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...Trieu-Van T, Serteyn D, Kiss R, Robiette R (2013) New 5-Aryl-1H-imidazoles display ''in vitro'' antitumor activity against apoptosis-resistant cancer models, ...rowth inhibition profiles with the NCI database compound profiles. The use of transcriptomically characterized melanoma models then enabled us to highlig

|title=Hall A, Meyle KD, Lange MK, Klima M, Sanderhoff M, Dahl C, Abildgaard C, Th ...nse associated with inhibition of (V600E)BRAF is rescued by overexpression of glyceraldehyde-3-phosphate dehydrogenase (GAPDH), providing direct evidence

|title=Makrecka-Kuka M, Dimitrijevs P, Domracheva I, Jaudzems K, Dambrova M, Arsen ...del. Isoselenazolium salts may be a promising platform for the development of potent drug candidates for anticancer therapy that impact mitochondrial pyr

...ser Z, Callewaert G, Koopman WJ, Willems PH, Baekelandt V (2011) Depletion of PINK1 affects mitochondrial metabolism, calcium homeostasis and energy main ...e imaging. Our findings demonstrate a key role for PINK1 in the regulation of mitochondrial homeostasis and energy metabolism under physiological conditi

|title=Falabella M, Forte E, Magnifico MC, Santini P, Arese M, Giuffrè A, Radić ...vidence suggesting that chronic changes in the NO homeostasis and the rise of reactive oxygen species bioavailability can contribute to cell dysfunction

|title=Calvo AC, Pey AL, Ying M, Loer CM, Martinez A (2008) Anabolic function of phenylalanine hydroxylase in ''Caenorhabditis elegans''. FASEB J 22:3046-58 ...er both an important anabolic function of PAH and the change in regulation of the enzyme along evolution.

...(2018) Impaired mitochondrial energetics characterize poor early recovery of muscle mass following hind limb unloading in old mice. J Gerontol A Biol Sc ...g therapeutic targets to improve recovery of muscle mass following periods of disuse in older animals.

|title=Gururaja Rao S, Bednarczyk P, Towheed A, Shah K, Karekar P, Ponnalagu D, Je ...study establishes the presence of BK_Ca channels in mitochondria of ''Drosophila'' and ascertains its novel physiological role in regulating mi

|title=Frederick DW, Davis JG, Dávila A Jr, Agarwal B, Michan S, Puchowicz MA, Na effects are obtained by germline deletion of major

...lmström MH, Tom RZ, Björnholm M, Garcia-Roves PM, Zierath JR (2013) Effect of leptin treatment on mitochondrial function in obese leptin-deficient ''ob/o ...in freshly dissected tissues. Expression of key proteins in the regulation of mitochondrial function was determined.

...dehydrogenase, hGDH2, augments TCA cycle capacity and oxidative metabolism of glutamate during glucose deprivation in astrocytes. Glia 65:474-88. doi: 10 ...ed role of hGDH2 in astrocytes as an important fail-safe during situations of intense glutamatergic activity.

...i Y, Fleming T, Screaton RA, Schuurmans C (2022) Beyond genetics: the role of metabolism in photoreceptor survival, development and repair. Front Cell De ...has been lost in mammals. Thus, re-activating the regenerative properties of Müller glia in mammals represents an exciting new area that integrates res

...er C 3rd, Vasquez H, Taegtmeyer H, Kolonin MG (2022) Anti-diabetic effects of GLP1 analogs are mediated by thermogenic interleukin-6 signaling in adipocy ...ti-diabetic effects of GLP1 analogs are mediated by transient upregulation of IL-6, which activates canonical IL-6R signaling and thermogenesis.

|title=Hancock M, Hafstad AD, Nabeebaccus AA, Catibog N, Logan A, Smyrnias I, Hans ...ants. Cardiomyocyte-specific Nox4-deficient (csNox4KO) mice display a loss of exercise-induced Nrf2 activation, cardiac oxidative stress and reduced exer

...amins on mitochondrial and cholinergic function in the TgF344-AD rat model of Alzheimer's disease. https://doi.org/10.3390/ph14121218 ...ng from AD. This dysfunction can be partially corrected by the application of the "cocktail" which is particularly active in aged rats. We suggest that t

|title=Wall JM, Basu A, Zunica ERM, Dubuisson OS, Pergola K, Broussard JP, Kirwan ...se models generated in this study will be useful for studying the etiology of individual VCP patient mutations and testing potential genetic and/or pharm

...Musiol E, Janas V, Baur S, Lang R, Fromme T (2020) Comparative assessment of purified saponins as permeabilization agents during respirometry. Biochim B ...oup demonstrates the tremendous potential for further functional screening of pure saponins.

...all C, Jones AE, Pusckarich MA, Mastouri R, Lahm T (2017) Randomized trial of inhaled nitric oxide to treat acute pulmonary embolism: the iNOPE trial. Am |abstract=The study hypothesis is that administration of inhaled NO plus oxygen to subjects with

...haszova M, Kobrinsky E, Zorov DB, Sollott SJ (2022) Computational modeling of mitochondrial K+- and H+-driven ATP synthesis. J Mol Cell Cardiol 165:9-18. ...xplores the role played by KHEmito in modulating the energetic performance of mitochondria. The results obtained support the available experimental evide

|title=Ehinger JK, Morota S, Hansson MJ, Gesine P, Elmér E (2016) Mitochondrial r ...uthors performed a refined evaluation of mitochondrial function in 2 types of peripheral blood cells from 14 patients with Huntington’s disease and 21

...Hickey AJR, Renshaw GMC (2019) Mitochondrial plasticity in the cerebellum of two anoxia-tolerant sharks: contrasting responses to anoxia/reoxygenation. ...llatum''; ES) and the grey carpet shark (''Chiloscyllium punctatum''; GCS) display different adaptive responses to prolonged anoxia: while the ES enters energ

...ase inhibitors sodium butyrate and trichostatin a on the energy metabolism of breast cancer cells. Int J Biochem Cell Biol 116:797-808. ...ctively the results show that epigenetic changes associated to acetylation of proteins in general affect the energy metabolism in all cancer cell lines a

...ulation of skeletal muscle mitochondrial metabolism. Thesis The University of Guelph - Canada 139pp. |journal=Thesis The University of Guelph - Canada

...human colorectal cancer and surrounding tissues: alterations in regulation of mitochondrial respiration and metabolic fluxes. Biochem Biophys Rep 4:111- ...rates. Strong differences between the normal and CRC cells in the affinity of their mitochondria for ADP were revealed; the corresponding Km values were

|title=Czerniczyniec A, La Padula P, Bustamante J, Karadayian AG, Lores-Arnaiz S, ...hypoxia would be time-dependent, according to the physiological functions of the brain studied areas. Nitric oxide metabolism and membrane potential cha

...o C, Trias E, Gandelman M, Radi R, Barbeito L, Cassina P (2012) Modulation of astrocytic mitochondrial function by dichloroacetate improves survival and ...o a disease-modifying effect, further supporting the therapeutic potential of mitochondria-targeted drugs in ALS.

...-related traits and mitochondrial function. Int J Obes (Lond) [Ephub ahead of print]. ...ract=Cell diameter, area, and volume are established quantitative measures of adipocyte size. However, these different adipocyte sizing parameters have n

|title=Bastos Sant'Anna Silva AC, Perez Valencia JA, Sciacovelli M, Lalou C, Sarla ...nvironment has an anaplerotic effect that enhances the malignant potential of prostate cancer cells.

...ion and functional properties of mitochondrial FoF1 ATP synthase on models of specific subunits deficiencies. PhD Thesis 94. ...l lines derived from patient tissues. In many cases mitochondrial diseases display threshold behaviour, when genetic defect is phenotypically manifested only

|title=Valera-Alberni M, Joffraud M, Miro-Blanch J, Capellades J, Junza A, Dayon L ...idence that their modulation could be used in the treatment and prevention of metabolic diseases.

...Puurand M, Shevchuk I, Tepp K, Planken A, Kaambre T (2018) The complexity of mitochondrial outer membrane permeability and VDAC regulation by associated ...n of mitochondrial affinity for ADNs is one of the characteristic features of cancer cells. It can be concluded that the binding sites for tubulin and he

...r H, Sandri M, Hussain SNA, Gouspillou G (2023) MYTHO is a novel regulator of skeletal muscle autophagy and integrity. https://doi.org/10.1038/s41467-023 ...the progression of the disease. We conclude that MYTHO is a key regulator of muscle autophagy and integrity.

...ka PW (1991) Skeletal muscle metabolism and work capacity: a 31P-NMR study of Andean natives and lowlanders. J Appl Physiol 70:1963-76. ...whole-body work capacity, 2) the VO2max paradox, and 3) anecdotal reports of exceptional work capacities in indigenous altitude natives.

|title=Martínez-Reyes I, Cardona LR, Kong H, Vasan K, McElroy GS, Werner M, Kihsh ...cytosol were still unable to grow tumours. This suggests that regeneration of NAD+ is not sufficient to drive tumour growth in vivo. Collectively, our fi

...anck T, Bettendorff L, Pirotte B, Serteyn D, de Tullio P (2020) Modulation of mitochondrial respiration rate and calcium-induced swelling by new cromakal ...behave as a mild uncoupling agent and compound 2 is taken as an inhibitor of the mitochondrial electron-transfer chain.

...ture and PCO2 shift metabolic pathways in differentially oxidative tissues of Notothenia rossii. Comp Biochem Physiol B Biochem Mol Biol 166:48-57. ...lisation of liver energy stores. These patterns reflect a limited capacity of N. rossii to reorganise energy metabolism in response to rising temperature

|title=De Lazzari F, Agostini F, Plotegher N, Sandre M, Greggio E, Megighian A, Bu ...dox stress, our study sheds light on a key role of DJ-1 in the maintenance of cellular homeostasis.

|title=[[Image:O2k-Info.png|right|60px|link=About Oroboros|About Oroboros]]DatLab ...ol User]], quality control, data analysis, documentation, and traceability of measurements with the [[Oroboros O2k]].

...alina A, Rumjanek FD(2013) Comparative biochemistry of tumorigenesis: role of mitochondria in the metastatic process. Mitochondr Physiol Network 18.08. ...Amoedo]] [[MiP2013]], [[Laner 2013 Mitochondr Physiol Network MiP2013|Book of Abstracts Open Access]]

...es respiration-dependent processes in the cardiovascular system - New mode of action for caffeine. PLOS Biol 6:e2004408. ...cesses and define an increase in mitochondrial p27 as a new mode of action of caffeine.

...G, Frank J (2013) Curcumin prevents mitochondrial dysfunction in the brain of the senescence-accelerated mouse-prone 8. Neurochem Int 62:595-602. ...ction and curcumin emerges as a promising nutraceutical for the prevention of neurodegenerative diseases that are accompanied or caused by mitochondrial

...hang W, Fu X, Wu Q, Lu Y, Shi J, Zhou S (2019) Icariin-mediated activation of autophagy confers protective effect on rotenone induced neurotoxicity in vi ...12 cells. Collectively, these results suggest that ICA mediated activation of autophagic flux confers a neuroprotective action on ROT-induced neurotoxici

|title=Dobrowolski SF, Sudano C, Phua YL, Tourkova IL, Spridik K, Goetzman ES, Voc ...overy of Pah^enu2 MSCs osteoblast differentiation. Up-regulation of oxidative energy production is required for osteoblasts differentiation. Ou

...uced mitochondrial reactive oxygen species production in peripheral nerves of mice fed a ketogenic diet. Exp Physiol 103:1206-12. ...ction of reactive oxygen species. These new findings highlight the ability of sensory neurons and axons to oxidize fat-based fuel sources and show that t

|title=Insufficient energy provision or increased oxidative stress – what matter ...ing the central stalk of the enzyme, which results in an isolated decrease of ATP synthase content.

...nd the [[O2k-Titration Set]]. The O2k-Core supports all add-on O2k-Modules of the O2k. ...controlled PVDF or PEEK stirrers are integrated in the two-chamber design of the O2k, and a barometric pressure transducer enables automatic oxygen cali

|title=[[File:Iyer.jpg|left|90px|Shilpa Iyer]] A science-based strategy game for u ...edge amongst students. Game based learning methods rely on the application of knowledge to progress, and produce motivated learners. In a society, when l

|title=Coppin L, Jannin A, Ait Yahya E, Thuillier C, Villenet C, Tardivel M, Bongi ...inates the functioning of the ER and mitochondria, preserves the integrity of mitochondrial network and modulates the ER stress response.

|title=Musi N, Valentine JM, Sickora KR, Baeuerle E, Thompson CS, Shen Q, Orr ME ( ...ave broad implications for understanding, and potentially treating, dozens of brain diseases.

...uced mitochondrial reactive oxygen species production in peripheral nerves of mice fed a ketogenic diet. Exp Physiol 103:1206-12. ...ction of reactive oxygen species. These new findings highlight the ability of sensory neurons and axons to oxidize fat-based fuel sources and show that t