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...potential. With these two properties of mitochondria we can determine the coupling state of respiration and the impact of the mitochondrial substrate on the m ...estigated Complex I and II and a combination of I+II in different coupling control levels.

..., maximal mitochondrial respiratory capacity and oxidative phosphorylation coupling efficiency decreased during acclimation to higher temperatures, suggesting ...=G × E effects, Oroboros Oxygraph 2k, Climate variability hypothesis, Flux control factor, Mitochondrial respiration, Thermal tolerance

...both normoxic and anoxic trout cells, whereas in goldfish hepatocytes the coupling of K+ fluxes was not affected by the rise of Ca2+i |keywords=goldfish, rainbow trout, lactate, cyclosporine A, fructose, metabolic depre

...bo-treated SuHx rats (0.12 ± 0.01 vs. 0.15 ± 0.01 U citrate synthase/mg in control, P < 0.05), and estrogen attenuated the decrease. Mitochondrial quality and |keywords=Cardiopulmonary hemodynamics, Mitochondria, Sex differences

...a kinetic model of homogenous Cyt ''c'' depletion. Comparison to Cyt ''c'' control of respiration in CIR-injured myocardial fibers indicated heterogeneity of |keywords=Heart preservation, Complex I injury, Permeabilized myocardial fibers

...was removed from the diet, the running distance and speed decreased to the control level, despite the improved endurance achieved during nitrate supplementati |keywords=Endurance, Excitation-contraction coupling, Exercise, Oxidative capacity

...(OXPHOS) due to diminished control over it by ADP and impaired functional coupling of adenylate kinase to OXPHOS. In parallel, reduced tissue content of cytoc |keywords=Mitochondria; Overtraining; Oxidative phosphorylation; Rat Myocardium

...nd OXPHOS state and ''P-L'' control efficiency (1-''L''/''P'') compared to control cells, as characterized previously in detail [1]. ...that mitochondria in our model had decreased respiration rate and impaired coupling efficiency, it is important to additionally clarify the relationship betwee

...s, media formulation, living cells, high-resolution respirometry, coupling control, ROUTINE respiration, LEAK respiration, electron transfer capacity, residua |topics=Coupling efficiency;uncoupling

...ared different approaches to assess mitochondrial density and suggest flux control ratios as a valid method to normalize respiration to mitochondrial density. ...significant differences of CI- and CII-linked OXPHOS capacity and coupling control between motor cortex, striatum, hippocampus and pons of naïve mice. CI-lin

...were determined. Mitochondrial respiratory function (assessed by acceptor control ratio (ACR)) was impaired in BMI(L) (2.2+/-0.6) compared with both BMI(N) ( |keywords=COPD

...ectrochemical proton gradient is increased to a maximum, exerting feedback control by depressing oxygen flux to a level determined mainly by the proton leak a ...logical confusion persisting in the scientific literature, the respiratory coupling states of LEAK respiration, [[OXPHOS capacity]] and [[ET capacity]] are dis

...sed at 24 hpf. 70 zebrafish embryos were randomly divided in three groups; Control Group (C); MPTP Group (MPTP), treated with MPTP (600 μM), and aMT Group (a ...f alphasynuclein and iNOS increased in 72 hpf embryos treated with MPTP vs control; this rise was abrogated with the administration of aMT. A significant incr

...d a significant difference in the LEAK respiration state (P<0.05) and LEAK control ratio (P<0.01) between young and old LCR rats (L: 8.83 ± 1.8 vs. 9.67 ± 1 ....67), and CII (r = 0.44; P<0.01 for all), and negatively with the coupling control ratios L/E (r = -0.54) and P/E (r = -0.52; <0.01 for

...mains incomplete without a complementary thermodynamic analysis of kinetic control in energetically coupled pathways. |keywords=Twin-Flow

...xidative phosphorylation or electron transport, LEAK respiration, coupling control, or phosphorylation efficiency. Hypoxia acclimation also had no effect on m |keywords=Energy metabolism, Free radicals, Oxidative stress, Teleost, Ampliflu Red

...pling efficiency were not affected by SuHx or genotype. A higher substrate control ratio for succinate was observed in SuHx fibers and attenuated in ST2<sup>- |keywords=Diaphragm, Mitochondria, Pulmonary hypertension, Respirometry, SU5416

...dox states of Q_ra are sensitive to pathway control and coupling control of mitochondrial electron transfer and [[OXPHOS]]. (''2b'') The Q<sub>ia</s == Keywords ==

...TP/O ratios. Intactness of the outer mitochondrial membrane and functional coupling between mitochondrial creatine kinase and oxidative phosphorylation were ve |keywords=Freeze–thawing, Heart and skeletal muscles, Human biopsies, Mitochondrial

...ned complementary to mitochondrial [[coupling-control state]]s. [[Coupling-control state]]s require [[Electron-transfer-pathway state|ET-pathway competent sta ...are defined in [[mitochondrial preparations]] complementary to [[coupling-control state]]s in mitochondrial physiology.