Difference between revisions of "User talk:Beno Marija/MitO2 Kit Produktseite"
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{{Product | {{Product | ||
|description=Cell permeable compound - | |description=Cell permeable compound - Mit-CII-Kit, 2 vials; 1 vial of NV118 (25 mg) + 1 vial of NV161 (10 mg) | ||
|product id=60200-01 | |product id=60200-01 | ||
|product type=O2k | |product type=O2k | ||
|info=[[Image:MitoPedia.jpg|left|60px|link=http://www.bioblast.at/index.php/MitoPedia:_DatLab |MitoPedia: | |info=[[Image:MitoPedia.jpg|left|60px|link=http://www.bioblast.at/index.php/MitoPedia:_DatLab |MitoPedia: Mit-CII]] [[MitoPedia: Mit-CII]] | ||
|product image=[[Image:MiR05-Kit label.png|right|180px]] | |product image=[[Image:MiR05-Kit label.png|right|180px]] | ||
}} | }} | ||
| Line 9: | Line 9: | ||
Compounds | Compounds | ||
== Cell permeable compound - | == Cell permeable compound - Mit-CII-Kit == | ||
{{Publication | {{Publication | ||
|title=[[Image:O2k-Protocols.jpg|right|80px|link=http://wiki.oroboros.at/index.php/O2k-Protocols|O2k-Protocols]] Cell permeable compound - | |title=[[Image:O2k-Protocols.jpg|right|80px|link=http://wiki.oroboros.at/index.php/O2k-Protocols|O2k-Protocols]] Cell permeable compound - Mit-CII-Kit. | ||
|info=[[File:PDF.jpg|100px|link=http://wiki.oroboros.at/images/c/c8/MiPNet22.10_MiR05-Kit.pdf |Bioblast pdf]] » [http://wiki.oroboros.at/index.php/File:MiPNet22.10_MiR05-Kit.pdf Versions] | |info=[[File:PDF.jpg|100px|link=http://wiki.oroboros.at/images/c/c8/MiPNet22.10_MiR05-Kit.pdf |Bioblast pdf]] » [http://wiki.oroboros.at/index.php/File:MiPNet22.10_MiR05-Kit.pdf Versions] | ||
|authors=Oroboros | |authors=Oroboros | ||
|year=2019-03-01 | |year=2019-03-01 | ||
|journal=Mitochondr Physiol Network | |journal=Mitochondr Physiol Network | ||
|abstract=Gnaiger E, Laner V, Passrugger M, NeuroVive Pharmaceutical AB (2019) cell permeable compound - | |abstract=Gnaiger E, Laner V, Passrugger M, NeuroVive Pharmaceutical AB (2019) cell permeable compound - Mit-CII-Kit. Mitochondr Physiol Network 24.03(01):1-2. | ||
(##) The cell permeable compound | (##) The cell permeable compound Mit-CII-Kit is the first generation of NeuroVive Pharmaceutical AB's succinate/malonate prodrugs and was developed to stimulate and inhibit Complex II of the respiratory electron transfer system in intact cells, and will expand the toolbox for evaluating the role of mitochondria in disease. | ||
:» Product: [[Oroboros O2k]], [[Oroboros O2k-Catalogue | O2k-Catalogue]] | :» Product: [[Oroboros O2k]], [[Oroboros O2k-Catalogue | O2k-Catalogue]] | ||
|keywords= | |keywords=Mit-CII-Kit | ||
|mipnetlab=AT_Innsbruck_Oroboros, NeuroVive | |mipnetlab=AT_Innsbruck_Oroboros, NeuroVive | ||
}} | }} | ||
== Compounds of | == Compounds of Mit-CII-Kit == | ||
:::: The | :::: The Mit-CII-Kit is composed of equal quantities of the following Compounds: | ||
::::* '''[[NV118]]''' | ::::* '''[[NV118]]''' | ||
| Line 43: | Line 43: | ||
== Expiry date of | == Expiry date of Mit-CII== | ||
::::# The stability of compounds in DMSO solution at room temperature is for at least 24h. The estimated stability of the compounds in DMSO at -20 would be weeks. The aliquoted 118 and 161 are stable at -20 for 6 months+. The powder is likely stable for much longer. | ::::# The stability of compounds in DMSO solution at room temperature is for at least 24h. The estimated stability of the compounds in DMSO at -20 would be weeks. The aliquoted 118 and 161 are stable at -20 for 6 months+. The powder is likely stable for much longer. | ||
Revision as of 16:21, 19 March 2019
User talk:Beno Marija/MitO2 Kit Produktseite
| Description | Cell permeable compound - Mit-CII-Kit, 2 vials; 1 vial of NV118 (25 mg) + 1 vial of NV161 (10 mg) |
|---|---|
| Product ID | 60200-01 |
| Type | O2k |
| Link |  |
| Image |  |
Compounds
Cell permeable compound - Mit-CII-Kit
 |
» 
» Versions
Oroboros (2019-03-01) Mitochondr Physiol Network
Abstract: Gnaiger E, Laner V, Passrugger M, NeuroVive Pharmaceutical AB (2019) cell permeable compound - Mit-CII-Kit. Mitochondr Physiol Network 24.03(01):1-2.
(##) The cell permeable compound Mit-CII-Kit is the first generation of NeuroVive Pharmaceutical AB's succinate/malonate prodrugs and was developed to stimulate and inhibit Complex II of the respiratory electron transfer system in intact cells, and will expand the toolbox for evaluating the role of mitochondria in disease.
- » Product: Oroboros O2k, O2k-Catalogue
• Keywords: Mit-CII-Kit
• O2k-Network Lab: AT_Innsbruck_Oroboros, NeuroVive
Compounds of Mit-CII-Kit
- The Mit-CII-Kit is composed of equal quantities of the following Compounds:
-
- Description: Succinate prodrug: C10H14O8, Molecular weight 262,2g.mol-1
- Aliquots per 25 mg
-
- Description: Malonate prodrug: C9H12O8, Molecular weight 248,2g.mol-1
- Aliquots per 10 mg
- Reference:
- Ehinger JK, Piel S, Ford R, Karlsson M, Sjövall F, Frostner EÅ, Morota S, Taylor RW, Turnbull DM, Cornell C, Moss SJ, Metzsch C, Hansson MJ, Fliri H, Elmér E (2016) Cell-permeable succinate prodrugs bypass mitochondrial complex I deficiency. Nat Commun 7:12317. »Bioblast link« - Original publication introducing MitO2.
Expiry date of Mit-CII
- The stability of compounds in DMSO solution at room temperature is for at least 24h. The estimated stability of the compounds in DMSO at -20 would be weeks. The aliquoted 118 and 161 are stable at -20 for 6 months+. The powder is likely stable for much longer.
- CAS-Number 1592635-33-0 for NV-118
- CAS-Number 1432752-62-9 for NV-161
Labels: MiParea: Instruments;methods
HRR: O2k-Protocol
O2k-chemicals and media
