Difference between revisions of "Oroboros Laboratory"

Revision as of 10:35, 13 July 2022

Oroboros Laboratory

Mitochondria and Cell Research - the Oroboros Ecosystem

Scientists with a gentle touch of entrepreneurship

Oroboros O2k-Laboratory

40 O2k-Chambers (20 O2k)

The Oroboros O2k-Laboratory ('Mitochondriales Forschungslabor') is a scientific research laboratory in Innsbruck, Austria, and likely the best equipped lab for high-resolution respirometry (HRR) worldwide. The O2k-Lab was opened during the course of the K-Regio project MitoCom Tyrol in June 2013. It comprises 140 sqm which are divided into the office and research areas.

Twenty O2k instruments for HRR (40 chambers) equipped with automatic Titration-Injection microPumps and the newest O2k-MultiSensor Modules or the NextGen-O2k configuration are available for research and biomedical applications. The newest instrumental designs are used for rigorous testing of our innovations.

Two additional O2ks (4 chambers) are devoted to instrumental development.

According to the concept of open innovation, the Oroboros O2k-Laboratory welcomes visiting researchers from all over the world.

» More details: Oroboros Support

Collaborators in the Oroboros Ecosystem

Collaborations

Christine Fischer, MSc., PhD. student
Lisa Bergmeister, PhD. student - SPIN
Omar Torres-Quesada, PhD, PostDoc - MitoKIN

OXPHOS analysis

SUIT protocols are applied in tissue samples from animal models and human patients. Using cultured cells or cells extracted from blood samples, the effects of genotypic variations or of various drugs are studied on OXPHOS parameters, using

coupling control protocols (CCP) in intact cells to evaluate effects on ROUTINE respiration, biochemical coupling efficiency and extracellular ROS production under physiological conditions;
various substrate-uncoupler-inhibitor titration (SUIT) protocols in permeabilized cells for deep OXPHOS phenotyping (cell ergometry).

» Current projects

» Partners in the Oroboros Ecosystem

» Visiting scientists

Keywords

Bioblast links: Oroboros Laboratory - >>>>>>> - Click on [Expand] or [Collapse] - >>>>>>>

» Oroboros Laboratory

» Projects

» Oroboros Laboratory: visiting scientists

» O2k-Open Support by Oroboros experts

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 |}
-== The DSL-Oroboros Research Laboratory ==
-:::: '''8 O2k-Chambers (4 O2k)'''
-:::: {{Template:Oroboros Ecosystem Partner}}
-:::: The '''DSL-Oroboros Research Laboratory''' at the Daniel Swarovski Research Laboratory (DSL), Department of Visceral, Transplant and Thoracic Surgery, Medical University Innsbruck is equipped by Oroboros Instruments with four O2k-FluoRespirometers (8 chambers), particularly devoted to mitochondrial research on human biopsies, cells isolated from blood samples, and cultured cells.
-:::: '''Oroboros Instruments''' collaborates closely with research labs of the Medical University of Innsbruck, the Ludwig-Franzens University of Innsbruck, and with visiting scientists from numerous international research institutions.
-=== Bioenergetics Adventurers in the DSL-Oroboros Research Laboratory ===
-{| style="color: black;  width: 90%"
-|-
-| style="text-align: center;  background-color: #ffffff" | '''[[Oroboros Laboratories |DSL-Oroboros Research Laboratory]]'''
-'''Medical University of Innsbruck'''
-| style="text-align: center;  background-color: #EFF5FB" | <gallery heights="165px" mode="nolines" perrow="6" widths="192px">
-Image:MeszarosA.JPG|'''[[Meszaros A|András Mészáros]]''', MD., PhD.<br/> - Mitochondrial Medicine Visionary
-Image:MittelbergerC.JPG|'''[[Mittelberger C| Christa Mittelberger]]'''<br/> Student
-Image:UnterwegerJ.JPG|'''[[Unterweger J| Jasmin Unterweger]]'''<br/> Student
-Image:ReyerB.JPG|'''[[Reyer BA| Beatrix Ann Reyer]]'''<br/> Student
-Image:HofmannJ.jpg|'''[[Hofmann J| Julia Hofmann, MSc]]'''<br/> PhD student
-File:Van Appeldorn P.jpg|'''[[Van Appeldorn Paula]]''' <br/> Student
-File:Hoelzl K.jpg|'''[[Hoelzl Katharina]]''' <br/> Student
-File:RehseN.jpg|'''[[Rehse Nikolas]]''' <br/> Student
-Image:Profile-icon-9.png|'''[[Buch M| Madita Buch]]'''<br/> Student
-Image:Profile-icon-9.png|'''[[Schipplick F| Florian Schipplick]]'''<br/> Student
-Image:Profile-icon-9.png|'''[[Nardin F| Florian Nardin]]'''<br/> PhD Student
-Image:Profile-icon-9.png|'''[[Sonnberger Lorenz| Lorenz Sonnberger]]'''<br/> Student
-</gallery>
-|}
 == OXPHOS analysis ==