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...PHOS capacity is expressed as the [[OXPHOS-control ratio]] (''P/E'' [[flux control ratio]]). (''2'') OXPHOS capacity is expressed per tissue or cell mass, int == Keywords ==

=== Coupling-control protocol === ...ler titrations after inhibition of respiration by oligomycin in [[coupling-control protocol]]s with living cells yield the sequence of [[ROUTINE respiration]]

...m alterations in mitochondrial content. LEAK control coupling, respiratory control ratio, and oligomycin-induced LEAK respiration, all measures of mitochondri |keywords=High altitude (HA), Exercise capacity

...ail to evaluate even minor alterations in respiratory coupling and pathway control patterns. ...⁺⁾. The [[PB-Module]] extends HRR to PhotoBiology with accurate control of the light intensity and measurement of photosynthesis. The O2k and the N

...) High levels of whole-body energy expenditure are associated with a lower coupling of skeletal muscle mitochondria in C57Bl/6 mice. Metabolism 59:1612-8. ...coenzyme A as substrate. These results indicate that reduced mitochondrial coupling is associated with positive residual energy expenditure and high rates of t

...iethuechter A, Fasching M, Gnaiger E (2011) Coupling control and substrate control of mitochondrial membrane potential and respiration in the mouse brain, and |keywords=High-resolution respirometry, OXPHOS, mitochondrial membrane potential, ROS

...is controlled by cellular energy demand, energy turnover and the degree of coupling to phosphorylation (intrinsic [[uncoupling]] and pathological [[dyscoupling ::::* DL-Protocol for coupling control with living cells and cell viability module (ce-pce): [[SUIT-003 O2 ce-pce

|title=Ragan CI, Hinkle PC (1975) Ion transport and respiratory control in vesicles formed from reduced nicotinamide adenine dinucleotide coenzyme ...y valinomycin plus nigericin and K+ ions. The results indicate that energy coupling can be observed with isolated NADH-coenzyme Q reductase if the enzyme compl

...in complex II-linked respiration. Coupling control ratios showed increased coupling efficiency for both complex I- and II-linked substrates in hypoxia-exposed ...oxygenation period increases substrate-stimulated respiratory capacity and coupling efficiency. Such effects are accompanied by up-regulation of mitochondrial

...loading is related to decreased mitochondrial ROS production and increased coupling efficiency in myocardium of human failing hearts, suggesting a novel pathom |keywords=Heart failure, Heart transplantation, High-resolution respirometry, Left ve

...s reductions in: maximal mitochondrial respiration capacity, mitochondrial coupling and mitochondrial content. |keywords=Mitochondrial content, Mitochondrial coupling, Mitochondrial homeostasis, Mitochondrial respiration, Muscle wasting, Oxid

...LHD, Doerrier C, Moore AL, Rich PR, Gnaiger E (2021) Coupling and pathway control of coenzyme Q redox state and respiration in isolated mitochondria. Bioener ...s determined by cyclic voltammetry. The voltammogram also provides quality control of the Q-sensor and reveals chemical interferences.

...uence of titrations, e.g. NS(GM), NS(PM), FNSGp(PGM). The coupling/patwhay control diagram in the Figure shows a protocol of SUIT category FNS(PM). :* '''Coupling-control protocols''' (CCP) are a special case of SUIT protocols primarily applied t

...cantly lower in burn victims for 1-year postinjury. Mitochondrial coupling control is diminished for up to 2 years postinjury in burn victims, resulting in gr |keywords=skeletal muscle, ucnoupling, burns, trauma

...ower leak respiration and leak-related coupling control ratio than healthy control subjects. There was no significant change in measures of PBMC respiration f |keywords=Mitochondria, Respiratory, Type 2 diabetes, Dysfunction, Peripheral blood m

...l 10d post burn, where both respiratory capacity (''P''<0.05) and coupling control (''P''<0.05) were significantly lower than sham. These data highlight a dif |keywords=Apoptosis, Burn, Hypermetabolism, Mitochondria, Skeletal muscle

...ulations indicated an enzyme defect in β-oxidation, and that mitochondrial coupling efficiency of electron transfer during β-oxidation particularly in fat oxidation (coupling efficiency and relative flux) were found.

...P, Fasching M, Gnaiger E (2011) Mitochondrial membrane potential, coupling control, H₂O₂ production, and the upper limit of mitochondria

...one C, Kante F, Folkow LP, Hazlerigg DG, West AC, Wood SH (2024) Circadian coupling of mitochondria in a deep-diving mammal. J Exp Biol 227:jeb24699. https://d ...sts and found a circadian variation in mitochondrial activity, with higher coupling efficiency of complex I coinciding with the trough of arntl expression. The

...d (direct) channeling of that fraction of ADP to mitochondria. Compared to control, the direct ADP transfer was increased in MDX ventricles. In conclusion, ou |keywords=Mitochondria, Adenosine 5′-triphosphatase, Muscle, Respiration, Regulatio