Template:SUIT-003 O2 ce D009
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Steps and respiratory states
Step | State | Pathway | Q-junction | Comment - Events (E) and Marks (M) |
---|---|---|---|---|
ce1 | ROUTINE |
ROUTINE respiration in the physiological coupling state R. Externally added permeable substrates could contribute to this respiratory state. | ||
ce2Omy | L | ce1;ce2Omy
Non-phosphorylating resting state (LEAK state); LEAK respiration, Ln, in the presence of oligomycin and absence of ADP, ATP, AMP (no adenylates).
| ||
ce3U | E | ce1;ce2Omy;ce3U
Noncoupled electron transfer state, ET state, with ET capacity E. | ||
ce* | ROX | ce1;ce2Omy;ce3U;ce*
Rox is the residual oxygen consumption in the ROX state, due to oxidative side reactions, estimated either after inhibition of CIII (e.g. antimycin A, myxothiazol), CIV (e.g. Cyanide) or in the absence of endogenous fuel-substrates. Rox is subtracted from oxygen flux as a baseline for all respiratory states, to obtain mitochondrial respiration. |