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This page provides a simple browsing interface for finding entities described by a property and a named value. Other available search interfaces include the page property search, and the ask query builder.

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Property "Has-20abstract" (as page type) with input value "-5B-5BImage:MITOEAGLE-2Dlogo.jpg-7Cleft-7C100px-7Clink=http:-2F-2Fwww.mitoeagle.org-2Findex.php-2FMitoEAGLE-7CCOST-20Action-20MitoEAGLE-5D-5D-0AImpaired-20glucose-20tolerance-20and-20insulin-20resistance-20during-20pregnancy-20may-20predispose-20development-20of-20gestational-20diabetes-20mellitus-20(GDM).-20Compromised-20metabolic-20burden-20may-20be-20transmitted-20to-20offspring-20(F1),-20which-20shows-20an-20increased-20risk-20for-20developing-20some-20associated-20metabolic-20disorders,-20including-20non-2Dalcoholic-20fatty-20liver-20disease-20(NAFLD).-20The-20aim-20of-20our-20study-20was-20to-20assess-20the-20effects-20of-20maternal-20physical-20exercise-20(PE)-20during-20pregnancy-20and-20maternal-20diet-20on-20adult-20female-20F1-20(16-20wks-2Dold)-20liver-20mitochondrial-20function-20in-20an-20animal-20model-20of-20GDM-20and-20NAFLD.-0A-0AFemale-20pregnant-20Sprague-2DDawley-20on-20control-20diet-20(C)-20or-20high-2Dfat-20high-2Dsucrose-20diet-20(HFHS)-20were-20submitted-20to-20PE-20during-203-20weeks.-20Oral-20glucose-20tolerance-20test-20was-20performed-20before-20and-20during-20the-20pregnancy-20to-20confirm-20GDM-20metabolic-20alterations.-20All-20F1-20were-20sedentary-20and-20fed-20with-20C.-20F1-20body-20weight-20(BW)-20alterations-20were-20monitored-20weekly.-20Liver-20mitochondrial-20function-20in-2016-20weeks-20old-20female-20F1-20was-20assessed-20using-20complex-20I-20and-20II-2Drelated-20substrates.-0A-0AImpaired-20glucose-20tolerance-20characteristic-20for-20GDM-20was-20observed-20only-20during,-20but-20not-20before-20pregnancy,-20in-20HFHS-20groups,-20regardless-20of-20exercise.-20Moreover,-20maternal-20BW-20gain-20during-20gestation-20was-20increased-20only-20in-20sedentary-20HFHS-20group-20comparing-20to-20C-20group.-20Likewise,-20sedentary-20HFHS-20mothers-20bred-20larger-20litter-20than-20sedentary-20C-20or-20exercised-20HFHS-20mothers.-20Furthermore,-20F1-20of-20HFHS-20mothers-20had-20higher-20after-2Dweaning-20BW-20compared-20to-20F1-20of-20C-20mothers,-20while-20PE-20during-20pregnancy-20lessened-20the-20adverse-20effect-20of-20HFHS-20on-20F1-20BW.-20Regarding-20F1-20liver-20mitochondrial-20function,-20no-20alterations-20were-20found-20in-20complex-20I-2Dsustained-20state-203-20and-20state-204-20respiration.-20While-20the-20respiratory-20control-20ratio-20(RCR)-20with-20complex-20I-0Asubstrates-20was-20decreased-20as-20the-20consequence-20of-20maternal-20HFHS,-20liver-20mitochondrial-20function-20of-20HFHS-2Dmothers’-20F1-20was-20improved-20by-20gestational-20PE.-20No-20alterations-20in-20state-203-2Fstate-204-20respiration,-20and-20RCR-20was-20noticed-20when-20complex-20II-2Drelated-20substrates-20were-20used.-0A-0AMaternal-20HFHS-20induced-20GDM-2Drelated-20glucose-20metabolism-20impairment-20and-20further-20deleteriously-20affected-20after-2Dweaning-20BW,-20as-20well-20as-20liver-20mitochondrial-20function-20in-2016-2Dweeks-20old-20female-20offspring.-20Even-20though-20F1-20was-20not-20submitted-20to-20PE,-20foetal-20exposure-20to-20maternal-20gestational-20PE-20only-20during-203-20weeks-20was-20enough-20to-20protect-20female-20F1-20liver-20mitochondrial-20function-20against-20negative-20impact-20of-20maternal-20fed-20condition." contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.

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