Palade 1953 J Histochem Cytochem

Palade GE (1953) An electron microscope study of the mitochondrial structure. J Histochem Cytochem 1: 188-211.

» PMID: 13069686 pdf

Palade GE (1953) J Histochem Cytochem

Abstract: A characteristic pattern of organization was found with the help of the electron microscope in sectioned animal mitochondria irrespective of the species providing the specimen and of the cell type examined.

Each mitochondrion was found to possess:

1. A limiting membrane.
2. A mitochondrial matrix that appears structureless at present levels of resolution.
3. A system of internal ridges (cristae mitochondriales) that protrude from the inside surface of the membrane towards the interior of the organelles. In many mitochondria the cristae are perpendicular to the long axis of the organelles and occur in series within which they lie parallel to one another at more or less regular intervals.

In favorable electron micrographs the mitochondrial membrane appears to be double and the cristae appear to be folds of a second, internal mitochondrial membrane. • Keywords: Mitocondrial structure, Cristae mitocondriales, Double membrane, Protozoa (Euglena gracilis, Poteriochromonas stipitata), Plant cells (leaf tissue of Nicotiana tabaccum and Lemna viridis)

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Organism: Mouse, Rat, Rabbit, Plant"Plant" is not in the list (Human, Pig, Mouse, Rat, Guinea pig, Bovines, Horse, Dog, Rabbit, Cat, ...) of allowed values for the "Mammal and model" property.  Tissue;cell: Skeletal muscle, Liver, Kidney, Endothelial; Epithelial; Mesothelial Cell"Endothelial; Epithelial; Mesothelial Cell" is not in the list (Heart, Skeletal muscle, Nervous system, Liver, Kidney, Lung;gill, Islet cell;pancreas;thymus, Endothelial;epithelial;mesothelial cell, Blood cells, Fat, ...) of allowed values for the "Tissue and cell" property. 

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