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Difference between revisions of "Oroboros Laboratory"

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== Oroboros O2k-Laboratory ==
== Oroboros O2k-Laboratory ==
:::: '''40 O2k-Chambers (20 O2k)'''
:::: '''42 O2k-Chambers (21 O2k)'''


:::: The '''Oroboros O2k-Laboratory''' ('Mitochondriales Forschungslabor') is a scientific research laboratory in Innsbruck, Austria, and likely the best equipped lab for high-resolution respirometry (HRR) worldwide. The O2k-Lab was opened during the course of the K-Regio project [[MitoCom_O2k-Fluorometer| MitoCom Tyrol]] in June 2013. It comprises 140 sqm which are divided into the office and research areas.  
:::: The '''Oroboros O2k-Laboratory''' ('Mitochondriales Forschungslabor') is a scientific research laboratory in Innsbruck, Austria, and likely the best equipped lab for high-resolution respirometry (HRR) worldwide. The O2k-Lab was opened during the course of the K-Regio project [[MitoCom_O2k-Fluorometer| MitoCom Tyrol]] in June 2013. It comprises 140 sqm which are divided into the office and research areas.  


::::* Twenty O2k instruments for HRR (40 chambers) equipped with automatic Titration-Injection microPumps and the newest O2k-MultiSensor Modules or the NextGen-O2k configuration are available for research and biomedical applications. The newest instrumental designs are used for rigorous testing of our innovations.
::::* Twenty-one O2k instruments for HRR (42 chambers) equipped with automatic Titration-Injection microPumps and the newest O2k-MultiSensor Modules or the NextGen-O2k configuration are available for research and biomedical applications. The newest instrumental designs are used for rigorous testing of our innovations.


::::* Two additional O2ks (4 chambers) are devoted to instrumental development.
::::* Two additional O2ks (4 chambers) are devoted to instrumental development.
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=== Collaborators in the Oroboros Ecosystem ===
=== Joint projects ===
{| style="color: black;  width: 90%"
{| style="color: black;  width: 90%"
|-
|-
| style="text-align: center;  background-color: #EFF5FB" | '''Collaborations'''
| style="text-align: left;  background-color: #EFF5FB" | '''[[Functional Mitochondrial Diagnostics]]''' (VASCage)
| style="text-align: center;  background-color: #ffffff" |  
| style="text-align: center;  background-color: #ffffff" |  
<gallery heights="165px" mode="nolines" perrow="6" widths="192px">
<gallery heights="165px" mode="nolines" perrow="4" widths="192px">
Image:FischerC.JPG|'''[[Fischer C| Christine Fischer, PhD]]''', PostDoc - [[TissueModels]]
File:Hardorp Rebecka.jpg|'''[[Hardorp Rebecka|Rebecka Hardorp]]'''
File:Torres-QuesadaO.jpg|'''[[Torres-Quesada O|Omar Torres-Quesada, PhD]]''', PostDoc - [[MitoKIN]]
File:Romero Martinez Alejandra.jpeg|'''[[Romero Martinez Alejandra|Alejandra Romero-Martinez, Dr.]]'''
File:Roach_T.jpg|'''[[Roach Thomas|Thomas Roach]]''', PhD
File:Wieser-Insole J.jpg|'''[[Wieser-Insole Joshua|Joshua Wieser-Insole]]'''
File:Profile-icon-9.png|'''[[Pfleger Ana|Ana Pfleger]]'''
</gallery>
|-
| style="text-align: left;  background-color: #ffffff" | '''[[ALAS]]'''
| style="text-align: center;  background-color: #EFF5FB" |
<gallery heights="165px" mode="nolines" perrow="4" widths="192px">
File:Profile-icon-9.png|'''[[Pfleger Ana|Ana Pfleger, Mag. ]]'''
File:Roach_T.jpg|'''[[Roach Thomas|Thomas Roach, PhD ]]'''
</gallery>
|-
| style="text-align: left;  background-color: #EFF5FB" | '''[[TissueModels]]'''
| style="text-align: center;  background-color: #ffffff" |
<gallery heights="165px" mode="nolines" perrow="4" widths="192px">
 
File:Keller M.PNG|'''[[Keller Markus A| Markus Keller, Dr.]]'''
File:IOC 2366 cropped.jpg|'''[[Smaling Anna|Anna Smaling, MRes]]'''
 
</gallery>
|-
| style="text-align: left;  background-color: #ffffff" | '''[[MitoKIN]]'''
| style="text-align: center;  background-color: #EFF5FB" |
<gallery heights="165px" mode="nolines" perrow="4" widths="192px">
File:Stefan E.jpg|'''[[Stefan Eduard|Eduard Stefan, PhD]]'''
File:Profile-icon-9.png|'''[[Strich Sophie|Sophie Strich]]'''
File:Torres-QuesadaO.jpg|'''[[Torres-Quesada O|Omar Torres-Quesada, PhD]]'''
</gallery>
|-
| style="text-align: left;  background-color: #EFF5FB" | '''[[CureMILS]]'''
| style="text-align: center;  background-color: #ffffff" |
<gallery heights="165px" mode="nolines" perrow="4" widths="192px">


File:Suarez.png|'''[[Suarez-Cubero Marta]]''' - [[CureMILS]]
File:Suarez.png|'''[[Suarez-Cubero Marta|Marta Suarez-Cubero]]'''


</gallery>
</gallery>

Latest revision as of 15:58, 15 February 2024

                



Oroboros Laboratory

Mitochondria and Cell Research - the Oroboros Ecosystem
Scientists with a gentle touch of entrepreneurship
Oroboros Laboratory



Oroboros O2k-Laboratory

42 O2k-Chambers (21 O2k)
The Oroboros O2k-Laboratory ('Mitochondriales Forschungslabor') is a scientific research laboratory in Innsbruck, Austria, and likely the best equipped lab for high-resolution respirometry (HRR) worldwide. The O2k-Lab was opened during the course of the K-Regio project MitoCom Tyrol in June 2013. It comprises 140 sqm which are divided into the office and research areas.
  • Twenty-one O2k instruments for HRR (42 chambers) equipped with automatic Titration-Injection microPumps and the newest O2k-MultiSensor Modules or the NextGen-O2k configuration are available for research and biomedical applications. The newest instrumental designs are used for rigorous testing of our innovations.
  • Two additional O2ks (4 chambers) are devoted to instrumental development.
  • According to the concept of open innovation, the Oroboros O2k-Laboratory welcomes visiting researchers from all over the world.
» More details: Oroboros Support


Joint projects

Functional Mitochondrial Diagnostics (VASCage)
ALAS
TissueModels
MitoKIN
CureMILS


OXPHOS analysis

SUIT protocols are applied in tissue samples from animal models and human patients. Using cultured cells or cells extracted from blood samples, the effects of genotypic variations or of various drugs are studied on OXPHOS parameters, using
  • coupling control protocols (CCP) in intact cells to evaluate effects on ROUTINE respiration, biochemical coupling efficiency and extracellular ROS production under physiological conditions;
  • various substrate-uncoupler-inhibitor titration (SUIT) protocols in permeabilized cells for deep OXPHOS phenotyping (cell ergometry).


» Current projects
» Partners in the Oroboros Ecosystem
» Visiting scientists

Keywords


Questions.jpg


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