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{{#ask: [[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[MiP area::Pharmacology;toxicology]]
 |?Was published in year=Year
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{
    "query_string": "[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[MiP area::Pharmacology;toxicology]]",
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	Year	Reference	Organism	Tissue;cell	Tissue and cell
Ravasz 2017 Neurochem Int	2017	Ravasz D, Kacso G, Fodor V, Horvath K, Adam-Vizi V, Chinopoulos C (2017) Catabolism of GABA, succinic semialdehyde or gamma-hydroxybutyrate through the GABA shunt impair mitochondrial substrate-level phosphorylation. Neurochem Int 109:41-53.	Mouse	Nervous system Liver	Nervous system Liver
Dixit 2017 Free Radic Biol Med	2017	Dixit S, Fessel JP, Harrison FE (2017) Mitochondrial dysfunction in the APP/PSEN1 mouse model of Alzheimer's disease and a novel protective role for ascorbate. Free Radic Biol Med 112:515-23.	Mouse	Heart	Heart
Rademann 2017 Oxid Med Cell Longev	2017	Rademann P, Weidinger A, Drechsler S, Meszaros A, Zipperle J, Jafarmadar M, Dumitrescu S, Hacobian A, Ungelenk L, Röstel F, Kaszaki J, Szabo A, Skulachev VP, Bauer M, Bahrami S, Weis S, Kozlov AV, Osuchowski MF (2017) Mitochondria-targeted antioxidants SKQ1 and MitoTEMPO failed to exert a long-term beneficial effect in murine polymicrobial sepsis. Oxid Med Cell Longev 6412682.	Mouse Rat	Liver	Liver
Sivertsson 2017 Am J Physiol Renal Physiol	2017	Sivertsson E, Friederich-Persson M, Öberg CM, Fasching A, Hansell P, Rippe B, Palm F (2017) Inhibition of mammalian target of rapamycin decreases intrarenal oxygen availability and alters glomerular permeability. Am J Physiol Renal Physiol 314:F864-F872.	Rat	Kidney	Kidney
Alves 2017 Free Radic Biol Med	2017	Alves de Souza CE, Alves de Souza HM, Stipp MC, Corso CR, Galindo CM, Cardoso CR, Dittrich RL, de Souza Ramos EA, Klassen G, Carlos RM, Correia Cadena SMS, Acco A (2017) Ruthenium complex exerts antineoplastic effects that are mediated by oxidative stress without inducing toxicity in Walker-256 tumor-bearing rats. Free Radic Biol Med 110:228-39.	Rat
Ruiz 2017 LWT- Food Science Technology	2017	Ruiz VE, Cerioni L, Zampini IC, Cuello S, Isla MI, Hilal M, Rapisarda VA (2017) UV-B radiation on lemons enhances antifungal activity of flavedo extracts against Penicillium digitatum. LWT- Food Science Technology 85:96-103.	Fungi
Saintas 2017 PLOS ONE	2017	Saintas E, Abrahams L, Ahmad GT, Ajakaiye AM, AlHumaidi AS, Ashmore-Harris C, Clark I, Dura UK, Fixmer CN, Ike-Morris C, Mato Prado M, Mccullough D, Mishra S, Schöler KM, Timur H, Williamson MD, Alatsatianos M, Bahsoun B, Blackburn E, Hogwood CE, Lithgow PE, Rowe M, Yiangou L, Rothweiler F, Cinatl J Jr, Zehner R, Baines AJ, Garrett MD, Gourlay CW, Griffin DK, Gullick WJ, Hargreaves E, Howard MJ, Lloyd DR, Rossman JS, Smales CM, Tsaousis AD, von der Haar T, Wass MN, Michaelis M (2017) Acquired resistance to oxaliplatin is not directly associated with increased resistance to DNA damage in SK-N-ASrOXALI4000, a newly established oxaliplatin-resistant sub-line of the neuroblastoma cell line SK-N-AS. PLOS ONE 12:e0172140.	Human	Nervous system Other cell lines	Nervous system Other cell lines
Yeh 2017 Thesis	2017	Yeh A (2017) Modulation of mitochondrial function as an indicator for sublethal effects of contaminants of emerging concern. Dissertation p117.	Human Fishes	Liver	Liver
Cunha de Padua 2017 Carbohydr Polym	2017	Cunha de Padua MM, Suter Correia Cadena SM, de Oliveira Petkowicz CL, Martinez GR, Rodrigues Noleto G (2017) Toxicity of native and oxovanadium (IV/V) galactomannan complexes on HepG2 cells is related to impairment of mitochondrial functions. Carbohydr Polym 173:665-75.	Human	Liver	Liver
Bueno 2016 Thesis	2016	Bueno e Silva MM (2016) Alterações mitocondriais e reprogramação metabólica em células de glioblastoma após tratamento com temozolomida. Dissertation p71.	Human	Nervous system Other cell lines	Nervous system Other cell lines
Fonseca-Berzal 2016 Parasitology	2016	Fonseca-Berzal C, DA Silva CF, Menna-Barreto RF, Batista MM, Escario JA, Arán VJ, Gómez-Barrio A, Soeiro Mde N (2016) Biological approaches to characterize the mode of action of two 5-nitroindazolinone prototypes on Trypanosoma cruzi bloodstream trypomastigotes. Parasitology 143:1469-78.	Protists
Morad 2016 J Lipid Res	2016	Morad SA, Ryan TE, Neufer PD, Zeczycki TN, Davis TS, MacDougall MR, Fox TE, Tan SF, Feith DJ, Loughran TP Jr, Kester M, Claxton DF, Barth BM, Deering TG, Cabot MC (2016) Ceramide-tamoxifen regimen targets bioenergetic elements in acute myelogenous leukemia. J Lipid Res 57:1231-42.	Human	Blood cells Other cell lines	Blood cells Other cell lines
Hawley 2016 Diabetes	2016	Hawley SA, Ford RJ, Smith BK, Gowans GJ, Mancini SJ, Pitt RD, Day EA, Salt IP, Steinberg GR, Hardie DG (2016) The Na+/glucose cotransporter inhibitor canagliflozin activates AMPK by inhibiting mitochondrial function and increasing cellular AMP levels. Diabetes 65:2784-94.	Human Mouse	Liver HEK	Liver HEK
Raesaenen 2016 Proc Natl Acad Sci U S A	2016	Räsänen M, Degerman J, Nissinen TA, Miinalainen I, Kerkelä R, Siltanen A, Backman JT, Mervaala E, Hulmi JJ, Kivelä R, Alitalo K (2016) VEGF-B gene therapy inhibits doxorubicin-induced cardiotoxicity by endothelial protection. Proc Natl Acad Sci U S A 113:13144-49.	Mouse	Heart	Heart
Mills 2016 Cell Metab	2016	Mills KF, Yoshida S, Stein LR, Uchida K, Yoshino J, Imai SI (2016) Long-term administration of nicotinamide mononucleotide mitigates age-associated physiological decline in mice. Cell Metab 24:1–12.	Mouse	Skeletal muscle	Skeletal muscle
Strifler 2016 PLOS ONE	2016	Strifler G, Tuboly E, Szél E, Kaszonyi E, Cao C, Kaszaki J, Mészáros A, Boros M, Hartmann P (2016) Inhaled methane limits the mitochondrial electron transport chain dysfunction during experimental liver ischemia-reperfusion injury. PLOS ONE 11:e0146363.	Rat	Liver	Liver
Berressem 2016 PLOS ONE	2016	Berressem D, Koch K, Franke N, Klein J, Eckert GP (2016) Intravenous treatment with a long-chain omega-3 lipid emulsion provides neuroprotection in a murine model of ischemic stroke - a pilot study. PLOS ONE 11:e0167329.	Mouse	Nervous system	Nervous system
Reich 2016 Thesis	2016	Reich V (2016) Pathophysiologie und Verfahrensentwicklung: Mechanismen der Metabolisierung von Schwefelwasserstoff im mitochondrialen Atmungskreislauf von Lungenalveolarmakrophagen. Dissertation p91.	Mouse	Macrophage-derived	Macrophage-derived
Chang 2016 Transl Res	2016	Chang JC, Wu SL, Liu KH, Chen YH, Chuang CS, Cheng FC, Su HL, Wei YH, Kuo SJ, Liu CS (2016) Allogeneic/xenogeneic transplantation of peptide-labeled mitochondria in Parkinson's disease: restoration of mitochondria functions and attenuation of 6-hydroxydopamine-induced neurotoxicity. Transl Res 170:40-56.	Rat	Nervous system Other cell lines	Nervous system Other cell lines
Most 2016 Am J Clin Nutr	2016	Most J, Timmers S, Warnke I, Jocken JW, van Boekschoten M, de Groot P, Bendik I, Schrauwen P, Goossens GH, Blaak EE (2016) Combined epigallocatechin-3-gallate and resveratrol supplementation for 12 wk increases mitochondrial capacity and fat oxidation, but not insulin sensitivity, in obese humans: a randomized controlled trial. Am J Clin Nutr 104:215-27.	Human	Skeletal muscle	Skeletal muscle
Timmers 2016 Diabetes Care	2016	Timmers S, de Ligt M, Phielix E, van de Weijer T, Hansen J, Moonen-Kornips E, Schaart G, Kunz I, Hesselink MK, Schrauwen-Hinderling VB, Schrauwen P (2016) Resveratrol as add-on therapy in subjects with well-controlled type 2 diabetes: a randomized controlled trial. Diabetes Care 39:2211-17.	Human	Skeletal muscle	Skeletal muscle
Bouitbir 2016 Antioxid Redox Signal	2016	Bouitbir J, Singh F, Charles AL, Schlagowski AI, Bonifacio A, Echaniz-Laguna A, Geny B, Krähenbühl S, Zoll J (2016) Statins trigger mitochondrial ROS-induced apoptosis in glycolytic skeletal muscle. Antioxid Redox Signal 24:84-98.	Rat	Skeletal muscle Other cell lines	Skeletal muscle Other cell lines
Nissinen 2016 Sci Rep	2016	Nissinen TA, Degerman J, Räsänen M, Poikonen AR, Koskinen S, Mervaala E, Pasternack A, Ritvos O, Kivelä R, Hulmi JJ (2016) Systemic blockade of ACVR2B ligands prevents chemotherapy-induced muscle wasting by restoring muscle protein synthesis without affecting oxidative capacity or atrogenes. Sci Rep 6:32695.	Mouse	Skeletal muscle	Skeletal muscle
Timpani 2016 Neurotherapeutics	2016	Timpani CA, Trewin AJ, Stojanovska V, Robinson A, Goodman CA, Nurgali K, Betik AC, Stepto N, Hayes A, McConell GK, Rybalka E (2016) Attempting to compensate for reduced neuronal nitric oxide synthase protein with nitrate supplementation cannot overcome metabolic dysfunction but rather has detrimental effects in Dystrophin-deficient mdx muscle. Neurotherapeutics 14:429-46.	Mouse	Skeletal muscle	Skeletal muscle
Cannon 2016 Lung	2016	Cannon DT, Liu J, Sakurai R, Rossiter HB, Rehan VK (2016) Impaired lung mitochondrial respiration following perinatal nicotine exposure in rats. Lung 194:325-8.	Rat	Lung;gill	Lung;gill
Heinonen 2016 Hum Exp Toxicol	2016	Heinonen JA, Schramko AA, Skrifvars MB, Litonius E, Backman JT, Mervaala E, Rosenberg PH (2016) The effects of intravenous lipid emulsion on hemodynamic recovery and myocardial cell mitochondrial function after bupivacaine toxicity in anesthetized pigs. Hum Exp Toxicol 36:365-75.	Pig	Heart	Heart
Dutra 2016 Acta Trop	2016	Dutra FL, Oliveira MM, Santos RS, Silva WS, Alviano DS, Vieira DP, Lopes AH (2016) Effects of linalool and eugenol on the survival of Leishmania (L.) infantum chagasi within macrophages. Acta Trop 164:69-76.	Protists
Davuluri 2016 J Physiol	2016	Davuluri G, Allawy A, Thapaliya S, Rennison JH, Singh D, Kumar A, Sandlers Y, Van Wagoner DR, Flask CA, Hoppel C, Kasumov T, Dasarathy S (2016) Hyperammonaemia-induced skeletal muscle mitochondrial dysfunction results in cataplerosis and oxidative stress. J Physiol 594:7341-60.	Mouse	Skeletal muscle Other cell lines	Skeletal muscle Other cell lines
Castellano-Gonzalez 2016 Oncotarget	2016	Castellano-González G, Pichaud N, Ballard JW, Bessede A, Marcal H, Guillemin GJ (2016) Epigallocatechin-3-gallate induces oxidative phosphorylation by activating cytochrome c oxidase in human cultured neurons and astrocytes. Oncotarget 7:7426-40	Human	Nervous system	Nervous system
Mesquita 2016 Thesis	2016	Mesquita Rodrigues C (2016) Efeito da depleção de ferro sobre Leishmania (Viannia) braziliensisuma análise ultraestrutural, proteômica e interação com matrizes de colágeno sintéticas. Doctoral Dissertation p210.	Protists
Wijermars 2016 Kidney Int	2016	Wijermars LG, Schaapherder AF, de Vries DK, Verschuren L, Wuest RC, Kostidis S, Mayboroda OA, Prins F, Ringers J, Bierau J, Bakker JA, Kooistra T, Lindeman JH (2016) Defective postreperfusion metabolic recovery directly associates with incident delayed graft function. Kidney Int 90:181-91.	Human	Kidney	Kidney
Ehinger 2016 Nat Commun	2016	Ehinger JK, Piel S, Ford R, Karlsson M, Sjövall F, Frostner EÅ, Morota S, Taylor RW, Turnbull DM, Cornell C, Moss SJ, Metzsch C, Hansson MJ, Fliri H, Elmér E (2016) Cell-permeable succinate prodrugs bypass mitochondrial Complex I deficiency. Nat Commun 7:12317. https://doi.org/10.1038/ncomms12317		Heart Blood cells Fibroblast	Heart Blood cells Fibroblast
Mezera 2016 Oxid Med Cell Longev	2016	Mezera V, Endlicher R, Kucera O, Sobotka O, Drahota Z, Cervinkova Z (2016) Effects of epigallocatechin gallate on tert-butyl hydroperoxide-induced mitochondrial dysfunction in rat liver mitochondria and hepatocytes. Oxid Med Cell Longev 7573131:8pp.	Rat	Liver	Liver
Soendergaard 2016 Eur J Sport Sci	2016	Søndergård SD, Dela F, Helge JW, Larsen S (2016) Actovegin, a non-prohibited drug increases oxidative capacity in human skeletal muscle. Eur J Sport Sci 16:801-7.	Human	Skeletal muscle	Skeletal muscle
Xiong 2016 Hypertension	2016	Xiong S, Wang P, Ma L, Gao P, Gong L, Li L, Li Q, Sun F, Zhou X, He H, Chen J, Yan Z, Liu D, Zhu Z (2016) Ameliorating endothelial mitochondrial dysfunction restores coronary function via transient receptor potential vanilloid 1-mediated protein kinase A/uncoupling protein 2 pathway. Hypertension 67:451-60.	Human	Endothelial;epithelial;mesothelial cell Other cell lines	Endothelial;epithelial;mesothelial cell Other cell lines
Thomas 2016 Neurodegeneration Therapeutics	2016	Thomas RR, Keeney PM, Berr SB, Khan SM, Portell FR, Shakenov MZ, Antkowiak PF, Kundu B, Tustison N, Brohawn DG, Bennett JP (2016) Recombinant human TFAM stimulates rat brain, rat cervical spinal cord and human neural stem cell mitochondrial bioenergetics. Neurodegeneration Therapeutics p41.	Rat	Nervous system	Nervous system
Pohland 2016 Neurochem Res	2016	Pohland M, Hagl S, Pellowska M, Wurglics M, Schubert-Zsilavecz M, Eckert GP (2016) MH84: a novel γ-secretase modulator/PPARγ agonist-improves mitochondrial dysfunction in a cellular model of Alzheimer's disease. Neurochem Res 41:231-42.	Human	Kidney HEK	Kidney HEK
Witt 2016 Metab Brain Dis	2016	Witt AM, Larsen FS, Bjerring PN (2016) Accumulation of lactate in the rat brain during hyperammonaemia is not associated with impaired mitochondrial respiratory capacity. Metab Brain Dis 32:461-70.	Rat	Nervous system	Nervous system
Wang 2016 Toxicol Sci	2016	Wang L, Espinoza HM, MacDonald JW, Bammler TK, Williams CR, Yeh A, Louie KW, Marcinek DJ, Gallagher EP (2016) Olfactory Transcriptional Analysis of Salmon Exposed to Mixtures of Chlorpyrifos and Malathion Reveal Novel Molecular Pathways of Neurobehavioral Injury. Toxicol Sci 149:145-57.	Fishes	Endothelial;epithelial;mesothelial cell	Endothelial;epithelial;mesothelial cell
Zhunussova 2016 PLOS ONE	2016	Zhunussova A, Vitol EA, Polyak B, Tuleukhanov S, Brooks AD, Sensenig R, Friedman G, Orynbayeva Z (2016) Mitochondria-mediated anticancer effects of non-thermal atmospheric plasma. PLOS ONE 11:e0156818.	Human	Genital Other cell lines	Genital Other cell lines
Singh 2016 Mol Neurobiol	2016	Singh N, Hroudová J, Fišar Z (2016) In vitro effects of cognitives and nootropics on mitochondrial respiration and monoamine oxidase activity. Mol Neurobiol 54:5894-904.	Pig	Nervous system	Nervous system
Smith 2016 Diabetes	2016	Smith BK, Ford RJ, Desjardins EM, Green AE, Hughes MC, Houde VP, Day EA, Marcinko K, Crane JD, Mottillo EP, Perry CG, Kemp BE, Tarnopolsky MA, Steinberg GR (2016) Salsalate (Salicylate) uncouples mitochondria, improves glucose homeostasis, and reduces liver lipids independent of AMPK β1. Diabetes 65:3352-61.	Mouse	Skeletal muscle Liver Fat	Skeletal muscle Liver Fat
Amaral 2016 J Neurochem	2016	Amaral AU, Cecatto C, Castilho RF, Wajner M (2016) 2-methylcitric acid impairs glutamate metabolism and induces permeability transition in brain mitochondria. J Neurochem 137:62-75.	Rat	Nervous system	Nervous system
Bonifacio 2016 Arch Toxicol	2016	Bonifacio A, Mullen PJ, Mityko IS, Navegantes LC, Bouitbir J, Krähenbühl S (2016) Simvastatin induces mitochondrial dysfunction and increased atrogin-1 expression in H9c2 cardiomyocytes and mice in vivo. Arch Toxicol 90:203-15. doi: 10.1007/s00204-014-1378-4	Rat	Heart	Heart
Du 2016 Aquat Toxicol	2016	Du X, Crawford DL, Nacci DE, Oleksiak MF (2016) Heritable oxidative phosphorylation differences in a pollutant resistant Fundulus heteroclitus population. Aquat Toxicol 177:44-50.	Fishes	Liver	Liver
Volt 2016 J Pineal Res	2016	Volt H, García JA, Doerrier C, Díaz-Casado ME, Guerra-Librero A, López LC, Escames G, Tresguerres JA, Acuña-Castroviejo D (2016) Same molecule but different expression: aging and sepsis trigger NLRP3 inflammasome activation, a target of melatonin. J Pineal Res 60:193-205.	Mouse	Heart	Heart
Vevera 2016 Physiol Res	2016	Vevera J, Fišar Z, Nekovářová T, Vrablík M, Zlatohlávek L, Hroudová J, Singh N, Raboch J, Valeš K (2016) Statin-induced changes in mitochondrial respiration in blood platelets in rats and human with dyslipidemia. Physiol Res 65:777-88.	Human Rat	Blood cells Platelet	Blood cells Platelet
Reis 2016 Aging (Albany NY)	2016	Reis FC, Branquinho JL, Brandão BB, Guerra BA, Silva ID, Frontini A, Thomou T, Sartini L, Cinti S, Kahn CR, Festuccia WT, Kowaltowski AJ, Mori MA (2016) Fat-specific Dicer deficiency accelerates aging and mitigates several effects of dietary restriction in mice. Aging (Albany NY) 8:1201-22.	Mouse	Fat	Fat
Shirey 2016 Biochemistry	2016	Shirey K, Stover KR, Cleary J, Hoang N, Hosler J (2016) Membrane-anchored cyclic peptides as effectors of mitochondrial oxidative phosphorylation. Biochemistry 55:2100-11.	Rat	Heart Liver	Heart Liver
Cecatto 2016 Thesis	2016	Cecatto C (2016) Efeitos de acidos graxos hidroxilados de cadeia longa acumulados nas deficiencias da 3-hidroxiacil CoA desidrogenase de cadeia longa e da proteina trifunctional mitocondrial sobre a homeostase energetica mitochondrial nos musculos cardiaco e esqueletico de ratos jovens. Dissertation p103.	Rat	Heart Skeletal muscle	Heart Skeletal muscle
Kucera 2016 Drug Chem Toxicol	2016	Kučera O, Endlicher R, Rychtrmoc D, Lotková H, Sobotka O, Červinková Z (2016) Acetaminophen toxicity in rat and mouse hepatocytes in vitro. Drug Chem Toxicol 40:448-56.	Mouse Rat	Liver	Liver
Cheng 2016 Nat Immunol	2016	Cheng SC, Scicluna BP, Arts RJ, Gresnigt MS, Lachmandas E, Giamarellos-Bourboulis EJ, Kox M, Manjeri GR, Wagenaars JA, Cremer OL, Leentjens J, van der Meer AJ, van de Veerdonk FL, Bonten MJ, Schultz MJ, Willems PH, Pickkers P, Joosten LA, van der Poll T, Netea MG (2016) Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis. Nat Immunol 17:406-13.	Human	Blood cells Lymphocyte	Blood cells Lymphocyte
Gilliam 2016 Am J Physiol Endocrinol Metab	2016	Gilliam LA, Lark DS, Reese LR, Torres MJ, Ryan TE, Lin CT, Cathey BL, Neufer PD (2016) Targeted overexpression of mitochondrial catalase protects against cancer chemotherapy-induced skeletal muscle dysfunction. Am J Physiol Endocrinol Metab 311:E293-301.	Mouse	Skeletal muscle	Skeletal muscle
Liu 2016 Apoptosis	2016	Liu X, Gao RW, Li M, Si CF, He YP, Wang M, Yang Y, Zheng QY, Wang CY (2016) The ROS derived mitochondrial respiration not from NADPH oxidase plays key role in Celastrol against angiotensin II-mediated HepG2 cell proliferation. Apoptosis 21:1315-26.	Human	Liver Other cell lines	Liver Other cell lines
Jang 2016 Clin Toxicol (Phila)	2016	Jang DH, Shofer FS, Weiss SL, Becker LB (2016) Impairment of mitochondrial respiration following ex vivo cyanide exposure in peripheral blood mononuclear cells. Clin Toxicol (Phila) 54:303-7.	Human	Blood cells Lymphocyte	Blood cells Lymphocyte
Van Hoose 2016 J Nutr Biochem	2016	Van Hoose PM, Kelm NQ, Piell KM, Cole MP (2016) Conjugated linoleic acid and nitrite attenuate mitochondrial dysfunction during myocardial ischemia. J Nutr Biochem 34:8-16.	Mouse	Heart	Heart
Sanchez-Calvo 2016 PLOS ONE	2016	Sánchez-Calvo B, Cassina A, Rios N, Peluffo G, Boggia J, Radi R, Rubbo H, Trostchansky A (2016) Nitro-arachidonic acid prevents Angiotensin II-induced mitochondrial dysfunction in a cell line of kidney proximal tubular cells. PLOS ONE 11:e0150459.	Human	Kidney Other cell lines	Kidney Other cell lines
Eisenberg 2016 Nat Med	2016	Eisenberg T, Abdellatif M, Schroeder S, Primessnig U, Stekovic S, Pendl T, Harger A, Schipke J, Zimmermann A, Schmidt A, Tong M, Ruckenstuhl C, Dammbrueck C, Gross AS, Herbst V, Magnes C, Trausinger G, Narath S, Meinitzer A, Hu Z, Kirsch A, Eller K, Carmona-Gutierrez D, Büttner S, Pietrocola F, Knittelfelder O, Schrepfer E, Rockenfeller P, Simonini C, Rahn A, Horsch M, Moreth K, Beckers J, Fuchs H, Gailus-Durner V, Neff F, Janik D, Rathkolb B, Rozman J, de Angelis MH, Moustafa T, Haemmerle G, Mayr M, Willeit P, von Frieling-Salewsky M, Pieske B, Scorrano L, Pieber T, Pechlaner R, Willeit J, Sigrist SJ, Linke WA, Mühlfeld C, Sadoshima J, Dengjel J, Kiechl S, Kroemer G, Sedej S, Madeo F (2016) Cardioprotection and lifespan extension by the natural polyamine spermidine. Nat Med 22:1428-38.	Mouse	Heart	Heart
Jang 2016 J Intensive Care Med	2016	Jang DH, Greenwood JC, Spyres MB, Eckmann D (2016) Measurement of mitochondrial respiration and motility in acute care: sepsis, trauma, and poisoning. J Intensive Care Med 32:86-94.	Human	Blood cells Lymphocyte	Blood cells Lymphocyte
Villani 2016 Mol Metab	2016	Villani LA, Smith BK, Marcinko K, Ford RJ, Broadfield LA, Green AE, Houde VP, Muti P, Tsakiridis T, Steinberg GR (2016) The diabetes medication Canagliflozin reduces cancer cell proliferation by inhibiting mitochondrial complex-I supported respiration. Mol Metab 5:1048-56.	Human	Genital	Genital
Baeder 2016 Int J Dent	2016	Baeder AC, Napa K, Richardson ST, Taylor OJ, Andersen SG, Wilcox SH, Winden DR, Reynolds PR, Bikman BT (2016) Oral gingival cell cigarette smoke exposure induces muscle cell metabolic disruption. Int J Dent 2016:2763160.	Mouse	Skeletal muscle	Skeletal muscle
Iglesias-Gonzalez 2016 Mol Neurobiol	2016	Iglesias-González J, Sánchez-Iglesias S, Beiras-Iglesias A, Méndez-Álvarez E, Soto-Otero R (2016) Effects of aluminium on rat brain mitochondria bioenergetics: an in vitro and in vivo study. Mol Neurobiol 54:563-70.	Rat	Nervous system	Nervous system
Brandt 2016 Chem Biol Interact	2016	Brandt AP, Gozzi GJ, Pires Ado R, Martinez GR, Dos Santos Canuto AV, Echevarria A, Di Pietro A, Cadena SM (2016) Impairment of oxidative phosphorylation increases the toxicity of SYD-1 on hepatocarcinoma cells (HepG2). Chem Biol Interact 256:154-60.	Human	Liver Other cell lines	Liver Other cell lines
Moriyama 2016 J Surg Res	2016	Moriyama T, Kanmura Y, Lindahl SG (2016) Atrial natriuretic peptide attenuation of renal ischemia-reperfusion injury after major surgery. J Surg Res 201:213-8.	Rat	Kidney	Kidney
Cecatto 2016 Toxicol In Vitro	2016	Cecatto C, Godoy KD, da Silva JC, Amaral AU, Wajner M (2016) Disturbance of mitochondrial functions provoked by the major long-chain 3-hydroxylated fatty acids accumulating in MTP and LCHAD deficiencies in skeletal muscle. Toxicol In Vitro 36:1-9.	Rat	Skeletal muscle	Skeletal muscle
Docherty 2016 Stem Cell Res Ther	2016	Docherty CK, Salt IP, Mercer JR (2016) Lin28A induces energetic switching to glycolytic metabolism in human embryonic kidney cells. Stem Cell Res Ther 7:78.	Human	Kidney HEK	Kidney HEK
Forte 2016 Sci Rep	2016	Forte E, Borisov VB, Falabella M, Colaço HG, Tinajero-Trejo M, Poole RK, Vicente JB, Sarti P, Giuffrè A (2016) The terminal oxidase cytochrome bd promotes sulfide-resistant bacterial respiration and growth. Sci Rep 6:23788.	Eubacteria
Jardim-Messeder 2016 Anticancer Res	2016	Jardim-Messeder D, Moreira-Pacheco F (2016) 3-Bromopyruvic acid inhibits tricarboxylic acid cycle and glutaminolysis in HepG2 cells. Anticancer Res 36:2233-41.	Mouse	Liver Kidney	Liver Kidney
Sobotka 2016 J Bioenerg Biomembr	2016	Sobotka O, Endlicher R, Drahota Z, Kučera O, Rychtrmoc D, Raad M, Hakeem K, Červinková Z (2016) Impaired mitochondrial functions contribute to 3-bromopyruvate toxicity in primary rat and mouse hepatocytes. J Bioenerg Biomembr 48:363-73.	Mouse Rat	Liver	Liver
Valenzuela 2016 Cell Death Dis	2016	Valenzuela R, Costa-Besada MA, Iglesias-Gonzalez J, Perez-Costas E, Villar-Cheda B, Garrido-Gil P, Melendez-Ferro M, Soto-Otero R, Lanciego JL, Henrion D, Franco R, Labandeira-Garcia JL (2016) Mitochondrial angiotensin receptors in dopaminergic neurons. Role in cell protection and aging-related vulnerability to neurodegeneration. Cell Death Dis 7:e2427.	Mouse Rat	Nervous system	Nervous system
Xia 2016 RSC Adv	2016	Xia Z, Yi X, Zhuang Y (2016) Stable over-expression of the human malate–aspartate NADH shuttle member Aralar I in PK15 cells improves energy metabolism and enhances proliferation of porcine circovirus-2. RSC Adv 6:61268-77.	Pig	Kidney	Kidney
Grundmanova 2016 Physiol Res	2016	Grundmanová M, Jarkovská D, Süß A, Tůma Z, Marková M, Grundman Z, El-Kadi A, Čedíková M, Štengl M, Kuncová J (2016) Propofol-induced mitochondrial and contractile dysfunction of the rat ventricular myocardium. Physiol Res 65:S601-9.	Rat	Heart	Heart
Franko 2016 Diabetes	2016	Franko A, Huypens P, Neschen S, Irmler M, Rozman J, Rathkolb B, Neff F, Prehn C, Dubois G, Baumann M, Massinger R, Gradinger D, Przemeck GK, Repp B, Aichler M, Feuchtinger A, Schommers P, Stöhr O, Sanchez-Lasheras C, Adamski J, Peter A, Prokisch H, Beckers J, Walch AK, Fuchs H, Wolf E, Schubert M, Wiesner RJ, Hrabě de Angelis M (2016) Bezafibrate improves insulin sensitivity and metabolic flexibility in STZ-treated diabetic mice. Diabetes 65:2540-52.	Human	Skeletal muscle Fibroblast	Skeletal muscle Fibroblast
Maarman 2016 J Appl Physiol (1985)	2016	Maarman GJ, Andrew BM, Blackhurst DM, Ojuka EO (2016) Melatonin protects against uric acid-induced mitochondrial dysfunction, oxidative stress, and triglyceride accumulation in C₂C₁₂ myotubes. J Appl Physiol (1985) 122:1003-10.	Mouse	Skeletal muscle	Skeletal muscle
Du 2016 Thesis	2016	Du X (2016) Anthropogenic pollution effects on mitochondrial energy metabolism, gene expression, and genotypes of natural Fundulus heteroclitus populations. Dissertation p175.	Fishes	Liver	Liver
Strifler 2016b PLOS ONE	2016	Strifler G, Tuboly E, Görbe A, Boros M, Pécz D, Hartmann P (2016) Targeting mitochondrial dysfunction with L-alpha glycerylphosphorylcholine. PLOS ONE 11:e0166682.	Rat	Liver	Liver
Fisar 2016b Folia Biol (Praha)	2016	Fisar Z, Hroudova J, Singh N, Koprivova A, Maceckova D (2016) Effect of simvastatin, coenzyme Q10, resveratrol, acetylcysteine and acetylcarnitine on mitochondrial respiration. Folia Biol (Praha) 62:53-66.	Pig	Nervous system	Nervous system
Renner 2016 Mycotoxin Res	2016	Renner L, Kahlert S, Tesch T, Bannert E, Frahm J, Barta-Böszörményi A, Kluess J, Kersten S, Schönfeld P, Rothkötter HJ, Dänicke S (2016) Chronic DON exposure and acute LPS challenge: effects on porcine liver morphology and function. Mycotoxin Res 33:207-18.	Pig	Liver	Liver
Rohlenova 2016 Antioxid Redox Signal	2016	Rohlenova K, Sachaphibulkij K, Stursa J, Bezawork-Geleta A, Blecha J, Endaya B, Werner L, Cerny J, Zobalova R, Goodwin J, Spacek T, Alisadeh E, Yan B, Nguyen M, Vondrusova M, Sobol M, Jezek P, Hozak P, Truksa J, Rohlena J, Dong L, Neuzil J (2016) Selective disruption of respiratory supercomplexes as a new strategy to suppress Her2^high breast cancer. Antioxid Redox Signal 26:84-103.	Human Mouse	Liver Genital Other cell lines	Liver Genital Other cell lines
Kassassir 2016 Chem Biol Interact	2016	Kassassir H, Siewiera K, Talar M, Stec-Martyna E, Pawlowska Z, Watala C (2016) Non-enzymatic modifications of prostaglandin H synthase 1 affect bifunctional enzyme activity - Implications for the sensitivity of blood platelets to acetylsalicylic acid. Chem Biol Interact 253:78-92.	Other mammals
Amaral 2016 Biochim Biophys Acta	2016	Amaral AU, Cecatto C, da Silva JC, Wajner A, Godoy KD, Ribeiro RT, Wajner M (2016) cis-4-Decenoic and decanoic acids impair mitochondrial energy, redox and Ca²⁺ homeostasis and induce mitochondrial permeability transition pore opening in rat brain and liver: Possible implications for the pathogenesis of MCAD deficiency. Biochim Biophys Acta 1857:1363-72.	Rat	Nervous system Liver	Nervous system Liver
Piwonska 2016 Acta Neurobiol Exp (Wars)	2016	Piwońska M, Szewczyk A, Schröder UH, Reymann KG, Bednarczyk P (2016) Effectors of large-conductance calcium-activated potassium channel modulate glutamate excitotoxicity in organotypic hippocampal slice cultures. Acta Neurobiol Exp (Wars) 76:20-31.	Rat	Nervous system	Nervous system
Silva 2016 Thesis	2016	Silva Luana Caroline Schüeler da (2016) Fucoxantina inibe a oxidação de LDL e ativação de macrófagos in vitro. PhD Thesis:93 pp.	Human
Hagl 2016 Neuromolecular Med	2016	Hagl S, Asseburg H, Heinrich M, Sus N, Blumrich EM, Dringen R, Frank J, Eckert GP (2016) Effects of long-term rice bran extract supplementation on survival, cognition and brain mitochondrial function in aged NMRI mice. Neuromolecular Med 18:347-63.	Mouse	Nervous system	Nervous system
Brecht 2016 Toxicol In Vitro	2016	Brecht K, Riebel V, Couttet P, Paech F, Wolf A, Chibout SD, Pognan F, Krähenbühl S, Uteng M (2016) Mechanistic insights into selective killing of OXPHOS-dependent cancer cells by arctigenin. Toxicol In Vitro 40:55-65.	Human	Islet cell;pancreas;thymus	Islet cell;pancreas;thymus
Khmil 2016 International Symposium Mitochondrial Motility	2016	Khmil NV, Mosencov AA, Ovsyannikova TN, Dyachenko VD, Goncharenko MS, Kolomytkin OV, Mironova GD (2016) Influence of oranoselenium compounds on functioning of rat liver mitochondria. International Symposium Mitochondrial Motility 96-100.	Rat	Liver	Liver
Gariani 2016 Hepatology	2016	Gariani K, Menzies KJ, Ryu D, Wegner CJ, Wang X, Ropelle ER, Moullan N, Zhang H, Perino A, Lemos V, Kim B, Park YK, Piersigilli A, Pham TX, Yang Y, Ku SC, Koo SI, Fomitchova A, Cantó C, Schoonjans K, Sauve AA, Lee JY, Auwerx J (2016) Eliciting the mitochondrial unfolded protein response via NAD+ repletion reverses fatty liver disease. Hepatology 63:1190-204.	Mouse	Liver	Liver
Gdynia 2016 Nat Commun	2016	Gdynia G, Sauer SW, Kopitz J, Fuchs D, Duglova K, Ruppert T, Miller M, Pahl J, Cerwenka A, Enders M, Mairbäurl H, Kamiński MM, Penzel R, Zhang C, Fuller JC, Wade RC, Benner A, Chang-Claude J, Brenner H, Hoffmeister M, Zentgraf H, Schirmacher P, Roth W (2016) The HMGB1 protein induces a metabolic type of tumour cell death by blocking aerobic respiration. Nat Commun 7:10764.	Human	Endothelial;epithelial;mesothelial cell Other cell lines	Endothelial;epithelial;mesothelial cell Other cell lines
Pokkunuri 2016 Oxid Med Cell Longev	2016	Pokkunuri I, Ali Q, Asghar M (2016) Grape powder improves age-related decline in mitochondrial and kidney functions in Fischer 344 rats. Oxid Med Cell Longev ID 6135319:8p.	Rat	Kidney	Kidney
Gariani 2016 J Hepatol	2016	Gariani K, Ryu D, Menzies KJ, Yi HS, Stein S, Zhang H, Perino A, Lemos V, Katsyuba E, Jha P, Vijgen S, Rubbia-Brandt L, Kim YK, Kim JT, Kim KS, Shong M, Schoonjans K, Auwerx J (2016) Inhibiting poly ADP-ribosylation increases fatty acid oxidation and protects against fatty liver disease. J Hepatol 66:132-41.	Mouse	Liver	Liver
Yao 2016 Biochem Biophys Res Commun	2016	Yao K, Zhang WW, Yao L, Yang S, Nie W, Huang F (2016) Carvedilol promotes mitochondrial biogenesis by regulating the PGC-1/TFAM pathway in human umbilical vein endothelial cells (HUVECs). Biochem Biophys Res Commun 470:961-6.	Human	Endothelial;epithelial;mesothelial cell HUVEC	Endothelial;epithelial;mesothelial cell HUVEC
Salvi 2016 Oxid Med Cell Longev	2016	Salvi A, Patki G, Khan E, Asghar M, Salim S (2016) Protective effect of tempol on buthionine sulfoximine (BSO)-induced mitochondrial impairment in hippocampal derived HT22 cells. Oxid Med Cell Longev 2016:5059043.	Mouse	Nervous system Other cell lines	Nervous system Other cell lines
Barison 2016 J Bioenerg Biomembr	2016	Barisón MJ, Damasceno FS, Mantilla BS, Silber AM (2016) The active transport of histidine and its role in ATP production in Trypanosoma cruzi. J Bioenerg Biomembr 48:437-49.	Protists
Berschneider 2016 Thesis	2016	Berschneider K (2016) Connecting the functions of the proteasome and mitochondria in the lung. Dissertation p161.	Mouse	Lung;gill	Lung;gill
Dungel 2015 Free Radic Biol Med	2015	Dungel P, Perlinger M, Weidinger A, Redl H, Kozlov AV (2015) The cytoprotective effect of nitrite is based on the formation of dinitrosyl iron complexes. Free Radic Biol Med 89:300-10.	Rat	Liver	Liver
Laudien 2015 PhD Thesis	2015	Laudien J (2015) Biologische Verträglichkeit künstlicher Sauerstoffträger auf Perfluorcarbon-Basis. PhD Thesis 1-137.	Rat
Suarez 2015 PhD Thesis	2015	Suárez Cunza S (2015) Actividad captadora de Radicales libres y Effecto antioxidante de Metabolitos secundarios del extracto acuoso des "Allium sativum" var. Huaralino (Ajo) en Modelos in vitro. PhD Thesis 1-39.	Rat	Liver	Liver
Ma 2015 Int J Biol Sci	2015	Ma W, Jing L, Valladares A, Mehta SL, Wang Z, Li PA, Bang JJ (2015) Silver nanoparticle exposure induced mitochondrial stress, caspase-3 activation and cell death: amelioration by sodium selenite. Int J Biol Sci 11:860-7.	Mouse	Nervous system Other cell lines	Nervous system Other cell lines
Burtscher 2015 Mitochondrion	2015	Burtscher J, Zangrandi L, Schwarzer C, Gnaiger E (2015) Differences in mitochondrial function in homogenated samples from healthy and epileptic specific brain tissues revealed by high-resolution respirometry. Mitochondrion 25:104-12.	Mouse	Nervous system	Nervous system
Margulies 2015 Brain Pathol	2015	Margulies SS, Kilbaugh T, Sullivan S, Smith C, Propert K, Byro M, Saliga K, Costine BA, Duhaime AC (2015) Establishing a clinically relevant large animal model platform for TBI therapy development: using Cyclosporin A as a case study. Brain Pathol 25:289-303.	Pig	Nervous system	Nervous system