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Oxygen kinetics

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Oxygen kinetics

Description

Oxygen kinetics describes the dependence of respiration of isolated mitochondria or cells on oxygen partial pressure. Frequently, a strictly hyperbolic kinetics is observed, with two parameters, the oxygen pressure at half-maximum flux, p50, and maximum flux, Jmax. The p50 is in the range of 0.2 to 0.8 kPa for cytochrome c oxidase, isolated mitochondria and small cells, strongly dependent on Jmax and coupling state.


Reference: Scandurra_2010_AdvExpMedBiol, www.oroboros.at


MitoPedia methods: Respirometry 



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