Mol Metab | 2018 | Wilmanns JC, Pandey R, Hon O, Chandran A, Schilling JM, Forte E, Wu Q, Cagnone G, Bais P, Philip V, Coleman D, Kocalis H, Archer SK, Pearson JT, Ramialison M, Heineke J, Patel HH, Rosenthal NA, Furtado MB, Costa MW (2018) Metformin intervention prevents cardiac dysfunction in a murine model of adult congenital heart disease. Mol Metab 20:102-14. | Mouse | Heart |
Harmuth 2018 Front Mol Neurosci | 2018 | Harmuth T, Prell-Schicker C, Weber JJ, Gellerich F, Funke C, Drießen S, Magg JCD, Krebiehl G, Wolburg H, Hayer SN, Hauser S, Krüger R, Schöls L, Riess O, Hübener-Schmid J (2018) Mitochondrial morphology, function and homeostasis are impaired by expression of an N-terminal calpain cleavage fragment of Ataxin-3. Front Mol Neurosci 11:368. | Mouse | Fibroblast |
Tyagi 2018 Sci Rep | 2018 | Tyagi A, Nguyen CU, Chong T, Michel CR, Fritz KS, Reisdorph N, Knaub L, Reusch JEB, Pugazhenthi S (2018) SIRT3 deficiency-induced mitochondrial dysfunction and inflammasome formation in the brain. Sci Rep 8:17547. | Mouse | Nervous system |
Park 2018 J Clin Invest | 2018 | Park H, He A, Tan M, Johnson JM, Dean JM, Pietka TA, Chen Y, Zhang X, Hsu FF, Razani B, Funai K, Lodhi IJ (2018) Peroxisome-derived lipids regulate adipose thermogenesis by mediating cold-induced mitochondrial fission. J Clin Invest 129:694-711. | Mouse | Fat |
Valentine 2018 J Gerontol A Biol Sci Med Sci | 2018 | Valentine JM, Li ME, Shoelson SE, Zhang N, Reddick RL, Musi N (2018) NFκB regulates muscle development and mitochondrial function. J Gerontol A Biol Sci Med Sci 75:647-53. | Mouse | Skeletal muscle |
Pamenter 2018 PLoS One | 2018 | Pamenter ME, Lau GY, Richards JG (2018) Effects of cold on murine brain mitochondrial function. PLoS One 13:e0208453. | Mouse | Nervous system |
Menezes-Filho 2018 Biochim Biophys Acta Bioenerg | 2018 | Menezes-Filho SL, Amigo I, Luévano-Martínez LA, Kowaltowski AJ (2018) Fasting promotes functional changes in liver mitochondria. Biochim Biophys Acta Bioenerg 1860:129-35. | Mouse | Liver |
Rudnicki 2018 Elife | 2018 | Rudnicki M, Abdifarkosh G, Nwadozi E, Ramos SV, Makki A, Sepa-Kishi DM, Ceddia RB, Perry CG, Roudier E, Haas TL (2018) Endothelial-specific FoxO1 depletion prevents obesity-related disorders by increasing vascular metabolism and growth. Elife 7:e39780. | Mouse | Fat |
Logan 2018 Mol Metab | 2018 | Logan S, Pharaoh GA, Marlin MC, Masser DR, Matsuzaki S, Wronowski B, Yeganeh A, Parks EE, Premkumar P, Farley JA, Owen DB, Humphries KM, Kinter M, Freeman WM, Szweda LI, Van Remmen H, Sonntag WE (2018) Insulin-like growth factor receptor signaling regulates working memory, mitochondrial metabolism, and amyloid-β uptake in astrocytes. Mol Metab 9:141-55. | Mouse | Nervous system |
Zimin 2018 Br J Anaesth | 2018 | Zimin PI, Woods CB, Kayser EB, Ramirez JM, Morgan PG, Sedensky MM (2018) Isoflurane disrupts excitatory neurotransmitter dynamics via inhibition of mitochondrial complex I. Br J Anaesth 120:1019-32. | Mouse | Nervous system |
Zhuang 2018 Thesis | 2018 | Zhuang Y (2018) Potential application of alternative oxidase (AOX) in neurodegenerative diseases. Master's Thesis p71. | Mouse | Nervous system |
Corrochano 2018 Hum Mol Genet | 2018 | Corrochano S, Blanco G, Williams D, Wettstein J, Simon M, Kumar S, Moir L, Agnew T, Stewart M, Landman A, Kotiadis VN, Duchen MR, Wackerhage H, Rubinsztein DC, Brown SDM, Acevedo-Arozena A (2018) A genetic modifier suggests that endurance exercise exacerbates Huntington's disease. Hum Mol Genet 27:1723-31. | Mouse | Skeletal muscle |
Friederich-Persson 2018 Acta Physiol (Oxf) | 2018 | Friederich-Persson M, Persson P, Hansell P, Palm F (2018) Deletion of Uncoupling Protein-2 reduces renal mitochondrial leak respiration, intrarenal hypoxia and proteinuria in a mouse model of type 1 diabetes. Acta Physiol (Oxf) 223:e13058. | Mouse | Kidney |
Machado-Neto 2018 Cell Death Dis | 2018 | Machado-Neto JA, Fenerich BA, Scopim-Ribeiro R, Eide CA, Coelho-Silva JL, Dechandt CRP, Fernandes JC, Rodrigues Alves APN, Scheucher PS, Simões BP, Alberici LC, de Figueiredo Pontes LL, Tognon CE, Druker BJ, Rego EM, Traina F (2018) Metformin exerts multitarget antileukemia activity in JAK2V617F-positive myeloproliferative neoplasms. Cell Death Dis 9:311. | Human Mouse | Other cell lines |
Quispe 2018 Mol Neurobiol | 2018 | Quispe RL, Canto RFS, Jaramillo ML, Barbosa FAR, Braga AL, de Bem AF, Farina M (2018) Design, synthesis, and in vitro evaluation of a novel probucol derivative: protective activity in neuronal cells through GPx upregulation. Mol Neurobiol 55:7619-34. | Mouse | Nervous system Other cell lines |
Lica 2018 Stem Cells Dev | 2018 | Lica JJ, Grabe GJ, Heldt M, Misiak M, Bloch P, Serocki M, Switalska M, Wietrzyk J, Baginski M, Hellmann A, Borowski E, Skladanowski A (2018) Cell density-dependent cytological stage profile and its application for a screen of cytostatic agents active towards Leukemic Stem Cells. Stem Cells Dev 27:488-513. | Human Mouse | Heart Blood cells Other cell lines |
Doerrier 2018 Methods Mol Biol | 2018 | Doerrier C, Garcia-Souza LF, Krumschnabel G, Wohlfarter Y, Mészáros AT, Gnaiger E (2018) High-Resolution FluoRespirometry and OXPHOS protocols for human cells, permeabilized fibers from small biopsies of muscle, and isolated mitochondria. Methods Mol Biol 1782:31-70. https://doi.org/10.1007/978-1-4939-7831-1_3 | Human Mouse Rat Saccharomyces cerevisiae | Heart Skeletal muscle Endothelial;epithelial;mesothelial cell Blood cells HEK Platelet |
Qin 2018 Biochem Biophys Res Commun | 2018 | Qin Q, Jin J, He F, Zheng Y, Li T, Zhang Y, He J (2018) Humanin promotes mitochondrial biogenesis in pancreatic MIN6 β-cells. Biochem Biophys Res Commun 497:292-7. | Mouse | Islet cell;pancreas;thymus Other cell lines |
Coleman 2018 Sci Rep | 2018 | Coleman V, Sa-Nguanmoo P, Koenig J, Schulz TJ, Grune T, Klaus S, Kipp AP, Ost M (2018) Partial involvement of Nrf2 in skeletal muscle mitohormesis as an adaptive response to mitochondrial uncoupling. Sci Rep 8:2446. | Mouse | Skeletal muscle |
Rubio-Villena 2018 Hum Mol Genet | 2018 | Rubio-Villena C, Viana R, Bonet J, Garcia-Gimeno MA, Casado M, Heredia M, Sanz P (2018) Astrocytes: new players in progressive myoclonus epilepsy of Lafora type. Hum Mol Genet 27:1290-1300. | Mouse | Nervous system |
Yang 2018 Cell Death Dis | 2018 | Yang F, Wu R, Jiang Z, Chen J, Nan J, Su S, Zhang N, Wang C, Zhao J, Ni C, Wang Y, Hu W, Zeng Z, Zhu K, Liu X, Hu X, Zhu W, Yu H, Huang J, Wang J (2018) Leptin increases mitochondrial OPA1 via GSK3-mediated OMA1 ubiquitination to enhance therapeutic effects of mesenchymal stem cell transplantation. Cell Death Dis 9:556. | Mouse | |
Bhaskaran 2018 EMBO Rep | 2018 | Bhaskaran S, Pharaoh G, Ranjit R, Murphy A, Matsuzaki S, Nair BC, Forbes B, Gispert S, Auburger G, Humphries KM, Kinter M, Griffin TM, Deepa SS (2018) Loss of mitochondrial protease ClpP protects mice from diet-induced obesity and insulin resistance. EMBO Rep 19. pii: e45009. | Mouse | Fat |
Ravasz 2018 Biochim Biophys Acta | 2018 | Ravasz D, Kacso G, Fodor V, Horvath K, Adam-Vizi V, Chinopoulos C (2018) Reduction of 2-methoxy-1,4-naphtoquinone by mitochondrially-localized Nqo1 yielding NAD+ supports substrate-level phosphorylation during respiratory inhibition. Biochim Biophys Acta 1859:909-24. | Mouse | Liver |
Collard 2018 Mol Cell Biol | 2018 | Collard R, Majtan T, Park I, Kraus JP (2018) Import of TAT-conjugated propionyl coenzyme A carboxylase using models of propionic acidemia. Mol Cell Biol 38. pii: e00491-17. | Mouse | Liver |
Bjoerndal 2018 Nutr Metab (Lond) | 2018 | Bjørndal B, Alterås EK, Lindquist C, Svardal A, Skorve J, Berge RK (2018) Associations between fatty acid oxidation, hepatic mitochondrial function, and plasma acylcarnitine levels in mice. Nutr Metab (Lond) 15:10. | Mouse | Liver |
Schilperoort 2018 EMBO Mol Med | 2018 | Schilperoort M, van Dam AD, Hoeke G, Shabalina IG, Okolo A, Hanyaloglu AC, Dib LH, Mol IM, Caengprasath N, Chan YW, Damak S, Miller AR, Coskun T, Shimpukade B, Ulven T, Kooijman S, Rensen PC, Christian M (2018) The GPR120 agonist TUG-891 promotes metabolic health by stimulating mitochondrial respiration in brown fat. EMBO Mol Med 10:e8047. | Mouse | Fat |
Mancini 2017 Thesis | 2018 | Mancini G (2017) Colesterol dietético e doença de Alzheimer em modelos experimentais: avaliação da resposta sináptica, mitocondrial e comportamental. Doctoral Thesis p118. | Mouse | Nervous system |
Velazquez-Villegas 2018 Nat Commun | 2018 | Velazquez-Villegas LA, Perino A, Lemos V, Zietak M, Nomura M, Pols TWH, Schoonjans K (2018) TGR5 signalling promotes mitochondrial fission and beige remodelling of white adipose tissue. Nat Commun 9:245. | Mouse | Fat |
Setz 2018 Hear Res | 2018 | Setz C, Benischke AS, Pinho Ferreira Bento AC, Brand Y, Levano S, Paech F, Leitmeyer K, Bodmer D (2018) Induction of mitophagy in the HEI-OC1 auditory cell line and activation of the Atg12/LC3 pathway in the organ of Corti. Hear Res 361:52-65. | Mouse | Other cell lines |
Wu 2018 Adv Sci | 2018 | Wu S, Zhang A, Li S, Chatterjee S, Qi R, Segura-Ibarra V, Ferrari M, Gupte A, Blanco E, Hamilton DJ (2018) Polymer functionalization of isolated mitochondria for cellular transplantation and metabolic phenotype alteration. Adv Sci 1700530. | Mouse | Liver |
Treberg 2018 Comp Biochem Physiol B Biochem Mol Biol | 2018 | Treberg JR, Braun K, Zacharias P, Kroeker K (2018) Multidimensional mitochondrial energetics: Application to the study of electron leak and hydrogen peroxide metabolism. Comp Biochem Physiol B Biochem Mol Biol 224:121-28. | Mouse Rat | Skeletal muscle |