Semantic search
From Bioblast
Year | Reference | Mammal and model | Tissue and cell | Stress | Diseases | |
---|---|---|---|---|---|---|
Pereira 2012 BMC Cancer | 2012 | Pereira L, Soares P, Máximo V, Samuels DC (2012) Somatic mitochondrial DNA mutations in cancer escape purifying selection and high pathogenicity mutations lead to the oncocytic phenotype: pathogenicity analysis of reported somatic mtDNA mutations in tumors. BMC Cancer 12:53. | Cancer | |||
Gutierrez 2012 Hum Mutat | 2012 | Gutiérrez Cortés N, Pertuiset C, Dumon E, Börlin M, Hebert-Chatelain E, Pierron D, Feldmann D, Jonard L, Marlin S, Letellier T, Rocher C (2012) Novel mitochondrial DNA mutations responsible for maternally inherited non-syndromic hearing loss. Hum Mutat 33:681-9 | Human | Inherited | ||
Plenge 2012 Front Physiol | 2012 | Plenge U, Belhage B, Guadalupe-Grau A, Andersen PR, Lundby C, Dela F, Stride N, Pott FC, Helge JW, Boushel RC (2012) Erythropoietin treatment enhances muscle mitochondrial capacity in humans. Front Physiol 3:50. | Human | Skeletal muscle | ||
Goo 2012 PLoS One | 2012 | Goo CK, Lim HY, Ho QS, Too HP, Clement MV, Wong KP (2012) PTEN/Akt signaling controls mitochondrial respiratory capacity through 4E-BP1. PLoS One 7:e45806. | Mouse | Fibroblast | ||
Hebert-Chatelain 2012 Biochim Biophys Acta | 2012 | Hebert-Chatelain E, Jose C, Gutierrez Cortes N, Dupuy JW, Rocher C, Dachary-Prigent J, Letellier T (2012) Preservation of NADH ubiquinone-oxidoreductase activity by Src kinase-mediated phosphorylation of NDUFB10. Biochim Biophys Acta 1817:718-725. | Human | Cancer | ||
Galli 2012 J Therm Biol | 2012 | Galli GL, Richards JG (2012) The effect of temperature on mitochondrial respiration in permeabilized cardiac fibers from the freshwater turtle, Trachemys scripta. J Ther Bio 37:195–200. | Reptiles | Heart | ||
Aoun 2012 Br J Nutr | 2012 | Aoun M, Feillet-Coudray C, Fouret G, Chabi B, Crouzier D, Ferreri C, Chatgilialoglu C, Wrutniak-Cabello C, Cristol JP, Carbonneau MA, Coudray C (2012) Rat liver mitochondrial membrane characteristics and mitochondrial functions are more profoundly altered by dietary lipid quantity than by dietary lipid quality: effect of different nutritional lipid patterns. Br J Nutr 107:647-59. | Rat | Liver | Other | |
Wikstroem 2012 Proc Natl Acad Sci U S A | 2012 | Wikström M, Hummer G (2012) Stoichiometry of proton translocation by respiratory complex I and its mechanistic implications. Proc Natl Acad Sci U S A 109:4431-6. | ||||
Welchen 2012 Biochim Biophys Acta | 2012 | Welchen E, Hildebrandt TM, Lewejohann D, Gonzalez DH, Braun HP (2012) Lack of cytochrome c in Arabidopsis decreases stability of Complex IV and modifies redox metabolism without affecting Complexes I and III. Biochim Biophys Acta 1817:990-1001. | Plants | Oxidative stress;RONS | ||
Freyer 2012 Nat Genet | 2012 | Freyer C, Cree LM, Mourier A, Stewart JB, Koolmeister C, Milenkovic D, Wai T, Floros VI, Hagström E, Chatzidaki EE, Wiesner RJ, Samuels DC, Larsson NG, Chinnery PF (2012) Variation in germline mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission. Nat Genet 44:1282-5. | Mouse | Heart Liver | ||
Larsen 2012 Acta Physiol (Oxf) | 2012 | Larsen S, Hey-Mogensen M, Raboel R, Stride N, Helge JW, Dela F (2012) The influence of age and aerobic fitness: Effects on mitochondrial respiration in skeletal muscle. Acta Physiol (Oxf) 205:423-32. | Human | Skeletal muscle | Aging;senescence | |
Distelmaier 2012 Antioxid Redox Signal | 2012 | Distelmaier F, Valsecchi F, Forkink M, van Emst-de Vries S, Swarts HG, Rodenburg RJ, Verwiel ET, Smeitink JA, Willems PH, Koopman WJ (2012) Trolox-sensitive reactive oxygen species regulate mitochondrial morphology, oxidative phosphorylation and cytosolic calcium handling in healthy cells. Antioxid Redox Signal 17:1657-69. | Human | Endothelial;epithelial;mesothelial cell Fibroblast | Oxidative stress;RONS | |
Wuest 2012 Am J Physiol Heart Circ Physiol | 2012 | Wuest RC, Myers DS, Stones R, Benoist D, Robinson PA, Boyle JP, Peers C, White E, Rossiter HB (2012) Regional skeletal muscle remodeling and mitochondrial dysfunction in right ventricular heart failure. Am J Physiol Heart Circ Physiol 302: H402-H411. | Rat | Skeletal muscle | Cryopreservation | |
Aoun 2012 J Bioenerg Biomembr | 2012 | Aoun M, Fouret G, Michel F, Bonafos B, Ramos J, Cristol JP, Carbonneau MA, Coudray C, Feillet-Coudray C (2012) Dietary fatty acids modulate liver mitochondrial cardiolipin content and its fatty acid composition in rats with non alcoholic fatty liver disease. J Bioenerg Biomembr 44:439-52. | Rat | Liver | Other | |
Simonin 2012 Biochem J | 2012 | Simonin V, Galina A (2012) Nitric oxide inhibits succinate dehydrogenase-driven oxygen consumption in potato tuber mitochondria in an oxygen tension-independent manner. Biochem J 449:263-73. | Plants | |||
Usui 2012 Eur J Anaes | 2012 | Usui D, Isaksson M, Suzuki M, Sjovall F, Elmer E, Uchino H (2012) The influence of anesthetic agents on mitochondrial function as determined by high‐resolved respirometry of human blood cells: 9AP7‐9. Eur J Anaes 29:150. | Human | Blood cells Platelet | ||
Halsne 2012 DNA Repair (Amst) | 2012 | Halsne R, Esbensen Y, Wang W, Scheffler K, Suganthan R, Bjoeraas M, Eide L (2012) Lack of the DNA glycosylases MYH and OGG1 in the cancer prone double mutant mouse does not increase mitochondrial DNA mutagenesis. DNA Repair (Amst) 11:278-85. | Mouse | Nervous system | Cancer | |
Lanza 2012 Cell Metab | 2012 | Lanza IR, Zabielski P, Klaus KA, Morse DM, Heppelmann CJ, Bergen HR 3rd, Dasari S, Walrand S, Short KR, Johnson ML, Robinson MM, Schimke JM, Jakaitis DR, Asmann YW, Sun Z, Nair KS (2012) Chronic caloric restriction preserves mitochondrial function in senescence without increasing mitochondrial biogenesis. Cell Metab 16:777-88. | Mouse | Skeletal muscle | Aging;senescence | |
Albertini 2012 Aging (Albany NY) | 2012 | Albertini E, Kozieł R, Duerr A, Neuhaus M, Jansen-Duerr P (2012) Cystathionine beta synthase modulates senescence of human endothelial cells. Aging (Albany NY) 4:664-73. | Human | Endothelial;epithelial;mesothelial cell HUVEC | Aging;senescence | |
Perry 2011 Biochem J | 2011 | Perry CG, Kane DA, Lin CT, Kozy R, Cathey BL, Lark DS, Kane CL, Brophy PM, Gavin TP, Anderson EJ, Neufer PD (2011) Inhibiting myosin-ATPase reveals a dynamic range of mitochondrial respiratory control in skeletal muscle. Biochem J 437:215-22. | Human Rat | Skeletal muscle | ||
Lim 2011 PloS One | 2011 | Lim YA, Grimm A, Giese M, Mensah-Nyagan AG, Villafranca JE, Ittner LM, Eckert A, Götz J (2011) Inhibition of the mitochondrial enzyme ABAD restores the amyloid-β-mediated deregulation of estradiol. PloS One 6:e28887. | Human | Neuroblastoma | Oxidative stress;RONS | Alzheimer's Neurodegenerative |
Naimi 2011 Clin Physiol Funct Imaging | 2011 | Naimi AI, Bourbeau J, Perrault H, Baril J, Wright-Paradis C, Rossi A, Taivassalo T, Sheel AW, Rabøl R, Dela F, Boushel RC (2011) Altered mitochondrial regulation in quadriceps muscles of patients with COPD. Clin Physiol Funct Imaging 31:124-31. | Human | Skeletal muscle | Mitochondrial disease | COPD |
Tepp 2011 Biochim Biophys Acta | 2011 | Tepp K, Shevchuk I, Chekulayev V, Timohhina N, Kuznetsov AV, Guzun R, Saks V, Kaambre T (2011) High efficiency of energy flux controls within mitochondrial interactosome in cardiac intracellular energetic units. Biochim Biophys Acta 1807: 1549-1561. | Heart | |||
Pajuelo-Reguera 2011 J Agric Food Chem | 2011 | Pajuelo-Reguera D, Fernández-Iglesias A, Díaz S, Quesada H, Arola-Arnal A, Bladé C, Salvadó J, Arola L (2011) Improvement of mitochondrial function in muscle of genetically obese rats after chronic supplementation with proanthocyanidins. J Agric Food Chem 59:8491-8. | Rat | Skeletal muscle | Oxidative stress;RONS | |
Kelly 2011 Mitochondrion | 2011 | Kelly OM, McNamara YM, Manzke LH, Meegan MJ, Porter RK (2011) The preservation of in vivo phosphorylated and activated uncoupling protein 3 (UCP3) in isolated skeletal muscle mitochondria following administration of 3,4-methylenedioxymethamphetamine (MDMA aka ecstasy) to rats/mice. Mitochondrion. 12:110-19. | Mouse Rat | Skeletal muscle Liver | ||
Larsen 2011 Acta Physiol (Oxf) | 2011 | Larsen S, Kristensen JM, Stride N, Wojtaszewski JF, Helge JW, Dela F (2011) Skeletal muscle mitochondrial respiration in AMPKα2 kinase-dead mice. Acta Physiol (Oxf) 205: 314-320. | Mouse | Skeletal muscle | ||
Lindfors 2011 Proc Natl Acad Sci U S A | 2011 | Lindfors C, Nilsson IA, Garcia-Roves PM, Zuberi AR, Karimi M, Donahue LR, Roopenian DC, Mulder J, Uhlen M, Ekstroem TJ, Davisson MT, Hoekfelt TG, Schalling M, Johansen JE (2011) Hypothalamic mitochondrial dysfunction associated with anorexia in the anx/anx mouse. Proc Natl Acad Sci U S A 108:18108-13. | Mouse | Nervous system | Oxidative stress;RONS Mitochondrial disease | |
Nakamura 2011 J Biol Chem | 2011 | Nakamura K, Nemani VM, Azarbal F, Skibinski G, Levy JM, Egami K, Munishkina L, Zhang J, Gardner B, Wakabayashi J, Sesaki H, Cheng Y, Finkbeiner S, Nussbaum RL, Masliah E, Edwards RH (2011) Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein alpha-synuclein. J Biol Chem 286:20710-26. | Mouse | Mitochondrial disease | Parkinson's | |
Dungel 2011 J Biochem Mol Toxicol | 2011 | Dungel P, Haindl S, Behling T, Mayer B, Redl H, Kozlov AV (2011) Neither nitrite nor nitric oxide mediate toxic effects of nitroglycerin on mitochondria. J Biochem Mol Toxicol 25:297-302. | Rat | Liver | Oxidative stress;RONS | |
Tello 2011 Cell Metab | 2011 | Tello D, Balsa E, Acosta-Iborra B, Fuertes-Yebra E, Elorza A, Ordóñez Á, Corral-Escariz M, Soro I, López-Bernardo E, Perales-Clemente E, Martínez-Ruiz A, Enríquez JA, Aragonés J, Cadenas S, Landázuri MO (2011) Induction of the mitochondrial NDUFA4L2 protein by HIF-1α decreases oxygen consumption by inhibiting Complex I activity. Cell Metab 14:768-79. | Mouse | Fibroblast | Ischemia-reperfusion Oxidative stress;RONS | |
Viader 2011 J Neurosci | 2011 | Viader A, Golden JP, Baloh RH, Schmidt RE, Hunter DA, Milbrandt J (2011) Schwann cell mitochondrial metabolism supports long-term axonal survival and peripheral nerve function. J Neurosci 31:10128-40. | Mouse | Nervous system | Neurodegenerative | |
Efremov 2011 Nature | 2011 | Efremov RG, Sazanov LA (2011) Structure of the membrane domain of respiratory complex I. Nature 476:414-20. https://doi.org/10.1038/nature10330 | ||||
Kucera 2011 Int J Exp Pathol | 2011 | Kučera O, Lotková H, Staňková P, Podhola M, Roušar T, Mezera V, Cervinková Z (2011) Is rat liver affected by non-alcoholic steatosis more susceptible to the acute toxic effect of thioacetamide?. Int J Exp Pathol 92:281-9. | Rat | Liver | ||
Lotkova 2011 Gen Physiol Biophys | 2011 | Lotková H, Staňková P, Roušar T, Kučera O, Kohoutek L, Mičuda S, Brčáková E, Kolouchová G, Cervinková Z (2011) Deteriorating effect of fluvastatin on the cholestatic liver injury induced by bile duct ligation in rats. Gen Physiol Biophys 30:66-74. | Rat | Oxidative stress;RONS Mitochondrial disease | ||
De Oliveira 2011 Neuroscience | 2011 | de Oliveira J, Hort MA, Moreira EL, Glaser V, Ribeiro-do-Valle RM, Prediger RD, Farina M, Latini A, de Bem AF (2011) Positive correlation between elevated plasma cholesterol levels and cognitive impairments in LDL receptor knockout mice: Relevance of cortico-cerebral mitochondrial dysfunction and oxidative stress. Neuroscience 197:99-106. | Mouse | Nervous system | Oxidative stress;RONS | Alzheimer's Neurodegenerative |
Djafarzadeh 2011 Mitochondrion | 2011 | Djafarzadeh S, Vuda M, Takala J, Ochs M, Jakob SM (2011) Toll-like receptor-3-induced mitochondrial dysfunction in cultured human hepatocytes. Mitochondrion 11:83-8. | Human | Liver | ||
Eberhart 2011 Biochim Biophys Acta | 2011 | Eberhart K, Rainer J, Bindreither D, Ritter I, Gnaiger E, Kofler R, Oefner PJ, Renner K (2011) Glucocorticoid-induced alterations in mitochondrial membrane properties and respiration in childhood acute lymphoblastic leukemia. Biochim Biophys Acta 1807:719-25. | Human | Blood cells | Cancer | |
Guillet 2011 FASEB J | 2011 | Guillet V, Gueguen N, Cartoni R, Chevrollier A, Desquiret V, Angebault C, Amati-Bonneau P, Procaccio V, Bonneau D, Martinou JC, Reynier P (2011) Bioenergetic defect associated with mKATP channel opening in a mouse model carrying a mitofusin 2 mutation. FASEB J 25:1618-27. | Mouse | Nervous system | ||
Bratic 2011 PLoS Genet | 2011 | Bratic A, Wredenberg A, Grönke S, Stewart JB, Mourier A, Ruzzenente B, Kukat C, Wibom R, Habermann B, Partridge L, Larsson NG (2011) The bicoid stability factor controls polyadenylation and expression of specific mitochondrial mRNAs in Drosophila melanogaster. PLoS Genet 7:e1002324. | Drosophila | |||
Niehusmann 2011 Epilepsy Behav | 2011 | Niehusmann P, Surges R, von Wrede RD, Elger CE, Wellmer J, Reimann J, Urbach H, Vielhaber S, Bien CG, Kunz WS (2011) Mitochondrial dysfunction due to Leber's hereditary optic neuropathy as a cause of visual loss during assessment for epilepsy surgery. Epilepsy Behav 20:38-43. | Human | Skeletal muscle Nervous system | Other | |
Angerer 2011 Biochem J | 2011 | Angerer H, Zwicker K, Wumaier Z, Sokolova L, Heide H, Steger M, Kaiser S, Nübel E, Brutschy B, Radermacher M, Brandt U, Zickermann V (2011) A scaffold of accessory subunits links the peripheral arm and the distal proton-pumping module of mitochondrial complex I. https://doi.org/10.1042/bj20110359 | ||||
Hernandez-Mijares 2011 Free Radic Biol Med | 2011 | Hernandez-Mijares A, Rocha M, Apostolova N, Borras C, Jover A, Bañuls C, Sola E, Victor VM (2011) Mitochondrial complex I impairment in leukocytes from type 2 diabetic patients. Free Radic Biol Med 50:1215-21. | Macrophage-derived | Oxidative stress;RONS | Diabetes | |
MiPNet08.15 Complex-I | 2010-08-23 | Laboratory protocol: Complex I (NADH:Ubiquinone Oxidoreductase, EC 1.6.5.3). Mitochondrial membrane enzyme. | ||||
Haack 2010 Nat Genet | 2010 | Haack TB, Danhauser K, Haberberger B, Hoser J, Strecker V, Boehm D, Uziel G, Lamantea E, Invernizzi F, Poulton J, Rolinski B, Iuso A, Biskup S, Schmidt T, Mewes HW, Wittig I, Meitinger T, Zeviani M, Prokisch H (2010) Exome sequencing identifies ACAD9 mutations as a cause of Complex I deficiency. Nat Genet 42:1131-4. | Fibroblast | Other | ||
Hunte 2010 Science | 2010 | Hunte C, Zickermann V, Brandt U (2010) Functional modules and structural basis of conformational coupling in mitochondrial complex I. https://doi.org/10.1126/science.1191046 | ||||
Barksdale 2010 FASEB J | 2010 | Barksdale KA, Perez-Costas E, Gandy JC, Melendez-Ferro M, Roberts RC, Bijur GN (2010) Mitochondrial viability in mouse and human postmortem brain. FASEB J 24:3590-9. | Human Mouse | Nervous system | Cryopreservation Ischemia-reperfusion | |
Koopman 2010 Antioxid Redox Signal | 2010 | Koopman WJ, Nijtmans LG, Dieteren CE, Roestenberg P, Valsecchi F, Smeitink JA, Willems PH (2010) Mammalian mitochondrial complex I: biogenesis, regulation, and reactive oxygen species generation. Antioxid Redox Signal 12:1431-70. | Oxidative stress;RONS | |||
Schoenfeld 2010 Biochim Biophys Acta | 2010 | Schönfeld P, Wieckowski MR, Lebiedzinska M, Wojtczak L (2010) Mitochondrial fatty acid oxidation and oxidative stress: Lack of reverse electron transfer-associated production of reactive oxygen species. Biochim Biophys Acta 1797:929-38. | Rat | Heart | Oxidative stress;RONS | |
Lim 2010 Proteomics | 2010 | Lim YA, Rhein V, Baysang G, Meier F, Poljak A, Raftery MJ, Guilhaus M, Ittner LM, Eckert A, Goetz J (2010) Abeta and human amylin share a common toxicity pathway via mitochondrial dysfunction. Proteomics 10:1621-33. | Human | Nervous system | Oxidative stress;RONS | Aging;senescence Alzheimer's Diabetes Neurodegenerative |
Freyer 2010 Nucleic Acids Res | 2010 | Freyer C, Park CB, Ekstrand MI, Shi Y, Khvorostova J, Wibom R, Falkenberg M, Gustafsson CM, Larsson NG (2010) Maintenance of respiratory chain function in mouse hearts with severely impaired mtDNA transcription. Nucleic Acids Res 38:6577–88. | Mouse | Heart | Cardiovascular | |
Jones 2010 Biochim Biophys Acta | 2010 | Jones TT, Brewer GJ (2010) Age-related deficiencies in Complex I endogenous substrate availability and reserve capacity of Complex IV in cortical neuron electron transport. Biochim Biophys Acta 1797:167-76. | Rat | Nervous system | Aging;senescence Neurodegenerative | |
Xie 2010 Acta Biochim Pol | 2010 | Xie X, Chowdhury SR, Sangle G, Shen GX (2010) Impact of diabetes-associated lipoproteins on oxygen consumption and mitochondrial enzymes in porcine aortic endothelial cells. Acta Biochim Pol 57:393-8. | Pig | Endothelial;epithelial;mesothelial cell | Diabetes | |
Lauritzen 2010 Mol Cell Biol | 2010 | Lauritzen KH, Moldestad O, Eide L, Carlsen H, Nesse G, Storm JF, Mansuy IM, Bergersen LH, Klungland A (2010) Mitochondrial DNA toxicity in forebrain neurons causes apoptosis, neurodegeneration, and impaired behavior. Mol Cell Biol 30:1357-67. | Mouse | Nervous system | Mitochondrial disease | |
Fornunskova 2010 Biochem J | 2010 | Fornuskova D, Stiburek L, Wenchich L, Vinsova K, Hansikova H, Zeman J (2010) Novel insights into the assembly and function of human nuclear-encoded cytochrome c oxidase subunits 4, 5a, 6a, 7a and 7b. Biochem J 428:363-74. | Human | HEK | ||
Chowdhury 2010 Am J Physiol Endocrinol Metab | 2010 | Chowdhury SK, Sangle GV, Xie X, Stelmack GL, Halayko AJ, Shen GX (2010) Effects of extensively oxidized low-density lipoprotein on mitochondrial function and reactive oxygen species in porcine aortic endothelial cells. Am J Physiol Endocrinol Metab 298:E89-98. | Pig | Endothelial;epithelial;mesothelial cell | Oxidative stress;RONS Mitochondrial disease | |
Efremov 2010 Nature | 2010 | Efremov RG, Baradaran R, Sazanov LA (2010) The architecture of respiratory complex I. Nature 465:441-5. https://doi.org/10.1038/nature09066 | ||||
Stankova 2010 Toxicol In Vitro | 2010 | Staňková P, Kučera O, Lotková H, Roušar T, Endlicher R, Cervinková Z (2010) The toxic effect of thioacetamide on rat liver in vitro. Toxicol In Vitro 24:2097-2103. | Liver | Oxidative stress;RONS | ||
Fernyhough 2010 Expert Rev Endocrinol Metab | 2010 | Fernyhough P, Roy Chowdhury SK, Schmidt RE (2010) Mitochondrial stress and the pathogenesis of diabetic neuropathy. Expert Rev Endocrinol Metab 5:39-49. | Rat | Nervous system | Diabetes | |
Nilsson 2010 Thesis | 2010 | Nilsson I (2010) Hypothalmic regulation of food intake – focus on the anx/anx mouse. Thesis Karolinska Institute Stockholm, Department of Molecular Medicine and Sugery, 62 pp. | Mouse | Nervous system | Oxidative stress;RONS | |
Iftikar 2010 JEMBE | 2010 | Iftikar F, MacDonald JR, Hickey AJ (2010) Thermal limits of portunid crab heart mitochondria: Could more thermo-stable mitochondria advantage invasive species? JEMBE 395:232-9. | Crustaceans | Heart | ||
Groeger 2010 Crit Care | 2010 | Groeger M, Wagner F, Baumgart K, Huber-Lang M, Knoeferl M, Georgieff M, Radermacher P, Szabo C, Calzia E (2010) Mitochondrial respiration and cytochrome c inhibition by sulfide in peritoneal macrophages in vitro: Effects of temperature and pH. Crit Care 14:P6. | Macrophage-derived | |||
Korsten 2010 Biochim Biophys Acta | 2010 | Korsten A, de Coo IF, Spruijt L, de Wit LE, Smeets HJ, Sluiter W (2010) Patients with Leber hereditary optic neuropathy fail to compensate impaired oxidative phosphorylation. Biochim Biophys Acta 1797:197-203. | Human | Nervous system Blood cells Lymphocyte | Inherited Neurodegenerative | |
Wang 2010 Stem Cells | 2010 | Wang W, Osenbroch P, Skinnes R, Esbensen Y, Bjoeraas M, Eide L (2010) Mitochondrial DNA integrity is essential for mitochondrial maturation during differentiation of neural stem cells. Stem Cells 28:2195-204. | Nervous system Stem cells | |||
Lim 2009 PlosOne | 2009 | Lim S, Ahn SY, Song IC, Chung MH, Jang HC, Park KS, Lee KU, Pak YK, Lee HK (2009) Chronic exposure to the herbicide, atrazine, causes mitochondrial dysfunction and insulin resistance. PLoS One 4:e5186. | Rat | Skeletal muscle Liver | Mitochondrial disease | |
Nouette-Gaulain 2009 Anesthesiology | 2009 | Nouette-Gaulain K, Bellance N, Prévost B, Passerieux E, Pertuiset C, Galbes O, Smolkova K, Masson F, Miraux S, Delage JP, Letellier T, Rossignol R, Capdevila X, Sztark F (2009) Erythropoietin protects against local anesthetic myotoxicity during continuous regional analgesia. Anesthesiology 110:648-59. | Human Rat | Skeletal muscle Nervous system | ||
Rhein 2009 Cell Mol Neurobiol | 2009 | Rhein V, Baysang G, Rao S, Meier F, Bonert A, Müller-Spahn F, Eckert A (2009) Amyloid-beta leads to impaired cellular respiration, energy production and mitochondrial electron chain complex activities in human neuroblastoma cells. Cell Mol Neurobiol 29:1063-71. | Human | Nervous system Neuroblastoma | Alzheimer's Neurodegenerative | |
Trimmer 2009 Mol Neurodegener | 2009 | Trimmer PA, Schwartz KM, Borland MK, De Taboada L, Streeter J, Oron U (2009) Reduced axonal transport in Parkinson's disease cybrid neurites is restored by light therapy. Mol Neurodegener 4:26. | Human | Nervous system | Parkinson's | |
Distelmaier 2009 Brain | 2009 | Distelmaier F, Koopman WJ, van den Heuvel LP, Rodenburg RJ, Mayatepek E, Willems PH, Smeitink JA (2009) Mitochondrial Complex I deficiency: from organelle dysfunction to clinical disease. Brain 132:833-42. | ||||
Anderson 2009 J Clin Invest | 2009 | Anderson EJ, Lustig ME, Boyle KE, Woodlief TL, Kane DA, Lin C-T, Price JW, Kang L, Rabinovitch PS, Szeto HH, Houmard JA, Cortright RN, Wasserman DH, Neufer PD (2009) Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans. J Clin Invest 119:573-81. | Human Mouse Rat | Skeletal muscle | Oxidative stress;RONS | Diabetes |
Hoffman 2009 J Biol Chem | 2009 | Hoffman DL, Brookes PS (2009) Oxygen sensitivity of mitochondrial reactive oxygen species generation depends on metabolic conditions. J Biol Chem 284:16236-45. | Rat | Oxidative stress;RONS | ||
Larsen 2009 Diabetologia | 2009 | Larsen S, Ara I, Rabøl R, Andersen JL, Boushel RC, Dela F, Helge JW (2009) Are substrate use during exercise and mitochondrial respiratory capacity decreased in arm and leg muscle in type 2 diabetes? Diabetologia 52:1400-8. | Human | Skeletal muscle | Diabetes | |
Raboel 2009 J Clin Endocrinol Metabol | 2009 | Rabøl R, Højberg PM, Almdal T, Boushel R, Haugaard SB, Madsbad S, Dela F (2009) Effect of hyperglycemia on mitochondrial respiration in type 2 diabetes. J Clin Endocrinol Metabol 94:1372-78. | Human | Skeletal muscle | Diabetes | |
Iyer 2009 Mitochondrion | 2009 | Iyer S, Thomas R, Portell F, Dunham L, Quigley C, Bennett JP (2009) Recombinant mitochondrial transcription factor A with N-terminal mitochondrial transduction domain increases respiration and mitochondrial gene expression. Mitochondrion 9:196-203. | Human | Skeletal muscle Nervous system | Inherited | |
Flamment 2009 Am J Physiol Endocrinol Metab | 2009 | Flamment M, Gueguen N, Wetterwald C, Simard G, Malthièry Y, Ducluzeau PH (2009) Effects of the cannabinoid CB1 antagonist rimonabant on hepatic mitochondrial function in rats fed a high-fat diet. Am J Physiol Endocrinol Metab 297:E1162-70. | Rat | Liver | ||
Cassereau 2009 Neurogenetics | 2009 | Cassereau J, Chevrollier A, Gueguen N, Malinge MC, Letournel F, Nicolas G, Richard L, Ferre M, Verny C, Dubas F, Procaccio V, Amati-Bonneau P, Bonneau D, Reynier P (2009) Mitochondrial Complex I deficiency in GDAP1-related autosomal dominant Charcot-Marie-Tooth disease (CMT2K). Neurogenetics 10:145-50. | Human | Nervous system | Inherited Neurodegenerative | |
Droese 2009 Biochim Biophys Acta | 2009 | Dröse S, Hanley PJ, Brandt U (2009) Ambivalent effects of diazoxide on mitochondrial ROS production at respiratory chain Complexes I and III. Biochim Biophys Acta 1790:558-65. | Rat | Heart | Oxidative stress;RONS | |
Borland 2009 Biochim Biophys Acta | 2009 | Borland MK, Mohanakumar KP, Rubinstein JD, Keeney PM, Xie J, Capaldi R, Dunham LD, Trimmer PA, Bennett JP Jr (2009) Relationships among molecular genetic and respiratory properties of Parkinson's disease cybrid cells show similarities to Parkinson's brain tissues. Biochim Biophys Acta 792: 68-74. | Human | Nervous system | Neurodegenerative Parkinson's | |
Osenbroch 2009 FEBS J | 2009 | Osenbroch Poe, Auk-Emblem P, Halsne R, Strand J, Forstroem RJ, van der Pluijm I, Eide L (2009) Accumulation of mitochondrial DNA damage and bioenergetic dysfunction in CSB defective cells. FEBS J 276:2811-21. | Mouse | Aging;senescence Neurodegenerative | ||
Keeney 2009 Exp Neurol | 2009 | Keeney PM, Dunham LD, Quigley CK, Morton SL, Bergquist KE, Bennett JP (2009) Cybrid models of Parkinson's disease show variable mitochondrial biogenesis and genotype-respiration relationships. Exp Neurol 220:374-82. | Human | Blood cells Platelet | Mitochondrial disease | Parkinson's |
King 2009 Biochemistry | 2009 | King MS, Sharpley MS, Hirst J (2009) Reduction of hydrophilic ubiquinones by the flavin in mitochondrial NADH:ubiquinone oxidoreductase (Complex I) and production of reactive oxygen species. Biochemistry 48:2053-62. https://doi.org/10.1021/bi802282h | ||||
Mortiboys 2008 Ann Neurol | 2008 | Mortiboys H, Thomas KJ, Koopman WJ, Klaffke S, Abou-Sleiman P, Olpin S, Wood NW, Willems PH, Smeitink JA, Cookson MR, Bandmann O (2008) Mitochondrial function and morphology are impaired in parkin-mutant fibroblasts. Ann Neurol 64:555-65. | Human | Fibroblast | Parkinson's | |
Cervinkova 2008 Physiol Res | 2008 | Cervinková Z, Rauchová H, Kriváková P, Drahota Z (2008) Inhibition of palmityl carnitine oxidation in rat liver mitochondria by tert-butyl hydroperoxide. Physiol Res 57:133-6. | Liver | Oxidative stress;RONS | ||
Eimre 2008 Biochim Biophys Acta | 2008 | Eimre M, Paju K, Pelloux S, Beraud N, Roosimaa M, Kadaja L, Gruno M, Peet N, Orlova E, Remmelkoor R, Piirsoo A, Saks V, Seppet E (2008) Distinct organization of energy metabolism in HL-1 cardiac cell line and cardiomyocytes. Biochim Biophys Acta 1777:514-24. | Rat | Heart | ||
Gruno 2008 J Gastroenterol | 2008 | Gruno M, Peet N, Tein A, Salupere R, Sirotkina M, Valle J, Peetsalu A, Seppet EK (2008) Atrophic gastritis: deficient complex I of the respiratory chain in the mitochondria of corpus mucosal cells. J Gastroenterol 43:780-8. | Human | Endothelial;epithelial;mesothelial cell | Mitochondrial disease | |
Kulawiak 2008 Exp Neurol | 2008 | Kulawiak B, Kudin AP, Szewczyk A, Kunz WS (2008) BK channel openers inhibit ROS production of isolated rat brain mitochondria. Exp Neurol 212:543-7. | Rat | Nervous system | ||
Aragones 2008 Nat Genet | 2008 | Aragonés J, Schneider M, Van Geyte K, Fraisl P, Dresselaers T, Mazzone M, Dirkx R, Zacchigna S, Lemieux H, Jeoung NH, Lambrechts D, Bishop T, Lafuste P, Diez-Juan A, K Harten S, Van Noten P, De Bock K, Willam C, Tjwa M, Grosfeld A, Navet R, Moons L, Vandendriessche T, Deroose C, Wijeyekoon B, Nuyts J, Jordan B, Silasi-Mansat R, Lupu F, Dewerchin M, Pugh C, Salmon P, Mortelmans L, Gallez B, Gorus F, Buyse J, Sluse F, Harris RA, Gnaiger Erich, Hespel P, Van Hecke P, Schuit F, Van Veldhoven P, Ratcliffe P, Baes M, Maxwell P, Carmeliet P (2008) Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism. Nat Genet 40:170-80. | Mouse | Skeletal muscle | Ischemia-reperfusion Oxidative stress;RONS | |
Juellig 2008 Proteomics | 2008 | Jüllig M, Hickey AJ, Chai CC, Skea GL, Middleditch MJ, Costa S, Choong SY, Philips AR, Cooper GJ (2008) Is the failing heart out of fuel or a worn engine running rich? A study of mitochondria in old spontaneously hypertensive rats. Proteomics 8:2556-72. | Rat | Heart | Mitochondrial disease | |
Regueira 2008 Crit Care Med | 2008 | Regueira T, Baenziger B, Djafarzadeh S, Brandt S, Gorrasi J, Takala J, Lepper PM, Jakob SM (2008) Norepinephrine to increase blood pressure in endotoxaemic pigs is associated with improved hepatic mitochondrial respiration. Crit Care Med 12:R88 | Pig | Liver | ||
De Cavanagh 2008 Exp Gerontol | 2008 | de Cavanagh EM, Flores I, Ferder M, Inserra F, Ferder L (2008) Renin-angiotensin system inhibitors protect against age-related changes in rat liver mitochondrial DNA content and gene expression. Exp Gerontol 43:919-28. | Rat | Liver | Oxidative stress;RONS | Aging;senescence |
Hoepken 2007 Neurobiol Dis | 2007 | Hoepken HH, Gispert S, Morales B, Wingerter O, Del Turco D, Mülsch A, Nussbaum RL, Müller K, Dröse S, Brandt U, Deller T, Wirth B, Kudin AP, Kunz WS, Auburger G (2007) Mitochondrial dysfunction, peroxidation damage and changes in glutathione metabolism in PARK6. Neurobiol Dis 25:401-11. | Human | Fibroblast | Oxidative stress;RONS | Neurodegenerative Parkinson's |
Gillardon 2007 Proteomics | 2007 | Gillardon F, Rist W, Kussmaul L, Vogel J, Berg M, Danzer K, Kraut N, Hengerer B (2007) Proteomic and functional alterations in brain mitochondria from Tg2576 mice occur before amyloid plaque deposition. Proteomics 7:605-16. | Mouse | Nervous system | Alzheimer's Neurodegenerative | |
Soller 2007 Mol Pharmacol | 2007 | Soller M, Dröse S, Brandt U, Brüne B, von Knethen A (2007) Mechanism of Thiazolidinedione-dependent cell death in Jurkat T cells. Mol Pharmacol 71:1535-44. | Heart Other cell lines | Oxidative stress;RONS | Cancer | |
McKenzie 2006 J Mol Biol | 2006 | McKenzie M, Lazarou M, Thorburn DR, Ryan MT (2006) Mitochondrial respiratory chain supercomplexes are destabilized in Barth Syndrome patients. J Mol Biol 361:462-9. | Lymphocyte | Cardiovascular Other | ||
Blakely 2006 Pediatr Res | 2006 | Blakely EL, Rennie KJ, Jones L, Elstner M, Chrzanowska-Lightowlers ZMA, White CB, Shield JPH, Pilz DT, Turnbull DM, Poulton J, Taylor RW (2006) Sporadic intragenic inversion of the mitochondrial DNA MTND1 gene causing fatal infantile lactic acidosis. Pediatr Res 59:440-4. | Human | Fibroblast | Mitochondrial disease | |
Galkin 2006 Biochim Biophys Acta | 2006 | Galkin A, Dröse S, Brandt U (2006) The proton pumping stoichiometry of purified mitochondrial Complex I reconstituted into proteoliposomes. Biochim Biophys Acta 1757:1575-81. | Fungi | |||
Safiulina 2006 Toxicol Sci | 2006 | Safiulina D, Peet N, Seppet E, Zharkovsky A, Kaasik A (2006) Dehydroepiandrosterone inhibits Complex I of the mitochondrial respiratory chain and is neurotoxic in vitro and in vivo at high concentrations. Toxicol Sci 93:348-56. | Rat | Nervous system | Neurodegenerative | |
Sharpley 2006 J Biol Chem | 2006 | Sharpley MS, Hirst J (2006) The inhibition of mitochondrial complex I (NADH:ubiquinone oxidoreductase) by Zn2+. J Biol Chem 281:34803-9. https://doi.org/10.1074/jbc.M607389200 | ||||
Maneiro 2005 Ann Rheum Dis | 2005 | Maneiro E, López-Armada MJ, de Andres MC, Caramés B, Martín MA, Bonilla A, Del Hoyo P, Galdo F, Arenas J, Blanco FJ (2005) Effect of nitric oxide on mitochondrial respiratory activity of human articular chondrocyte. Ann Rheum Dis 64:388-95. | Human | Oxidative stress;RONS | ||
Winkler-Stuck 2005 J Neural Transm | 2005 | Winkler-Stuck K, Kirches E, Mawrin C, Dietzmann K, Lins H, Wallesch CW, Kunz WS, Wiedemann FR (2005) Re-evaluation of the dysfunction of mitochondrial respiratory chain in skeletal muscle of patients with Parkinson's disease. J Neural Transm 112:499-518. | Human | Skeletal muscle | Mitochondrial disease | Parkinson's |
Hinchliffe 2005 Science | 2005 | Hinchliffe P, Sazanov LA (2005) Organization of iron-sulfur clusters in respiratory complex I. Science 309:771-4. https://doi.org/10.1126/science.1113988 |