E-P control efficiency

high-resolution terminology - matching measurements at high-resolution

E-P control efficiency

Description

The apparent excess E-P capacity factor (E-P coupling control factor), j_ExP = (E-P)/E = 1-P/E, is an expression of the relative limitation of OXPHOS capacity by the capacity of the phosphorylation system. j_ExP = 0.0 when OXPHOS is not limited by the phosphorylation system at zero ETS excess capacity, P=E, when the phosphorylation system does not exert any control over OXPHOS capacity. j_ExP increases with increasing control of the phosphorylation system over OXPHOS capacity. j_ExP = 1 at the limit of zero phosphorylation capacity. The OXPHOS state of mt-preparations is stimulated to ETS by uncoupler titration, which yields the excess E-P capacity, ExP=E-P.

Abbreviation: j_ExP

Reference: Flux control factor, Gnaiger 2014 MitoPathways

MitoPedia concepts: Respiratory control ratio 

Compare

» OXPHOS control ratio, P/E

» Excess E-R capacity factor, j_ExR = (E-R)/E = 1-R/E

» ETS coupling efficiency, j_≈E = 1-L/E