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Difference between revisions of "OctPGMS pathway control state"

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(Created page with "{{MitoPedia |abbr=PGMSOct |description='''PGMSOct''': Pyruvate & Glutamate & Malate & Succinate & Octanoylcarnitine is a substrate combination which supports convergent electron ...")
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{{MitoPedia
{{MitoPedia
|abbr=PGMSOct
|abbr=OctPGMS
|description='''PGMSOct''': Pyruvate & Glutamate & Malate & Succinate & Octanoylcarnitine is a substrate combination which supports convergent electron flow through CI<small>&</small>II<small>&</small>FAO.
|description='''OctPGMS''': [[Octanoylcarnitine]] & [[Pyruvate]] & [[Glutamate]] & [[Malate]] & [[Succinate]].
|info=[[MiPNet21.06 SUIT reference assay]], [[SUIT-RP1]], [[SUIT-RP2]]
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'''MitoPathway control state:''' [[FNS]]
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'''SUIT protocol:''' [[SUIT-001]], [[SUIT-002]], [[SUIT-015]]
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This substrate combination supports convergent electron flow to the [[Q-junction]].
|info=[[MiPNet21.06 SUIT RP]], [[SUIT reference protocol]]
}}
}}
{{MitoPedia methods}}
::: ''More details''
{{MitoPedia topics
::::Β» [[FNS]]
|mitopedia topic=Respiratory substrate-coupling state
::::Β» [[Additive effect of convergent electron flow]]
}}
::::Β» [[Respiratory_complexes#Respiratory_complexes_-_more_than_five |Respiratory complexes - more than five]]
== PGMSOct(L) ==
::::Β» [[OctPGM pathway control state]]
::::Β» [[Convergent electron flow]]


== PGMSOct(P) ==
== OctPMS<sub>''L''</sub> ==
* [[SUIT-RP2]]_'''6S''': 1D 2Oct 3Mtit 3c (3NADH) 4P 5G '''6S''' 7U 8Gp 9Rot 10Ama 11Tm 12Azd'''
FNS pathway in the LEAK state can be evaluated in the following SUIT protocols:
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== PGMSOctGp(E) ==
* [[SUIT-RP1]]_'''6S''': 1PM 2D 2c (2NADH) 3U 4Oct 5G '''6S''' 7Rot 8Gp 9Ama 10Tm 11Azd
* [[SUIT-RP2]]_'''7U''': 1D 2Oct 3Mtit 3c (3NADH) 4P 5G 6S '''7U''' 8Gp 9Rot 10Ama 11Tm 12Azd'''


== OctPMS<sub>''P''</sub> ==
FNS pathway in the OXPHOS state can be evaluated in the following SUIT protocols:
:::*[[SUIT-002]]
::::* DL-Protocol for isolated mitochondria and tissue homogenate (mt): [[SUIT-002 O2 mt D005]]
::::* DL-Protocol for permeabilized fibers (pfi): [[SUIT-002 O2 pfi D006]]
::::* DL-Protocol for permeabilized cells (pce): [[SUIT-002 O2 ce-pce D007]]
:::*[[SUIT-015]]


== OctPMS<sub>''E''</sub> ==
FNS pathway in the ET state can be evaluated in the following SUIT protocols:
:::*[[SUIT-001]]
::::* DL-Protocol for isolated mitochondria and tissue homogenate (mt): [[SUIT-001 O2 mt D001]]
::::* DL-Protocol for permeabilized fibers (pfi): [[SUIT-001 O2 pfi D002]]
::::* DL-Protocol for permeabilized cells (pce): [[SUIT-001 O2 ce-pce D003]]
:::*[[SUIT-015]]
----
----
[[File:SUIT-Reference-Protocol 1.jpg|700px |SUIT RP1]]<br />
[[File:SUIT-Reference-Protocol 1.jpg|700px |SUIT RP1]]<br />
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[[File:SUIT-Reference-Protocol 2.jpg|700px |SUIT RP2]]<br />
[[File:SUIT-Reference-Protocol 2.jpg|700px |SUIT RP2]]<br />
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{{MitoPedia concepts
|mitopedia concept=SUIT state
}}

Latest revision as of 05:01, 19 July 2022


high-resolution terminology - matching measurements at high-resolution


OctPGMS pathway control state

Description

OctPGMS: Octanoylcarnitine & Pyruvate & Glutamate & Malate & Succinate.

MitoPathway control state: FNS

SUIT protocol: SUIT-001, SUIT-002, SUIT-015

This substrate combination supports convergent electron flow to the Q-junction.

Abbreviation: OctPGMS

Reference: MiPNet21.06 SUIT RP, SUIT reference protocol

More details
Β» FNS
Β» Additive effect of convergent electron flow
Β» Respiratory complexes - more than five
Β» OctPGM pathway control state
Β» Convergent electron flow

OctPMSL

FNS pathway in the LEAK state can be evaluated in the following SUIT protocols:

OctPMSP

FNS pathway in the OXPHOS state can be evaluated in the following SUIT protocols:

OctPMSE

FNS pathway in the ET state can be evaluated in the following SUIT protocols:


SUIT RP1


SUIT RP2



MitoPedia concepts: SUIT state