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Respiratory complexes

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Respiratory complexes

Description

Respiratory complexes are membrane-bound enzymes consisting of several subunits which are involved in energy transduction of the respiratory system. The different localizations and functions of the respiratory complexes explain the architecture of the respiratory system. Respiratory complexes of the electron transfer system tansfer electrons to reduce oxygen to water in aerobic respiration, whereas the respiratory complex ATP synthase (CV) is part of the phosphorylation system. Proton translocation couples the electron transfer system to the phosphorylation system. Membrane-spanning respiratory complexes function as proton pumps (in most mitochondria CI, CIII, CIV and CV; in yeast mitochondria CIII, CIV and CV). Respiratory complexes bound to one side of the inner mt-membrane and CI transfer electrons to the Q-junction which separates upstream and downstream segments of the electron transfer system. Electron transfer complexes localized to the inner face of the inner mt-membrane are CII and CETF, and a respiratory complex localized to the outer face of the inner mt-membrane is CGpDH.

Abbreviation: Ci

Reference: Gnaiger 2012 Blue book



MitoPedia topics: Enzyme