Difference between revisions of "Oxygen kinetics"
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{{MitoPedia | {{MitoPedia | ||
|description=The dependence of respiration of isolated mitochondria or cells on oxygen partial pressure. Frequently, a strictly hyperbolic kinetics is observed, with two parameters, the oxygen pressure at half-maximum flux, p<sub>50</sub>, and maximum flux, Jmax. The p<sub>50</sub> is in the range of 0.2 to 0.8 kPa for cytochrome c oxidase, isolated mitochondria and small cells, strongly dependent on J<sub>max</sub> and coupling state. | |description=The dependence of respiration of isolated mitochondria or cells on oxygen partial pressure. Frequently, a strictly hyperbolic kinetics is observed, with two parameters, the oxygen pressure at half-maximum flux, p<sub>50</sub>, and maximum flux, Jmax. The p<sub>50</sub> is in the range of 0.2 to 0.8 kPa for cytochrome c oxidase, isolated mitochondria and small cells, strongly dependent on J<sub>max</sub> and coupling state. | ||
|info=[http://www.oroboros.at/index.php?oxygenkinetics] | |info=[[Scandurra_2010_AdvExpMedBiol]], [http://www.oroboros.at/index.php?oxygenkinetics www.oroboros.at] | ||
|type=Respiration | |type=Respiration | ||
}} | }} | ||
Revision as of 09:54, 17 September 2010
- high-resolution terminology - matching measurements at high-resolution
Oxygen kinetics
Description
The dependence of respiration of isolated mitochondria or cells on oxygen partial pressure. Frequently, a strictly hyperbolic kinetics is observed, with two parameters, the oxygen pressure at half-maximum flux, p50, and maximum flux, Jmax. The p50 is in the range of 0.2 to 0.8 kPa for cytochrome c oxidase, isolated mitochondria and small cells, strongly dependent on Jmax and coupling state.
Reference: Scandurra_2010_AdvExpMedBiol, www.oroboros.at
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