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Description O2k versus multiwell respirometer: O2k stands for Oxygraph-2k and high-resolution respirometry, meeting powerful quality criteria securing high output and pioneering state-of-the-art comprehensive OXPHOS analysis of substrate control and coupling control of mitochondrial function. 'High throughput' stands for disposable multiwell systems - expensive, with limited scope and extremely high running costs. In respirometry, high throughput is not equivalent to high output.
Product ID
Type O2k, Feedback
Link Bioblast pdf

Publications in the MiPMap
O2k and O2k-MultiSensor system: specifications for respirometry and comprehensive OXPHOS analysis. »Bioblast pdf«

» Versions

OROBOROS (2015-05-21) MiPNet

Abstract: Gnaiger E, Fasching M (2015) O2k and O2k-MultiSensor system: specifications for respirometry and comprehensive OXPHOS analysis. Mitochondr Physiol Network 18.10(05): 1-8. Keywords: O2k-Specifications

O2k-Network Lab: AT Innsbruck OROBOROS

Labels: MiParea: Respiration, Instruments;methods 

Organism: Human 

Preparation: Intact cells, Permeabilized cells, Permeabilized tissue, Homogenate, Isolated mitochondria, SMP 

HRR: Oxygraph-2k, TIP2k, O2k-Fluorometer, pH, NO, TPP, Ca, Theory 


Scientists who have experience with both instruments are invited to extend the discussion:

» Tony Hickey: Calibration is my chief concern
» .. and more: Talk:O2k versus multiwell respirometer
» XFe for isolated mitochondria - a critical discussion

Selected related links

» Low running costs for the OROBOROS O2k
» Power-O2k
» O2k-Publications: Topics
» More details on O2k-Specifications? Consult OROBOROS

Conflict of interest

Erich Gnaiger is founder and CEO of OROBOROS INSTRUMENTS, and responsible for the development of the O2k in collaboration with the O2k-Team and our partners. A series of methodological publications is the result of positive feedback between his work as faculty staff of the Medical University of Innsbruck, his company initiatives and numerous international cooperations.

Selected references