View source for Palade 1953 J Histochem Cytochem

{{Publication
|title=Palade GE (1953) An electron microscope study of the mitochondrial structure. J Histochem Cytochem 1:188-211.
|info=[http://jhc.sagepub.com/content/1/4/188.full.pdf+html PMID: 13069686 pdf]
|authors=Palade GE
|year=1953
|journal=J Histochem Cytochem
|abstract=A characteristic pattern of organization was found with the help of the electron microscope in sectioned animal mitochondria irrespective of the species providing the specimen and of the cell type examined.

Each mitochondrion was found to possess:
# A limiting membrane.
# A mitochondrial matrix that appears structureless at present levels of resolution.
# A system of internal ridges (cristae mitochondriales) that protrude from the inside surface of the membrane towards the interior of the organelles. In many mitochondria the cristae are perpendicular to the long axis of the organelles and occur in series within which they lie parallel to one another at more or less regular intervals.
In favorable electron micrographs the mitochondrial membrane appears to be double and the cristae appear to be folds of a second, internal mitochondrial membrane.
|keywords=Mitocondrial structure, Cristae mitocondriales, Double membrane, Protozoa (''Euglena gracilis'', ''Poteriochromonas stipitata''), Plant cells (leaf tissue of ''Nicotiana tabaccum'' and ''Lemna viridis'')
}}
{{Labeling
|organism=Mouse, Rat, Rabbit, Plants, Protists
|tissues=Skeletal muscle, Liver, Kidney, Endothelial;epithelial;mesothelial cell
|additional=Made history
}}