Cookies help us deliver our services. By using our services, you agree to our use of cookies. More information

User talk:Beno Marija/MitO2 Kit Produktseite

From Bioblast


User talk:Beno Marija/MitO2 Kit Produktseite


Description Cell permeable compound - Mito-CII-Kit, 2 vials; 1 vial of NV118 (25 mg) + 1 vial of NV161 (10 mg)
Product ID 60200-01
Type O2k
MitoPedia: Mito-CII
MitoPedia: Mito-CII


Cell permeable compounds NV118 and NV161 - Mito-CII-Kit


  • The prodrug NV118 is dissolved in DMSO to 1M concentration and stored in aliquots at -20.
  • The prodrug NV161 is dissolved in DMSO to 1M concentration and stored in aliquots at -20.

Publications in the MiPMap
Cell permeable compound - Mito-CII-Kit.

» Bioblast pdf » Versions

Oroboros (2019-03-01) Mitochondr Physiol Network

Abstract: Gnaiger E, Bastos A, Laner V, Passrugger M, NeuroVive Pharmaceutical AB (2019) cell permeable compound - Mito-CII-Kit. Mitochondr Physiol Network 24.03(01):1-2.

(##) The cell permeable compound Mito-CII-Kit is the first generation of NeuroVive Pharmaceutical AB's succinate/malonate prodrugs and was developed to stimulate and inhibit Complex II of the respiratory electron transfer system in intact cells, and will expand the toolbox for evaluating the role of mitochondria in disease.

» Product: Oroboros O2k, O2k-Catalogue

Keywords: Mito-CII-Kit

O2k-Network Lab: AT_Innsbruck_Oroboros, NeuroVive

Compounds of Mito-CII-Kit

The Mito-CII-Kit is composed of equal quantities of the following Compounds:
  • Cell permeable compound NV118
Description: Succinate prodrug: C10H14O8, Molecular weight 262,2g.mol-1
Aliquots per 25 mg

  • Cell permeable compound NV161
Description: Malonate prodrug: C9H12O8, Molecular weight 248,2g.mol-1
Aliquots per 10 mg

  • Reference:
Ehinger JK, Piel S, Ford R, Karlsson M, Sjövall F, Frostner EÅ, Morota S, Taylor RW, Turnbull DM, Cornell C, Moss SJ, Metzsch C, Hansson MJ, Fliri H, Elmér E (2016) Cell-permeable succinate prodrugs bypass mitochondrial complex I deficiency. Nat Commun 7:12317. »Bioblast link« - Original publication introducing Mito-CII.

Expiry date of Mito-CII-Kit compounds (according to NeuroVive)

Before preparation:

  • 3 years in -80° C
  • 1 year in -20° C


  • In DMSO solution
  • at room temperature: 24 hours.
  • at -20° C: for weeks


  • NV-118: 1592635-33-0
  • NV-161: 1432752-62-9

Labels: MiParea: Instruments;methods 

HRR: O2k-Protocol 

O2k-chemicals and media