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Souza da Silva 2020 Mol Neurobiol - Revision history
2024-03-29T11:37:02Z
Revision history for this page on the wiki
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https://wiki.oroboros.at/index.php?title=Souza_da_Silva_2020_Mol_Neurobiol&diff=217116&oldid=prev
Cecatto Cristiane at 08:38, 16 April 2021
2021-04-16T08:38:44Z
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Cecatto Cristiane
https://wiki.oroboros.at/index.php?title=Souza_da_Silva_2020_Mol_Neurobiol&diff=209043&oldid=prev
Plangger Mario at 15:43, 30 October 2020
2020-10-30T15:43:13Z
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<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|title=Souza da Silva J, Nonose Y, Rohden F, Lukasewicz Ferreira PC, Fontella FU, Rocha A, Wigner Brochier A, Vieira Apel R, de Lima TM, Seminotti B, Amaral AU, Galina A, Souza DO (2020) Guanosine neuroprotection of presynaptic mitochondrial calcium homeostasis in a mouse study with amyloid-β oligomers. Mol Neurobiol <del style="font-weight: bold; text-decoration: none;">[Epub ahead of print]</del>.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|title=Souza da Silva J, Nonose Y, Rohden F, Lukasewicz Ferreira PC, Fontella FU, Rocha A, Wigner Brochier A, Vieira Apel R, de Lima TM, Seminotti B, Amaral AU, Galina A, Souza DO (2020) Guanosine neuroprotection of presynaptic mitochondrial calcium homeostasis in a mouse study with amyloid-β oligomers. Mol Neurobiol <ins style="font-weight: bold; text-decoration: none;">57:4790-809</ins>.</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|info=[https://www.ncbi.nlm.nih.gov/pubmed/32789760 PMID: 32789760]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|info=[https://www.ncbi.nlm.nih.gov/pubmed/32789760 PMID: 32789760]</div></td></tr>
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Plangger Mario
https://wiki.oroboros.at/index.php?title=Souza_da_Silva_2020_Mol_Neurobiol&diff=206337&oldid=prev
Plangger Mario at 17:10, 21 August 2020
2020-08-21T17:10:57Z
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Plangger Mario
https://wiki.oroboros.at/index.php?title=Souza_da_Silva_2020_Mol_Neurobiol&diff=206336&oldid=prev
Plangger Mario: Plangger Mario moved page Da Silva 2020 Mol Neurobiol to Souza da Silva 2020 Mol Neurobiol without leaving a redirect
2020-08-21T17:05:41Z
<p>Plangger Mario moved page <a href="/index.php?title=Da_Silva_2020_Mol_Neurobiol&action=edit&redlink=1" class="new" title="Da Silva 2020 Mol Neurobiol (page does not exist)">Da Silva 2020 Mol Neurobiol</a> to <a href="/index.php/Souza_da_Silva_2020_Mol_Neurobiol" title="Souza da Silva 2020 Mol Neurobiol">Souza da Silva 2020 Mol Neurobiol</a> without leaving a redirect</p>
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<td colspan="1" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 17:05, 21 August 2020</td>
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Plangger Mario
https://wiki.oroboros.at/index.php?title=Souza_da_Silva_2020_Mol_Neurobiol&diff=206333&oldid=prev
Plangger Mario at 17:04, 21 August 2020
2020-08-21T17:04:16Z
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|info=[https://www.ncbi.nlm.nih.gov/pubmed/32789760 PMID: 32789760]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|info=[https://www.ncbi.nlm.nih.gov/pubmed/32789760 PMID: 32789760]</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|authors=<del style="font-weight: bold; text-decoration: none;">Souzada </del>Silva Jussemara, Nonose Yasmine, Rohden Francieli, Lukasewicz Ferreira Pamela C, Fontella Fernanda Urruth, Rocha Andreia, Wigner Brochier Andressa, Vieira Apel Rodrigo, de Lima Thais Martins, Seminotti Bianca, Umpierrez Amaral Alexandre, Galina Antonio, Souza Diogo O</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|authors=<ins style="font-weight: bold; text-decoration: none;">Souza da </ins>Silva Jussemara, Nonose Yasmine, Rohden Francieli, Lukasewicz Ferreira Pamela C, Fontella Fernanda Urruth, Rocha Andreia, Wigner Brochier Andressa, Vieira Apel Rodrigo, de Lima Thais Martins, Seminotti Bianca, Umpierrez Amaral Alexandre, Galina Antonio, Souza Diogo O</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|year=2020</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|year=2020</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|journal=Mol Neurobiol</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|journal=Mol Neurobiol</div></td></tr>
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Plangger Mario
https://wiki.oroboros.at/index.php?title=Souza_da_Silva_2020_Mol_Neurobiol&diff=206332&oldid=prev
Plangger Mario at 17:04, 21 August 2020
2020-08-21T17:04:02Z
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<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|title=da Silva <del style="font-weight: bold; text-decoration: none;">JS</del>, Nonose Y, Rohden F, Lukasewicz Ferreira PC, Fontella FU, Rocha A, Brochier <del style="font-weight: bold; text-decoration: none;">AW</del>, Apel <del style="font-weight: bold; text-decoration: none;">RV</del>, de Lima TM, Seminotti B, Amaral AU, Galina A, Souza DO (2020) Guanosine neuroprotection of presynaptic mitochondrial calcium homeostasis in a mouse study with amyloid-β oligomers. Mol Neurobiol [Epub ahead of print].</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|title=<ins style="font-weight: bold; text-decoration: none;">Souza </ins>da Silva <ins style="font-weight: bold; text-decoration: none;">J</ins>, Nonose Y, Rohden F, Lukasewicz Ferreira PC, Fontella FU, Rocha A, <ins style="font-weight: bold; text-decoration: none;">Wigner </ins>Brochier <ins style="font-weight: bold; text-decoration: none;">A</ins>, <ins style="font-weight: bold; text-decoration: none;">Vieira </ins>Apel <ins style="font-weight: bold; text-decoration: none;">R</ins>, de Lima TM, Seminotti B, Amaral AU, Galina A, Souza DO (2020) Guanosine neuroprotection of presynaptic mitochondrial calcium homeostasis in a mouse study with amyloid-β oligomers. Mol Neurobiol [Epub ahead of print].</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|info=[https://www.ncbi.nlm.nih.gov/pubmed/32789760 PMID: 32789760]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|info=[https://www.ncbi.nlm.nih.gov/pubmed/32789760 PMID: 32789760]</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|authors=<del style="font-weight: bold; text-decoration: none;">da </del>Silva <del style="font-weight: bold; text-decoration: none;">JS</del>, Nonose <del style="font-weight: bold; text-decoration: none;">Y</del>, Rohden <del style="font-weight: bold; text-decoration: none;">F</del>, Lukasewicz Ferreira <del style="font-weight: bold; text-decoration: none;">PC</del>, Fontella <del style="font-weight: bold; text-decoration: none;">FU</del>, Rocha <del style="font-weight: bold; text-decoration: none;">A</del>, Brochier <del style="font-weight: bold; text-decoration: none;">AW</del>, Apel <del style="font-weight: bold; text-decoration: none;">RV</del>, de Lima <del style="font-weight: bold; text-decoration: none;">TM</del>, Seminotti <del style="font-weight: bold; text-decoration: none;">B</del>, Amaral <del style="font-weight: bold; text-decoration: none;">AU</del>, Galina <del style="font-weight: bold; text-decoration: none;">A</del>, Souza <del style="font-weight: bold; text-decoration: none;">DO</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|authors=<ins style="font-weight: bold; text-decoration: none;">Souzada </ins>Silva <ins style="font-weight: bold; text-decoration: none;">Jussemara</ins>, Nonose <ins style="font-weight: bold; text-decoration: none;">Yasmine</ins>, Rohden <ins style="font-weight: bold; text-decoration: none;">Francieli</ins>, Lukasewicz Ferreira <ins style="font-weight: bold; text-decoration: none;">Pamela C</ins>, Fontella <ins style="font-weight: bold; text-decoration: none;">Fernanda Urruth</ins>, Rocha <ins style="font-weight: bold; text-decoration: none;">Andreia</ins>, <ins style="font-weight: bold; text-decoration: none;">Wigner </ins>Brochier <ins style="font-weight: bold; text-decoration: none;">Andressa</ins>, <ins style="font-weight: bold; text-decoration: none;">Vieira </ins>Apel <ins style="font-weight: bold; text-decoration: none;">Rodrigo</ins>, de Lima <ins style="font-weight: bold; text-decoration: none;">Thais Martins</ins>, Seminotti <ins style="font-weight: bold; text-decoration: none;">Bianca</ins>, <ins style="font-weight: bold; text-decoration: none;">Umpierrez </ins>Amaral <ins style="font-weight: bold; text-decoration: none;">Alexandre</ins>, Galina <ins style="font-weight: bold; text-decoration: none;">Antonio</ins>, Souza <ins style="font-weight: bold; text-decoration: none;">Diogo O</ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|year=2020</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|year=2020</div></td></tr>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|editor=[[Plangger M]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|editor=[[Plangger M]]</div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">|mipnetlab=BR Rio de Janeiro Galina A, BR Rio de Janeiro Institute Biomedical Chemistry, BR Porto Alegre Souza DOG</ins></div></td></tr>
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Plangger Mario
https://wiki.oroboros.at/index.php?title=Souza_da_Silva_2020_Mol_Neurobiol&diff=206331&oldid=prev
Plangger Mario at 16:59, 21 August 2020
2020-08-21T16:59:20Z
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 16:59, 21 August 2020</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{Labeling</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{Labeling</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|area=Respiration</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|area=Respiration<ins style="font-weight: bold; text-decoration: none;">, Pharmacology;toxicology</ins></div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|instruments=Oxygraph-2k</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">|diseases=Alzheimer's</ins></div></td></tr>
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<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|instruments=Oxygraph-2k<ins style="font-weight: bold; text-decoration: none;">, O2k-Fluorometer</ins></div></td></tr>
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Plangger Mario
https://wiki.oroboros.at/index.php?title=Souza_da_Silva_2020_Mol_Neurobiol&diff=206330&oldid=prev
Plangger Mario: Created page with "{{Publication |title=da Silva JS, Nonose Y, Rohden F, Lukasewicz Ferreira PC, Fontella FU, Rocha A, Brochier AW, Apel RV, de Lima TM, Seminotti B, Amaral AU, Galina A, Souza D..."
2020-08-21T15:51:39Z
<p>Created page with "{{Publication |title=da Silva JS, Nonose Y, Rohden F, Lukasewicz Ferreira PC, Fontella FU, Rocha A, Brochier AW, Apel RV, de Lima TM, Seminotti B, Amaral AU, Galina A, Souza D..."</p>
<p><b>New page</b></p><div>{{Publication<br />
|title=da Silva JS, Nonose Y, Rohden F, Lukasewicz Ferreira PC, Fontella FU, Rocha A, Brochier AW, Apel RV, de Lima TM, Seminotti B, Amaral AU, Galina A, Souza DO (2020) Guanosine neuroprotection of presynaptic mitochondrial calcium homeostasis in a mouse study with amyloid-β oligomers. Mol Neurobiol [Epub ahead of print].<br />
|info=[https://www.ncbi.nlm.nih.gov/pubmed/32789760 PMID: 32789760]<br />
|authors=da Silva JS, Nonose Y, Rohden F, Lukasewicz Ferreira PC, Fontella FU, Rocha A, Brochier AW, Apel RV, de Lima TM, Seminotti B, Amaral AU, Galina A, Souza DO<br />
|year=2020<br />
|journal=Mol Neurobiol<br />
|abstract=Amyloid-β oligomers (AβOs) toxicity causes mitochondrial dysfunction, leading to synaptic failure in Alzheimer's disease (AD). Considering presynaptic high energy demand and tight Ca2+ regulation, impairment of mitochondrial function can lead to deteriorated neural activity and cell death. In this study, an AD mouse model induced by ICV (intracerebroventricular) injection of AβOs was used to investigate the toxicity of AβOs on presynaptic function. As a therapeutic approach, GUO (guanosine) was given by oral route to evaluate the neuroprotective effects on this AD model. Following 24 h and 48 h from the model induction, behavioral tasks and biochemical analyses were performed, respectively. AβOs impaired object recognition (OR) short-term memory and reduced glutamate uptake and oxidation in the hippocampus. Moreover, AβOs decreased spare respiratory capacity, reduced ATP levels, impaired Ca2+ handling, and caused mitochondrial swelling in hippocampal synaptosomes. Guanosine crossed the BBB, recovered OR short-term memory, reestablished glutamate uptake, recovered mitochondrial Ca2+ homeostasis, and partially prevented mitochondrial swelling. Therefore, this endogenous purine presented a neuroprotective effect on presynaptic mitochondria and should be considered for further studies in AD models.<br />
|keywords=Alzheimer’s disease, Amyloid-β oligomers, Guanosine, Neuroprotection, Presynaptic mitochondria<br />
|editor=[[Plangger M]]<br />
}}<br />
{{Labeling<br />
|area=Respiration<br />
|instruments=Oxygraph-2k<br />
|additional=2020-08<br />
}}</div>
Plangger Mario