Difference between revisions of "Pyruvate dehydrogenase"
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{{MitoPedia | {{MitoPedia | ||
|abbr=PDH | |abbr=PDH | ||
|description= | |description='''Pyruvate dehydrogenase''' is the first component enzyme of the [[pyruvate dehydrogenase complex]], which catalyzes oxidative decarboxylation of [[pyruvate]] in the mt-matrix, and yields [[acetyl-CoA]]. PDH is known as the mitochondrial gatekeeper in the core energy pathway of electron flow into the tricarboxylic acid cycle. | ||
|info=[[ | |info=[[Gnaiger 2020 BEC MitoPathways]], [[Hildyard 2003 Biochem J]] | ||
| | }} | ||
{{MitoPedia topics | |||
|mitopedia topic=Enzyme | |||
}} | }} | ||
Latest revision as of 11:12, 7 August 2023
Description
Pyruvate dehydrogenase is the first component enzyme of the pyruvate dehydrogenase complex, which catalyzes oxidative decarboxylation of pyruvate in the mt-matrix, and yields acetyl-CoA. PDH is known as the mitochondrial gatekeeper in the core energy pathway of electron flow into the tricarboxylic acid cycle.
Abbreviation: PDH
Reference: Gnaiger 2020 BEC MitoPathways, Hildyard 2003 Biochem J
MitoPedia topics:
Enzyme