Difference between revisions of "Oxygen kinetics"
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|description='''Oxygen kinetics''' describes the dependence of respiration of isolated mitochondria or cells on oxygen partial pressure. Frequently, a strictly hyperbolic kinetics is observed, with two parameters, the oxygen pressure at half-maximum flux, p<sub>50</sub>, and maximum flux, Jmax. The p<sub>50</sub> is in the range of 0.2 to 0.8 kPa for cytochrome c oxidase, isolated mitochondria and small cells, strongly dependent on J<sub>max</sub> and coupling state. | |description='''Oxygen kinetics''' describes the dependence of respiration of isolated mitochondria or cells on oxygen partial pressure. Frequently, a strictly hyperbolic kinetics is observed, with two parameters, the oxygen pressure at half-maximum flux, ''p''<sub>50</sub>, and maximum flux, Jmax. The ''p''<sub>50</sub> is in the range of 0.2 to 0.8 kPa for cytochrome ''c'' oxidase, isolated mitochondria and small cells, strongly dependent on ''J''<sub>max</sub> and coupling state. | ||
|info=[[Scandurra 2010 Adv Exp Med Biol]] | |info=[[Scandurra 2010 Adv Exp Med Biol]] | ||
|type=Respiration | |type=Respiration | ||
Revision as of 20:57, 31 August 2014
- high-resolution terminology - matching measurements at high-resolution
Oxygen kinetics
Description
Oxygen kinetics describes the dependence of respiration of isolated mitochondria or cells on oxygen partial pressure. Frequently, a strictly hyperbolic kinetics is observed, with two parameters, the oxygen pressure at half-maximum flux, p50, and maximum flux, Jmax. The p50 is in the range of 0.2 to 0.8 kPa for cytochrome c oxidase, isolated mitochondria and small cells, strongly dependent on Jmax and coupling state.
Reference: Scandurra 2010 Adv Exp Med Biol
MitoPedia methods:
Respirometry
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