Difference between revisions of "Ebanks 2022 Abstract Bioblast"
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{{Abstract | {{Abstract | ||
|title=<u>Ebanks Brad</u> (2022) Exercise alters mitochondrial physiology and has age-specific impacts on the fitness and lifespan of ''D. melanogaster''. Bioblast 2022: BEC Inaugural Conference. | |title=<u>Ebanks Brad</u> (2022) Exercise alters mitochondrial physiology and has age-specific impacts on the fitness and lifespan of ''D. melanogaster''. Bioblast 2022: BEC Inaugural Conference. | ||
|info=[https://wiki.oroboros.at/index.php/Bioblast_2022#Submitted_abstracts Bioblast 2022: BEC Inaugural Conference] | |info=[https://wiki.oroboros.at/index.php/Bioblast_2022#Submitted_abstracts Bioblast 2022: BEC Inaugural Conference] | ||
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|keywords=Drosophila; ageing; exercise; lifespan; mitochondria; proteomics; respirometry | |keywords=Drosophila; ageing; exercise; lifespan; mitochondria; proteomics; respirometry | ||
}} | }} | ||
== Affiliations == | == Affiliations == | ||
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== List of abbreviations, terms and definitions - MitoPedia == | == List of abbreviations, terms and definitions - MitoPedia == | ||
{{Template:List of abbreviations, terms and definitions - MitoPedia}} | {{Template:List of abbreviations, terms and definitions - MitoPedia}} | ||
{{Labeling | |||
|area=Exercise physiology;nutrition;life style | |||
|diseases=Aging;senescence | |||
|organism=Drosophila | |||
|instruments=Oxygraph-2k | |||
|articletype=Abstract | |||
}} | |||
Revision as of 14:31, 31 May 2022
| Ebanks Brad (2022) Exercise alters mitochondrial physiology and has age-specific impacts on the fitness and lifespan of D. melanogaster. Bioblast 2022: BEC Inaugural Conference. |
Link: Bioblast 2022: BEC Inaugural Conference
Ebanks Brad (2022)
Event: Bioblast 2022
Biological ageing is one of the biggest risk factors for a range of diseases, including cancers, neurodegenerative disease, and heart disease. Mitochondrial dysfunction is associated with both ageing and diseases of ageing. As exercise is increasingly being viewed as a potential anti-ageing therapy, we sought to assess the impact of exercise on the fitness and lifespan of D. melanogaster[1]. In addition, we assessed the exercise-induced changes to mitochondrial physiology through high-resolution respirometry and label-free mass spectrometry. Exercise in late life extends the lifespan of male and female D. melanogaster compared with those exercised throughout their entire lifetime. Exercise also increases Complex-II-linked respiration and upregulates the expression of proteins from the electron transfer Complexes I, III, IV.
• Keywords: Drosophila; ageing; exercise; lifespan; mitochondria; proteomics; respirometry
Affiliations
- University of Nottingham, UK - [email protected]
References
- Ebanks, B. et al (2021) Exercising D. melanogaster modulates the mitochondrial proteome and physiology. The effect on lifespan depends upon age and sex. Int. J. Mol. Sci. 22: 11606. doi:10.3390/ijms222111606
List of abbreviations, terms and definitions - MitoPedia
Labels: MiParea: Exercise physiology;nutrition;life style Pathology: Aging;senescence
Organism: Drosophila
HRR: Oxygraph-2k
