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Ratcliffe Peter J

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Name Ratcliffe Peter J, FRS, FMedSci, Nobel Prize in Physiology or Medicine
Institution John Radcliffe Hospital
Address ,
City Oxford
State/Province
Country UK
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Publications

 PublishedReference
Ratcliffe 2022 Clin Med (Lond)2022Ratcliffe PJ (2022) Harveian Oration 2020: Elucidation of molecular oxygen sensing mechanisms in human cells: implications for medicine. https://doi.org/10.7861/clinmed.ed.22.1.harv
Schneider 2010 Gastroenterology2010Schneider M, van Geyte K, Fraisl P, Kiss J, Aragones J, Mazzone M, Mairbaeurl H, Debock K, Ho Jeoung N, Mollenhauer M, Georgiadou M, Bishop T, Roncal C, Sutherland A, Jordan B, Gallez B, Weitz J, Harris RA, Maxwell P, Baes M, Ratcliffe P, Carmeliet P (2010) Loss or silencing of the PHD1 prolyl hydroxylase protects livers of mice against ischemia/referpusion injury. Gastroenterology 138:1143-54.
Aragones 2008 Nat Genet2008Aragonรฉs J, Schneider M, Van Geyte K, Fraisl P, Dresselaers T, Mazzone M, Dirkx R, Zacchigna S, Lemieux H, Jeoung NH, Lambrechts D, Bishop T, Lafuste P, Diez-Juan A, K Harten S, Van Noten P, De Bock K, Willam C, Tjwa M, Grosfeld A, Navet R, Moons L, Vandendriessche T, Deroose C, Wijeyekoon B, Nuyts J, Jordan B, Silasi-Mansat R, Lupu F, Dewerchin M, Pugh C, Salmon P, Mortelmans L, Gallez B, Gorus F, Buyse J, Sluse F, Harris RA, Gnaiger Erich, Hespel P, Van Hecke P, Schuit F, Van Veldhoven P, Ratcliffe P, Baes M, Maxwell P, Carmeliet P (2008) Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism. Nat Genet 40:170-80.
Schofield 2004 Nat Rev Mol Cell Biol2004Schofield CJ, Ratcliffe P (2004) Oxygen sensing by HIF hydroxylases. Nat Rev Mol Cell Biol 5:343-54.
Vaux 2001 Blood2001Vaux EC, Metzen E, Yeates KM, Ratcliffe PJ (2001) Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain. Blood 98(2):296-302.
Maxwell 1999 Nature1999Maxwell PH, Wiesener MS, Chang GW, Clifford SC, Vaux EC, Cockman ME, Wykoff CC, Pugh CW, Maher ER, Ratcliffe PJ (1999) The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. https://doi.org/10.1038/20459

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