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From Bioblast
 YearReferenceCouplingPathwayPreparationOrganismTissue;cell
Shen 2017 Thesis2017Shen NY (2017) Characterizing protein arginine methyltransferase expression, localization, and function during myogenesis. Master's Thesis p106.LEAK
OXPHOS
N
NS
Permeabilized cellsMouseSkeletal muscle
MiPNet21.14 Reference sample HRR2016-10-19
O2k-Protocols

Development of a reference sample for HRR.

LEAK
ROUTINE
OXPHOS
ET
F
N
S
Gp
CIV
NS
Other combinations
ROX
Intact cells
Permeabilized cells
HumanHEK
MiPNet21.13 Comparison mt-preparations2016-10-18
O2k-Protocols

O2k-Protocols: Mitochondrial preparations for HRR.

LEAK
OXPHOS
ET
N
S
NS
ROX
Permeabilized cells
Homogenate
Isolated mitochondria
MouseHeart
MiPNet21.12 Comparison mt respiration media2016-10-18
O2k-Protocols

O2k-MultiSensor: Mitochondrial respiration media for HRR and simultaneous O2k-Fluorometry.

LEAK
ROUTINE
OXPHOS
ET
N
S
NS
ROX
Intact cells
Permeabilized cells
HumanHEK
Bratic 2016 PLoS Genet2016Bratic A, Clemente P, Calvo-Garrido J, Maffezzini C, Felser A, Wibom R, Wedell A, Freyer C, Wredenberg A (2016) Mitochondrial polyadenylation is a one-step process required for mRNA integrity and tRNA maturation. PLoS Genet 12:e1006028.LEAK
OXPHOS
ET
N
CIV
NS
Permeabilized tissueDrosophila
Tunholi 2016 J Invertebr Pathol2016Tunholi VM, Tunholi-Alves VM, Santos AT, Garcia Jda S, Maldonado A Jr, da-Silva WS, Rodrigues Mde L, Pinheiro J (2016) Evaluation of the mitochondrial system in the gonad-digestive gland complex of Biomphalaria glabrata (Mollusca, Gastropoda) after infection by Echinostoma paraensei (Trematoda, Echinostomatidae). J Invertebr Pathol 136:136-41.LEAK
OXPHOS
ET
N
NS
ROX
Permeabilized tissueMolluscsGenital
Schoenenberger 2016 Cancer Res2016SchΓΆnenberger D, Harlander S, Rajski M, Jacobs RA, Lundby AK, Adlesic M, Hejhal T, Wild PJ, Lundby C, Frew IJ (2016) Formation of renal cysts and tumors in Vhl/Trp53-deficient mice requires HIF1Ξ± and HIF2Ξ±. Cancer Res 76:2025-36.OXPHOS
ET
F
N
S
CIV
NS
ROX
Permeabilized tissueMouseNervous system
Kimball 2016 Thesis2016Kimball RL (2016) The role of hypoxia on pyruvate kinase M2, mammalian target of rapamycin, mitochondrial function, and cell invasion in the trophoblast. Master Thesis p55.LEAK
OXPHOS
ET
N
S
NS
ROX
Permeabilized cellsHumanGenital
Other cell lines
Iglesias-Gonzalez 2016 Mol Neurobiol2016Iglesias-GonzÑlez J, SÑnchez-Iglesias S, Beiras-Iglesias A, Méndez-Álvarez E, Soto-Otero R (2016) Effects of aluminium on rat brain mitochondria bioenergetics: an in vitro and in vivo study. Mol Neurobiol 54:563-70.LEAK
OXPHOS
ET
N
S
NS
Isolated mitochondriaRatNervous system
Snook 2016 Am J Physiol Regul Integr Comp Physiol2016Snook LA, MacPherson RE, Monaco CM, Frendo-Cumbo S, Castellani L, Peppler WT, Anderson ZG, Buzelle SL, LeBlanc PJ, Holloway GP, Wright DC (2016) Prior exercise training blunts short term highfat diet induced weight gain. Am J Physiol Regul Integr Comp Physiol 311:R315-24.LEAK
OXPHOS
ET
N
NS
Permeabilized tissueMouseFat
Kontro 2016 Thesis2016Kontro H (2016) Mitochondrial function and sirtuin expression in hippocampus of young and old high and low-capacity runner rats. Master's Thesis p35.LEAK
OXPHOS
ET
N
S
NS
ROX
HomogenateRatNervous system
Sheremet 2016 Biochemistry (Moscow)2016Sheremet NL, Nevinitsyna TA, Zhorzholadze NV, Ronzina IA, Itkis YS, Krylova TD, Tsygankova PG, Malakhova VA, Zakharova EY, Tokarchuk AV, Panteleeva AA, Karger EM, Lyamzaev KG, Avetisov SE (2016) Previously unclassified mutation of mtDNA m.3472T>C: evidence of pathogenicity in Leber’s hereditary optic neuropathy. Biochemistry (Moscow) BM16-078.LEAK
ROUTINE
OXPHOS
ET
N
S
NS
ROX
Permeabilized cells
Intact cells
HumanEndothelial;epithelial;mesothelial cell
Fibroblast
Platelet
Assmann 2016 Cell Rep2016Assmann N, Dettmer K, Simbuerger JM, Broeker C, Nuernberger N, Renner K, Courtneidge H, Klootwijk ED, Duerkop A, Hall A, Kleta R, Oefner PJ, Reichold M, Reinders J (2016) Renal fanconi syndrome is caused by a mistargeting-based mitochondriopathy. Cell Rep 15:1423-9.LEAK
OXPHOS
ET
F
N
S
NS
Other combinations
ROX
Intact cellsPigKidney
Other cell lines
Distefano 2016 J Gerontol A Biol Sci Med Sci2016Distefano G, Standley RA, DubΓ© JJ, Carnero EA, Ritov VB, Stefanovic-Racic M, Toledo FG, Piva SR, Goodpaster BH, Coen PM (2016) Chronological age does not influence ex-vivo mitochondrial respiration and quality control in skeletal muscle. J Gerontol A Biol Sci Med Sci 72:535-42.LEAK
OXPHOS
ET
N
S
NS
Permeabilized tissueHumanSkeletal muscle
Gehrig 2016 Orphanet J Rare Dis2016Gehrig SM, Mihaylova V, Frese S, Mueller SM, Ligon-Auer M, Spengler CM, Petersen JA, Lundby C, Jung HH (2016) Altered skeletal muscle (mitochondrial) properties in patients with mitochondrial DNA single deletion myopath. Orphanet J Rare Dis 11:105.LEAK
OXPHOS
F
N
S
CIV
NS
Other combinations
ROX
Permeabilized tissueHumanSkeletal muscle
Moon 2016 J Biol Chem2016Moon SH, Mancuso DJ, Sims HF, Liu X, Nguyen AL, Yang K, Guan S, Dilthey BG, Jenkins CM, Weinheimer CJ, Kovacs A, Abendschein D, Gross RW (2016) Cardiac myocyte-specific knock-out of calcium-independent phospholipase A2Ξ³ (iPLA2Ξ³) decreases oxidized fatty acids during ischemia/reperfusion and reduces infarct size. J Biol Chem 291:19687-700.LEAK
OXPHOS
F
N
S
NS
Other combinations
ROX
Isolated mitochondriaMouseHeart
Yavari 2016 Cell Metab2016Yavari A, Stocker CJ, Ghaffari S, Wargent ET, Steeples V, Czibik G, Pinter K, Bellahcene M, Woods A, Martinez de Morentin PB, Cansell C, Lam BY, Chuster A, Petkevicius K, Nguyen-Tu MS, Martinez-Sanchez A, Pullen TJ, Oliver PL, Stockenhuber A, Nguyen C, Lazdam M, O'Dowd JF, Harikumar P, Toth M, Beall C, Kyriakou T, Parnis J, Sarma D, Katritsis G, Wortmann DD, Harper AR, Brown LA, Willows R, Gandra S, Poncio V, de Oliveira Figueiredo MJ, Qi NR, Peirson SN, McCrimmon RJ, Gereben B, Tretter L, Fekete C, Redwood C, Yeo GS, Heisler LK, Rutter GA, Smith MA, Withers DJ, Carling D, Sternick EB, Arch JR, Cawthorne MA, Watkins H, Ashrafian H (2016) Chronic activation of Ξ³2 AMPK induces obesity and reduces Ξ² cell function. Cell Metab 23:821-36.LEAK
OXPHOS
ET
N
NS
ROX
HomogenateMouseNervous system
Wijermars 2016 Kidney Int2016Wijermars LG, Schaapherder AF, de Vries DK, Verschuren L, Wuest RC, Kostidis S, Mayboroda OA, Prins F, Ringers J, Bierau J, Bakker JA, Kooistra T, Lindeman JH (2016) Defective postreperfusion metabolic recovery directly associates with incident delayed graft function. Kidney Int 90:181-91.OXPHOSN
S
NS
ROX
Permeabilized tissueHumanKidney
Morad 2016 J Lipid Res2016Morad SA, Ryan TE, Neufer PD, Zeczycki TN, Davis TS, MacDougall MR, Fox TE, Tan SF, Feith DJ, Loughran TP Jr, Kester M, Claxton DF, Barth BM, Deering TG, Cabot MC (2016) Ceramide-tamoxifen regimen targets bioenergetic elements in acute myelogenous leukemia. J Lipid Res 57:1231-42.LEAK
OXPHOS
N
S
NS
Permeabilized cellsHumanBlood cells
Other cell lines
Seiferling 2016 EMBO Rep2016Seiferling D, Szczepanowska K, Becker C, Senft K, Hermans S, Maiti P, KΓΆnig T, Kukat A, Trifunovic A (2016) Loss of CLPP alleviates mitochondrial cardiomyopathy without affecting the mammalian UPRmt. EMBO Rep 17:953-64.LEAK
OXPHOS
ET
N
NS
Isolated mitochondriaMouseHeart
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