From Bioblast
US PA Philadelphia Jang DH
| O2k-Network Lab |  Department of Emergency Medicine and Division of Medical Toxicology, Anesthesia and Critical Care Mitochondrial Unit (ACMU) |
|---|---|
| Address | 3501 Civic Center Blvd, 19104 |
| City | Philadelphia |
| State/Prov | Pennsylvania (PA) |
| Country | USA |
| Weblink | https://www.med.upenn.edu/eckmann-lab/ |
| Contact | Jang David H |
| Team | |
| Team previous | Eckmann David M |
| Status | O2k 2016- |
| Oroboros Events | IOC104, MiPschool 2015 |
| Topics | Mitochondrial Bioenergetic in Emergency Medicine and Medical Toxicology |
O2k-Publications
| Published | Reference | |
|---|---|---|
| Greenwood 2024 PLoS One | 2024 | Greenwood JC, Morgan RW, Abella BS, Shofer FS, Baker WB, Lewis A, Ko TS, Forti RM, Yodh AG, Kao SH, Shin SS, Kilbaugh TJ, Jang DH (2024) Carbon monoxide as a cellular protective agent in a swine model of cardiac arrest protocol. PLoS One 19:e0302653. https://doi.org/10.1371/journal.pone.0302653 |
| Janowska 2020 Toxicol In Vitro | 2020 | Janowska JI, Piel S, Saliba N, Kim CD, Jang DH, Karlsson M, Kilbaugh TJ, Ehinger JK (2020) Mitochondrial respiratory chain Complex I dysfunction induced by N-methyl carbamate ex vivo can be alleviated with a cell-permeable succinate prodrug carbamate toxicity and treatment. Toxicol In Vitro 65:104794. |
| Ranganathan 2020 Mitochondrion | 2020 | Ranganathan A, Owiredu S, Jang DH, Eckmann DM (2020) Prophylaxis of mitochondrial dysfunction caused by cellular decompression from hyperbaric exposure . Mitochondrion 52:8-19. |
| Owiredu 2020 Am J Physiol Cell Physiol | 2020 | Owiredu S, Ranganathan A, Eckmann DM, Shofer FS, Hardy K, Lambert DS, Kelly M, Jang DH (2020) Ex vivo use of cell-permeable succinate prodrug attenuates mitochondrial dysfunction in blood cells obtained from carbon monoxide poisoned individuals. Am J Physiol Cell Physiol 319:C129-35. |
| Owiredu 2020 Toxicol Rep | 2020 | Owiredu S, Ranganathan A, Greenwood JC, Piel S, Janowska JI, Eckmann DM, Kelly M, Ehinger JK, Kilbaugh TJ, Jang DH (2020) In vitro comparison of hydroxocobalamin (B12a) and the mitochondrial directed therapy by a succinate prodrug in a cellular model of cyanide poisoning. Toxicol Rep 7:1263-71. |
| Jang 2018 Intensive Care Med Exp | 2018 | Jang DH, MD, Khatri UG, Shortal BP, Kelly M, Lambert DS, Hardy K, Eckmann DM (2018) Alterations in mitochondrial respiration and reactive oxygen species in patients poisoned with carbon monoxide treated with hyperbaric oxygen. Intensive Care Med Exp 6:4. |
| Jang 2018 J Med Toxicol | 2018 | Jang DH, Khatri UG, Mudan A, Love JS, Owiredu S, Eckmann DM (2018) Translational application of measuring mitochondrial functions in blood cells obtained from patients with acute poisoning. J Med Toxicol 14:144-51. |
| Jang 2018 Shock | 2018 | Jang DH, Orloski CJ, Owiredu S, Shofer FS, Greenwood JC, Eckmann DM (2018) Alterations in mitochondrial function in blood cells obtained from patients with sepsis presenting to an emergency department. Shock 51:580-84. |
| Jang 2017 Biol Open | 2017 | Jang DH, Seeger SC, Grady ME, Shofer FC, Eckmann DM (2017) Mitochondrial dynamics and respiration within cells with increased open pore cytoskeletal meshes. Biol Open 6:1831-9. |
| Jang 2017 Clin Toxicol (Phila) | 2017 | Jang DH, Kelly M, Hardy K, Lambert DS, Shofer FS, Eckmann DM (2017) A preliminary study in the alterations of mitochondrial respiration in patients with carbon monoxide poisoning measured in blood cells. Clin Toxicol (Phila) 55:579-84. |
| Jang 2017 Mitochondrion | 2017 | Jang DH, Greenwood JC, Owiredu S, Ranganathan A, Eckmann DM (2017) Mitochondrial networking in human blood cells with application in acute care illnesses. Mitochondrion 44:27-34. |
| Jang 2016 Clin Toxicol (Phila) | 2016 | Jang DH, Shofer FS, Weiss SL, Becker LB (2016) Impairment of mitochondrial respiration following ex vivo cyanide exposure in peripheral blood mononuclear cells. Clin Toxicol (Phila) 54:303-7. |
| Jang 2016 J Intensive Care Med | 2016 | Jang DH, Greenwood JC, Spyres MB, Eckmann D (2016) Measurement of mitochondrial respiration and motility in acute care: sepsis, trauma, and poisoning. J Intensive Care Med 32:86-94. |
O2k-Abstracts
update please
Research
- K08HL136858 (Jang DH, PI) - “Abnormal Mitochondrial Bioenergetic and Motility Signatures in Human Blood Cells as Indices of Acute Poisoning in Patients”
- Penn Acute Research Collaboration-PARC (Jang DH, PI) - “Alterations in mitochondrial bioenergetics and dynamics in blood cells obtained from emergency department patients with sepsis”
Bioblast alert
Visiting scientist in the Oroboros O2k-Laboratory
Jang David H: Visiting scientist at the Oroboros O2k-Laboratory from June 15 to July 15 2016
