Difference between revisions of "E-P control efficiency"

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E-P control efficiency

Description

The apparent excess E-P capacity factor (E-P coupling control factor), j_ExP = (E-P)/E = 1-P/E, is an expression of the relative limitation of OXPHOS capacity by the capacity of the phosphorylation system. j_ExP = 0.0 when OXPHOS is not limited by the phosphorylation system at zero ETS excess capacity, P=E, when the phosphorylation system does not exert any control over OXPHOS capacity. j_ExP increases with increasing control of the phosphorylation system over OXPHOS capacity. j_ExP = 1 at the limit of zero phosphorylation capacity. The OXPHOS state of mt-preparations is stimulated to ETS by uncoupler titration.

Abbreviation: j_ExP

Reference: Flux control factor, Gnaiger 2014 MitoPathways

MitoPedia methods: Respirometry

MitoPedia topics: "Respiratory control ratio" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property. Respiratory control ratio"Respiratory control ratio" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property.

Compare

Phosphorylation system control ratio
More details: ETS coupling efficiency

List of publications: OXPHOS and ETS

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 {{MitoPedia
 |abbr=''j<sub>ExP</sub>''
-|description=The apparent '''excess ETS capacity factor over ''P''''' (excess ''E-P'' capacity factor; ''E-P'' coupling control factor), ''j<sub>ExP</sub>'' = (''E-P'')/''E'' = 1-''P/E'', is an expression of the relative limitation of [[OXPHOS capacity]] by the capacity of the [[phosphorylation system]]. ''j<sub>ExP</sub>'' = 0.0 when OXPHOS is not limited by the phosphorylation system at zero ETS excess capacity, ''P''=''E'', when the phosphorylation system does not exert any control over OXPHOS capacity. ''j<sub>ExP</sub>'' increases with increasing control of the phosphorylation system over OXPHOS capacity. ''j<sub>ExP</sub>'' = 1 at the limit of zero phosphorylation capacity. The [[OXPHOS]] state of mt-preparations is stimulated to [[ETS]] by [[uncoupler]] titration.
+|description=The apparent '''excess ''E-P'' capacity factor (''E-P'' coupling control factor), ''j<sub>ExP</sub>'' = (''E-P'')/''E'' = 1-''P/E'', is an expression of the relative limitation of [[OXPHOS capacity]] by the capacity of the [[phosphorylation system]]. ''j<sub>ExP</sub>'' = 0.0 when OXPHOS is not limited by the phosphorylation system at zero ETS excess capacity, ''P''=''E'', when the phosphorylation system does not exert any control over OXPHOS capacity. ''j<sub>ExP</sub>'' increases with increasing control of the phosphorylation system over OXPHOS capacity. ''j<sub>ExP</sub>'' = 1 at the limit of zero phosphorylation capacity. The [[OXPHOS]] state of mt-preparations is stimulated to [[ETS]] by [[uncoupler]] titration.
 |info=[[Flux control factor]], [[Gnaiger 2014 MitoPathways]]
 }}