Chin 2017 US Patent

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Chin MT, Chien WM, Dinca A (2017) Methods for treating and preventing cardiomyopathy. US Patent WO2016094791A1.

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Chin MT, Chien WM, Dinca A (2017) US Patent

Abstract: Methods for treating patients having a cardiomyopathy are provided. Additionally, methods for prophylactically treating patients at risk of developing a cardiomyopathy are provided. Methods for treating patients having, or at risk of developing, a cardiomyopathy may comprise administering a fusion protein including a tafazzin peptide and a cellular permeability peptide to the patient. Further, the tafazzin peptide may be coupled to the cellular permeability peptide by a polypeptide linker.

Bioblast editor: Kandolf G

Labels: MiParea: Respiration, mt-Structure;fission;fusion  Pathology: Inherited, Myopathy 

Organism: Mouse  Tissue;cell: Heart  Preparation: Homogenate 

Coupling state: LEAK, OXPHOS, ET  Pathway: N, CIV, ROX  HRR: Oxygraph-2k 

Labels, 2018-02