Semantic search
From Bioblast
Year | Reference | Organism | Tissue;cell | Tissue and cell | |
---|---|---|---|---|---|
Belosludtsev 2018 Biochim Biophys Acta | 2018 | Belosludtsev KN, Belosludtseva NV, Talanov EY, Tenkov KS, Starinets VS, Agafonov AV, Pavlik LL, Dubinin MV (2018) Effect of bedaquiline on the functions of rat liver mitochondria. Biochim Biophys Acta 1861:288-97. | Rat | Liver | Liver |
Nacarelli 2018 Geroscience | 2018 | Nacarelli T, Azar A, Altinok O, Orynbayeva Z, Sell C (2018) Rapamycin increases oxidative metabolism and enhances metabolic flexibility in human cardiac fibroblasts. Geroscience 40:243-56. | Human | Heart Fibroblast | Heart Fibroblast |
Hecker 2018 Biochim Biophys Acta | 2018 | Hecker M, Sommer N, Foch S, Hecker A, Hackstein H, Witzenrath M, Weissmann N, Seeger W, Mayer K (2018) Resolvin E1 and its precursor 18R-HEPE restore mitochondrial function in inflammation. Biochim Biophys Acta 1863:1016-28. | Human | Blood cells | Blood cells |
Cecatto 2018 J Cell Biochem | 2018 | Cecatto C, Wajner A, Vargas CR, Wajner SM, Amaral AU, Wajner M (2018) High vulnerability of the heart and liver to 3-hydroxypalmitic acid-induced disruption of mitochondrial functions in intact cell systems. J Cell Biochem 119:7678-86. | Rat | Heart Nervous system Liver | Heart Nervous system Liver |
Paech 2018b Toxicology | 2018 | Paech F, Abegg VF, Duthaler U, Terracciano L, Bouitbir J, Krähenbühl S (2018) Sunitinib induces hepatocyte mitochondrial damage and apoptosis in mice. Toxicology 409:13-23. | Mouse | Liver | Liver |
Remor 2018 Mol Neurobiol | 2018 | Remor AP, da Silva RA, de Matos FJ, Glaser V, de Paula Martins R, Ghisoni K, da Luz Scheffer D, Andia DC, Portinho D, de Souza AP, de Oliveira PA, Prediger RD, Torres AI, Linhares RMM, Walz R, Ronsoni MF, Hohl A, Rafacho A, Aguiar AS Jr, De Paul AL, Latini A (2018) Chronic metabolic derangement-induced cognitive deficits and neurotoxicity are associated with REST inactivation. Mol Neurobiol 56:1539-57. | Rat | Nervous system | Nervous system |
Piel 2018 Intensive Care Med Exp | 2018 | Piel S, Ehinger JK, Chamkha I, Frostner EÅ, Sjövall F, Elmér E, Hansson MJ (2018) Bioenergetic bypass using cell-permeable succinate, but not methylene blue, attenuates metformin-induced lactate production. Intensive Care Med Exp 6:22. | Human | Platelet Blood cells | Platelet Blood cells |
Gao 2018 Free Radic Biol Med | 2018 | Gao JL, Zhao J, Zhu HB, Peng X, Zhu JX, Ma MH, Fu Y, Hu N, Tai Y, Xuan XC, Dong DL (2018) Characterizations of mitochondrial uncoupling induced by chemical mitochondrial uncouplers in cardiomyocytes. Free Radic Biol Med 124:288-98. | Rat | Heart | Heart |
Tai 2018 Acta Pharm Sin B | 2018 | Tai Y, Li L, Peng X, Zhu J, Mao X, Qin N, Ma M, Huo R, Bai Y, Dong D (2018) Mitochondrial uncoupler BAM15 inhibits artery constriction and potently activates AMPK in vascular smooth muscle cells. Acta Pharm Sin B 8:909-18. | Mouse | Endothelial;epithelial;mesothelial cell | Endothelial;epithelial;mesothelial cell |
Rundle 2018 Environ Sci Technol | 2018 | Rundle K, Sharaf M, Stevens D, Kamunde C, Van Den Heuvel MR (2018) Oil sands-derived naphthenic acids are oxidative uncouplers and impair electron transport in isolated mitochondria. Environ Sci Technol 52:10803-11. | Fishes | Liver | Liver |
Haegler 2017 PLOS ONE | 2017 | Haegler P, Grünig D, Berger B, Terracciano L, Krähenbühl S, Bouitbir J (2017) Hepatic effects of pharmacological doses of hydroxy-cobalamin[c-lactam] in mice. PLOS ONE 12:e0171026. | Mouse | Liver | Liver |
Cunha de Padua 2017 Carbohydr Polym | 2017 | Cunha de Padua MM, Suter Correia Cadena SM, de Oliveira Petkowicz CL, Martinez GR, Rodrigues Noleto G (2017) Toxicity of native and oxovanadium (IV/V) galactomannan complexes on HepG2 cells is related to impairment of mitochondrial functions. Carbohydr Polym 173:665-75. | Human | Liver | Liver |
Most 2017 Eur J Clin Nutr | 2017 | Most J, Penders J, Lucchesi M, Goossens GH, Blaak EE (2017) Gut microbiota composition in relation to the metabolic response to 12-week combined polyphenol supplementation in overweight men and women. Eur J Clin Nutr 71:1040-5. | Human | Skeletal muscle | Skeletal muscle |
Yeh 2017 Aquat Toxicol | 2017 | Yeh A, Marcinek DJ, Meador JP, Gallagher EP (2017) Effect of contaminants of emerging concern on liver mitochondrial function in Chinook salmon. Aquat Toxicol 190:21-31. | Fishes | Liver | Liver |
Asping 2017 Eur J Clin Pharmacol | 2017 | Asping M, Stride N, Søgaard D, Dohlmann TL, Helge JW, Dela F, Larsen S (2017) The effects of 2 weeks of statin treatment on mitochondrial respiratory capacity in middle-aged males: the LIFESTAT study. Eur J Clin Pharmacol 73:679-87. | Human | ||
Calcutt 2017 J Clin Invest | 2017 | Calcutt NA, Smith DR, Frizzi K, Sabbir MG, Chowdhury SK, Mixcoatl-Zecuatl T, Saleh A, Muttalib N, Van der Ploeg R, Ochoa J, Gopaul A, Tessler L, Wess J, Jolivalt CG, Fernyhough P (2017) Selective antagonism of muscarinic receptors is neuroprotective in peripheral neuropathy. J Clin Invest 127:608-22. | Rat | Nervous system | Nervous system |
Cardoso 2017 Biochim Biophys Acta | 2017 | Cardoso GMF, Pletsch JT, Parmeggiani B, Grings M, Glanzel NM, Bobermin LD, Amaral AU, Wajner M, Leipnitz G (2017) Bioenergetics dysfunction, mitochondrial permeability transition pore opening and lipid peroxidation induced by hydrogen sulfide as relevant pathomechanisms underlying the neurological dysfunction characteristic of ethylmalonic encephalopathy. Biochim Biophys Acta 1863:2192-2201. | Rat | Nervous system | Nervous system |
Sidlauskas 2017 Neurosci Lett | 2017 | Sidlauskas K, Sidlauskiene R, Li N, Liobikas J (2017) 5-Hydroxy-1,4-naphthalenedione exerts anticancer effects on glioma cells through interaction with the mitochondrial electron transport chain. Neurosci Lett 639:207-14. | Rat | Nervous system Other cell lines | Nervous system Other cell lines |
Asiri 2017 Thesis | 2017 | Asiri A (2017) Effects of asiatic acid on neurite outgrowth in Neuro-2a cells. Master's Thesis p42. | Mouse | Nervous system | Nervous system |
Vigueira 2017 Exp Physiol | 2017 | Vigueira PA, McCommis KS, Hodges WT, Schweitzer GG, Cole SL, Oonthonpan L, Taylor EB, McDonald WG, Kletzien RF, Colca JR, Finck BN (2017) The beneficial metabolic effects of insulin sensitizers are not attenuated by mitochondrial pyruvate carrier 2 hypomorphism. Exp Physiol 102:985-99. | Human | Kidney HEK | Kidney HEK |
Pecinova 2017 Oxid Med Cell Longev | 2017 | Pecinova A, Drahota Z, Kovalcikova J, Kovarova N, Pecina P, Alan L, Zima M, Houstek J, Mracek T (2017) Pleiotropic effects of biguanides on mitochondrial reactive oxygen species production. Oxid Med Cell Longev 7038603. | Rat | Fat | Fat |
Alves 2017 Free Radic Biol Med | 2017 | Alves de Souza CE, Alves de Souza HM, Stipp MC, Corso CR, Galindo CM, Cardoso CR, Dittrich RL, de Souza Ramos EA, Klassen G, Carlos RM, Correia Cadena SMS, Acco A (2017) Ruthenium complex exerts antineoplastic effects that are mediated by oxidative stress without inducing toxicity in Walker-256 tumor-bearing rats. Free Radic Biol Med 110:228-39. | Rat | ||
Luethi 2017 Toxicology | 2017 | Luethi D, Liechti ME, Krähenbühl S (2017) Mechanisms of hepatocellular toxicity associated with new psychoactive synthetic cathinones. Toxicology 387:57-66. | Human | Liver | Liver |
Sharaf 2017 Biochim Biophys Acta | 2017 | Sharaf MS, Stevens D, Kamunde C (2017) Mitochondrial transition ROS spike (mTRS) results from coordinated activities of complex I and nicotinamide nucleotide transhydrogenase. Biochim Biophys Acta 1858:955-65. | Mouse Fishes | Heart Liver | Heart Liver |
Sharaf 2017 Aquat Toxicol | 2017 | Sharaf MS, Stevens D, Kamunde C (2017) Zinc and calcium alter the relationship between mitochondrial respiration, ROS and membrane potential in rainbow trout (Oncorhynchus mykiss) liver mitochondria. Aquat Toxicol 189:170-83. | Fishes | Liver | Liver |
Irgebay 2017 Breast | 2017 | Irgebay Z, Yeszhan B, Sen B, Tuleukhanov S, Brooks AD, Sensenig R, Orynbayeva Z (2017) Danazol alters mitochondria metabolism of fibrocystic breast Mcf10A cells. Breast 35:55-62. | Human | Genital | Genital |
Braz-Mota 2017 Thesis | 2017 | Braz Mota S (2017) Estudo comparativo da toxicidade e dos mecanismos de ação tóxica de nanopartículas de cobre e cobre em duas espécies de peixes da Amazônia: Apistogramma agassizii e Paracheirodon axelrodi. Dissertation p.78. | Fishes | Lung;gill | Lung;gill |
Canevarolo 2017 Thesis | 2017 | Canevarolo RR (2017) Resistência ao metotrexato está diretamente associada à concentração de glutationa em linhagens de leucemia linfoide aguda. Dissertation p159. | Human | Macrophage-derived | Macrophage-derived |
Thomas 2017 Thesis | 2017 | Thomas NO (2017) Age-related decrease in resilience against acute redox cycling agents: critical role of declining GSH-dependent detoxification capacity. Dissertation p141. | Rat | Liver | Liver |
Jespersen 2017 J Physiol | 2017 | Jespersen NR, Yokota T, Støttrup NB, Bergdahl A, Paelestik KB, Povlsen JA, Dela F, Bøtker HE (2017) Pre-ischaemic mitochondrial substrate constraint by inhibition of malate-aspartate shuttle preserves mitochondrial function after ischaemia-reperfusion. J Physiol 595:3765-80. | Rat | Heart | Heart |
Ruiz 2017 LWT- Food Science Technology | 2017 | Ruiz VE, Cerioni L, Zampini IC, Cuello S, Isla MI, Hilal M, Rapisarda VA (2017) UV-B radiation on lemons enhances antifungal activity of flavedo extracts against Penicillium digitatum. LWT- Food Science Technology 85:96-103. | Fungi | ||
Sobotka 2017 Thesis | 2017 | Sobotka O (2017) Pharmacological and metabolic influence on liver mitochondrial functions. PhD Thesis p127. | Mouse Rat | Liver | Liver |
Zhou 2017 Int J Biochem Mol Biol | 2017 | Zhou Q, Zhang H, Wu Q, Shi J, Zhou S (2017) Pharmacological manipulations of autophagy modulate paraquat-induced cytotoxicity in PC12 cells. Int J Biochem Mol Biol 8:13-22. | Rat | Kidney | Kidney |
Ortega-Dominguez 2017 Food Chem Toxicol | 2017 | Ortega-Domínguez B, Aparicio-Trejo OE, García-Arroyo FE, León-Contreras JC, Tapia E, Molina-Jijón E, Hernández-Pando R, Sánchez-Lozada LG, Barrera-Oviedo D, Pedraza-Chaverri J (2017) Curcumin prevents cisplatin-induced renal alterations in mitochondrial bioenergetics and dynamic. Food Chem Toxicol 107:373-85. | |||
Crouch 2017 PLOS ONE | 2017 | Crouch ML, Knowels G, Stuppard R, Ericson NG, Bielas JH, Marcinek DJ, Syrjala KL (2017) Cyclophosphamide leads to persistent deficits in physical performance and in vivo mitochondria function in a mouse model of chemotherapy late effects. PLOS ONE 12:e0181086. | Mouse | Skeletal muscle | Skeletal muscle |
Duicu 2017 Can J Physiol Pharmacol | 2017 | Duicu OM, Privistirescu A, Wolf A, Petruş A, Dănilă MD, Raţiu CD, Muntean DM, Sturza A (2017) Methylene blue improves mitochondrial respiration and decreases oxidative stress in a substrate-dependent manner in diabetic rat hearts. Can J Physiol Pharmacol 95:1376-82. | Rat | Heart | Heart |
Cunha 2017 Int J Biol Macromol | 2017 | Cunha de Padua MM, Suter Correia Cadena SM, de Oliveira Petkowicz CL, Martinez GR, Rodrigues Noleto G (2017) Galactomannan from Schizolobium amazonicum seed and its sulfated derivatives impair metabolism in HepG2 cells. Int J Biol Macromol 101:64-473. | Human | Liver | Liver |
Davis 2017 Tissue Eng Part C Methods | 2017 | Davis BN, Santoso JW, Walker MJ, Cheng CS, Koves TR, Kraus WE, Truskey GA (2017) Human, tissue-engineered, skeletal muscle myobundles to measure oxygen uptake and assess mitochondrial toxicity. Tissue Eng Part C Methods 23:189-99. | Human | Skeletal muscle | Skeletal muscle |
Wrobeln 2017 Eur J Pharm Biopharm | 2017 | Wrobeln A, Laudien J, Groß-Heitfeld C, Linders J, Mayer C, Wilde B, Knoll T, Naglav D, Kirsch M, Ferenz KB (2017) Albumin-derived perfluorocarbon-based artificial oxygen carriers: A physico-chemical characterization and first in vivo evaluation of biocompatibility. Eur J Pharm Biopharm pii: S0939-6411(16)30517-3. | |||
Jang 2017 Clin Toxicol (Phila) | 2017 | Jang DH, Kelly M, Hardy K, Lambert DS, Shofer FS, Eckmann DM (2017) A preliminary study in the alterations of mitochondrial respiration in patients with carbon monoxide poisoning measured in blood cells. Clin Toxicol (Phila) 55:579-84. | Blood cells | Blood cells | |
Honrath 2017 Cell Death Differ | 2017 | Honrath B, Matschke L, Meyer T, Magerhans L, Perocchi F, Ganjam GK, Zischka H, Krasel C, Gerding A, Bakker BM, Bünemann M, Strack S, Decher N, Culmsee C, Dolga AM (2017) SK2 channels regulate mitochondrial respiration and mitochondrial Ca2+ uptake. Cell Death Differ 24:761-73. | Mouse | Nervous system Other cell lines | Nervous system Other cell lines |
Ravasz 2017 Neurochem Int | 2017 | Ravasz D, Kacso G, Fodor V, Horvath K, Adam-Vizi V, Chinopoulos C (2017) Catabolism of GABA, succinic semialdehyde or gamma-hydroxybutyrate through the GABA shunt impair mitochondrial substrate-level phosphorylation. Neurochem Int 109:41-53. | Mouse | Nervous system Liver | Nervous system Liver |
Komlodi 2017 Neuropharmacology | 2017 | Komlódi T, Tretter L (2017) Methylene blue stimulates substrate-level phosphorylation catalysed by succinyl-CoA ligase in the citric acid cycle. Neuropharmacology 123:287-98. | Guinea pig | Nervous system | Nervous system |
Fink 2017 Pharmacol Res Perspect | 2017 | Fink BD, Guo DF, Kulkarni CA, Rahmouni K, Kerns RJ, Sivitz WI (2017) Metabolic effects of a mitochondrial-targeted coenzyme Q analog in high fat fed obese mice. Pharmacol Res Perspect 5:e00301. | Mouse | Liver | Liver |
Lopez-Manzano 2017 Chem Res Toxicol | 2017 | Lopez-Manzano E, Cronican AA, Frawley KL, Peterson J, Pearce LL (2017) Cyanide scavenging by a cobalt Schiff-base macrocycle: a cost-effective alternative to corrinoids. Chem Res Toxicol 29:1011-9. | |||
Yu 2017 Free Radic Biol Med | 2017 | Yu Y, Wang L, Delguste F, Durand A, Guilbaud A, Rousselin C, Schmidt AM, Tessier F, Boulanger E, Neviere R (2017) Advanced glycation end products receptor RAGE controls myocardial dysfunction and oxidative stress in high-fat fed mice by sustaining mitochondrial dynamics and autophagy-lysosome pathway. Free Radic Biol Med 112:397-410. | Mouse | Heart | Heart |
Seo 2017 Elife | 2017 | Seo AY, Lau PW, Feliciano D, Sengupta P, Gros MAL, Cinquin B, Larabell CA, Lippincott-Schwartz J (2017) AMPK and vacuole-associated Atg14p orchestrate μ-lipophagy for energy production and long-term survival under glucose starvation. Elife 6. pii: e21690. | Saccharomyces cerevisiae | ||
Uppala 2017 Biochem Biophys Res Commun | 2017 | Uppala R, Dudiak B, Beck ME, Bharathi SS, Zhang Y, Stolz DB, Goetzman ES (2017) Aspirin increases mitochondrial fatty acid oxidation. Biochem Biophys Res Commun 482:346-51. | Human Mouse | HEK Fibroblast | HEK Fibroblast |
Layne 2017 Contemp Clin Trials | 2017 | Layne AS, Krehbiel LM, Mankowski RT, Anton SD, Leeuwenburgh C, Pahor M, Sandesara B, Wu SS, Buford TW (2017) Resveratrol and exercise to treat functional limitations in late life: Design of a randomized controlled trial. Contemp Clin Trials 6:58–63. | Human | Skeletal muscle | Skeletal muscle |
Wolff 2017 Thesis | 2017 | Wolff C (2017) Impact of lipid metabolism on skeletal muscle mitochondrial function in type 2 diabetes mellitus patients. Dissertation p68. | Horse Human | Skeletal muscle | Skeletal muscle |
Napa 2017 Int J Dent | 2017 | Napa K, Baeder AC, Witt JE, Rayburn ST, Miller MG, Dallon BW, Gibbs JL, Wilcox SH, Winden DR, Smith JH, Reynolds PR, Bikman BT (2017) LPS from P. gingivalis negatively alters gingival cell mitochondrial bioenergetics. Int J Dent 2017:2697210. | Human | Endothelial;epithelial;mesothelial cell | Endothelial;epithelial;mesothelial cell |
Paech 2017 Arch Toxicol | 2017 | Paech F, Messner S, Spickermann J, Wind M, Schmitt-Hoffmann AH, Witschi AT, Howell BA, Church RJ, Woodhead J, Engelhardt M, Krähenbühl S, Maurer M (2017) Mechanisms of hepatotoxicity associated with the monocyclic β-lactam antibiotic BAL30072. Arch Toxicol 91:3647-62. | Human | Liver Other cell lines | Liver Other cell lines |
Saintas 2017 PLOS ONE | 2017 | Saintas E, Abrahams L, Ahmad GT, Ajakaiye AM, AlHumaidi AS, Ashmore-Harris C, Clark I, Dura UK, Fixmer CN, Ike-Morris C, Mato Prado M, Mccullough D, Mishra S, Schöler KM, Timur H, Williamson MD, Alatsatianos M, Bahsoun B, Blackburn E, Hogwood CE, Lithgow PE, Rowe M, Yiangou L, Rothweiler F, Cinatl J Jr, Zehner R, Baines AJ, Garrett MD, Gourlay CW, Griffin DK, Gullick WJ, Hargreaves E, Howard MJ, Lloyd DR, Rossman JS, Smales CM, Tsaousis AD, von der Haar T, Wass MN, Michaelis M (2017) Acquired resistance to oxaliplatin is not directly associated with increased resistance to DNA damage in SK-N-ASrOXALI4000, a newly established oxaliplatin-resistant sub-line of the neuroblastoma cell line SK-N-AS. PLOS ONE 12:e0172140. | Human | Nervous system Other cell lines | Nervous system Other cell lines |
Busanello 2017 Front Pharmacol | 2017 | Busanello ENB, Marques AC, Lander N, de Oliveira DN, Catharino RR, Oliveira HCF, Vercesi AE (2017) Pravastatin chronic treatment sensitizes hypercholesterolemic mice muscle to mitochondrial permeability transition: protection by creatine or coenzyme Q10. Front Pharmacol 8:185. | Mouse | Skeletal muscle | Skeletal muscle |
De Moura 2017 Neurotox Res | 2017 | de Moura Alvorcem L, da Rosa MS, Glänzel NM, Parmeggiani B, Grings M, Schmitz F, Wyse ATS, Wajner M, Leipnitz G (2017) Disruption of energy transfer and redox status by sulfite in hippocampus, striatum, and cerebellum of developing rats. Neurotox Res 32:264-75. | Rat | Nervous system | Nervous system |
Tueller 2017 Biochem Biophys Res Commun | 2017 | Tueller DJ, Harley JS, Hancock CR (2017) Effects of curcumin and ursolic acid on the mitochondrial coupling efficiency and hydrogen peroxide emission of intact skeletal myoblasts. Biochem Biophys Res Commun 492:368-72. | Skeletal muscle | Skeletal muscle | |
Varga 2017 Inflammopharmacology | 2017 | Varga G, Ugocsai M, Hartmann P, Lajkó N, Molnár R, Szűcs S, Jász DK, Érces D, Ghyczy M, Tóth G, Boros M (2017) Acetylsalicylic acid-tris-hydroxymethyl-aminomethane reduces colon mucosal damage without causing gastric side effects in a rat model of colitis. Inflammopharmacology 26:261-71. | Rat | Liver | Liver |
Da Silva 2017 Life Sci | 2017 | da Silva MH, Peçanha FLM, de Oliveira AM, da-Silva WS (2017) 4-Phenyl butyric acid increases particulate hexokinase activity and protects against ROS injury in L6 myotubes. Life Sci 179:98-102. | Rat | Skeletal muscle Other cell lines | Skeletal muscle Other cell lines |
Rademann 2017 Oxid Med Cell Longev | 2017 | Rademann P, Weidinger A, Drechsler S, Meszaros A, Zipperle J, Jafarmadar M, Dumitrescu S, Hacobian A, Ungelenk L, Röstel F, Kaszaki J, Szabo A, Skulachev VP, Bauer M, Bahrami S, Weis S, Kozlov AV, Osuchowski MF (2017) Mitochondria-targeted antioxidants SKQ1 and MitoTEMPO failed to exert a long-term beneficial effect in murine polymicrobial sepsis. Oxid Med Cell Longev 6412682. | Mouse Rat | Liver | Liver |
Kline 2017 Am Heart J | 2017 | Kline JA, Hall C, Jones AE, Pusckarich MA, Mastouri R, Lahm T (2017) Randomized trial of inhaled nitric oxide to treat acute pulmonary embolism: the iNOPE trial. Am Heart J 186:100–10. | Human | Blood cells Platelet | Blood cells Platelet |
De Carvalho 2017 Toxicol Research | 2017 | de Carvalho NR, Rodrigues NR, Macedo GE, Boligon AA, de Campos MM, Posser T, Cunha FAB, Coutinho HD, Klamt F, Bristot IJ, Merritt TJS, Franco JL (2017) Eugenia uniflora leaves essential oil promotes mitochondrial dysfunction in Drosophila melanogaster through the inhibition of oxidative phosphorylation. Toxicol Research 6:526-34 . | Drosophila | ||
Teplova 2017 Toxicol Lett | 2017 | Teplova VV, Belosludtsev KN, Kruglov AG (2017) Mechanism of triclosan toxicity: Mitochondrial dysfunction including complex II inhibition, superoxide release and uncoupling of oxidative phosphorylation. Toxicol Lett 275:108-17. | Rat | Liver | Liver |
Gruenig 2017 Toxicol In Vitro | 2017 | Grünig D, Felser A, Bouitbir J, Krähenbühl S (2017) The catechol-O-methyltransferase inhibitors tolcapone and entacapone uncouple and inhibit the mitochondrial respiratory chain in HepaRG cells. Toxicol In Vitro 42:337-47. | Human Mouse | Liver Other cell lines | Liver Other cell lines |
Greenall 2017 Oncogenesis | 2017 | Greenall SA, Lim YC, Mitchell CB, Ensbey KS, Stringer BW, Wilding AL, O'Neill GM, McDonald KL, Gough DJ, Day BW, Johns TG (2017) Cyclin-dependent kinase 7 is a therapeutic target in high-grade glioma. Oncogenesis 6:e336. | Human | Nervous system | Nervous system |
Rodolphi 2017 Thesis | 2017 | Rodolphi MS (2017) Efeitos da nandrolona e da ceftriaxona na homeostasia glutamatérgica: uma busca por mecanismos interativos entre astrócitos e neurônios envolvidos no comportamento agressivo. Dissertation p58. | Mouse | Nervous system | Nervous system |
Rekuviene 2017 Neurosci Lett | 2017 | Rekuviene E, Ivanoviene L, Borutaite V, Morkuniene R (2017) Rotenone decreases ischemia-induced injury by inhibiting mitochondrial permeability transition in mature brains. Neurosci Lett 653:45-50. | Rat | Nervous system | Nervous system |
Westphal 2017 US Patent | 2017 | Westphal S, Fromme T, Klingenspor M (2017) Fgf-8 for use in treating diseases or disorders of energy homeostasis. US Patent US20170258874 A1. | Mouse | ||
Min 2017 Skelet Muscle | 2017 | Min K, Lawan A, Bennett AM (2017) Loss of MKP-5 promotes myofiber survival by activating STAT3/Bcl-2 signaling during regenerative myogenesis. Skelet Muscle 7:21. | Mouse | Skeletal muscle | Skeletal muscle |
Cockova 2017 Thesis | 2017 | Čočková Z (2017) Modulation of RNA demethylase FTO function in SH-SY5Y cells: the effect on insulin signaling and mitochondrial respiration. Diploma Thesis p70. | Human | Nervous system | Nervous system |
Lores-Arnaiz 2017 J Neurochem | 2017 | Lores-Arnaiz S, Karadayian AG, Gutnisky A, Rodríguez de Lores Arnaiz G (2017) The low affinity neurotensin receptor antagonist levocabastine impairs brain nitric oxide synthesis and mitochondrial function by independent mechanisms. J Neurochem 143:684-96. | Rat | Nervous system | Nervous system |
Geoghegan 2017 Oncol Lett | 2017 | Geoghegan F, Chadderton N, Farrar GJ, Zisterer DM1, Porter RK (2017) Direct effects of phenformin on metabolism/bioenergetics and viability of SH-SY5Y neuroblastoma cells. Oncol Lett 14:6298-306. | Human | Nervous system | Nervous system |
Pino 2017 Int J Obes (Lond) | 2017 | Pino MF, Divoux A, Simmonds AV, Smith SR, Sparks LM (2017) Investigating the effects of Orexin-A on thermogenesis in human deep neck brown adipose tissue. Int J Obes (Lond) 41:1646-53. | Human | Fat | Fat |
Mitroshina 2017 Mod Technol Med | 2017 | Mitroshina ЕV, Abogessimengane BZ, Urazov МD, Hamraoui I, Mishchenko ТА, Astrakhanova ТА, Shchelchkova NА, Lapshin RD, Shishkina ТV, Belousova II, Mukhina IV, Vedunova МV (2017) Adaptive role of glial cell line-derived neurotrophic factor in cerebral ischemia. Mod Technol Med 9:68-76. | Mouse | Nervous system | Nervous system |
Cecatto 2017 Neurochem Int | 2017 | Cecatto C, Amaral AU, da Silva JC, Wajner A, Godoy KD, Ribeiro RT, Gonçalves AM, Vargas CR, Wajner M (2017) Mevalonolactone disrupts mitochondrial functions and induces permeability transition pore opening in rat brain mitochondria: Implications for the pathogenesis of mevalonic aciduria. Neurochem Int 108:133-45. | Rat | Nervous system Liver | Nervous system Liver |
Sivertsson 2017 Am J Physiol Renal Physiol | 2017 | Sivertsson E, Friederich-Persson M, Öberg CM, Fasching A, Hansell P, Rippe B, Palm F (2017) Inhibition of mammalian target of rapamycin decreases intrarenal oxygen availability and alters glomerular permeability. Am J Physiol Renal Physiol 314:F864-F872. | Rat | Kidney | Kidney |
Radenkovic 2017 Biochem Pharmacol | 2017 | Radenkovic F, Holland OJ, Vanderlelie JJ, Perkins AV (2017) Selective inhibition of endogenous antioxidants with Auranofin causes mitochondrial oxidative stress which can be countered by selenium supplementation. Biochem Pharmacol 146:42-52. | Human | Other cell lines | Other cell lines |
Ren 2017 Front Pharmacol | 2017 | Ren YJ, Wang XH, Ji C, Guan YD, Lu XJ, Liu XR, Zhang HH, Guo LC, Xu QH, Zhu WD, Ming ZJ, Yang JM, Cheng Y, Zhang Y (2017) Silencing of NAC1 expression induces cancer cells oxidative stress in hypoxia and potentiates the therapeutic activity of elesclomol. Front Pharmacol 8:804. | Human | HeLa Other cell lines | HeLa Other cell lines |
Valis 2017 Oncotarget | 2017 | Vališ K, Grobárová V, Hernychová L, Bugáňová M4, Kavan D, Kalous M, Černý J, Stodůlková E, Kuzma M, Flieger M, Černý J, Novák P (2017) Reprogramming of leukemic cell metabolism through the naphthoquinonic compound Quambalarine B. Oncotarget 8:103137-53. | Rat | Liver | Liver |
Zhang 2017 J Am Heart Assoc | 2017 | Zhang X, Zhang Z, Zhao Y, Jiang N, Qiu J, Yang Y, Li J, Liang X, Wang X, Tse G, Li G, Liu T (2017) Alogliptin, a dipeptidyl peptidase-4 inhibitor, alleviates atrial remodeling and improves mitochondrial function and biogenesis in diabetic rabbits. J Am Heart Assoc 6:e005945. | Rabbit | Heart | Heart |
Li 2017 Oxid Med Cell Longev | 2017 | Li CJ, Chen PK, Sun LY, Pang CY (2017) Enhancement of mitochondrial transfer by antioxidants in human mesenchymal stem cells. Oxid Med Cell Longev 2017:8510805. | Human | Fat | Fat |
Krishnathas 2017 Med Chem Comm | 2017 | Krishnathas R, Bonke E, Dröse S, Zickermann V, Nasiri HR (2017) Identification of 4-N-[2-(4-phenoxyphenyl)ethyl]quinazoline-4,6-diamine as a novel, highly potent and specific inhibitor of mitochondrial complex I. Med Chem Comm 8:657-61. | Rat | Heart | Heart |
Cunha-de 2017 Thesis | 2017 | Cunha-de Padua MM (2017) Mecanismos citotóxicos da galactomanana de sementes de Schizolobium amazonicum e seus complexos com oxovanádio em células de hepatocarcinoma humano (HepG2) e efeito do silenciamento da enzima glucose-6-fosfato isomerase (GPI) na sobrevivência de células de adenocarcinoma de cólon humano (LS174T). Doctoral Thesis p160. | Human | Liver Other cell lines | Liver Other cell lines |
Selwood 2017 US Patent | 2017 | Selwood DL, Baker D, Szabadkai G, Duchen MR, Hill JM, Warne JND (2017) Quinolium conjugates of cyclosporin. US Patent US20170349632 A1. | Mouse | Liver | Liver |
Balcaitis 2017 Thesis | 2017 | Balcaitis D (2017) The investigation of derivates of the 1,4-naphthoquinone effects to mitochondrial oxygen consumption in glioblastoma cells. Diploma Thesis p43. | Rat | Nervous system Other cell lines | Nervous system Other cell lines |
Nemeth 2017 Thesis | 2017 | Németh B (2017) The effect of itaconic acid on mitochondrial substrate-level phosphorylation. PhD Thesis p84. | Mouse | Liver | Liver |
Martins 2017 Thesis | 2017 | Martins WC (2017) Estudo do efeito protetor da atorvastatina e dos eventos iniciais da neurotoxicidade induzida pelo peptídeo β-amilóide (Aβ1-40) em camundongos. Doctoral Thesis p85. | Mouse | Nervous system | Nervous system |
Wrobeln 2017 Artif Cells Nanomed Biotechnol | 2017 | Wrobeln A, Schlüter KD, Linders J, Zähres M, Mayer C, Kirsch M, Ferenz KB (2017) Functionality of albumin-derived perfluorocarbon-based artificial oxygen carriers in the Langendorff-heart. Artif Cells Nanomed Biotechnol 45:723-30. | |||
Xhani 2017 Thesis | 2017 | Xhani M (2017) Cellular redox homeostasis and environmental toxicity. Dissertation p110. | Human | Liver Other cell lines | Liver Other cell lines |
Elmer 2017 US Patent | 2017 | Elmer E, Hansson MJ, Ehinger JK, Piel S, Moss S (2017) Succinate prodrugs for use in the treatment of lactic acidosis or drug-induced side-effects due to complex I-related impairment of mitochondrial oxidative phosphorylation. US Patent US20170100359 A1. | Human | Heart Blood cells Fibroblast Macrophage-derived Platelet | Heart Blood cells Fibroblast Macrophage-derived Platelet |
Frawley 2017 Chem Res Toxicol | 2017 | Frawley KL, Cronican AA, Pearce LL, Peterson J (2017) Sulfide toxicity and its modulation by nitric oxide in bovine pulmonary artery endothelial cells. Chem Res Toxicol 30:2100-9. | Bovines | Endothelial;epithelial;mesothelial cell | Endothelial;epithelial;mesothelial cell |
Cardinale 2017 Front Physiol | 2017 | Cardinale DA, Lilja M, Mandić M, Gustafsson T, Larsen FJ, Lundberg TR (2017) Resistance training with co-ingestion of anti-inflammatory drugs attenuates mitochondrial function. Front Physiol 8:1074. | Human | Skeletal muscle | Skeletal muscle |
Qi 2017 Ann Allergy Asthma Immunol | 2017 | Qi S, Cindy Barnig C, Charles AL, Poirot A, Meyer A, Clere-Jehl R, de Blay F, Geny B (2017) Nasal allergen challenge in allergic rhinitis induces mitochondrial dysfunction of peripheral blood mononuclear cells. Ann Allergy Asthma Immunol 118:367-9. | Human | Blood cells Lymphocyte | Blood cells Lymphocyte |
Rowley 2017 J Nutr Biochem | 2017 | Rowley TJ, Bitner BF, Ray JD, Lathen DR, Smithson AT, Dallon BW, Plowman CJ, Bikman BT, Hansen JM, Dorenkott MR, Goodrich KM, Ye L, O'Keefe SF, Neilson AP, Tessem JS (2017) Monomeric cocoa catechins enhance β-cell function by increasing mitochondrial respiration. J Nutr Biochem 49:30-41. | Rat | Islet cell;pancreas;thymus | Islet cell;pancreas;thymus |
Yang 2017 Cell Death Dis | 2017 | Yang N, Weinfeld M, Lemieux H, Montpetit B, Goping IS (2017) Photo-activation of the delocalized lipophilic cation D112 potentiates cancer selective ROS production and apoptosis. Cell Death Dis 8:e2587. | Saccharomyces cerevisiae Human | Lymphocyte | Lymphocyte |
Goncalves 2017 J Cell Commun Signal | 2017 | Gonçalves R, Zamoner A, Zanatta L, Zanatta AP, Remor AP, da Luz Scheffer D, Latini A, Silva FR (2017) 1,25(OH)2 vitamin D3 signalling on immature rat Sertoli cells: gamma-glutamyl transpeptidase and glucose metabolism. J Cell Commun Signal 11:233-43. | Rat | Genital | Genital |
Wetzel 2017 Thesis | 2017 | Wetzel MD (2017) Mechanism of metformin action in dermal fibroblasts. PhD Thesis 125. | Human | Fibroblast | Fibroblast |
Rowley 2017 Thesis | 2017 | Rowley TJ (2017) The effect of cocoa flavanols on β-cell mass and function. Master's Thesis p131. | Rat | Islet cell;pancreas;thymus | Islet cell;pancreas;thymus |
Yeh 2017 Thesis | 2017 | Yeh A (2017) Modulation of mitochondrial function as an indicator for sublethal effects of contaminants of emerging concern. Dissertation p117. | Human Fishes | Liver | Liver |
Da Silva 2017 Neurotox Res | 2017 | Da Silva JC, Amaral AU, Cecatto C, Wajner A, Dos Santos Godoy K, Ribeiro RT, de Mello Gonçalves A, Zanatta Â, da Rosa MS, Loureiro SO, Vargas CR, Leipnitz G, de Souza DOG, Wajner M (2017) α-Ketoadipic acid and α-aminoadipic acid cause disturbance of glutamatergic neurotransmission and induction of oxidative stress in vitro in brain of adolescent rats. Neurotox Res 32:276-90. | Rat | Nervous system | Nervous system |
Magnifico 2017 Oxid Med Cell Longev | 2017 | Magnifico MC, Oberkersch RE, Mollo A, Giambelli L, Grooten Y, Sarti P, Calabrese GC, Arese M (2017) VLDL induced modulation of nitric oxide signalling and cell redox homeostasis in HUVEC. Oxid Med Cell Longev 2017:2697364. | Human | Endothelial;epithelial;mesothelial cell | Endothelial;epithelial;mesothelial cell |