Difference between revisions of "R/E control ratio"
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{{MitoPedia | {{MitoPedia | ||
|abbr=''R/E'' | |abbr=''R/E'' | ||
|description=The '''ROUTINE control ratio''' (''R/E'' coupling control ratio) is the ratio of (partially coupled) [[ROUTINE respiration]] and (noncoupled) [[ETS capacity]]. The ''R/E'' control ratio is an expression of how close ROUTINE respiration operates to ETS capacity. | |description=[[Image:R over E.jpg|50 px|link=ROUTINE control ratio|ROUTINE control ratio]] | ||
The '''ROUTINE control ratio''' (''R/E'' coupling control ratio) is the ratio of (partially coupled) [[ROUTINE respiration]] and (noncoupled) [[ETS capacity]]. The ''R/E'' control ratio is an expression of how close ROUTINE respiration operates to ETS capacity. | |||
|info=[[Pesta 2012 Methods Mol Biol]] | |info=[[Pesta 2012 Methods Mol Biol]] | ||
|type=Respiration | |type=Respiration | ||
Revision as of 13:40, 18 January 2015
- high-resolution terminology - matching measurements at high-resolution
R/E control ratio
Description
The ROUTINE control ratio (R/E coupling control ratio) is the ratio of (partially coupled) ROUTINE respiration and (noncoupled) ETS capacity. The R/E control ratio is an expression of how close ROUTINE respiration operates to ETS capacity.
Abbreviation: R/E
Reference: Pesta 2012 Methods Mol Biol
MitoPedia methods:
Respirometry
MitoPedia topics: "Respiratory control ratio" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property.
Respiratory control ratio"Respiratory control ratio" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property.
Boundaries of the ROUTINE control ratio
R/E increases due to (i) high ATP demand and ADP-stimulated ROUTINE respiration, (ii) partial uncoupling, and (iii) limitation of oxidative capacity by defects of substrate oxidation and complexes of the ETS. The corresponding inverse ratio is the uncoupling control ratio, UCR, which can be seen as an index of apparent ETS excess capacity. The lower boundary of R/E is the L/E flux control ratio, whereas the upper boundary is set by the P/E flux control ratio (OXPHOS/ETS capacity).
Biochemical coupling efficiency: from 0 to <1
- More details: »Biochemical coupling efficiency
