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O2k-Publications: Liver

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O2k-Publications: Liver

O2k-Publications in the MiPMap

»O2k-Publications: Topics

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 Was published in yearReferenceOrganismTissue;cell
Ravasz 2024 Sci Rep2024Ravasz D, Bui D, Nazarian S, Pallag G, Karnok N, Roberts J, Marzullo BP, Tennant DA, Greenwood B, Kitayev A, Hill C, KomlĂłdi T, Doerrier C, Cunatova K, Fernandez-Vizarra E, Gnaiger E, Kiebish Michael A, Raska A, Kolev K, Czumbel B, Narain NR, Seyfried TN, Chinopoulos C (2024) Residual Complex I activity and amphidirectional Complex II operation support glutamate catabolism through mtSLP in anoxia. Sci Rep 14:1729. https://doi.org/10.1038/s41598-024-51365-4MouseHeart
Liver
Meszaros 2024 Transpl Int2024Meszaros AT, Weissenbacher A, Schartner M, Egelseer-Bruendl T, Hermann M, Unterweger J, Mittelberger C, Reyer BA, Hofmann J, Zelger BG, Hautz T, Resch T, Margreiter C, Maglione M, Komlódi T, Ulmer H, Cardini B, Troppmair J, Öfner D, Gnaiger E, Schneeberger S, Oberhuber R (2024) The predictive value of graft viability and bioenergetics testing towards the outcome in liver transplantation. Transpl Int 37. https://doi.org/10.3389/ti.2024.12380HumanLiver
Tsouka 2024 Commun Med (Lond)2024Tsouka S, Kumar P, Seubnooch P, Freiburghaus K, St-Pierre M, Dufour JF, Masoodi M (2024) Transcriptomics-driven metabolic pathway analysis reveals similar alterations in lipid metabolism in mouse MASH model and human. Commun Med (Lond) 4:39. https://doi.org/10.1038/s43856-024-00465-3MouseLiver
Dong 2024 Nat Commun2024Dong J, Chen L, Ye F, Tang J, Liu B, Lin J, Zhou PH, Lu B, Wu M, Lu JH, He JJ, Engelender S, Meng Q, Song Z, He H (2024) Mic19 depletion impairs endoplasmic reticulum-mitochondrial contacts and mitochondrial lipid metabolism and triggers liver disease. https://doi.org/10.1038/s41467-023-44057-6MouseLiver
Abegg 2024 Toxicol Lett2024Abegg VF, Panajatovic MV, Mancuso RV, Allard JA, Duthaler U, Odermatt A, KrĂ€henbĂŒhl S, Bouitbir J (2024) Mechanisms of hepatocellular toxicity associated with the components of St. John's Wort extract hypericin and hyperforin in HepG2 and HepaRG cells. https://doi.org/10.1016/j.toxlet.2024.01.008HumanLiver
Balmaceda 2024 Biochim Biophys Acta Mol Basis Dis2024Balmaceda V, Komlodi T, Szibor M, Gnaiger E, Moore AL, Fernandez-Vizarra E, Viscomi C (2024) The striking differences in the bioenergetics of brain and liver mitochondria are enhanced in mitochondrial disease. Biochim Biophys Acta Mol Basis Dis 1870:167033. https://doi.org/10.1016/j.bbadis.2024.167033MouseNervous system
Liver
Mills 2023 Nature2023Mills EL, Ryan DG, Prag HA, Dikovskaya D, Menon D, Zaslona Z, Jedrychowski MP, Costa ASH, Higgins M, Hams E, Szpyt J, Runtsch MC, King MS, McGouran JF, Fischer R, Kessler BM, McGettrick AF, Hughes MM, Carroll RG, Booty LM, Knatko EV, Meakin PJ, Ashford MLJ, Modis LK, Brunori G, SĂ©vin DC, Fallon PG, Caldwell ST, Kunji ERS, Chouchani ET, Frezza C, Dinkova-Kostova AT, Hartley RC, Murphy MP, O'Neill LA (2023) Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. https://doi.org/10.1038/nature25986RatLiver
Yang 2023 Redox Biol2023Yang X, Gu C, Cai J, Li F, He X, Luo L, Xiao W, Hu B, Hu J, Qian H, Ren S, Zhang L, Zhu X, Yang L, Yang J, Yang Z, Zheng Y, Huang X, Wang Z (2023) Excessive SOX8 reprograms energy and iron metabolism to prime hepatocellular carcinoma for ferroptosis. https://doi.org/10.1016/j.redox.2023.103002HumanLiver
Pereyra 2023 Am J Physiol Gastrointest Liver Physiol2023Pereyra AS, McLaughlin KL, Buddo KA, Ellis JM (2023) Medium-chain fatty acid oxidation is independent of L-carnitine in liver and kidney but not in heart and skeletal muscle. https://doi.org/10.1152/ajpgi.00105.2023MouseHeart
Skeletal muscle
Liver
Kidney
Hosler 2023 Mitochondrion2023Hosler J, Hoang N, Shirey Edwards K (2023) The cyclic lipopeptide micafungin induces rupture of isolated mitochondria by reprograming the mitochondrial inner membrane anion channel. https://doi.org/10.1016/j.mito.2023.05.004RatLiver
Salmon 2023 Geroscience2023SalmĂłn P, Millet C, Selman C, Monaghan P, Dawson NJ (2023) Tissue-specific reductions in mitochondrial efficiency and increased ROS release rates during ageing in zebra finches, Taeniopygia guttata. https://doi.org/10.1007/s11357-022-00624-1BirdsSkeletal muscle
Liver
Chen 2023 Nat Commun2023Chen M, Zhu JY, Mu WJ, Luo HY, Li Y, Li S, Yan LJ, Li RY, Guo L (2023) Cdo1-Camkk2-AMPK axis confers the protective effects of exercise against NAFLD in mice. https://doi.org/10.1038/s41467-023-44242-7HumanLiver
Clemente 2023 Commun Biol2023Clemente N, Baroni S, Fiorilla S, Tasso F, Reano S, Borsotti C, Ruggiero MR, Alchera E, Corrazzari M, Walker G, Follenzi A, Crich SG, Carini R (2023) Boosting intracellular sodium selectively kills hepatocarcinoma cells and induces hepatocellular carcinoma tumor shrinkage in mice. https://doi.org/10.1038/s42003-023-04946-4HumanLiver
Horcas-Nieto 2023 Biochim Biophys Acta Mol Basis Dis2023Horcas-Nieto JM, Versloot CJ, Langelaar-Makkinje M, Gerding A, Blokzijl T, Koster MH, Baanstra M, Martini IA, Coppes RP, Bourdon C, van Ijzendoorn SCD, Kim P, Bandsma RHJ, Bakker BM (2023) Organoids as a model to study intestinal and liver dysfunction in severe malnutrition. https://doi.org/10.1016/j.bbadis.2022.166635MouseLiver
Other cell lines
Vilas-Boas 2023 J Biol Chem2023Vilas-Boas EA, Cabral-Costa JV, Ramos VM, Caldeira da Silva CC, Kowaltowski AJ (2023) Goldilocks calcium concentrations and the regulation of oxidative phosphorylation: too much, too little, or just right. https://doi.org/10.1016/j.jbc.2023.102904MouseLiver
Garcia-Roche 2023 PLoS One2023García-Roche M, Talmón D, Cañibe G, Astessiano AL, Mendoza A, Cassina A, Quijano C, Carriquiry M (2023) Hepatic metabolism of grazing cows of two Holstein strains under two feeding strategies with different levels of pasture inclusion. https://doi.org/10.1371/journal.pone.0290551BovinesLiver
Horvath 2023 Antioxidants (Basel)2023Horvåth T, Såndor L, Baråth B, Donka T, Baråth B, Mohåcsi Á, Jåsz KD, Hartmann P, Boros M (2023) Methane admixture protects liver mitochondria and improves graft function after static cold storage and reperfusion. Antioxidants (Basel) 12:271. https://doi.org/10.3390/antiox12020271RatLiver
Jiang 2023 Sci Rep2023Jiang N, Wang Z, Guo X, Peng Z, He Y, Wang Q, Wu H, Cui Y (2023) Hepatic Runx1t1 improves body fat index after endurance exercise in obese mice. https://doi.org/10.1038/s41598-023-46302-wMouseLiver
Peixoto 2023 J Physiol Biochem2023Peixoto ÁS, Moreno MF, Castro É, Perandini LA, Belchior T, Oliveira TE, Vieira TS, Gilio GR, Tomazelli CA, Leonardi BF, Ortiz-Silva M, Silva Junior LP, Moretti EH, Steiner AA, Festuccia WT (2023) Hepatocellular carcinoma induced by hepatocyte Pten deletion reduces BAT UCP-1 and thermogenic capacity in mice, despite increasing serum FGF-21 and iWAT browning. https://doi.org/10.1007/s13105-023-00970-4MouseLiver
Fat
Duran-Gueell 2023 FASEB J2023Duran-GĂŒell M, Garrabou G, Flores-Costa R, Casulleras M, LĂłpez-Vicario C, Zhang IW, CantĂł-Santos J, Contreras BJ, SĂĄnchez-RodrĂ­guez MB, Romero-Grimaldo B, Horrillo R, Costa M, Arroyo V, ClĂ ria J (2023) Essential role for albumin in preserving liver cells from TNFα-induced mitochondrial injury. https://doi.org/10.1096/fj.202201526rMouseLiver
Zhang 2023 Nat Commun2023Zhang Y, Fan Y, Hu H, Zhang X, Wang Z, Wu Z, Wang L, Yu X, Song X, Xiang P, Zhang X, Wang T, Tan S, Li C, Gao L, Liang X, Li S, Li N, Yue X, Ma C (2023) ZHX2 emerges as a negative regulator of mitochondrial oxidative phosphorylation during acute liver injury. https://doi.org/10.1038/s41467-023-43439-0MouseLiver
Dewidar 2023 EBioMedicine2023Dewidar B, Mastrototaro L, Englisch C, Ress C, Granata C, Rohbeck E, Pesta D, Heilmann G, Wolkersdorfer M, Esposito I, Reina Do Fundo M, Zivehe F, Yavas A, Roden M (2023) Alterations of hepatic energy metabolism in murine models of obesity, diabetes and fatty liver diseases. https://doi.org/10.1016/j.ebiom.2023.104714MouseSkeletal muscle
Liver
Belosludtseva 2022 Membranes (Basel)2022Belosludtseva NV, Pavlik LL, Belosludtsev KN, Saris NL, Shigaeva MI, Mironova GD (2022) The short-term opening of cyclosporin A-independent palmitate/Sr 2+-induced pore can underlie ion efflux in the oscillatory mode of functioning of rat liver mitochondria. https://doi.org/10.3390/membranes12070667RatLiver
Beaulant 2022 J Hepatol2022Beaulant A, Dia M, Pillot B, Chauvin MA, Ji-Cao J, Durand C, Bendridi N, Chanon S, Vieille-Marchiset A, Da Silva CC, Patouraux S, Anty R, Iannelli A, Tran A, Gual P, Vidal H, Gomez L, Paillard M, Rieusset J (2022) Endoplasmic reticulum-mitochondria miscommunication is an early and causal trigger of hepatic insulin resistance and steatosis. https://doi.org/10.1016/j.jhep.2022.03.017MouseLiver
Fischer 2022 Metabolites2022Fischer C, Valente de Souza L, KomlĂłdi T, Garcia-Souza LF, Volani C, Tymoszuk P, Demetz E, Seifert M, Auer K, Hilbe R, Brigo N, Petzer V, Asshoff M, Gnaiger E, Weiss G (2022) Mitochondrial respiration in response to iron deficiency anemia. Comparison of peripheral blood mononuclear cells and liver. https://doi.org/10.3390/metabo12030270RatLiver
Blood cells
Pedersen 2022 Nat Commun2022Pedersen JS, Rygg MO, ChrĂžis K, Sustarsic EG, Gerhart-Hines Z, Wever Albrechtsen NJ, Serizawa RR, Kristiansen VB, Basse AL, Boilesen AEB, Olsen BH, Hansen T, Gluud LL, Madsbad S, Larsen S, Bendtsen F, Dela F (2022) Influence of NAFLD and bariatric surgery on hepatic and adipose tissue mitochondrial biogenesis and respiration. https://doi.org/10.1038/s41467-022-30629-5HumanLiver
Fat
Meszaros 2022 EBioMedicine2022Meszaros AT, Hofmann J, Buch ML, Cardini B, Dunzendorfer-Matt T, Nardin F, Blumer MJ, Fodor M, Hermann M, Zelger B, Otarashvili G, Schartner M, Weissenbacher A, Oberhuber R, Resch T, Troppmair J, Öfner D, Zoller H, Tilg H, Gnaiger E, Hautz T, Schneeberger S (2022) Mitochondrial respiration during normothermic liver machine perfusion predicts clinical outcome. https://doi.org/10.1016/j.ebiom.2022.104311HumanLiver
Ilha 2022 Cell Biol Int2022Ilha M, Meira Martins LA, da Silveira Moraes K, Dias CK, Thomé MP, Petry F, Rohden F, Borojevic R, Trindade VMT, Klamt F, Barbé-Tuana F, Lenz G, Guma FCR (2022) Caveolin-1 influences mitochondrial plasticity and function in hepatic stellate cell activation. https://doi.org/10.1002/cbin.11876MouseLiver
Mihajlovic 2022 Int J Mol Sci2022Mihajlovic M, Vinken M (2022) Mitochondria as the target of hepatotoxicity and drug-induced liver injury: molecular mechanisms and detection methods. https://doi.org/10.3390/ijms23063315Liver
Serna 2022 MitoFit2022Serna JDC, Ramos VM, Cabral-Costa JV, Vilas-Boas EA, Amaral AG, Ohya G, da Silva CCC, Kowaltowski AJ (2022) Measuring mitochondrial Ca2+ efflux in isolated mitochondria and permeabilized cells. https://doi.org/10.26124/mitofit:2022-0021 — 2022-07-28 published in Bioenerg Commun 2022.7.Human
Mouse
Liver
Other cell lines
Desjardins 2022 Proc Natl Acad Sci U S A2022Desjardins EM, Smith BK, Day EA, Ducommun S, Sanders MJ, Nederveen JP, Ford RJ, Pinkosky SL, Townsend LK, Gutgesell RM, Lu R, Sakamoto K, Steinberg GR (2022) The phosphorylation of AMPKÎČ1 is critical for increasing autophagy and maintaining mitochondrial homeostasis in response to fatty acids. https://doi.org/10.1073/pnas.2119824119MouseLiver
Felix 2022 Chemosphere2022FĂ©lix L, Carreira P, Peixoto F (2022) Effects of chronic exposure of naturally weathered microplastics on oxidative stress level, behaviour, and mitochondrial function of adult zebrafish (Danio rerio). https://doi.org/10.1016/j.chemosphere.2022.136895ZebrafishNervous system
Liver
Jelenik 2022 Pharmacol Res2022Jelenik T, Kodde A, Pesta D, Phielix E, Oosting A, Rohbeck E, Dewidar B, Mastrototaro L, Trenkamp S, Keijer J, van der Beek EM, Roden M (2022) Dietary lipid droplet structure in postnatal life improves hepatic energy and lipid metabolism in a mouse model for postnatal programming. https://doi.org/10.1016/j.phrs.2022.106193MouseSkeletal muscle
Liver
Gomez 2022 Nutrients2022GĂłmez RodrĂ­guez A, Talamonti E, Naudi A, Kalinovich AV, Pauter AM, Barja G, Bengtsson T, Jacobsson A, Pamplona R, Shabalina IG (2022) Elovl2-ablation leads to mitochondrial membrane fatty acid remodeling and reduced efficiency in mouse liver mitochondria. https://doi.org/10.3390/nu14030559MouseLiver
Pallag 2022 Int J Mol Sci2022Pallag G, Nazarian S, Ravasz D, Bui D, KomlĂłdi T, Doerrier C, Gnaiger E, Seyfried TN, Chinopoulos C (2022) Proline oxidation supports mitochondrial ATP production when Complex I is inhibited. https://doi.org/10.3390/ijms23095111MouseLiver
Kidney
Garcia-Roche 2022 J Dairy Sci2022García-Roche M, Talmón D, Cañibe G, Astessiano AL, Mendoza A, Quijano C, Cassina A, Carriquiry M (2022) Differential hepatic mitochondrial function and gluconeogenic gene expression in 2 Holstein strains in a pasture-based system. https://doi.org/10.3168/jds.2021-21358BovinesLiver
Fuertes-Agudo 2022 Antioxidants (Basel)2022Fuertes-Agudo M, Luque-TĂ©var M, Cucarella C, Brea R, BoscĂĄ L, Quintana-Cabrera R, MartĂ­n-Sanz P, Casado M (2022) COX-2 expression in hepatocytes improves mitochondrial function after hepatic ischemia-reperfusion injury.MouseLiver
Daradics 2022 PLoS One2022Daradics N, Horvath G, Tretter L, Paal A, Fulop A, Budai A, Szijarto A (2022) The effect of Cyclophilin D depletion on liver regeneration following associating liver partition and portal vein ligation for staged hepatectomy. https://doi.org/10.1371/journal.pone.0271606MouseLiver
Rome 2022 Mol Metab2022Rome FI, Hughey CC (2022) Disrupted liver oxidative metabolism in glycine N-methyltransferase-deficient mice is mitigated by dietary methionine restriction. https://doi.org/10.1016/j.molmet.2022.101452MouseLiver
Siow 2022 J Cell Sci2022Siow WX, Kabiri Y, Tang R, Chao YK, Plesch E, Eberhagen C, Flenkenthaler F, Fröhlich T, Bracher F, Grimm C, Biel M, Zischka H, Vollmar AM, Bartel K (2022) Lysosomal TRPML1 regulates mitochondrial function in hepatocellular carcinoma cells. https://doi.org/10.1242/jcs.259455MouseLiver
Gancheva 2022 Diabetes Care2022Gancheva S, Kahl S, Pesta D, Mastrototaro L, Dewidar B, Strassburger K, Sabah E, Esposito I, Weiß J, Sarabhai T, Wolkersdorfer M, Fleming T, Nawroth P, Zimmermann M, Reichert AS, Schlensak M, Roden M (2022) Impaired hepatic mitochondrial capacity in nonalcoholic steatohepatitis associated with type 2 diabetes. https://doi.org/10.2337/dc21-1758Liver
Melin 2022 JHEP Rep2022Melin N, Yarahmadov T, Sanchez-Taltavull D, Birrer FE, Brodie TM, Petit B, Felser A, Nuoffer JM, Montani M, Vozenin MC, Herrmann E, Candinas D, Aebersold DM, Stroka D (2022) A new mouse model of radiation-induced liver disease reveals mitochondrial dysfunction as an underlying fibrotic stimulus. https://doi.org/10.1016/j.jhepr.2022.100508MouseLiver
Pallag 2022 MitoFit Proline2022Pallag G, Nazarian S, Ravasz D, Bui D, Komlódi T, Doerrier C, Gnaiger E, Seyfried TN, Chinopoulos C (2022) Proline oxidation leading to high electron flow through reduction of ubiquinone supports ATP production by F1FO-ATPase in mitochondria with inhibited Complex I. https://doi.org/10.26124/mitofit:2022-0001.v3 — 2022-05-04 published in https://doi.org/10.3390/ijms23095111MouseHeart
Kidney
Liver
Nervous system
Roy 2022 Am J Pathol2022Roy N, Alencastro F, Roseman BA, Wilson SR, Delgado ER, May MC, Bhushan B, Bello FM, Jurczak MJ, Shiva S, Locker J, Gingras S, Duncan AW (2022) Dysregulation of lipid and glucose homeostasis in hepatocyte-specific SLC25A34 knockout mice. https://doi.org/10.1016/j.ajpath.2022.06.002MouseLiver
Jedlicka 2022a Physiol Res2022Jedlička J, TĆŻma Z, Razak K, Kunc R, Kala A, Proskauer Pena S, Lerchner T, JeĆŸek K, KuncovĂĄ J (2022) Impact of aging on mitochondrial respiration in various organs. https://doi.org/10.33549/physiolres.934995RatHeart
Skeletal muscle
Nervous system
Liver
Kidney
Platelet
Gonzalez-Franquesa 2022 Redox Biol2022Gonzalez-Franquesa A, Gama-Perez P, Kulis M, Szczepanowska K, Dahdah N, Moreno-Gomez S, Latorre-Pellicer A, FernĂĄndez-Ruiz R, Aguilar-Mogas A, Hoffman A, Monelli E, Samino S, MirĂł-Blanch J, Oemer G, Duran X, Sanchez-Rebordelo E, Schneeberger M, Obach M, Montane J, Castellano G, Chapaprieta V, Sun W, Navarro L, Prieto I, Castaño C, Novials A, Gomis R, Monsalve M, Claret M, Graupera M, Soria G, Wolfrum C, Vendrell J, FernĂĄndez-Veledo S, EnrĂ­quez JA, Carracedo A, Perales JC, Nogueiras R, Herrero L, Trifunovic A, Keller MA, Yanes O, Sales-Pardo M, GuimerĂ  R, BlĂŒher M, MartĂ­n-Subero JI, Garcia-Roves PM (2022) Remission of obesity and insulin resistance is not sufficient to restore mitochondrial homeostasis in visceral adipose tissue. https://doi.org/10.1016/j.redox.2022.102353MouseSkeletal muscle
Nervous system
Liver
Fat
Markovic 2022 Biomedicines2022Marković A, TauchmannovĂĄ K, Ć imĂĄkovĂĄ M, Mlejnek P, KaplanovĂĄ V, Pecina P, PecinovĂĄ A, PapouĆĄek F, LiĆĄka F, Ć ilhavĂœ J, MikeĆĄovĂĄ J, Neckáƙ J, HouĆĄtěk J, Pravenec M, Mráček T (2022) Genetic complementation of ATP synthase deficiency due to dysfunction of TMEM70 assembly factor in rat. https://doi.org/10.3390/biomedicines10020276RatHeart
Liver
Serna 2022 BEC2022Serna JDC, Ramos VM, Cabral-Costa JV, Vilas-Boas EA, Amaral AG, Ohya G, da Silva CCC, Kowaltowski AJ (2022) Measuring mitochondrial Ca2+ efflux in isolated mitochondria and permeabilized cells. Bioenerg Commun 2022.7. https://doi.org/10.26124/bec:2022-0007Human
Mouse
Liver
Other cell lines
Hansen 2022 Magn Reson Med2022Hansen K, Hansen ESS, Jespersen NRV, BĂžtker HE, Pedersen M, Wang T, Laustsen C (2022) Hyperpolarized 13C MRI reveals large changes in pyruvate metabolism during digestion in snakes. https://doi.org/10.1002/mrm.29239ReptilesLiver
Barath 2022 Int J Mol Sci2022Baråth B, Jåsz DK, Horvåth T, Baråth B, Maróti G, Strifler G, Varga G, Såndor L, Perényi D, Tallósy S, Donka T, Jåvor P, Boros M, Hartmann P (2022) Mitochondrial side effects of surgical prophylactic antibiotics Ceftriaxone and Rifaximin lead to bowel mucosal damage. Int J Mol Sci 23:5064. https://doi.org/10.3390/ijms23095064RatLiver
Molinie 2022 Biochim Biophys Acta Bioenerg2022Molinié T, Cougouilles E, David C, Cahoreau E, Portais JC, Mourier A (2022) MDH2 produced OAA is a metabolic switch rewiring the fuelling of respiratory chain and TCA cycle. Biochim Biophys Acta Bioenerg 1863:148532.MouseHeart
Liver
Bresciani 2022 J Hepatol2022Bresciani N, Demagny H, Lemos V, Pontanari F, Li X, Sun Y, Li H, Perino A, Auwerx J, Schoonjans K (2022) The Slc25a47 locus is a novel determinant of hepatic mitochondrial function implicated in liver fibrosis. https://doi.org/10.1016/j.jhep.2022.05.040MouseLiver
Zhu 2022 Metabolism2022Zhu JY, Chen M, Mu WJ, Luo HY, Guo L (2022) Higd1a facilitates exercise-mediated alleviation of fatty liver in diet-induced obese mice. https://doi.org/10.1016/j.metabol.2022.155241MouseLiver
Fink 2021 Pharmacol Res Perspect2021Fink BD, Yu L, Coppey L, Obrosov A, Shevalye H, Kerns RJ, Yorek MA, Sivitz WI (2021) Effect of mitoquinone on liver metabolism and steatosis in obese and diabetic rats. Pharmacol Res Perspect 9:e00701.RatLiver
Mazzoli 2021 Nutrients2021Mazzoli A, Gatto C, Crescenzo R, Cigliano L, Iossa S (2021) Prolonged changes in hepatic mitochondrial activity and insulin sensitivity by high fructose intake in adolescent rats. Nutrients 13:1370.RatLiver
Stankova 2021 Int J Mol Sci2021Staƈková P, Kučera O, Peterová E, Elkalaf M, Rychtrmoc D, Melek J, Podhola M, Zubáƈová V, Červinková Z (2021) Western diet decreases the liver mitochondrial oxidative flux of succinate: insight from a murine NAFLD model. https://doi.org/10.3390/ijms22136908MouseLiver
Dos Santos Escaliante 2021 Int J Biol Macromol2021Dos Santos Escaliante LA, Busato B, de Oliveira Petkowicz CL, Suter Correia Cadena SM, Rodrigues Noleto G (2021) Cytotoxic effect of xyloglucan and oxovanadium (IV/V) xyloglucan complex in HepG2 cells. Int J Biol Macromol 185:40-48.HumanLiver
Dall 2021 J Biol Chem2021Dall M, Hassing AS, Niu L, Nielsen TS, Ingerslev LR, Sulek K, Trammell SAJ, Gillum MP, BarrÚs R, Larsen S, Poulsen SS, Mann M, Ørskov C, Treebak JT (2021) Hepatocyte-specific perturbation of NAD+ biosynthetic pathways in mice induces reversible nonalcoholic steatohepatitis-like phenotypes. J Biol Chem 297:101388.MouseLiver
Hwang 2021 Crit Care2021Hwang JW, Lee MJ, Chung TN, Lee HAR, Lee JH, Choi SY, Park YJ, Kim CH, Jin I, Kim SH, Kwak HB, Heo JW, Na K, Choi S, Choi YS, Kim K (2021) The immune modulatory effects of mitochondrial transplantation on cecal slurry model in rat. Crit Care 25:20.RatSkeletal muscle
Liver
Kidney
Blood cells
Dubinin 2021 Free Radic Biol Med2021Dubinin MV, Semenova AA, Ilzorkina AI, Penkov NV, Nedopekina DA, Sharapov VA, Khoroshavina EI, Davletshin EV, Belosludtseva NV, Spivak AY, Belosludtsev KN (2021) Mitochondria-targeted prooxidant effects of betulinic acid conjugated with delocalized lipophilic cation F16. Free Radic Biol Med 168:55-69.RatLiver
Fischer 2021 Antioxidants2021Fischer C, Volani C, KomlĂłdi T, Seifert M, Demetz E, Valente de Souza L, Auer K, Petzer V, von Raffay L, Moser P, Gnaiger E, Weiss G (2021) Dietary iron overload and Hfe-/- related hemochromatosis alter hepatic mitochondrial function. https://doi.org/10.3390/antiox10111818MouseLiver
Mukherjee 2021 JCI Insight2021Mukherjee S, Mo J, Paolella LM, Perry CE, Toth J, Hugo MM, Chu Q, Tong Q, Chellappa K, Baur JA (2021) SIRT3 is required for liver regeneration but not for the beneficial effect of nicotinamide riboside. JCI Insight 6:e14719.MouseLiver
Valera-Alberni 2021 Cell Rep2021Valera-Alberni M, Joffraud M, Miro-Blanch J, Capellades J, Junza A, Dayon L, NĂșñez Galindo A, Sanchez-Garcia JL, Valsesia A, Cercillieux A, Söllner F, Ladurner AG, Yanes O, CantĂł C (2021) Crosstalk between Drp1 phosphorylation sites during mitochondrial remodeling and their impact on metabolic adaptation. Cell Rep 36:109565.MouseLiver
Fat
Moon 2021 J Lipid Res2021Moon SH, Dilthey BG, Liu X, Guan S, Sims HF, Gross RW (2021) High-Fat diet activates liver iPLA2Îł generating eicosanoids that mediate metabolic stress. J Lipid Res 62:100052.MouseLiver
Schmidt 2021 Cancer Metab2021Schmidt CA, McLaughlin KL, Boykov IN, Mojalagbe R, Ranganathan A, Buddo KA, Lin CT, Fisher-Wellman KH, Neufer PD (2021) Aglycemic growth enhances carbohydrate metabolism and induces sensitivity to menadione in cultured tumor-derived cells. Cancer Metab 9:3.HumanLiver
Jensen 2021 Free Radic Biol Med2021Jensen BS, Pardue S, Duffy B, Kevil CG, Staples JF, Fago A (2021) Suppression of mitochondrial respiration by hydrogen sulfide in hibernating 13-lined ground squirrels. Free Radic Biol Med 169:181-86.Other mammalsLiver
Tallosy 2021 Sci Rep2021TallĂłsy SP, Poles MZ, Rutai A, Fejes R, JuhĂĄsz L, BuriĂĄn K, SĂłki J, SzabĂł A, Boros M, Kaszaki J (2021) The microbial composition of the initial insult can predict the prognosis of experimental sepsis. Sci Rep 11:22772.RatLiver
Deline 2021 Biochim Biophys Acta Bioenerg2021Deline ML, Grashei M, van Heijster FHA, Schilling F, Straub J, Fromme T (2021) Adenylate kinase derived ATP shapes respiration and calcium storage of isolated mitochondria. Biochim Biophys Acta Bioenerg 1862:148409.MouseLiver
Rossetti 2021 Sci Adv2021Rossetti G, Ermer JA, Stentenbach M, Siira SJ, Richman TR, Milenkovic D, Perks KL, Hughes LA, Jamieson E, Xiafukaiti G, Ward NC, Takahashi S, Gray N, Viola HM, Hool LC, Rackham O, Filipovska A (2021) A common genetic variant of a mitochondrial RNA processing enzyme predisposes to insulin resistance. Sci Adv 7:eabi7514.MouseLiver
Martin 2021 J Exp Biol2021Martin KE, Currie S, Pichaud N (2021) Mitochondrial physiology and responses to elevated hydrogen sulphide in two isogenic lineages of an amphibious mangrove fish. J Exp Biol 224:jeb241216.FishesLiver
Kakimoto 2021 Redox Biol2021Kakimoto PA, Serna JDC, de Miranda Ramos V, Zorzano A, Kowaltowski AJ (2021) Increased glycolysis is an early consequence of palmitate lipotoxicity mediated by redox signaling. Redox Biol 45:102026.HumanLiver
Schumann 2021 Commun Biol2021Schumann T, Koenig J, von Loeffelholz C, Vatner DF, Zhang D, Perry RJ, Bernier M, Chami J, Henke C, Kurzbach A, El-Agroudy NN, Willmes DM, Pesta D, de Cabo R, O Sullivan JF, Simon E, Shulman GI, Hamilton BS, Birkenfeld AL (2021) Deletion of the diabetes candidate gene Slc16a13 in mice attenuates diet-induced ectopic lipid accumulation and insulin resistance. Commun Biol 4:826.MouseLiver
Larsen 2021 Cell Mol Gastroenterol Hepatol2021Larsen LE, van den Boogert MAW, Rios-Ocampo WA, Jansen JC, Conlon D, Chong PLE, Levels JHM, Eilers RE, Sachdev VV, Zelcer N, Raabe T, He M, Hand NJ, Drenth JPH, Rader DJ, Stroes ESG, Lefeber DJ, Jonker JW, Holleboom AG (2021) Defective lipid droplet - lysosome interaction causes fatty liver disease as evidenced by human mutations in TMEM199 and CCDC115. Cell Mol Gastroenterol Hepatol 13:583-97.HumanLiver
Pereyra 2021 J Lipid Res2021Pereyra AS, Harris KL, Soepriatna AH, Waterbury QA, Bharathi SS, Zhang Y, Fisher-Wellman KH, Goergen CJ, Goetzman ES, Ellis JM (2021) Octanoate is differentially metabolized in liver and muscle and fails to rescue cardiomyopathy in CPT2 deficiency. J Lipid Res 62:100069.MouseHeart
Skeletal muscle
Liver
Christiansen 2021 Sci Rep2021Christiansen LB, Dohlmann TL, Ludvigsen TP, Parfieniuk E, Ciborowski M, Szczerbinski L, Kretowski A, Desler C, Tiano L, Orlando P, Martinussen T, Olsen LH, Larsen S (2021) Atorvastatin impairs liver mitochondrial function in obese Göttingen Minipigs but heart and skeletal muscle are not affected. Sci Rep 11:2167.PigHeart
Skeletal muscle
Liver
Dubinin 2021 Membranes (Basel)2021Dubinin MV, Semenova AA, Nedopekina DA, Davletshin EV, Spivak AY, Belosludtsev KN (2021) Effect of F16-betulin conjugate on mitochondrial membranes and its role in cell death initiation. Membranes (Basel) 11:352.RatLiver
Goldberg 2021 Biochem J2021Goldberg EJ, Buddo KA, McLaughlin KL, Fernandez RF, Pereyra AS, Psaltis CE, Lin CT, Hagen JT, Boykov IN, Nguyen TK, Gowdy KM, Ellis JM, Neufer PD, McClung JM, Fisher-Wellman KH (2021) Tissue-specific characterization of mitochondrial branched-chain keto acid oxidation using a multiplexed assay platform. Biochem J 476:1521-37.MouseHeart
Skeletal muscle
Liver
Hoene 2021 Mol Metab2021Hoene M, Kappler L, Kollipara L, Hu C, Irmler M, Bleher D, Hoffmann C, Beckers J, Hrabě de Angelis M, HĂ€ring HU, Birkenfeld AL, Peter A, Sickmann A, Xu G, Lehmann R, Weigert C (2021) Exercise prevents fatty liver by modifying the compensatory response of mitochondrial metabolism to excess substrate availability. Mol Metab 54:101359.MouseLiver
Krako Jakovljevic 2021 Int J Mol Sci2021Krako Jakovljevic N, Pavlovic K, Jotic A, Lalic K, Stoiljkovic M, Lukic L, Milicic T, Macesic M, Stanarcic Gajovic J, Lalic NM (2021) Targeting mitochondria in diabetes. Int J Mol Sci 22:6642.HumanSkeletal muscle
Liver
Blood cells
Vidimce 2021 Front Pharmacol2021Vidimce J, Pillay J, Shrestha N, Dong LF, Neuzil J, Wagner KH, Holland OJ, Bulmer AC (2021) Mitochondrial function, fatty acid metabolism, and body composition in the hyperbilirubinemic gunn rat. Front Pharmacol 12:586715.RatSkeletal muscle
Liver
Zhou 2020 Biomed Pharmacother2020Zhou J, Zhang Y, Li S, Zhou Q, Lu Y, Shi J, Liu J, Wu Q, Zhou S (2020) Dendrobium nobile Lindl. alkaloids-mediated protection against CCl4-induced liver mitochondrial oxidative damage is dependent on the activation of Nrf2 signaling pathway. Biomed Pharmacother 129:110351.MouseLiver
Jian 2020 Cell Metab2020Jian C, Fu J, Cheng X, Shen LJ, Ji YX, Wang X, Pan S, Tian H, Tian S, Liao R, Song K, Wang HP, Zhang X, Wang Y, Huang Z, She ZG, Zhang XJ, Zhu L, Li H (2020) Low-dose sorafenib acts as a mitochondrial uncoupler and ameliorates nonalcoholic steatohepatitis. Cell Metab 31:892-908. https://doi.org/10.1016/j.cmet.2020.04.011MouseLiver
Garcia 2020 Mol Hum Reprod2020Garcia BM, Machado TS, Carvalho KF, Nolasco P, Nociti RP, Del Collado M, Capo Bianco MJD, Grejo MP, Neto JDA, Sugiyama FHC, Tostes K, Pandey AK, Gonçalves LM, Perecin F, Meirelles FV, Ferraz JBS, Vanzela EC, Boschero AC, Guimarães FEG, Abdulkader F, Laurindo FRM, Kowaltowski AJ, Chiaratti MR (2020) Mice born to females with oocyte-specific deletion of mitofusin 2 have increased weight gain and impaired glucose homeostasis. Mol Hum Reprod 26:938-52.MouseLiver
Venediktova 2020 Mitochondrion2020Venediktova NI, Mashchenko OV, Talanov EY, Belosludtseva NV, Mironova GD (2020) Energy metabolism and oxidative status of rat liver mitochondria in conditions of experimentally induced hyperthyroidism. Mitochondrion 52:190-96.RatLiver
Messner 2020 Thesis2020Messner M (2020) Sorafenib resistance of hepatocellular carcinoma. PhD Thesis 130.HumanLiver
Cecatto 2020 Mitochondrion2020Cecatto C, Amaral AU, Wajner A, Wajner SM, Castilho RF, Wajner M (2020) Disturbance of mitochondrial functions associated with permeability transition pore opening induced by cis-5-tetradecenoic and myristic acids in liver of adolescent rats. Mitochondrion 50:1-13.RatLiver
Other cell lines
Belosludtseva 2020 Bull Exp Biol Med2020Belosludtseva NV, Talanov EY, Venediktova NI, Sharapov MG, Mironova GD, Belosludtsev KN (2020) Structural and functional features of Ca2+ transport systems in liver mitochondria of rats with experimental hyperthyroidism. Bull Exp Biol Med 169:224-28.RatLiver
Shi 2020 Diabetes2020Shi JH, Lu JY, Chen HY, Wei CC, Xu X, Li H, Bai Q, Xia FZ, Lam SM, Zhang H, Shi YN, Cao D, Chen L, Shui G, Yang X, Lu Y, Chen YX, Zhang WJ (2020) Liver ChREBP protects against fructose-induced glycogenic hepatotoxicity by regulating L-type pyruvate kinase. Diabetes 120:29.MouseLiver
De Souza 2020 Heliyon2020De Souza CEA, Andrade Pires AR, Cardoso CR, Carlos RM, Cadena SMSC, Acco A (2020) Antineoplastic activity of a novel ruthenium complex against human hepatocellular carcinoma (HepG2) and human cervical adenocarcinoma (HeLa) cells. Heliyon 6:e03862.HumanLiver
HeLa
Song 2020 Life Sci2020Song K, Zhang Y, Ga Q, Bai Z, Ge RL (2020) High-altitude chronic hypoxia ameliorates obesity-induced non-alcoholic fatty liver disease in mice by regulating mitochondrial and AMPK signaling. Life Sci 252:117633.MouseLiver
Lensu 2020 Preprints2020Lensu S, Pariyani R, MĂ€kinen E, Yang B, Saleem W, Munukka E, Lehti M, Driuchina A, Linden J, Tiirola M, Lahti L, Pekkala S (2020) Prebiotic xylo-oligosaccharides targeting Faecalibacterium prausnitzii prevent high fat diet-induced hepatic steatosis in rats. Preprints 2020:2020090241.RatLiver
Hedges 2020 Biosci Rep2020Hedges CP, Pham T, Shetty B, Masson SWC, Hickey AJR, Shepherd PR, Merry TL (2020) Prolonged treatment with a PI3K p110α inhibitor causes sex- and tissue-dependent changes in antioxidant content, but does not affect mitochondrial function. https://doi.org/10.1042/bsr20201128MouseSkeletal muscle
Liver
Ferreira 2020 PLoS Genet2020Ferreira N, Andoniou CE, Perks KL, Ermer JA, Rudler DL, Rossetti G, Periyakaruppiah A, Wong JKY, Rackham O, Noakes PG, Degli-Esposti MA, Filipovska A (2020) Murine cytomegalovirus infection exacerbates complex IV deficiency in a model of mitochondrial disease. PLoS Genet 16:e1008604.MouseLiver
Edmunds 2020 Mol Metab2020Edmunds LR, Xie B, Mills AM, Huckestein BR, Undamatla R, Murali A, Pangburn MM, Martin J, Sipula I, Kaufman BA, Scott I, Jurczak MJ (2020) Liver-specific Prkn knockout mice are more susceptible to diet-induced hepatic steatosis and insulin resistance. Mol Metab 41:101051.MouseLiver
Allen 2020 Thesis2020Allen FM (2020) Mitochondrial metabolism elucidated by rapid fractionation from tissue. PhD Thesis 298.Mouse
Rat
Heart
Liver
Li 2020 Cells2020Li M, Wang L, Wang Y, Zhang S, Zhou G, Lieshout R, Ma B, Liu J, Qu C, Verstegen MMA, Sprengers D, Kwekkeboom J, van der Laan LJW, Cao W, Peppelenbosch MP, Pan Q (2020) Mitochondrial fusion via OPA1 and MFN1 supports liver tumor cell metabolism and growth. Cells 9:E121.HumanLiver
Carvalho 2020 BMC Nutr2020Carvalho E, Adams SH, Borsheim E, Blackburn ML, Ono-Moore KD, Cotter M, Bowlin AK, Yeruva L (2020) Neonatal diet impacts liver mitochondrial bioenergetics in piglets fed formula or human milk. BMC Nutr 6:13.PigLiver
Deleye 2020 J Biol Chem2020Deleye Y, Cotte AK, Hannou SA, Hennuyer N, Bernard L, Derudas B, Caron S, Legry V, Vallez E, Dorchies E, Martin N, Lancel S, Annicotte JS, Bantubungi K, Pourtier A, Raverdy V, Pattou F, Lefebvre P, Abbadie C, Staels B, Haas JT, Paumelle R (2020) CDKN2A/p16INK4a suppresses hepatic fatty acid oxidation through the AMPKα2-SIRT1-PPARα signaling pathway. J Biol Chem 295:17310-22.MouseLiver
Khamoui 2020 Physiol Genomics2020Khamoui AV, Tokmina-Roszyk D, Rossiter HB, Fields GB, Visavadiya NP (2020) Hepatic proteome analysis reveals altered mitochondrial metabolism and suppressed acyl-CoA synthetase-1 in colon-26 tumor-induced cachexia. Physiol Genomics 52:203-16.MouseLiver
Weber 2020 FASEB J2020Weber M, Mera P, Casas J, Salvador J, RodrĂ­guez A, Alonso S, SebastiĂĄn D, Soler-VĂĄzquez MC, Montironi C, Recalde S, Fucho R, CalderĂłn-DomĂ­nguez M, Mir JF, Bartrons R, Escola-Gil JC, SĂĄnchez-Infantes D, Zorzano A, Llorente-Cortes V, Casals N, ValentĂ­ V, FrĂŒhbeck G, Herrero L, Serra D (2020) Liver CPT1A gene therapy reduces diet-induced hepatic steatosis in mice and highlights potential lipid biomarkers for human NAFLD. FASEB J 34:11816-37.MouseLiver
Stankova 2020 Int J Mol Sci2020StaƈkovĂĄ P, Kučera O, PeterovĂĄ E, LotkovĂĄ H, Maseko TE, NoĆŸičkovĂĄ K, ČervinkovĂĄ Z (2020) Adaptation of mitochondrial substrate flux in a mouse model of nonalcoholic fatty liver disease. Int J Mol Sci 21:E1101.MouseLiver
Fuchs 2020 J Funct Foods2020Fuchs C, Bakuradze T, Steinke R, Grewal R, Eckert GP, Richling E (2020) Polyphenolic composition of extracts from winery by-products and effects on cellular cytotoxicity and mitochondrial functions in HepG2 cells. J Funct Foods 70:103988.HumanLiver
Purhonen 2020 Nat Commun2020Purhonen J, Grigorjev V, Ekiert R, Aho N, Rajendran J, Pietras R, Truvé K, Wikström M, Sharma V, Osyczka A, Fellman V, KallijÀrvi J (2020) A spontaneous mitonuclear epistasis converging on Rieske Fe-S protein exacerbates complex III deficiency in mice. Nat Commun 11:322.MouseLiver
Kidney
Fuller 2020 J Appl Physiol (1985)2020Fuller KNZ, McCoin CS, Allen J, Bell-Glenn S, Koestler DC, Dorn Ii GW, Thyfault JP (2020) Sex and BNIP3 genotype, rather than acute lipid injection, modulate hepatic mitochondrial function and steatosis risk in mice. J Appl Physiol (1985) 128:1251-61.MouseLiver
Lensu 2020 Nutrients2020Lensu S, Pariyani R, MÀkinen E, Yang B, Saleem W, Munukka E, Lehti M, Driuchina A, Lindén J, Tiirola M, Lahti L, Pekkala S (2020) Prebiotic xylo-oligosaccharides ameliorate high-fat-diet-induced hepatic steatosis in rats . Nutrients 12:E3225.RatLiver
Gruenig 2020 Biochem Pharmacol2020GrĂŒnig D, Szabo L, Marbet M, KrĂ€henbĂŒhl S (2020) Valproic acid affects fatty acid and triglyceride metabolism in HepaRG cells exposed to fatty acids by different mechanisms. Biochem Pharmacol 177:113860.MouseLiver
Belosludtsev 2020 Biochimie2020Belosludtsev KN, Belosludtseva NV, Kosareva EA, Talanov EY, Gudkov SV, Dubinin MV (2020) Itaconic acid impairs the mitochondrial function by the inhibition of complexes II and IV and induction of the permeability transition pore opening in rat liver mitochondria. Biochimie 176:150-57.RatLiver
Alexopoulos 2020 Nat Commun2020Alexopoulos SJ, Chen SY, Brandon AE, Salamoun JM, Byrne FL, Garcia CJ, Beretta M, Olzomer EM, Shah DP, Philp AM, Hargett SR, Lawrence RT, Lee B, Sligar J, Carrive P, Tucker SP, Philp A, Lackner C, Turner N, Cooney GJ, Santos WL, Hoehn KL (2020) Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice. Nat Commun 11:2397.MouseSkeletal muscle
Liver
Fat
Nascimento-Dos-Santos 2020 Biochim Biophys Acta Mol Basis Dis2020Nascimento-Dos-Santos G, de-Souza-Ferreira E, Lani R, de Faria CC, Araujo VG, Teixeira-Pinheiro LC, de Souza Vasconcelos T, Leandro TG, Santiago MF, Linden R, Galina A, Petrs-Silva H (2020) Neuroprotection from optic nerve injury and modulation of oxidative metabolism by transplantation of active mitochondria to the retina. Biochim Biophys Acta Mol Basis Dis 1866:165686.RatLiver
Nervous system
Sowton 2020 Mol Genet Metab Rep2020Sowton AP, Padmanabhan N, Tunster SJ, McNally BD, Murgia A, Yusuf A, Griffin JL, Murray AJ, Watson ED (2020) Mtrr hypomorphic mutation alters liver morphology, metabolism and fuel storage in mice. Mol Genet Metab Rep 23:100580.MouseLiver
McLaughlin 2020b Sci Rep2020McLaughlin KL, Hagen JT, Coalson HS, Nelson MAM, Kew KA, Wooten AR, Fisher-Wellman KH (2020) Novel approach to quantify mitochondrial content and intrinsic bioenergetic efficiency across organs. Sci Rep 10:17599.MouseHeart
Liver
Kidney
Fat
Scrima 2020 bioRxiv2020Scrima R, Fugetto S, Capitanio N, Gatti DL (2020) Hemoglobin non-equilibrium oxygen dissociation curve. bioRxiv https://doi.org/10.1101/2020.01.09.900001.RatLiver
Piel 2020 PLoS One2020Piel S, Chamkha I, Dehlin AK, Ehinger JK, Sjövall F, Elmér E, Hansson MJ (2020) Cell-permeable succinate prodrugs rescue mitochondrial respiration in cellular models of acute acetaminophen overdose. PLoS One 15:e0231173.HumanLiver
Platelet
Visavadiya 2020 Mol Cell Biochem2020Visavadiya NP, Pena GS, Khamoui AV (2020) Mitochondrial dynamics and quality control are altered in a hepatic cell culture model of cancer cachexia. Mol Cell Biochem 476:23-34.MouseLiver
Zhu 2019 Aging Cell2019Zhu B, Li Y, Xiang L, Zhang J, Wang L, Guo B, Liang M, Chen L, Xiang L, Dong J, Liu M, Mei W, Li H, Xiang G (2019) Alogliptin improves survival and health of mice on a high-fat diet. Aging Cell 18:e12883.MouseLiver
Yan 2019 Int Immunopharmacol2019Yan M, Yu Y, Mao X, Feng J, Wang Y, Chen H, Xie K, Yu Y (2019) Hydrogen gas inhalation attenuates sepsis-induced liver injury in a FUNDC1-dependent manner. Int Immunopharmacol 71:61-7.MouseLiver
Azevedo 2019 Food Chem Toxicol2019Azevedo LF, Porto Dechandt CR, Cristina de Souza Rocha C, Hornos Carneiro MF, Alberici LC, Barbosa F Jr (2019) Long-term exposure to bisphenol A or S promotes glucose intolerance and changes hepatic mitochondrial metabolism in male Wistar rats. Food Chem Toxicol 132:110694.RatLiver
Ferreira 2019 EMBO J2019Ferreira N, Perks KL, Rossetti G, Rudler DL, Hughes LA, Ermer JA, Scott LH, Kuznetsova I, Richman TR, Narayana VK, Abudulai LN, Shearwood AJ, Cserne Szappanos H, Tull D, Yeoh GC, Hool LC, Filipovska A, Rackham O (2019) Stress signaling and cellular proliferation reverse the effects of mitochondrial mistranslation. EMBO J 38:e102155.MouseHeart
Liver
Madlala 2019 Integr Food Nutr Metab2019Madlala HP, Maarman GJ, Ojuka E (2019) Fructose impairs mitochondrial respiration and substrate utilization in hepatocytes via the enzyme, glutamate oxaloacetate transaminase. Integr Food Nutr Metab doi: 10.15761/IFNM.1000228.HumanLiver
Belosludtsev 2019 Biochim Biophys Acta Biomembr2019Belosludtsev KN, Belosludtseva NV, Talanov EY, Tenkov KS, Starinets VS, Agafonov AV, Pavlik LL, Dubinin MV (2019) Effect of bedaquiline on the functions of rat liver mitochondria. Biochim Biophys Acta Biomembr 1861:288-97.RatLiver
Tomasic 2019 Biochim Biophys Acta Mol Basis Dis2019TomaĆĄić N, Kotarsky H, de Oliveira Figueiredo R, Hansson E, Mörgelin M, TomaĆĄić I, KallijĂ€rvi J, ElmĂ©r E, Jauhiainen M, Eklund EA, Fellman V (2019) Fasting reveals largely intact systemic lipid mobilization mechanisms in respiratory chain complex III deficient mice. Biochim Biophys Acta Mol Basis Dis 1866:165573.MouseLiver
Hamraz 2019 FASEB J2019Hamraz M, Abolhassani R, Andriamihaja M, Ransy C, Lenoir V, Schwartz L, Bouillaud F (2019) Hypertonic external medium represses cellular respiration and promotes Warburg/Crabtree effect. FASEB J 34:222-36.Other mammals
Human
Rat
Endothelial;epithelial;mesothelial cell
Liver
HEK
Neuroblastoma
Kakimoto 2019 PLoS One2019Kakimoto PA, Chausse B, Caldeira da Silva CC, Donato JĂșnior J, Kowaltowski AJ (2019) Resilient hepatic mitochondrial function and lack of iNOS dependence in diet-induced insulin resistance. PLoS One 14:e0211733.MouseLiver
Zhang 2019 Biochem Biophys Res Commun2019Zhang WY, Hu XF, Wan N, Zhang JF, Yang P, Wen Q, Chen WJ, Zhu F, Liang ML, Cheng LX, Shu YW (2019) Protective effect of the glucagon-like peptide-1 analogue liraglutide on carbon tetrachloride-induced acute liver injury in mice. Biochem Biophys Res Commun 514:386-92.MouseLiver
Wang 2019 Free Radic Biol Med2019Wang SQ, Yang XY, Cui SX, Gao ZH, Qu XJ (2019) Heterozygous knockout insulin-like growth factor-1 receptor (IGF-1R) regulates mitochondrial functions and prevents colitis and colorectal cancer. Free Radic Biol Med 134:87-98.MouseHeart
Liver
Endothelial;epithelial;mesothelial cell
Dall 2019 J Biol Chem2019Dall M, Trammell SAJ, Asping M, Hassing AS, Agerholm M, Vienberg SG, Gillum MP, Larsen S, Treebak JT (2019) Mitochondrial function in liver cells is resistant to perturbations in NAD+ salvage capacity. J Biol Chem 294:13304-26.MouseLiver
Esselun 2019 Oxid Med Cell Longev2019Esselun C, Bruns B, Hagl S, Grewal R, Eckert GP (2019) Differential effects of silibinin A on mitochondrial function in neuronal PC12 and HepG2 liver cells. Oxid Med Cell Longev 2019:1652609.Human
Rat
Nervous system
Liver
Trefts 2019 Am J Physiol Endocrinol Metab2019Trefts E, Hughey CC, Lantier L, Lark DS, Boyd KL, Pozzi A, Zent R, Wasserman DH (2019) Energy metabolism couples hepatocyte integrin-linked kinase to liver glucoregulation and the postabsorptive response of mice in an age-dependent manner. Am J Physiol Endocrinol Metab 316:1118-35.MouseLiver
Zhang 2019 Redox Biol2019Zhang Y, Bharathi SS, Beck ME, Goetzman ES (2019) The fatty acid oxidation enzyme long-chain acyl-CoA dehydrogenase can be a source of mitochondrial hydrogen peroxide. Redox Biol 26:101253.MouseLiver
Chroeis 2019 Basic Clin Pharmacol Toxicol2019Chroeis KM, Larsen S, Pedersen JS, Rygg MO, Boilsen AEB, Bendtsen F, Dela F (2019) Acetaminophen toxicity induces mitochondrial complex I inhibition in human liver tissue. https://doi.org/10.1111/bcpt.13304HumanLiver
Adeyemi 2019 Ecotoxicol Environ Saf2019Adeyemi JA, Machado ART, Ogunjimi AT, Alberici LC, Antunes LMG, Barbosa F Jr (2019) Cytotoxicity, mutagenicity, oxidative stress and mitochondrial impairment in human hepatoma (HepG2) cells exposed to copper oxide, copper-iron oxide and carbon nanoparticles. Ecotoxicol Environ Saf 189:109982.HumanLiver
Halbach 2019 Am J Physiol Regul Integr Comp Physiol2019Halbach JL, Prieto JM, Wang AW, Hawisher D, Cauvi DM, Reyes T, Okerblom J, Ramirez-Sanchez I, Villarreal F, Patel HH, Bickler SW, Perdrizet GA, De Maio A (2019) Early hyperbaric oxygen therapy improves survival in a model of severe sepsis. Am J Physiol Regul Integr Comp Physiol 317:R160-R168.MouseLiver
Sambeat 2019 Nat Commun2019Sambeat A, Ratajczak J, Joffraud M, Sanchez-Garcia JL, Giner MP, Valsesia A, Giroud-Gerbetant J, Valera-Alberni M, Cercillieux A, Boutant M, Kulkarni SS, Moco S, Canto C (2019) Endogenous nicotinamide riboside metabolism protects against diet-induced liver damage. Nat Commun 10:4291.MouseSkeletal muscle
Liver
Paumelle 2019 J Hepatol2019Paumelle R, Haas J, Hennuyer N, Bauge E, Deleye Y, Mesotten D, Langouche L, Vanhoutte J, Cudejko C, Wouters K, Hannou SA, Legry V, Lancel S, Lalloyer F, Polizzi A, Smati S, Gourdy P, Vallez E, Bouchaert E, Derudas B, Dehondt H, Gheeraert C, Fleury S, Tailleux A, Montagner A, Wahli W, Van Den Berghe G, Guillou H, Dombrowicz D, Staels B (2019) Hepatic PPARα is critical in the metabolic adaptation to sepsis. J Hepatol 70:963-73.HumanLiver
Trefts 2019 Thesis2019Trefts E (2019) Integrin linked kinase is critical for hepatic cellular organization, metabolism, and glucoregulation. PhD Thesis 164.MouseLiver
Simon 2019 J Biol Chem2019Simon MC, Reinbeck AL, Wessel C, Heindirk J, Jelenik T, Kaul K, Arreguin-Cano J, Strom A, Blaut M, BĂ€ckhed F, Burkart V, Roden M (2019) Distinct alterations of gut morphology and microbiota characterize accelerated diabetes onset in non-obese diabetic mice. J Biol Chem 295:969-80.MouseSkeletal muscle
Liver
Rutai 2019 Shock2019Rutai A, Fejes R, Juhåsz L, Tallósy SP, Poles MZ, Földesi I, Mészåros AT, Szabó A, Boros M, Kaszaki J (2019) Endothelin A and B receptors: Potential pargets for microcirculatory-mitochondrial therapy in experimental sepsis. Shock 54:87-95.RatLiver
Thomas 2019 Redox Biol2019Thomas NO, Shay KP, Hagen TM (2019) Age-related loss of mitochondrial glutathione exacerbates menadione-induced inhibition of Complex I. Redox Biol 22:101155.RatLiver
Dlaskova 2019 Biochim Biophys Acta Bioenerg2019DlaskovĂĄ A, Ć paček T, EngstovĂĄ H, Ć pačkovĂĄ J, Schröfel A, HolendovĂĄ B, SmolkovĂĄ K, PlecitĂĄ-HlavatĂĄ L, JeĆŸek P (2019) Mitochondrial cristae narrowing upon higher 2-oxoglutarate load. Biochim Biophys Acta Bioenerg 1860:659-78.HumanLiver
Datzmann 2019 Pharmacol Res2019Datzmann T, Hoffmann A, McCook O, Merz T, Wachter U, Preuss J, Vettorazzi S, Calzia E, Gröger M, Kohn F, Schmid A, Denoix N, Radermacher P, Wepler M (2019) Effects of sodium thiosulfate (Na2S2O3) during resuscitation from hemorrhagic shock in swine with preexisting atherosclerosis. Pharmacol Res 151:104536.PigHeart
Liver
Kidney
Alvarez 2019 Chem Biol Interact2019Álvarez Santos MR, Duarte YB, GĂŒiza FM, Romero BohĂłrquez AR, Mendez-Sanchez SC (2019) Effects of new tetrahydroquinoline-isoxazole hybrides on bioenergetics of hepatocarcinoma Hep-G2 cells and rat liver mitochondria. Chem Biol Interact 302:164-71.HumanLiver
Zhao 2019 Pharmacol Res2019Zhao X, Jin Y, Li L, Xu L, Tang Z, Qi Y, Yin L, Peng J (2019) MicroRNA-128-3p aggravates doxorubicin-induced liver injury by promoting oxidative stress via targeting Sirtuin-1. Pharmacol Res 146:104276.MouseLiver
Other cell lines
Martines 2019 Sci Rep2019Martines AMF, Gerding A, Stolle S, Vieira-Lara MA, Wolters JC, Jurdzinski A, Bongiovanni L, de Bruin A, van der Vlies P, van der Vries G, Bloks VW, Derks TGJ, Reijngoud DJ, Bakker BM (2019) Transcriptome analysis suggests a compensatory role of the cofactors coenzyme A and NAD+ in medium-chain acyl-CoA dehydrogenase knockout mice. Sci Rep 9:14539.MouseLiver
Naszai 2019 Sci Rep2019NĂĄszai A, Terhes E, Kaszaki J, Boros M, JuhĂĄsz L (2019) Ca(2+)N it be measured? Detection of extramitochondrial calcium movement with high-resolution FluoRespirometry. Sci Rep 9:19229.RatLiver
Rodriguez-Enriquez 2019 Toxicol Appl Pharmacol2019Rodríguez-Enríquez S, Pacheco-Velåzquez SC, Marín-Hernåndez Á, Gallardo-Pérez JC, Robledo-Cadena DX, Hernåndez-Reséndiz I, García-García JD, Belmont-Díaz J, López-Marure R, Hernåndez-Esquivel L, Sånchez-Thomas R, Moreno-Sånchez R (2019) Resveratrol inhibits cancer cell proliferation by impairing oxidative phosphorylation and inducing oxidative stress. Toxicol Appl Pharmacol 370:65-77.RatHeart
Liver
Kunz 2019 Am J Physiol Endocrinol Metab2019Kunz HE, Dasari S, Lanza IR (2019) EPA and DHA elicit distinct transcriptional responses to high-fat feeding in skeletal muscle and liver. Am J Physiol Endocrinol Metab 317:E460-E472.MouseSkeletal muscle
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Kharechkina 2019 Biochim Biophys Acta Gen Subj2019Kharechkina ES, Nikiforova AB, Teplova VV, Odinokova IV, Krestinina OV, Baburina YL, Kruglova SA, Kruglov AG (2019) Regulation of permeability transition pore opening in mitochondria by external NAD(H). Biochim Biophys Acta Gen Subj 1863:771-83.RatLiver
Belosludtsev 2019 Cells2019Belosludtsev KN, Talanov EY, Starinets VS, Agafonov AV, Dubinin MV, Belosludtseva NV (2019) Transport of Ca2+ and Ca2+-dependent permeability transition in rat liver mitochondria under the streptozotocin-induced type I Diabetes. Cells 8:E1014.RatLiver
Tiebe 2019 Sci Rep2019Tiebe M, Lutz M, Senyilmaz Tiebe D, Teleman AA (2019) Crebl2 regulates cell metabolism in muscle and liver cells. Sci Rep 9:19869.MouseSkeletal muscle
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Halle 2019 Am J Physiol Regul Integr Comp Physiol2019Halle JL, Pena GS, Paez HG, Castro AJ, Rossiter HB, Visavadiya NP, Whitehurst MA, Khamoui AV (2019) Tissue-specific dysregulation of mitochondrial respiratory capacity and coupling control in colon-26 tumor-induced cachexia. Am J Physiol Regul Integr Comp Physiol 317:R68-R82.MouseSkeletal muscle
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Fat
Rajendran 2019 EMBO Mol Med2019Rajendran J, Purhonen J, Tegelberg S, Smolander OP, Mörgelin M, Rozman J, Gailus-Durner V, Fuchs H, Hrabe de Angelis M, Auvinen P, Mervaala E, Jacobs HT, Szibor M, Fellman V, KallijÀrvi J (2019) Alternative oxidase-mediated respiration prevents lethal mitochondrial cardiomyopathy. EMBO Mol Med 11:e9456.MouseLiver
Kidney
Heart
Salin 2019 Proc Biol Sci2019Salin K, Villasevil EM, Anderson GJ, Lamarre SG, Melanson CA, McCarthy I, Selman C, Metcalfe NB (2019) Differences in mitochondrial efficiency explain individual variation in growth performance. Proc Biol Sci 286:20191466.FishesSkeletal muscle
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Garcia-Roche 2019 PLoS One2019GarcĂ­a-Roche M, Casal A, Mattiauda DA, Ceriani M, Jasinsky A, Mastrogiovanni M, Trostchansky A, Carriquiry M, Cassina A, Quijano C (2019) Impaired hepatic mitochondrial function during early lactation in dairy cows: Association with protein lysine acetylation. PLoS One 14:e0213780.BovinesLiver
Fang 2019 Nat Commun2019Fang EF, Hou Y, Lautrup S, Jensen MB, Yang B, SenGupta T, Caponio D, Khezri R, Demarest TG, Aman Y, Figueroa D, Morevati M, Lee HJ, Kato H, Kassahun H, Lee JH, Filippelli D, Okur MN, Mangerich A, Croteau DL, Maezawa Y, Lyssiotis CA, Tao J, Yokote K, Rusten TE, Mattson MP, Jasper H, Nilsen H, Bohr VA (2019) NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome. Nat Commun 10:5284.MouseHeart
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Liver
Kappler 2019 Am J Physiol Endocrinol Metab2019Kappler L, Hoene M, Hu C, von Toerne C, Li J, Bleher D, Hoffmann C, Böhm A, Kollipara L, Zischka H, Königsrainer A, HÀring HU, Peter A, Xu G, Sickmann A, Hauck SM, Weigert C, Lehmann R (2019) Linking bioenergetic function of mitochondria to tissue-specific molecular fingerprints. Am J Physiol Endocrinol Metab 317:E374-E387.Human
Mouse
Skeletal muscle
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Mazzoli 2019 Nutrients2019Mazzoli A, Crescenzo R, Cigliano L, Spagnuolo MS, Cancelliere R, Gatto C, Iossa S (2019) Early hepatic oxidative stress and mitochondrial changes following western diet in middle aged rats. Nutrients 11:E2670.RatLiver
Courtes 2019 Biomed Pharmacother2019Courtes AA, de Carvalho NR, Gonçalves DF, Hartmann DD, da Rosa PC, Dobrachinski F, Franco JL, de Souza DOG, Soares FAA (2019) Guanosine protects against Ca2+-induced mitochondrial dysfunction in rats. Biomed Pharmacother 111:1438-46.RatLiver
McCoin 2019 Am J Physiol Endocrinol Metab2019McCoin CS, Von Schulze A, Allen J, Fuller KN, Xia Q, Koestler DC, Houchen CJ, Maurer A, Dorn Ii GW, Shankar K, Morris EM, Thyfault JP (2019) Sex modulates hepatic mitochondrial adaptations to high fat diet and physical activity. Am J Physiol Endocrinol Metab 317:E298-E311.MouseLiver
Okoye 2019 Aquat Toxicol2019Okoye CN, MacDonald-Jay N, Kamunde C (2019) Effects of bioenergetics, temperature and cadmium on liver mitochondria reactive oxygen species production and consumption. Aquat Toxicol 214:105264.FishesLiver
Petiz 2018 Chem Biol Interact2018Petiz LL, Pires ADRA, Echevarria A, Rodrigues-Santos CE, Eliane Merlin Rocha M, Acco A, Cadena SMSC (2018) Effects of a new antiprotozoal drug, N,N'-diphenyl-4-methoxy-benzamidine, on energy-linked functions of rat liver mitochondria. Chem Biol Interact 279:34-42.RatLiver
Bryant 2018 Thesis2018Bryant HJ (2018) The role of mitochondrial uncoupling in temperature responses in Atlantic killifish, Fundulus heteroclitus. Master's Thesis p126.FishesNervous system
Liver
Fat
Ravasz 2018 Biochim Biophys Acta2018Ravasz D, Kacso G, Fodor V, Horvath K, Adam-Vizi V, Chinopoulos C (2018) Reduction of 2-methoxy-1,4-naphtoquinone by mitochondrially-localized Nqo1 yielding NAD+ supports substrate-level phosphorylation during respiratory inhibition. Biochim Biophys Acta 1859:909-24.MouseLiver
Kovalcikova 2018 Thesis2018Kovalčíková J (2018) Functional characterisation of new components of mitochondrial proteome. PhD Thesis p104.Mouse
Rat
Heart
Liver
Menezes-Filho 2018 Biochim Biophys Acta Bioenerg2018Menezes-Filho SL, Amigo I, Luévano-Martínez LA, Kowaltowski AJ (2018) Fasting promotes functional changes in liver mitochondria. Biochim Biophys Acta Bioenerg 1860:129-35.MouseLiver
Bjoerndal 2018 Nutr Metab (Lond)2018BjÞrndal B, AlterÄs EK, Lindquist C, Svardal A, Skorve J, Berge RK (2018) Associations between fatty acid oxidation, hepatic mitochondrial function, and plasma acylcarnitine levels in mice. Nutr Metab (Lond) 15:10.MouseLiver
Chung 2018 J Exp Biol2018Chung DJ, Sparagna GC, Chicco AJ, Schulte PM (2018) Patterns of mitochondrial membrane remodeling parallel functional adaptations to thermal stress. J Exp Biol 221. pii: jeb174458.FishesLiver
Qu 2018 FASEB J2018Qu C, Zhang S, Wang W, Li M, Wang Y, van der Heijde-Mulder M, Shokrollahi E, Hakim MS, Raat NJH, Peppelenbosch MP, Pan Q (2018) Mitochondrial electron transport chain complex III sustains hepatitis E virus replication and represents an antiviral target. FASEB J 33:1008-19.HumanLiver
Seite 2018 Sci Rep2018Seite S, Mourier A, Camougrand N, Salin B, Figueiredo-Silva AC, Fontagne-Dicharry S, Panserat S, Seiliez I (2018) Dietary methionine deficiency affects oxidative status, mitochondrial integrity and mitophagy in the liver of rainbow trout (Oncorhynchus mykiss). Sci Rep 8:10151.FishesLiver
Budai 2018 Br J Surg2018Budai A, HorvĂĄth G, Tretter L, RadĂĄk Z, Koltai E, Bori Z, Torma F, LukĂĄts Á, Röhlich P, SzijĂĄrtĂł A, FĂŒlöp A (2018) Mitochondrial function after associating liver partition and portal vein ligation for staged hepatectomy in an experimental model. Br J Surg 106:120-31.RatLiver
Ost 2018 Curr Opin Clin Nutr Metab Care2018Ost M, Doerrier C, Gama-Perez P, Moreno-Gomez S (2018) Analysis of mitochondrial respiratory function in tissue biopsies and blood cells. Curr Opin Clin Nutr Metab Care 21:336-42.Blood cells
Platelet
Skeletal muscle
Liver
Fat
Mills 2018 Nature2018Mills EL, Ryan DG, Prag HA, Dikovskaya D, Menon D, Zaslona Z, Jedrychowski MP, Costa ASH, Higgins M, Hams E, Szpyt J, Runtsch MC, King MS, McGouran JF, Fischer R, Kessler BM, McGettrick AF, Hughes MM, Carroll RG, Booty LM, Knatko EV, Meakin PJ, Ashford MLJ, Modis LK, Brunori G, SĂ©vin DC, Fallon PG, Caldwell ST, Kunji ERS, Chouchani ET, Frezza C, Dinkova-Kostova AT, Hartley RC, Murphy MP, O'Neill LA (2018) Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. Nature 556:113-7.RatLiver
Manoharan 2018 Thesis2018Manoharan N (2018) Characterization of mitochondrial respiration in atlantic salmon (Salmo salar) fed with glutamate and succinate enhanced diet. Master's Thesis 52.FishesHeart
Liver
Kamunde 2018 Free Radic Biol Med2018Kamunde C, Sharaf M, MacDonald N (2018) H2O2 metabolism in liver and heart mitochondria: Low emitting-high scavenging and high emitting-low scavenging systems. Free Radic Biol Med 124:135-48.FishesHeart
Liver
Von Schulze 2018 J Physiol2018Von Schulze A, McCoin CS, Onyekere C, Allen J, Geiger P, Dorn GW, Morris EM, Thyfault JP (2018) Hepatic mitochondrial adaptations to physical activity: impact of sexual dimorphism, PGC1α, and BNIP3 mediated mitophagy. J Physiol 596:6157-71.MouseLiver
Pape 2018 Nutrients2018Pape JA, Newey CR, Burrell HR, Workman A, Perry K, Bikman BT, Bridgewater LC, Grose JH (2018) Per-Arnt-Sim kinase (PASK) deficiency increases cellular respiration on a standard diet and decreases liver triglyceride accumulation on a western high-fat high-sugar diet. Nutrients 10:1990.MouseSkeletal muscle
Liver
Collard 2018 Mol Cell Biol2018Collard R, Majtan T, Park I, Kraus JP (2018) Import of TAT-conjugated propionyl coenzyme A carboxylase using models of propionic acidemia. Mol Cell Biol 38. pii: e00491-17.MouseLiver
Kappler 2018 Thesis2018Kappler L (2018) Method development for valid high‐resolution profiling of mitochondria and Omics investigation of mitochondrial adaptions to excess energy intake and physical exercise. Dissertation p181.Human
Mouse
Skeletal muscle
Liver
Other cell lines
Davila 2018 Elife2018Davila A, Liu L, Chellappa K, Redpath P, Nakamaru-Ogiso E, Paolella LM, Zhang Z, Migaud ME, Rabinowitz JD, Baur JA (2018) Nicotinamide adenine dinucleotide is transported into mammalian mitochondria. Elife 7:e33246.MouseSkeletal muscle
Liver
Belosludtsev 2018 Biochemistry (Mosc)2018Belosludtsev KN, Belosludtseva NV, Tenkov KS, Sharapov VA, Kosareva EA, Dubinin MV (2018) Effect of dequalinium on respiration and the inner membrane permeability of rat liver mitochondria. Biochemistry (Mosc) 12:121–27.RatLiver
Wu 2018 Adv Sci2018Wu S, Zhang A, Li S, Chatterjee S, Qi R, Segura-Ibarra V, Ferrari M, Gupte A, Blanco E, Hamilton DJ (2018) Polymer functionalization of isolated mitochondria for cellular transplantation and metabolic phenotype alteration. Adv Sci 1700530.MouseLiver
Dechandt 2018 Am J Physiol Regul Integr Comp Physiol2018Dechandt CR, Vicentini TM, Lanfredi GP, da Silva RMP Jr, Espreafico EM, de Oliveira JAC, Faça VM, Garcia-Cairasco N, Alberici LC (2018) The highly efficient power house in the Wistar Audiogenic Rat (WAR), an epileptic rat strain. Am J Physiol Regul Integr Comp Physiol 316:R243-R254.RatHeart
Skeletal muscle
Liver
Porceddu 2018 Methods Pharmacol Toxicol2018Porceddu M, Buron N, Rustin P, Fromenty B, Borgne-Sanchez A (2018) In vitro assessment of mitochondrial toxicity to predict drug-induced liver injury. Methods Pharmacol Toxicol Drug-Induced Liver Toxicity:283-300.Liver
Paech 2018a Toxicology2018Paech F, Mingard C, GrĂŒnig D, Abegg VF, Bouitbir J, KrĂ€henbĂŒhl S (2018) Mechanisms of mitochondrial toxicity of the kinase inhibitors ponatinib, regorafenib and sorafenib in human hepatic HepG2 cells. Toxicology 395:34-44.Human
Mouse
Liver
Other cell lines
Bricambert 2018 Nat Commun2018Bricambert J, Alves-Guerra MC, Esteves P, Prip-Buus C, Bertrand-Michel J, Guillou H, Chang CJ, Vander Wal MN, Canonne-Hergaux F, Mathurin P, Raverdy V, Pattou F, Girard J, Postic C, Dentin R (2018) The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity. Nat Commun 9:2092.MouseLiver
Rajasekaran 2018 FASEB J2018Rajasekaran R, Felser A, Nuoffer JM, Dufour JF, St-Pierre MV (2018) The histidine triad nucleotide-binding protein 2 (HINT-2) positively regulates hepatocellular energy metabolism. FASEB J 32:5143-61.MouseLiver
Goncalves 2018 Life Sci2018Gonçalves DF, de Carvalho NR, Leite MB, Courtes AA, Hartmann DD, Stefanello ST, da Silva IK, Franco JL, Soares FAA, Dalla Corte CL (2018) Caffeine and acetaminophen association: Effects on mitochondrial bioenergetics. Life Sci 193:234-41.MouseLiver
Kauppila 2018 Thesis2018Kauppila JHK (2018) Generating mammalian mitochondrial disease models with mitochondrial DNA mutations. PhD Thesis p120.MouseHeart
Liver
Fernandes-Siqueira 2018 mSphere2018Fernandes-Siqueira LO, Zeidler JD, Sousa BG, Ferreira T, Da Poian AT (2018) Anaplerotic role of glucose in the oxidation of endogenous fatty acids during Dengue virus infection. mSphere 3.pii: e00458-17.HumanLiver
Other cell lines
Marinho 2018 Evid Based Complement Alternat Med2018Marinho PC, Vieira AB, Pereira PG, Rabelo K, Ciambarella BT, Nascimento ALR, Cortez E, Moura AS, GuimarĂŁes FV, Martins MA, Barquero G, Ferreira RN, de Carvalho JJ (2018) Capybara oil improves hepatic mitochondrial dysfunction, steatosis, and inflammation in a murine model of nonalcoholic fatty liver disease. Evid Based Complement Alternat Med 2018:4956079.MouseLiver
Belosludtsev 2018 Biochim Biophys Acta2018Belosludtsev KN, Belosludtseva NV, Talanov EY, Tenkov KS, Starinets VS, Agafonov AV, Pavlik LL, Dubinin MV (2018) Effect of bedaquiline on the functions of rat liver mitochondria. Biochim Biophys Acta 1861:288-97.RatLiver
Houghton 2018 Free Radic Biol Med2018Houghton MJ, Kerimi A, Tumova S, Boyle JP, Williamson G (2018) Quercetin preserves redox status and stimulates mitochondrial function in metabolically-stressed HepG2 cells. Free Radic Biol Med 129:296-309.HumanLiver
Garcia-Roche 2018 Redox Biol2018GarcĂ­a-Roche M, Casal A, Carriquiry M, Radi R, Celia Quijano C, Cassina A (2018) Respiratory analysis of coupled mitochondria in cryopreserved liver biopsies. Redox Biol 17:207-12.Rat
Bovines
Liver
Paech 2018b Toxicology2018Paech F, Abegg VF, Duthaler U, Terracciano L, Bouitbir J, KrĂ€henbĂŒhl S (2018) Sunitinib induces hepatocyte mitochondrial damage and apoptosis in mice. Toxicology 409:13-23.MouseLiver
Apostolopoulou 2018 Thesis2018Apostolopoulou M (2018) Determinants of insulin sensitivity in obesity and recent-onset type 2 diabetes mellitus. PhD Thesis 77.HumanLiver
Fouret 2018 Br J Nutr2018Fouret G, Gaillet S, Lecomte J, Bonafos B, Djohan F, Barea B, Badia E, Coudray C, Feillet-Coudray C (2018) 20-Week follow-up of hepatic steatosis installation and liver mitochondrial structure and activity and their interrelation in rats fed a high-fat-high-fructose diet. Br J Nutr 119:368-80.RatLiver
Hughey 2018 J Biol Chem2018Hughey CC, Trefts E, Bracy DP, James FD, Donahue EP, Wasserman DH (2018) Glycine N-methyltransferase deletion in mice diverts carbon flux from gluconeogenesis to pathways that utilize excess methionine cycle intermediates. J Biol Chem 293:11944-54.MouseLiver
Mayer 2018 Endocrinology2018Mayer AL, Zhang Y, Feng EH, Higgins CB, Adenekan O, Pietka TA, Beatty WL, DeBosch BJ (2018) Enhanced hepatic PPARα activity links GLUT8 deficiency to augmented peripheral fasting responses in male mice. Endocrinology 159:2110-26.MouseSkeletal muscle
Liver
Einer 2018 Cell Mol Gastroenterol Hepatol2018Einer C, Leitzinger C, Lichtmannegger J, Eberhagen C, Rieder T, Borchard S, Wimmer R, Denk G, Popper B, Neff F, Polishchuk EV, Polishchuk RS, Hauck SM, von Toerne C, MĂŒller JC, Karst U, Baral BS, DiSpirito AA, Kremer AE, Semrau J, Weiss KH, Hohenester S, Zischka H (2018) A high calorie diet aggravates mitochondrial dysfunction and triggers severe liver damage in Wilson disease rats. Cell Mol Gastroenterol Hepatol 7:571-96.RatLiver
Pless-Petig 2018 Cell Transplant2018Pless-Petig G, Walter B, Bienholz A, Rauen U (2018) Mitochondrial impairment as a key factor for the lack of attachment after cold storage of hepatocyte suspensions. Cell Transplant 26:1855-67.RatLiver
Chung 2018 Integr Comp Biol2018Chung DJ, Healy TM, McKenzie JL, Chicco AJ, Sparagna GC, Schulte PM (2018) Mitochondria, temperature, and the pace of life. Integr Comp Biol 58:578-90.FishesHeart
Nervous system
Liver
Wang 2018 Mol Med Rep2018Wang B, Li W, Fang H, Zhou H (2018) Hepatitis B virus infection is not associated with fatty liver disease: Evidence from a cohort study and functional analysis. Mol Med Rep 19:320-26. https://doi.org/10.3892/mmr.2018.9619HumanLiver
Becker 2018 EMBO Rep2018Becker C, Kukat A, Szczepanowska K, Hermans S, Senft K, Brandscheid CP, Maiti P, Trifunovic A (2018) CLPP deficiency protects against metabolic syndrome but hinders adaptive thermogenesis. EMBO Rep 19. pii: e45126.MouseLiver
Fat
Casal 2018 J Anim Sci2018Casal A, Garcia-Roche M, Navajas EA, Cassina A, Carriquiry M (2018) Hepatic mitochondrial function in Hereford steers with divergent residual feed intake phenotypes. J Anim Sci 96:4431-43.BovinesLiver
Hayward 2018 Thesis2018Hayward L (2018) The effect of anoxia on mitochondrial function in a hibernator (Ictidomys tridecemlineatus). Master's Thesis 57.Other mammalsLiver
De Sales 2018 Molecules2018de Sales NFF, Silva da Costa L, Carneiro TIA, Minuzzo DA, Oliveira FL, Cabral LMC, Torres AG, El-Bacha T (2018) Anthocyanin-rich grape pomace extract (Vitis vinifera L.) from wine industry affects mitochondrial bioenergetics and glucose metabolism in human hepatocarcinoma HepG2 cells. Molecules 23.HumanLiver
Other cell lines
Cecatto 2018 J Cell Biochem2018Cecatto C, Wajner A, Vargas CR, Wajner SM, Amaral AU, Wajner M (2018) High vulnerability of the heart and liver to 3-hydroxypalmitic acid-induced disruption of mitochondrial functions in intact cell systems. J Cell Biochem 119:7678-86.RatHeart
Nervous system
Liver
Sims 2018 JCI Insight2018Sims CA, Guan Y, Mukherjee S, Singh K, Botolin P, Davila A Jr, Baur JA (2018) Nicotinamide mononucleotide preserves mitochondrial function and increases survival in hemorrhagic shock. JCI Insight 3:120182.RatLiver
Kidney
Magnifico 2018 Oxid Med Cell Longev2018Magnifico MC, Xhani M, Popov M, Saso L, Sarti P, Arese M (2018) Nonylphenol and octylphenol differently affect cell redox balance by modulating the nitric oxide signaling. Oxid Med Cell Longev 2018:1684827.HumanLiver
Other cell lines
Salin 2018 Funct Ecol2018Salin K, Villasevil EM, Anderson GJ, Auer SK, Selman C, Hartley RC, Mullen W, Chinopoulos C, Metcalfe NB (2018) Decreased mitochondrial metabolic requirements in fasting animals carry an oxidative cost. Funct Ecol DOI: 10.1111/1365-2435.13125.FishesLiver
Lu 2018 Cell Discov2018Lu Z, Wei X, Sun F, Zhang H, Gao P, Pu Y, Wang A, Chen J, Tong W, Li Q, Zhou X, Yan Z, Zheng H, Yang G, Huang Y, Liu D, Zhu Z (2018) Non-insulin determinant pathways maintain glucose homeostasis upon metabolic surgery. Cell Discov 4:58.RatSkeletal muscle
Liver
Rossignoli 2018 J Nutr Biochem2018Rossignoli CP, Dechandt CRP, Souza AO, Sampaio IH, Vicentini TM, Teodoro BG, Neto MPC, Ferrari GD, Couto-Lima CA, Alberici LC (2018) Effects of intermittent dietary supplementation with conjugated linoleic acid and fish oil (EPA/DHA) on body metabolism and mitochondrial energetics in mice. J Nutr Biochem 60:16-23.MouseSkeletal muscle
Nervous system
Liver
Fat
Kleszczynski 2018 Int J Mol Sci2018KleszczyƄski K, Bilska B, Stegemann A, Flis DJ, Ziolkowski W, Pyza E, Luger TA, Reiter RJ, Böhm M, Slominski AT (2018) Melatonin and its metabolites ameliorate UVR-induced mitochondrial oxidative stress in human MNT-1 melanoma cells. Int J Mol Sci 19:E3786.MouseLiver
Woodman 2018 FASEB J2018Woodman AG, Mah R, Keddie D, Noble RMN, Panahi S, Gragasin FS, Lemieux H, Bourque SL (2018) Prenatal iron deficiency causes sex-dependent mitochondrial dysfunction and oxidative stress in fetal rat kidneys and liver. FASEB J 32:3254-63.RatLiver
Kidney
Rundle 2018 Environ Sci Technol2018Rundle K, Sharaf M, Stevens D, Kamunde C, Van Den Heuvel MR (2018) Oil sands-derived naphthenic acids are oxidative uncouplers and impair electron transport in isolated mitochondria. Environ Sci Technol 52:10803-11.FishesLiver
Du 2018 Environ Sci Technol2018Du SNN, McCallum ES, Vaseghi-Shanjani M, Choi JA, Warriner TR, Balshine S, Scott GR (2018) Metabolic costs of exposure to wastewater effluent lead to compensatory adjustments in respiratory physiology in bluegill sunfish. Environ Sci Technol 52:801-11.FishesLiver
Van Erp 2018 Sci Rep2018Van Erp AC, Rebolledo RA, Hoeksma D, Jespersen NR, Ottens PJ, NĂžrregaard R, Pedersen M, Laustsen C, Burgerhof JGM, Wolters JC, Ciapaite J, BĂžtker HE, Leuvenink HGD, Jespersen B (2018) Organ-specific responses during brain death: increased aerobic metabolism in the liver and anaerobic metabolism with decreased perfusion in the kidneys. Sci Rep 8:4405.RatLiver
Kidney
Salin 2018 Integr Comp Biol2018Salin K, Villasevil EM, Anderson GJ, Selman C, Chinopoulos C, Metcalfe NB (2018) The RCR and ATP/O indices can give contradictory messages about mitochondrial efficiency. Integr Comp Biol 58:486-94.FishesLiver
Stolf 2018 Biomed Pharmacother2018Stolf AM, Campos Cardoso C, Morais H, Alves de Souza CE, Lomba LA, Brandt AP, Agnes JP, Collere FC, Galindo CM, Corso CR, Spercoski KM, Locatelli Dittrich R, Zampronio AR, Cadena SMSC, Acco A (2018) Effects of silymarin on angiogenesis and oxidative stress in streptozotocininduced diabetes in mice. Biomed Pharmacother 108:232-43.MouseLiver
Schatton 2017 J Cell Biol2017Schatton D, Pla-Martin D, Marx MC, Hansen H, Mourier A, Nemazanyy I, Pessia A, Zentis P, Corona T, Kondylis V, Barth E, Schauss AC, Velagapudi V, Rugarli EI (2017) CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs. J Cell Biol 216:675-93.MouseLiver
Varga 2017 Inflammopharmacology2017Varga G, Ugocsai M, Hartmann P, LajkĂł N, MolnĂĄr R, SzƱcs S, JĂĄsz DK, Érces D, Ghyczy M, TĂłth G, Boros M (2017) Acetylsalicylic acid-tris-hydroxymethyl-aminomethane reduces colon mucosal damage without causing gastric side effects in a rat model of colitis. Inflammopharmacology 26:261-71.RatLiver
Sharaf 2017 Aquat Toxicol2017Sharaf MS, Stevens D, Kamunde C (2017) Zinc and calcium alter the relationship between mitochondrial respiration, ROS and membrane potential in rainbow trout (Oncorhynchus mykiss) liver mitochondria. Aquat Toxicol 189:170-83.FishesLiver
Dechandt 2017 J Bioenerg Biomembr2017Dechandt CRP, Zuccolotto-Dos-Reis FH, Teodoro BG, Fernandes AMAP, Eberlin MN, Kettelhut IC, Curti C, Alberici LC (2017) Triacsin C reduces lipid droplet formation and induces mitochondrial biogenesis in primary rat hepatocytes. J Bioenerg Biomembr 49:399-411.RatLiver
Jeong 2017 Exp Mol Med2017Jeong JH, Cheol Kang Y, Piao Y, Kang S, Pak YK (2017) miR-24-mediated knockdown of H2AX damages mitochondria and the insulin signaling pathway. Exp Mol Med 49:e313.HumanLiver
Merz 2017 Intensive Care Med Exp2017Merz T, Vogt JA, Wachter U, Calzia E, Szabo C, Wang R, Radermacher P, McCook O (2017) Impact of hyperglycemia on cystathionine-Îł-lyase expression during resuscitated murine septic shock. Intensive Care Med Exp 5:30.MouseLiver
Selwood 2017 US Patent2017Selwood DL, Baker D, Szabadkai G, Duchen MR, Hill JM, Warne JND (2017) Quinolium conjugates of cyclosporin. US Patent US20170349632 A1.MouseLiver
Ravasz 2017 Neurochem Int2017Ravasz D, Kacso G, Fodor V, Horvath K, Adam-Vizi V, Chinopoulos C (2017) Catabolism of GABA, succinic semialdehyde or gamma-hydroxybutyrate through the GABA shunt impair mitochondrial substrate-level phosphorylation. Neurochem Int 109:41-53.MouseNervous system
Liver
Nemeth 2017 Thesis2017NĂ©meth B (2017) The effect of itaconic acid on mitochondrial substrate-level phosphorylation. PhD Thesis p84.MouseLiver
Gruenig 2017 Toxicol In Vitro2017GrĂŒnig D, Felser A, Bouitbir J, KrĂ€henbĂŒhl S (2017) The catechol-O-methyltransferase inhibitors tolcapone and entacapone uncouple and inhibit the mitochondrial respiratory chain in HepaRG cells. Toxicol In Vitro 42:337-47.Human
Mouse
Liver
Other cell lines
Heim 2017 Am J Physiol Regul Integr Comp Physiol2017Heim AB, Chung D, Florant GL, Chicco AJ (2017) Tissue-specific seasonal changes in mitochondrial function of a mammalian hibernator. Am J Physiol Regul Integr Comp Physiol 313:R180-90.Other mammalsHeart
Skeletal muscle
Liver
Fat
Gonzalez-Durruthy 2017 Nanomaterials (Basel)2017Gonzålez-Durruthy M, Monserrat JM, Rasulev B, Casañola-Martín GM, Barreiro Sorrivas JM, Paraíso-Medina S, Maojo V, Gonzålez-Díaz H, Pazos A, Munteanu CR (2017) Carbon nanotubes' effect on mitochondrial oxygen flux dynamics: polarography experimental study and machine learning models using star graph trace invariants of raman spectra. Nanomaterials (Basel) 7. pii: E386.RatLiver
Thomas 2017 Thesis2017Thomas NO (2017) Age-related decrease in resilience against acute redox cycling agents: critical role of declining GSH-dependent detoxification capacity. Dissertation p141.RatLiver
Kudin 2017 Int J Mol Sci2017Kudin AP, Mawasi H, Eisenkraft A, Elger CE, Bialer M, Kunz WS (2017) Mitochondrial liver toxicity of valproic acid and its acid derivatives is related to inhibition of α-lipoamide dehydrogenase. Int J Mol Sci 18. pii: E1912.RatNervous system
Liver
Anderson 2017 Cell Metab2017Anderson KA, Huynh FK, Fisher-Wellman K, Stuart JD, Peterson BS, Douros JD, Wagner GR, Thompson JW, Madsen AS, Green MF, Sivley RM, Ilkayeva OR, Stevens RD, Backos DS, Capra JA, Olsen CA, Campbell JE, Muoio DM, Grimsrud PA, Hirschey MD (2017) SIRT4 is a lysine deacylase that controls leucine metabolism and insulin secretion. Cell Metab 25:838-55.MouseHeart
Liver
Yeh 2017 Aquat Toxicol2017Yeh A, Marcinek DJ, Meador JP, Gallagher EP (2017) Effect of contaminants of emerging concern on liver mitochondrial function in Chinook salmon. Aquat Toxicol 190:21-31.FishesLiver
Fink 2017 Pharmacol Res Perspect2017Fink BD, Guo DF, Kulkarni CA, Rahmouni K, Kerns RJ, Sivitz WI (2017) Metabolic effects of a mitochondrial-targeted coenzyme Q analog in high fat fed obese mice. Pharmacol Res Perspect 5:e00301.MouseLiver
Jelenik 2017 Diabetes2017Jelenik T, Kaul K, SĂ©quaris G, Flögel U, Phielix E, Kotzka J, Knebel B, Fahlbusch P, Hörbelt T, Lehr S, Reinbeck AL, MĂŒller-Wieland D, Esposito I, Shulman GI, Szendroedi J, Roden M (2017) Mechanisms of insulin resistance in primary and secondary nonalcoholic fatty liver. Diabetes 66:2241-53.MouseSkeletal muscle
Liver
Valis 2017 Oncotarget2017ValiĆĄ K, GrobĂĄrovĂĄ V, HernychovĂĄ L, BugåƈovĂĄ M4, Kavan D, Kalous M, ČernĂœ J, StodĆŻlkovĂĄ E, Kuzma M, Flieger M, ČernĂœ J, NovĂĄk P (2017) Reprogramming of leukemic cell metabolism through the naphthoquinonic compound Quambalarine B. Oncotarget 8:103137-53.RatLiver
Xhani 2017 Thesis2017Xhani M (2017) Cellular redox homeostasis and environmental toxicity. Dissertation p110.HumanLiver
Other cell lines
Zhang 2017 J Biol Chem2017Zhang Y, Bharathi SS, Rardin MJ, Lu J, Maringer KV, Sims-Lucas S, Prochownik EV, Gibson BW, Goetzman ES (2017) Lysine desuccinylase SIRT5 binds to cardiolipin and regulates the electron transport chain. J Biol Chem 292:10239-49.HumanLiver
HEK
Jackson 2017 Cancer Res2017Jackson LE, Kulkarni S, Wang H, Lu J, Dolezal JM, Bharathi SS, Ranganathan S, Patel MS, Deshpande R, Alencastro F, Wendell SG, Goetzman ES, Duncan AW, Prochownik EV (2017) Genetic dissociation of glycolysis and the TCA cycle affects neither normal nor neoplastic proliferation. Cancer Res 77:5795-807.MouseLiver
Buck 2017 PLOS ONE2017Buck E, ZĂŒgel M, Schumann U, Merz T, Gumpp AM, Witting A, Steinacker JM, Landwehrmeyer GB, Weydt P, Calzia E, Lindenberg KS (2017) High-resolution respirometry of fine-needle muscle biopsies in pre-manifest Huntington's disease expansion mutation carriers shows normal mitochondrial respiratory function. PLOS ONE 12:e0175248.Human
Mouse
Heart
Skeletal muscle
Nervous system
Liver
Luethi 2017 Toxicology2017Luethi D, Liechti ME, KrĂ€henbĂŒhl S (2017) Mechanisms of hepatocellular toxicity associated with new psychoactive synthetic cathinones. Toxicology 387:57-66.HumanLiver
Cunha-de 2017 Thesis2017Cunha-de Padua MM (2017) Mecanismos citotĂłxicos da galactomanana de sementes de Schizolobium amazonicum e seus complexos com oxovanĂĄdio em cĂ©lulas de hepatocarcinoma humano (HepG2) e efeito do silenciamento da enzima glucose-6-fosfato isomerase (GPI) na sobrevivĂȘncia de cĂ©lulas de adenocarcinoma de cĂłlon humano (LS174T). Doctoral Thesis p160.HumanLiver
Other cell lines
Paech 2017 Arch Toxicol2017Paech F, Messner S, Spickermann J, Wind M, Schmitt-Hoffmann AH, Witschi AT, Howell BA, Church RJ, Woodhead J, Engelhardt M, KrĂ€henbĂŒhl S, Maurer M (2017) Mechanisms of hepatotoxicity associated with the monocyclic ÎČ-lactam antibiotic BAL30072. Arch Toxicol 91:3647-62.HumanLiver
Other cell lines
Yeh 2017 Thesis2017Yeh A (2017) Modulation of mitochondrial function as an indicator for sublethal effects of contaminants of emerging concern. Dissertation p117.Human
Fishes
Liver
Chung 2017 Sci Rep2017Chung DJ, Morrison PR, Bryant HJ, Jung E, Brauner CJ, Schulte PM (2017) Intraspecific variation and plasticity in mitochondrial oxygen binding affinity as a response to environmental temperature. Sci Rep 7:16238.FishesLiver
Wollenman 2017 PLOS ONE2017Wollenman LC, Vander Ploeg MR, Miller ML, Zhang Y, Bazil JN (2017) The effect of respiration buffer composition on mitochondrial metabolism and function. PLOS ONE 12:e0187523.Guinea pigHeart
Liver
Rademann 2017 Oxid Med Cell Longev2017Rademann P, Weidinger A, Drechsler S, Meszaros A, Zipperle J, Jafarmadar M, Dumitrescu S, Hacobian A, Ungelenk L, Röstel F, Kaszaki J, Szabo A, Skulachev VP, Bauer M, Bahrami S, Weis S, Kozlov AV, Osuchowski MF (2017) Mitochondria-targeted antioxidants SKQ1 and MitoTEMPO failed to exert a long-term beneficial effect in murine polymicrobial sepsis. Oxid Med Cell Longev 6412682.Mouse
Rat
Liver
Dolezal 2017 J Biol Chem2017Dolezal JM, Wang H, Kulkarni S, Jackson L, Lu J, Ranganathan S, Goetzman ES, Bharathi SS, Beezhold K, Byersdorfer CA, Prochownik EV (2017) Sequential adaptive changes in a c-Myc-driven model of hepatocellular carcinoma. J Biol Chem 292:10068-86.MouseLiver
Volani 2017 Metallomics2017Volani C, Doerrier C, Demetz E, Haschka D, Paglia G, Lavdas AA, Gnaiger E, Weiss G (2017) Dietary iron loading negatively affects liver mitochondrial function. Metallomics 9:1634-44.MouseLiver
Mathers 2017 J Comp Physiol B2017Mathers KE, McFarlane SV, Zhao L, Staples JF (2017) Regulation of mitochondrial metabolism during hibernation by reversible suppression of electron transport system enzymes. J Comp Physiol B 187:227-34.Other mammalsLiver
Menezes-Filho 2017 Free Radic Biol Med2017Menezes-Filho SL, Amigo I, Prado FM, Ferreira NC, Koike MK, Pinto IFD, Miyamoto S, Montero EFS, Medeiros MHG, Kowaltowski AJ (2017) Caloric restriction protects livers from ischemia/reperfusion damage by preventing Ca2+-induced mitochondrial permeability transition. Free Radic Biol Med 110:219-27.MouseLiver
Krycer 2017 Biochem Biophys Res Commun2017Krycer JR, Fisher-Wellman KH, Fazakerley DJ, Muoio DM, James DE (2017) Bicarbonate alters cellular responses in respiration assays. Biochem Biophys Res Commun 489:399-403.MouseLiver
Fat
Tuboly 2017 Sci Rep2017Tuboly E, MolnĂĄr R, TƑkĂ©s T, TurĂĄnyi RN, Hartmann P, MĂ©szĂĄros AT, Strifler G, Földesi I, Siska A, SzabĂł A, MohĂĄcsi Á, SzabĂł G, Boros M (2017) Excessive alcohol consumption induces methane production in humans and rats. Sci Rep 7:7329.RatNervous system
Liver
Cunha 2017 Int J Biol Macromol2017Cunha de Padua MM, Suter Correia Cadena SM, de Oliveira Petkowicz CL, Martinez GR, Rodrigues Noleto G (2017) Galactomannan from Schizolobium amazonicum seed and its sulfated derivatives impair metabolism in HepG2 cells. Int J Biol Macromol 101:64-473.HumanLiver
Linden 2016 Am J Physiol Gastrointest Liver Physiol2017Linden MA, Fletcher JA, Meers GM, Thyfault JP, Laughlin MH, Rector RS (2017) A return to ad libitum feeding following caloric restriction promotes hepatic steatosis in hyperphagic OLETF rats. Am J Physiol Gastrointest Liver Physiol 311:G387-95.RatLiver
Jezek 2017 Biochim Biophys Acta2017JeĆŸek J, EngstovĂĄ H, JeĆŸek P (2017) Antioxidant mechanism of mitochondria-targeted plastoquinone SkQ1 is suppressed in aglycemic HepG2 cells dependent on oxidative phosphorylation. Biochim Biophys Acta 1858:750-62.HumanLiver
De Velasco 2017 Br J Nutr2017de Velasco PC, Chicaybam G, Ramos-Filho DM, Dos Santos RMAR, Mairink C, Sardinha FLC, El-Bacha T, Galina A, Tavares-do-Carmo MDG (2017) Maternal intake of trans-unsaturated or interesterified fatty acids during pregnancy and lactation modifies mitochondrial bioenergetics in the liver of adult offspring in mice. Br J Nutr 118:41-52.MouseLiver
Rouet 2017 US Patent2017Rouet P, Smih F (2017) ApoO for use in method for treating cancer and various pathophysiological situations. US Patent US20170035842 A1.Human
Mouse
Heart
Liver
Haegler 2017 PLOS ONE2017Haegler P, GrĂŒnig D, Berger B, Terracciano L, KrĂ€henbĂŒhl S, Bouitbir J (2017) Hepatic effects of pharmacological doses of hydroxy-cobalamin[c-lactam] in mice. PLOS ONE 12:e0171026.MouseLiver
Teplova 2017 Toxicol Lett2017Teplova VV, Belosludtsev KN, Kruglov AG (2017) Mechanism of triclosan toxicity: Mitochondrial dysfunction including complex II inhibition, superoxide release and uncoupling of oxidative phosphorylation. Toxicol Lett 275:108-17.RatLiver
Sobotka 2017 Thesis2017Sobotka O (2017) Pharmacological and metabolic influence on liver mitochondrial functions. PhD Thesis p127.Mouse
Rat
Liver
Hartmann 2017 Crit Care Med2017Hartmann C, Loconte M, Antonucci E, Holzhauser M, Hölle T, Katzsch D, Merz T, McCook O, Wachter U, Vogt JA, Hoffmann A, Wepler M, Gröger M, Matejovic M, Calzia E, Georgieff M, Asfar P, Radermacher P, Nussbaum BL (2017) Effects of hyperoxia during resuscitation from hemorrhagic shock in swine with preexisting coronary artery disease. Crit Care Med 45:e1270-9.PigHeart
Liver
Kidney
Du 2017 Evolution2017Du SNN, Khajali F, Dawson NJ, Scott GR (2017) Hybridization increases mitochondrial production of reactive oxygen species in sunfish. Evolution 71:1643-52.FishesLiver
Sharaf 2017 Biochim Biophys Acta2017Sharaf MS, Stevens D, Kamunde C (2017) Mitochondrial transition ROS spike (mTRS) results from coordinated activities of complex I and nicotinamide nucleotide transhydrogenase. Biochim Biophys Acta 1858:955-65.Mouse
Fishes
Heart
Liver
Perks 2017 Sci Adv2017Perks KL, Ferreira N, Richman TR, Ermer JA, Kuznetsova I, Shearwood AJ, Lee RG, Viola HM, Johnstone VPA, Matthews V, Hool LC, Rackham O, Filipovska A (2017) Adult-onset obesity is triggered by impaired mitochondrial gene expression. Sci Adv 3:e1700677.MouseHeart
Liver
De Lourdes Jorge 2017 Transplant Proc2017de Lourdes Jorge G, Dos Reis TĂĄrtaro R, Fazzio Escanhoela CA, Boin IFSF (2017) Later evaluation of ischemia and reperfusion by the Pringle maneuver in Wistar rats, demonstrating that hepatic lesions can be reversible. Transplant Proc 49:898-901.RatLiver
Schoenfeld 2017 Neurochem Int2017Schönfeld P, Reiser G (2017) Brain energy metabolism spurns fatty acids as fuel due to their inherent mitotoxicity and potential capacity to unleash neurodegeneration. Neurochem Int 109:68-77.RatNervous system
Liver
Briston 2017 Sci Rep2017Briston T, Roberts M, Lewis S, Powney B, M Staddon J, Szabadkai G, Duchen MR (2017) Mitochondrial permeability transition pore: sensitivity to opening and mechanistic dependence on substrate availability. Sci Rep 7:10492.RatLiver
Cunha de Padua 2017 Carbohydr Polym2017Cunha de Padua MM, Suter Correia Cadena SM, de Oliveira Petkowicz CL, Martinez GR, Rodrigues Noleto G (2017) Toxicity of native and oxovanadium (IV/V) galactomannan complexes on HepG2 cells is related to impairment of mitochondrial functions. Carbohydr Polym 173:665-75.HumanLiver
Cecatto 2017 Neurochem Int2017Cecatto C, Amaral AU, da Silva JC, Wajner A, Godoy KD, Ribeiro RT, Gonçalves AM, Vargas CR, Wajner M (2017) Mevalonolactone disrupts mitochondrial functions and induces permeability transition pore opening in rat brain mitochondria: Implications for the pathogenesis of mevalonic aciduria. Neurochem Int 108:133-45.RatNervous system
Liver
Bohanon 2017 Shock2017Bohanon FJ, Lopez ON, Herndon DN, Wang X, Bhattarai N, Ayadi AE, Prasai A, Jay JW, Rojas-Khalil Y, Toliver-Kinsky TE, Finnerty CC, Radhakrishnan RS, Porter C (2017) Burn trauma acutely increases the respiratory capacity and function of liver mitochondria. Shock 49:466-73.MouseLiver
Salin 2016 Physiol Biochem Zool2016Salin K, Auer SK, Rudolf AM, Anderson GJ, Selman C, Metcalfe NB (2016) Variation in metabolic rate among individuals is related to tissue-specific differences in mitochondrial LEAK respiration. Physiol Biochem Zool 89:511-23.FishesSkeletal muscle
Liver
Gariani 2016 Hepatology2016Gariani K, Menzies KJ, Ryu D, Wegner CJ, Wang X, Ropelle ER, Moullan N, Zhang H, Perino A, Lemos V, Kim B, Park YK, Piersigilli A, Pham TX, Yang Y, Ku SC, Koo SI, Fomitchova A, CantĂł C, Schoonjans K, Sauve AA, Lee JY, Auwerx J (2016) Eliciting the mitochondrial unfolded protein response via NAD+ repletion reverses fatty liver disease. Hepatology 63:1190-204.MouseLiver
Chu 2016 World J Gastroenterol2016Chu MJ, Premkumar R, Hickey AJ, Jiang Y, Delahunt B, Phillips AR, Bartlett A (2016) Steatotic livers are susceptible to normothermic ischemia-reperfusion injury from mitochondrial Complex-I dysfunction. World J Gastroenterol 22:4673-84.RatLiver
Ojuka 2016 Am J Physiol Endocrinol Metab2016Ojuka E, Andrew B, Bezuidenhout N, George S, Maarman G, Madlala HP, Mendham A, Osiki PO (2016) Measurement of ÎČ-oxidation capacity of biological samples by respirometry: a review of principles and substrates. Am J Physiol Endocrinol Metab 310:E715-23. https://doi.org/10.1152/ajpendo.00475.2015Human
Mouse
Rat
Skeletal muscle
Liver
Zelenka 2016 Oxid Med Cell Longev2016Zelenka J, Dvoƙák A, Alán L, Zadinová M, Haluzík M, Vítek L (2016) Hyperbilirubinemia protects against aging-associated inflammation and metabolic deterioration. Oxid Med Cell Longev ID 6190609:10p.RatLiver
Kidney
Fibroblast
Smith 2016 Diabetes2016Smith BK, Ford RJ, Desjardins EM, Green AE, Hughes MC, Houde VP, Day EA, Marcinko K, Crane JD, Mottillo EP, Perry CG, Kemp BE, Tarnopolsky MA, Steinberg GR (2016) Salsalate (Salicylate) uncouples mitochondria, improves glucose homeostasis, and reduces liver lipids independent of AMPK ÎČ1. Diabetes 65:3352-61.MouseSkeletal muscle
Liver
Fat
Strifler 2016 Magyar Sebeszet2016Strifler G, Meszaros A, Pecz D, Ficzere A, Barath B, Mihaly B, Hartmann P (2016) A mĂĄjfunkciĂł vizsgĂĄlata respirometriĂĄval - Examination of liver mitochondria with respirometry. Magyar SebĂ©szet 69:194–8.RatLiver
Scrima 2016 Biochim Biophys Acta2016Scrima R, Cela O, Merla G, Augello B, Rubino R, Quarato G, Fugetto S, Menga M, Fuhr L, RelĂłgio A, Piccoli C, Mazzoccoli G, Capitanio N (2016) Clock-genes and mitochondrial respiratory activity: Evidence of a reciprocal interplay. Biochim Biophys Acta 1857:1344-51.HumanLiver
Endothelial;epithelial;mesothelial cell
Other cell lines
Fibroblast
Salin 2016 J Exp Biol2016Salin K, Auer SK, Anderson GJ, Selman C, Metcalfe NB (2016) Inadequate food intake at high temperatures is related to depressed mitochondrial respiratory capacity. J Exp Biol 219:1356-62.FishesSkeletal muscle
Liver
Khmil 2016 International Symposium Mitochondrial Motility2016Khmil NV, Mosencov AA, Ovsyannikova TN, Dyachenko VD, Goncharenko MS, Kolomytkin OV, Mironova GD (2016) Influence of oranoselenium compounds on functioning of rat liver mitochondria. International Symposium Mitochondrial Motility 96-100.RatLiver
Moore 2016 Cryobiology2016Moore DS, Hand SC (2016) Cryopreservation of lipid bilayers by LEA proteins from Artemia franciscana and trehalose. Cryobiology 73:240-7.RatLiver
Briston 2016 Sci Rep2016Briston T, Lewis S, Koglin M, Mistry K, Shen Y, Hartopp N, Katsumata R, Fukumoto H, Duchen MR, Szabadkai G, Staddon JM, Roberts M, Powney B (2016) Identification of ER-000444793, a Cyclophilin D-independent inhibitor of mitochondrial permeability transition, using a high-throughput screen in cryopreserved mitochondria. Sci Rep 6:37798.RatLiver
Van Zutphen 2016 J Hepatol2016van Zutphen T, Ciapaite J, Bloks VW, Ackereley C, Gerding A, Jurdzinski A, Allgayer de Moraes R, Zhang L, Wolters JC, Bischoff R, Wanders RJA, Houten SM, Bronte-Tinkew D, Shatseva T, Lewis GF, Groen AK, Reijngoud DJ, Bakker BM, Jonker JW, Kim PK, Bandsma RH (2016) Malnutrition-associated liver steatosis and ATP depletion is caused by peroxisomal and mitochondrial dysfunction. J Hepatol 65:1198-1208.RatLiver
Peleli 2016 Free Radic Biol Med2016Peleli M, Zollbrecht C, Montenegro MF, Hezel M, Zhong J, Persson EG, Holmdahl R, Weitzberg E, Lundberg JO, Carlström M (2016) Enhanced XOR activity in eNOS-deficient mice: Effects on the nitrate-nitrite-NO pathway and ROS homeostasis. Free Radic Biol Med 99:472-84.MouseLiver
Mezera 2016 Oxid Med Cell Longev2016Mezera V, Endlicher R, Kucera O, Sobotka O, Drahota Z, Cervinkova Z (2016) Effects of epigallocatechin gallate on tert-butyl hydroperoxide-induced mitochondrial dysfunction in rat liver mitochondria and hepatocytes. Oxid Med Cell Longev 7573131:8pp.RatLiver
Amaral 2016 Biochim Biophys Acta2016Amaral AU, Cecatto C, da Silva JC, Wajner A, Godoy KD, Ribeiro RT, Wajner M (2016) cis-4-Decenoic and decanoic acids impair mitochondrial energy, redox and Ca2+ homeostasis and induce mitochondrial permeability transition pore opening in rat brain and liver: Possible implications for the pathogenesis of MCAD deficiency. Biochim Biophys Acta 1857:1363-72.RatNervous system
Liver
De Carvalho 2016 J Cell Biochem2016de Carvalho AK, da Silva S, Serafini E, de Souza DR, Farias HR, de Bem Silveira G, Silveira PC, de Souza CT, Portela LV, Muller AP (2016) Prior exercise training prevent hyperglycemia in STZ mice by increasing hepatic glycogen and mitochondrial function on skeletal muscle. J Cell Biochem 118:678-85.MouseSkeletal muscle
Liver
Kucera 2016 Drug Chem Toxicol2016Kučera O, Endlicher R, Rychtrmoc D, Lotková H, Sobotka O, Červinková Z (2016) Acetaminophen toxicity in rat and mouse hepatocytes in vitro. Drug Chem Toxicol 40:448-56.Mouse
Rat
Liver
Lund 2016 J Physiol2016Lund MT, Kristensen M, Hansen M, Tveskov L, Floyd AK, StĂžckel M, Vainer B, Poulsen SS, Helge JW, Prats C, Dela F (2016) Hepatic mitochondrial oxidative phosphorylation is normal in obese patients with and without type 2 diabetes. J Physiol 594:4351-8.HumanLiver
Gorbacheva 2016 International Symposium Mitochondrial Motility2016Gorbacheva OS, Strutynskyi RB, Khmil NV, Belosludtseva NV, Murzaeva SV, Korobeynikova MO, Alilova GA, Lezhnev EI, Mironova GD (2016) Study of the influence of flocalin on the energy and ion exchanges in rat liver mitochondria. International Symposium Mitochondrial Motility 73-7.RatLiver
Hawley 2016 Diabetes2016Hawley SA, Ford RJ, Smith BK, Gowans GJ, Mancini SJ, Pitt RD, Day EA, Salt IP, Steinberg GR, Hardie DG (2016) The Na+/glucose cotransporter inhibitor canagliflozin activates AMPK by inhibiting mitochondrial function and increasing cellular AMP levels. Diabetes 65:2784-94.Human
Mouse
Liver
HEK
Heim 2016 Thesis2016Heim A (2016) Tissue-specific seasonal changes in mitochondrial respiratory function and membrane composition in the golden-matled ground squirrel. Master's Thesis p77.Other mammalsHeart
Skeletal muscle
Liver
Fat
Reijne 2016 PLOS ONE2016Reijne AC, Ciapaite J, van Dijk TH, Havinga R, van der Zee EA, Groen AK, Reijngoud DJ, Bakker BM, van Dijk G (2016) Whole-body vibration partially reverses aging-induced increases in visceral adiposity and hepatic lipid storage in mice. PLOS ONE 11:e0149419.MouseSkeletal muscle
Liver
Van Eunen 2016 BMC Biol2016van Eunen K, Volker-Touw CM, Gerding A, Bleeker A, Wolters JC, van Rijt WJ, Martines AM, Niezen-Koning KE, Heiner RM, Permentier H, Groen AK, Reijngoud DJ, Derks TG, Bakker BM (2016) Living on the edge: substrate competition explains loss of robustness in mitochondrial fatty-acid oxidation disorders. BMC Biol 14:107.MouseLiver
Camacho-Pereira 2016 Cell Metab2016Camacho-Pereira J, TarragĂł MG, Chini CC, Nin V, Escande C, Warner GM, Puranik AS, Schoon RA, Reid JM, Galina A, Chini EN (2016) CD38 dictates age-related NAD decline and mitochondrial dysfunction through an SIRT3-dependent mechanism. Cell Metab 23:1127-39.Human
Mouse
Liver
Lung;gill
Other cell lines
Strifler 2016 PLOS ONE2016Strifler G, Tuboly E, Szél E, Kaszonyi E, Cao C, Kaszaki J, Mészåros A, Boros M, Hartmann P (2016) Inhaled methane limits the mitochondrial electron transport chain dysfunction during experimental liver ischemia-reperfusion injury. PLOS ONE 11:e0146363.RatLiver
Torres 2016 Redox Biol2016Torres S, Matías N, Baulies A, Nuñez S, Alarcon-Vila C, Martinez L, Nuño N, Fernandez A, Caballeria J, Levade T, Gonzalez-Franquesa A, Garcia-Rovés P, Balboa E, Zanlungo S, Fabrías G, Casas J, Enrich C, Garcia-Ruiz C, Fernåndez-Checa JC (2016) Mitochondrial GSH replenishment as a potential therapeutic approach for Niemann Pick type C disease. Redox Biol 11:60-72.Human
Mouse
Nervous system
Liver
Endothelial;epithelial;mesothelial cell
Fibroblast
Peyta 2016 Biochim Biophys Acta2016Peyta L, Jarnouen K, Pinault M, Guimaraes C, Pais de Barros JP, Chevalier S, Dumas JF, Maillot F, Hatch GM, Loyer P, Servais S (2016) Reduced cardiolipin content decreases respiratory chain capacities and increases ATP synthesis yield in the human HepaRG cells. Biochim Biophys Acta 1857:443-53.HumanLiver
Other cell lines
Jardim-Messeder 2016 Anticancer Res2016Jardim-Messeder D, Moreira-Pacheco F (2016) 3-Bromopyruvic acid inhibits tricarboxylic acid cycle and glutaminolysis in HepG2 cells. Anticancer Res 36:2233-41.MouseLiver
Kidney
Nemeth 2016 FASEB J2016Németh B, Doczi J, Csete D, Kacso G, Ravasz D, Adams D, Kiss G, Nagy AM, Horvath G, Tretter L, Mócsai A, Csépånyi-Kömi R, Iordanov I, Adam-Vizi V, Chinopoulos C (2016) Abolition of mitochondrial substrate-level phosphorylation by itaconic acid produced by LPS-induced Irg1 expression in cells of murine macrophage lineage. FASEB J 30:286-300.MouseLiver
Kacso 2016 Biochem J2016Kacso G, Ravasz D, Doczi J, NĂ©meth B, Madgar O, Saada A, Ilin P, Miller C, Ostergaard E, Iordanov I, Adams D, Vargedo Z, Araki M, Araki K, Nakahara M, Ito H, GĂĄl A, MolnĂĄr MJ, Nagy Z, Patocs A, Adam-Vizi V, Chinopoulos C (2016) Two transgenic mouse models for ÎČ-subunit components of succinate-CoA ligase yielding pleiotropic metabolic alterations. Biochem J 473:3463-85.MouseHeart
Nervous system
Liver
Bai 2016 PLOS ONE2016Bai F, Fink BD, Yu L, Sivitz WI (2016) Voltage-dependent regulation of Complex II energized mitochondrial oxygen flux. PLOS ONE 11:e0154982.MouseHeart
Skeletal muscle
Nervous system
Liver
Shirey 2016 Biochemistry2016Shirey K, Stover KR, Cleary J, Hoang N, Hosler J (2016) Membrane-anchored cyclic peptides as effectors of mitochondrial oxidative phosphorylation. Biochemistry 55:2100-11.RatHeart
Liver
Du 2016 Thesis2016Du X (2016) Anthropogenic pollution effects on mitochondrial energy metabolism, gene expression, and genotypes of natural Fundulus heteroclitus populations. Dissertation p175.FishesLiver
Du 2016 J Exp Biol2016Du SN, Mahalingam S, Borowiec BG, Scott GR (2016) Mitochondrial physiology and reactive oxygen species production are altered by hypoxia acclimation in killifish (Fundulus heteroclitus). J Exp Biol 219:1130-8.FishesLiver
Richman 2016 Nat Commun2016Richman TR, SpÄhr H, Ermer JA, Davies SM, Viola HM, Bates KA, Papadimitriou J, Hool LC, Rodger J, Larsson NG, Rackham O, Filipovska A (2016) Loss of the RNA-binding protein TACO1 causes late-onset mitochondrial dysfunction in mice. Nat Commun 7:11884.MouseHeart
Liver
Strifler 2016b PLOS ONE2016Strifler G, Tuboly E, Görbe A, Boros M, Pécz D, Hartmann P (2016) Targeting mitochondrial dysfunction with L-alpha glycerylphosphorylcholine. PLOS ONE 11:e0166682.RatLiver
Rohlenova 2016 Antioxid Redox Signal2016Rohlenova K, Sachaphibulkij K, Stursa J, Bezawork-Geleta A, Blecha J, Endaya B, Werner L, Cerny J, Zobalova R, Goodwin J, Spacek T, Alisadeh E, Yan B, Nguyen M, Vondrusova M, Sobol M, Jezek P, Hozak P, Truksa J, Rohlena J, Dong L, Neuzil J (2016) Selective disruption of respiratory supercomplexes as a new strategy to suppress Her2high breast cancer. Antioxid Redox Signal 26:84-103.Human
Mouse
Liver
Genital
Other cell lines
Brandt 2016 Chem Biol Interact2016Brandt AP, Gozzi GJ, Pires Ado R, Martinez GR, Dos Santos Canuto AV, Echevarria A, Di Pietro A, Cadena SM (2016) Impairment of oxidative phosphorylation increases the toxicity of SYD-1 on hepatocarcinoma cells (HepG2). Chem Biol Interact 256:154-60.HumanLiver
Other cell lines
Wang 2016 J Biol Chem2016Wang H, Lu J, Edmunds LR, Kulkarni S, Dolezal J, Tao J, Ranganathan S, Jackson L, Fromherz M, Stolz DB, Uppala R, Bharathi S, Monga SP, Goetzman ES, Prochownik EV (2016) Coordinated activities of multiple Myc-dependent and Myc-independent biosynthetic pathways in Hepatoblastoma. J Biol Chem 291:26241-51.MouseLiver
Radovic 2016 Diabetologia2016Radović B, Vujić N, Leopold C, Schlager S, Goeritzer M, Patankar JV, Korbelius M, Kolb D, Reindl J, Wegscheider M, Tomin T, Birner-Gruenberger R, Schittmayer M, Groschner L, Magnes C, Diwoky C, Frank S, Steyrer E, Du H, Graier WF, Madl T, Kratky D (2016) Lysosomal acid lipase regulates VLDL synthesis and insulin sensitivity in mice. Diabetologia 59:1743-52.MouseLiver
Karlsson 2016 Shock2016Karlsson M, Hara N, Morata S, Sjövall F, Kilbaugh T, Hansson MJ, Uchino H, Elmér E (2016) Diverse and tissue-specific mitochondrial respiratory response in a mouse model of sepsis-induced multiple organ failure. Shock 45:404-10.MouseNervous system
Liver
Gariani 2016 J Hepatol2016Gariani K, Ryu D, Menzies KJ, Yi HS, Stein S, Zhang H, Perino A, Lemos V, Katsyuba E, Jha P, Vijgen S, Rubbia-Brandt L, Kim YK, Kim JT, Kim KS, Shong M, Schoonjans K, Auwerx J (2016) Inhibiting poly ADP-ribosylation increases fatty acid oxidation and protects against fatty liver disease. J Hepatol 66:132-41.MouseLiver
Boutant 2016 Cell Rep2016Boutant M, Kulkarni SS, Joffraud M, Raymond F, MĂ©tairon S, Descombes P, CantĂł C (2016) SIRT1 gain of function does not mimic or enhance the adaptations to intermittent fasting. Cell Rep 14:2068-75.MouseSkeletal muscle
Liver
Fat
Sobotka 2016 J Bioenerg Biomembr2016Sobotka O, Endlicher R, Drahota Z, Kučera O, Rychtrmoc D, Raad M, Hakeem K, Červinková Z (2016) Impaired mitochondrial functions contribute to 3-bromopyruvate toxicity in primary rat and mouse hepatocytes. J Bioenerg Biomembr 48:363-73.Mouse
Rat
Liver
Williams 2016 Diabetes2016Williams AS, Trefts E, Lantier L, Grueter C, Bracy DP, James FD, Pozzi A, Zent R, Wasserman DH (2016) Integrin-linked kinase is necessary for the development of diet-induced hepatic insulin resistance. Diabetes 66:325-34.MouseLiver
Morton 2016 Nat Med2016Morton NM, Beltram J, Carter RN, Michailidou Z, Gorjanc G, McFadden C, Barrios-Llerena ME, Rodriguez-Cuenca S, Gibbins MT, Aird RE, Moreno-Navarrete JM, Munger SC, Svenson KL, Gastaldello A, Ramage L, Naredo G, Zeyda M, Wang ZV, Howie AF, Saari A, SipilÀ P, Stulnig TM, Gudnason V, Kenyon CJ, Seckl JR, Walker BR, Webster SP, Dunbar DR, Churchill GA, Vidal-Puig A, Fernandez-Real JM, Emilsson V, Horvat S (2016) Genetic identification of thiosulfate sulfurtransferase as an adipocyte-expressed antidiabetic target in mice selected for leanness. Nat Med 22:771-9.MouseLiver
Salin 2016 Physiol Rep2016Salin K, Villasevil EM, Auer SK, Anderson GJ, Selman C, Metcalfe NB, Chinopoulos C (2016) Simultaneous measurement of mitochondrial respiration and ATP production in tissue homogenates and calculation of effective P/O ratios. Physiol Rep 10.14814/phy2.13007.FishesLiver
Liu 2016 Apoptosis2016Liu X, Gao RW, Li M, Si CF, He YP, Wang M, Yang Y, Zheng QY, Wang CY (2016) The ROS derived mitochondrial respiration not from NADPH oxidase plays key role in Celastrol against angiotensin II-mediated HepG2 cell proliferation. Apoptosis 21:1315-26.HumanLiver
Other cell lines
Du 2016 Aquat Toxicol2016Du X, Crawford DL, Nacci DE, Oleksiak MF (2016) Heritable oxidative phosphorylation differences in a pollutant resistant Fundulus heteroclitus population. Aquat Toxicol 177:44-50.FishesLiver
Renner 2016 Mycotoxin Res2016Renner L, Kahlert S, Tesch T, Bannert E, Frahm J, Barta-Böszörményi A, Kluess J, Kersten S, Schönfeld P, Rothkötter HJ, DÀnicke S (2016) Chronic DON exposure and acute LPS challenge: effects on porcine liver morphology and function. Mycotoxin Res 33:207-18.PigLiver
MiPNet17.03 Shredder vs Fibers2015-06-18
O2k-Protocols
Mitochondrial respiration in permeabilized fibers versus homogenate from fish liver and heart. An application study with the PBI-Shredder.
FishesHeart
Liver
Miwa 2015 Free Radic Biol Med2015Miwa S, Treumann A, Bell A, Vistoli G, Nelson G, Hay S, von Zglinicki T (2015) Carboxylesterase converts Amplex red to resorufin: Implications for mitochondrial H2O2 release assays. Free Radic Biol Med 90:173-83.MouseLiver
Zelenka 2015 Oxid Med Cell Longev2015Zelenka J, Dvoƙák A, Alán L (2015) L-lactate protects skin fibroblasts against aging-associated mitochondrial dysfunction via mitohormesis. Oxid Med Cell Longev 2015:351698.RatLiver
Endothelial;epithelial;mesothelial cell
Fibroblast
Doerrier 2015 Thesis2015Doerrier C (2015) Estudio bioenergetica mitochondrial en la sepsis experimental y efecto protector de la Melatonina. Doctoral Thesis p154.MouseHeart
Liver
Tartaro 2015 Transplant Proc2015TĂĄrtaro RD, Jorge GD, Leonardi MI, Escanhoela CA, Leonardi LS, Boin IF (2015) No protective function found in Wistar rats submitted to long ischemia time and reperfusion after intermittent clamping of the total hepatic pedicle. Transplant Proc 47:1038-41.RatLiver
Aroor 2015 Diabetes2015Aroor AR, Habibi J, Ford DA, Nistala R, Lastra G, Manrique C, Dunham MM, Ford KD, Thyfault JP, Parks EJ, Sowers JR, Rector RS (2015) Dipeptidyl peptidase-4 inhibition ameliorates western diet-induced hepatic steatosis and insulin resistance through hepatic lipid remodeling and modulation of hepatic mitochondrial function. Diabetes 64:1988-2001.MouseLiver
Hagve 2015 Am J Physiol Endocrinol Metab2015Hagve M, Gjessing PF, FuskevÄg OM, Larsen TS, Irtun Ø (2015) Skeletal muscle mitochondria exhibit decreased pyruvate oxidation capacity and increased ROS emission during surgery-induced acute insulin resistance. Am J Physiol Endocrinol Metab 308:E613-20.PigSkeletal muscle
Liver
Martinez 2015 Thesis2015MartĂ­nez Gasca B (2015) Generacion de modelos celulares para el estudio del efecto fenotipico de la variacion genetica en el mtDNA. Thesis 1-35.HumanLiver
Other cell lines
Tesori 2015 Sci Rep2015Tesori V, Piscaglia AC, Samengo D, Barba M, Bernardini C, Scatena R, Pontoglio A, Castellini L, Spelbrink JN, Maulucci G, Puglisi MA, Pani G, Gasbarrini A (2015) The multikinase inhibitor Sorafenib enhances glycolysis and synergizes with glycolysis blockade for cancer cell killing. Sci Rep 5:9149.RatLiver
Other cell lines
Stem cells
Bonsignore 2015 Mech Ageing Dev2015Bonsignore LA, Tooley JG, Van Hoose PM, Wang E, Cheng A, Cole MP, Schaner Tooley CE (2015) NRMT1 knockout mice exhibit phenotypes associated with impaired DNA repair and premature aging. Mech Ageing Dev 146-148:42-52.MouseLiver
Lark 2015 Front Physiol2015Lark DS, Reese LR, Ryan TE, Torres MJ, Smith CD, Lin CT, Neufer PD (2015) Protein kinase A governs oxidative phosphorylation kinetics and oxidant emitting potential at complex I. https://doi.org/10.3389/fphys.2015.00332MouseSkeletal muscle
Liver
Chweih 2015 Exp Physiol2015Chweih H, Castilho RF, Figueira TR (2015) Tissue and sex specificities in Ca(2+) handling by isolated mitochondria in conditions avoiding the permeability transition. Exp Physiol 100(9):1073-92.RatHeart
Skeletal muscle
Nervous system
Liver
Van Ewijk 2015 Obesity (Silver Spring)2015van Ewijk PA, Paglialunga S, Kooi ME, Nunes PM, Gemmink A, Slenter J, Kornips E, Jörgensen JA, Hoeks J, Wildberger JE, Hesselink MK, Glatz JF, Heerschap A, Kersten S, Schrauwen P, Schrauwen-Hinderling VB (2015) Effects of high-fat feeding on ectopic fat storage and postprandial lipid metabolism in mouse offspring. Obesity (Silver Spring) 23:2242-50.MouseHeart
Liver
Baraldi 2015 J Nutr Biochem2015Baraldi FG, Vicentini TM, Teodoro BG, Dalalio FM, Dechandt CR, Prado IM, Curti C, Cardoso FC, Uyemura SA, Alberici LC (2015) The combination of conjugated linoleic acid (CLA) and extra virgin olive oil increases mitochondrial and body metabolism and prevents CLA-associated insulin resistance and liver hypertrophy in C57Bl/6 mice. J Nutr Biochem 28:147-54.MouseLiver
Chausse 2015 PLoS One2015Chausse B, Vieira-Lara MA, Sanchez AB, Medeiros MH, Kowaltowski AJ (2015) Intermittent fasting results in tissue-specific changes in bioenergetics and redox state. PLoS One 10:e0120413.RatHeart
Skeletal muscle
Nervous system
Liver
McCommis 2015 Cell Metab2015McCommis KS, Chen Z, Fu X, McDonald WG, Colca JR, Kletzien RF, Burgess SC, Finck BN (2015) Loss of mitochondrial pyruvate carrier 2 in the liver leads to defects in gluconeogenesis and compensation via pyruvate-alanine cycling. Cell Metab 22:682-94.MouseLiver
Fouret 2015 Biochim Biophys Acta2015Fouret G, Tolika E, Lecomte J, Bonafos B, Aoun M, Murphy MP, Ferreri C, Chatgilialoglu C, Dubreucq E, Coudray C, Feillet-Coudray C (2015) The mitochondrial-targeted antioxidant, MitoQ, increases liver mitochondrial cardiolipin content in obesogenic diet-fed rats. Biochim Biophys Acta 1847:1025-35.RatLiver
Dungel 2015 Free Radic Biol Med2015Dungel P, Perlinger M, Weidinger A, Redl H, Kozlov AV (2015) The cytoprotective effect of nitrite is based on the formation of dinitrosyl iron complexes. Free Radic Biol Med 89:300-10.RatLiver
Abou-Hamdan 2015 Methods Enzymol2015Abou-Hamdan A, Guedouari-Bounihi H, Lenoir V, Andriamihaja M, Blachier F, Bouillaud F (2015) Oxidation of H2S in mammalian cells and mitochondria. Methods Enzymol 554:201-28.Human
Pig
Mouse
Rat
Heart
Nervous system
Liver
Kidney
Genital
CHO
Neuroblastoma
Fibroblast
Koliaki 2015 Cell Metab2015Koliaki C, Szendroedi J, Kaul K, Jelenik T, Nowotny P, Jankowiak F, Herder C, Carstensen M, Krausch M, Knoefel WT, Schlensak M, Roden M (2015) Adaptation of hepatic mitochondrial function in humans with non-alcoholic fatty liver is lost in steatohepatitis. Cell Metab 21:739-46.HumanLiver
Peyta 2015 Biochim Biophys Acta2015Peyta L, Jarnouen K, Pinault M, Coulouarn C, Guimaraes C, Goupille C, de Barros JP, Chevalier S, Dumas JF, Maillot F, Hatch GM, Loyer P, Servais S (2015) Regulation of hepatic cardiolipin metabolism by TNFα: Implication in cancer cachexia. Biochim Biophys Acta 1851:1490-500.RatLiver
Other cell lines
Janssens 2015 Nutr Metab (Lond)2015Janssens S, Heemskerk MM, van den Berg SA, van Riel NA, Nicolay K, Willems van Dijk K, Prompers JJ (2015) Effects of low-stearate palm oil and high-stearate lard high-fat diets on rat liver lipid metabolism and glucose tolerance. Nutr Metab (Lond) 12:57.RatLiver
Chu 2015 Liver Transpl2015Chu MJ, Hickey AJ, Jiang Y, Petzer A, Bartlett AS, Phillips AR (2015) Mitochondrial dysfunction in steatotic rat livers occurs because a defect in complex I makes the liver susceptible to prolonged cold ischemia. Liver Transpl 21:396-407.RatLiver
Haegler 2015 Toxicology2015Haegler P, GrĂŒnig D, Berger B, KrĂ€henbĂŒhl S, Bouitbir J (2015) Impaired mitochondrial function in HepG2 cells treated with hydroxy-cobalamin[c-lactam]: A cell model for idiosyncratic toxicity. Toxicology 336:48-58.HumanLiver
Other cell lines
Kucera 2015 Oxid Med Cell Longev2015Kucera O, Mezera V, Moravcova A, Endlicher R, Lotkova H, Drahota Z, Cervinkova Z (2015) In vitro toxicity of epigallocatechin gallate in rat liver mitochondria and hepatocytes. Oxid Med Cell Longev 2015:476180.RatLiver
Jeger 2015 BioMed Res Internat2015Jeger V, Brandt S, Porta F, Jakob SM, Takala J, Djafarzadeh S (2015) Dose response of Endotoxin on hepatocyte and muscle mitochondrial respiration in vitro. BioMed Res Internat Article ID 353074:1-13.HumanSkeletal muscle
Liver
Other cell lines
Bonhoure 2015 Genes Dev2015Bonhoure N, Byrnes A, Moir RD, Hodroj W, Preitner F, Praz V, Marcelin G, Chua SC Jr, Martinez-Lopez N, Singh R, Moullan N, Auwerx J, Willemin G, Shah H, Hartil K, Vaitheesvaran B, Kurland I, Hernandez N, Willis IM1 (2015) Loss of the RNA polymerase III repressor MAF1 confers obesity resistance. Genes Dev 29:934-47.MouseLiver
Ziemer 2015 Dissertation2015Ziemer M (2015) Untersuchungen zur AktivitÀt der mitochondrialen PermeabilitÀtstransitionspore in der Cyclophilin-D-Knock-out-Maus (Ppif-/-). Dissertation 1-72.MouseLiver
Sheldon 2015 Am J Physiol Gastrointest Liver Physiol2015Sheldon RD, Padilla J, Jenkins NT, Laughlin MH, Rector RS (2015) Chronic NOS inhibition accelerates NAFLD progression in an obese rat model. Am J Physiol Gastrointest Liver Physiol 308:G540-9.RatLiver
Beauchamp 2015 Biosci Rep2015Beauchamp B, Thrush AB, Quizi J, Antoun G, McIntosh N, Al-Dirbashi OY, Patti ME, Harper ME (2015) Undernutrition during pregnancy in mice leads to dysfunctional cardiac muscle respiration in adult offspring. Biosci Rep 35. pii:e00200.MouseHeart
Liver
Du 2015 Aquat Toxicol2015Du X, Crawford DL, Oleksiak MF (2015) Effects of anthropogenic pollution on the oxidative phosphorylation pathway of hepatocytes from natural populations of Fundulus heteroclitus. Aquat Toxicol 165:231-40.FishesLiver
Suarez 2015 PhD Thesis2015SuĂĄrez Cunza S (2015) Actividad captadora de Radicales libres y Effecto antioxidante de Metabolitos secundarios del extracto acuoso des "Allium sativum" var. Huaralino (Ajo) en Modelos in vitro. PhD Thesis 1-39.RatLiver
Muellebner 2015 Biomolecules2015MĂŒllebner A, Moldzio R, Redl H, Kozlov AV, Duvigneau JC (2015) Heme degradation by heme oxygenase protects mitochondria but induces ER stress via formed bilirubin. Biomolecules 5:679-701.RatLiver
Plecita-Hlavata 2015 J Bioenerg Biomembr2015PlecitĂĄ-HlavatĂĄ L, JeĆŸek J, JeĆŸek P (2015) Aglycemia keeps mitochondrial oxidative phosphorylation under hypoxic conditions in HepG2 cells. J Bioenerg Biomembr 47(6):467-76.HumanLiver
Kang 2015 Int J Clin Exp Med2015Kang M, Zhao L, Ren M, Deng M, Li C (2015) Reduced metallothionein expression induced by Zinc deficiency results in apoptosis in hepatic stellate cell line LX-2. Int J Clin Exp Med 8:20603-9.HumanLiver
Other cell lines
Tapia 2015 Crit Care2015Tapia P, Soto D, Bruhn A, AlegrĂ­a L, Jarufe N, Luengo C, Kattan E, Regueira T, Meissner A, Menchaca R, Vives MI, EcheverrĂ­a N, Ospina-TascĂłn G, Bakker J, HernĂĄndez G (2015) Impairment of exogenous lactate clearance in experimental hyperdynamic septic shock is not related to total liver hypoperfusion. Crit Care 19:188.Other mammalsLiver
Canto 2015 Curr Protoc Mouse Biol2015CantĂł C, Garcia-Roves PM (2015) High-resolution respirometry for mitochondrial characterization of ex vivo mouse tissues. Curr Protoc Mouse Biol 5:135-53.MouseHeart
Skeletal muscle
Nervous system
Liver
Fat
Patil 2015 J Nutr Biochem2015Patil YN, Dille KN, Burk DH, Cortez CC, Gettys TW (2015) Cellular and molecular remodeling of inguinal adipose tissue mitochondria by dietary methionine restriction. J Nutr Biochem 26:1235-47.MouseSkeletal muscle
Liver
Fat
Richman 2015 PLoS Genet2015Richman TR, Ermer JA, Davies SM, Perks KL, Viola HM, Shearwood AM, Hool LC, Rackham O, Filipovska A (2015) Mutation in MRPS34 compromises protein synthesis and causes mitochondrial dysfunction. PLoS Genet 11:e1005089.MouseHeart
Liver
Tomsik 2015 J Organomet Chem2015TomsĂ­k P, Muthna D, Rezacova M, Micuda S, Cmielova J, Hroch M, Endlicher R, Cervinkova Z, Rudolf E, Hann S, StĂ­bal D, Therrien B, SĂŒss-Fink G (2015) [(p-MeC6H4Pri)2Ru2(SC6H4-p-But)3]Cl (diruthenium-1), a dinuclear arene ruthenium compound with very high anticancer activity: An in vitro and in vivo study. J Organomet Chem 782:42-51.RatLiver
Correa 2015 Critical Care Horizon2015CorrĂȘa TD, Jakob SM, Takala J (2015) Mitochondrial function in sepsis. Critical Care Horizon 1:31-41 .PigLiver
Weidinger 2015 Antioxid Redox Signal2015Weidinger A, MĂŒllebner A, Paier-Pourani J, Banerjee A*, Miller I, Lauterböck L, Duvigneau JC, Skulachev VP, Redl H, Kozlov AV (2015) Vicious inducible nitric oxide synthase-mitochondrial reactive oxygen species cycle accelerates inflammatory response and causes liver injury in rats. Antioxid Redox Signal 22:572-86.RatLiver
Den Besten 2015 Diabetes2015den Besten G, Bleeker A, Gerding A, van Eunen K, Havinga R, van Dijk TH, Oosterveer MH, Jonker JW, Groen AK, Reijngoud DJ, Bakker BM (2015) Short-chain fatty acids protect against high-fat diet-induced obesity via a PPARÎł-dependent switch from lipogenesis to fat oxidation. Diabetes 64:2398-408.MouseLiver
De Andrade 2015 Exp Cell Res2015de Andrade DC, de Carvalho SN, Pinheiro D, Thole AA, Moura AS, de Carvalho L, Cortez EA (2015) Bone marrow mononuclear cell transplantation improves mitochondrial bioenergetics in the liver of cholestatic rats. Exp Cell Res 336:15-22.RatLiver
Sobotka 2015 Physiol Res2015Sobotka O, Drahota Z, Kučera O, Endlicher R, RauchovĂĄ H, ČervinkovĂĄ Z (2015) The effect of α-tocopheryl succinate on succinate respiration in rat liver mitochondria. Physiol Res 64 Suppl 5:S609-15.RatLiver
Williams 2015 J Biol Chem2015Williams AS, Kang L, Zheng J, Grueter CA, Bracy DP, James FD, Pozzi A, Wasserman DH (2015) Integrin α1-null mice exhibit improved fatty liver when fed a high fat diet despite severe hepatic insulin resistance. J Biol Chem 290:6546-57.MouseLiver
Other cell lines
Agil 2015 J Pineal Res2015Agil A, El-Hammadi M, Jiménez-Aranda A, Tassi M, Abdo W, Fernåndez-Våzquez G, Reiter RJ (2015) Melatonin reduces hepatic mitochondrial dysfunction in diabetic obese rats. J Pineal Res 59:70-9.RatLiver
Moore 2015 PhD Thesis2015Moore D (2015) Biostabilization of lipid bilayers: dealing with water stress in embryos of Artemia franciscana. PhD Thesis 1-111.RatLiver
Warne 2015 J Biol Chem2015Warne J, Pryce G, Hill JM, Shi X, LennerÄs F, Puentes F, Kip M, Hilditch L, Walker P, Simone MI, Chan AWE, Towers GJ, Coker AR, Duchen MR, Szabadkai G, Baker D, Selwood DL (2015) Selective inhibition of the mitochondrial permeability transition pore protects against neuro-degeneration in experimental multiple sclerosis. J Biol Chem 291:4356-73.MouseLiver
Drechsler 2015 Intensive Care Medicine Experimental2015Drechsler S, Weixelbaumer KM, Weidinger A, Raeven P, Khadem A, Redl H, van Griensven M, Bahrami S, Remick D, Kozlov A, Osuchowski MF (2015) Why do they die? Comparison of selected aspects of organ injury and dysfunction in mice surviving and dying in acute abdominal sepsis. Intensive Care Medicine Experimental 3:12.MouseLiver
Kidney
Elustondo 2014 Biochim Biophys Acta2014Elustondo PA, Negoda A, Kane CL, Kane DA, Pavlov EV (2014) Spermine selectively inhibits high-conductance, but not low-conductance calcium-induced permeability transition pore. Biochim Biophys Acta 1847:231–40.RatLiver
Kucera 2014 Oxid Med Cell Longev2014Kučera O, Endlicher R, Rouơar T, Lotková H, Garnol T, Drahota Z, Cervinková Z (2014) The effect of tert-butyl hydroperoxide-induced oxidative stress on lean and steatotic rat hepatocytes in vitro. Oxid Med Cell Longev 2014:752506.RatLiver
Other cell lines
Kiss 2014 FASEB J2014Kiss G, Konrad C, Pour-Ghaz I, Mansour JJ, NĂ©meth B, Starkov AA, Adam-Vizi V, Chinopoulos C (2014) Diaphorases provide NAD+ in anoxia. FASEB J 28:1682-97.MouseLiver
Takahashi 2014 Exp Gerontol2014Takahashi K, Noda Y, Ohsawa I, Shirasawa T, Takahashi M (2014) Extended lifespan, reduced body size and leg skeletal muscle mass, and decreased mitochondrial function in clk-1 transgenic mice. Exp Gerontol 58:146-53.MouseSkeletal muscle
Liver
Brandt 2014 Chem Biol Interact2014Brandt AP, do Rocio Andrade Pires A, Rocha ME, Noleto GR, Acco A, de Souza CE, Echevarria A, Dos Santos Canuto AV, Cadena SM (2014) Sydnone SYD-1 affects the metabolic functions of isolated rat hepatocytes. Chem Biol Interact 218C:107-14.RatLiver
Davoudi 2014 PhD Thesis2014Davoudi M (2014) Effect of experimental complex III deficiency on respiratory chain assembly and function. PhD Thesis 1-65.MouseLiver
Hasenour 2014 J Biol Chem2014Hasenour CM, Ridley DE, Hughey CC, James FD, Donahue EP, Shearer J, Viollet B, Foretz M, Wasserman DH (2014) 5-Aminoimidazole-4-carboxamide-1-ÎČ-D-ribofuranoside (AICAR) effect on glucose production, but not energy metabolism, is independent of hepatic AMPK in vivo. J Biol Chem 289:5950-9.MouseLiver
Scandroglio 2014 Free Radic Res2014Scandroglio F, Tortora V, Radi R, Castro L (2014) Metabolic control analysis of mitochondrial aconitase: influence over respiration and mitochondrial superoxide and hydrogen peroxide production. Free Radic Res 48:684-93.RatHeart
Nervous system
Liver
Kidney
Koenemann 2014 Dissertation2014Koenemann B (2014) Einfluss der HyperglykÀmie auf die mitochondriale Atmung von Leberzellen septischer MÀuse mit und ohne Imeglimin. PhD Thesis 1-61.MouseLiver
Hall 2014 Biochim Biophys Acta2014Hall A, Parhamifar L, Lange MK, Meyle KD, Sanderhoff M, Andersen H, Roursgaard M, Larsen AK, Jensen PB, Christensen C, Bartek J, Moghimi SM (2014) Polyethylenimine architecture-dependent metabolic imprints and perturbation of cellular redox homeostasis. Biochim Biophys Acta 1847:328-42.MouseLiver
Boutant 2014 Mol Metab2014Boutant M, Joffraud M, Kulkarni SS, Garcia-Casarrubios E, Garcia-Roves PM, Ratajczak J, Fernandez-Marcos PJ, Valverde AM, Serrano M, Canto C (2014) SIRT1 enhances glucose tolerance by potentiating brown adipose tissue function. Mol Metab 4:118-31.MouseSkeletal muscle
Liver
Fat
Felser 2014 Toxicology I2014Felser A, Stoller A, Morand R, Schnell D, Donzelli M, Terracciano L, Bouitbir J, KrĂ€henbĂŒhl S (2014) Hepatic toxicity of dronedarone in mice: role of mitochondrial ÎČ-oxidation. Toxicology 323:1-9.MouseLiver
Stokich 2014 Cryobiology2014Stokich B, Osgood Q, Grimm D, Moorthy S, Chakraborty N, Menze MA (2014) Cryopreservation of hepatocyte (HepG2) cell monolayers: Impact of trehalose. Cryobiology 69:281-90.HumanLiver
Jelenik 2014 Diabetes2014Jelenik T, SĂ©quaris G, Kaul K, Ouwens DM, Phielix E, Kotzka J, Knebel B, Weiß J, Reinbeck AL, Janke L, Nowotny P, Partke HJ, Zhang D, Shulman GI, Szendroedi J, Roden M (2014) Tissue-specific differences in the development of insulin resistance in a mouse model for type 1 diabetes. Diabetes 63:3856-67.MouseSkeletal muscle
Liver
Davoudi 2014 PLoS One2014Davoudi M, Kotarsky H, Hansson E, Fellman V (2014) Complex I function and supercomplex formation are preserved in liver mitochondria despite progressive Complex III deficiency. PLoS One 9:e86767.MouseLiver
Felser 2014 Toxicology II2014Felser A, Lindinger PW, Schnell D, Kratschmar DV, Odermatt A, Mies S, Jenö P, KrĂ€henbĂŒhl S (2014) Hepatocellular toxicity of benzbromarone: effects on mitochondrial function and structure. Toxicology 324:136-46.HumanLiver
Other cell lines
Garnol 2014 Physiol Res2014Garnol T, Endlicher R, Kučera O, Drahota Z, Cervinková Z (2014) Impairment of mitochondrial function of rat hepatocytes by high fat diet and oxidative stress. Physiol Res 63:271-4.RatLiver
Cahova 2014 Appl Physiol Nutr Metab2014Cahova M, Chrastina P, Hansikova H, Drahota Z, Trnovska J, Skop V, Spacilova J, Malinska HOliyarnyk O, Papackova Z, Palenickova E,Kazdova L (2014) Carnitine supplementation alleviates lipid metabolism derangements and protects against oxidative stress in non-obese hereditary hypertriglyceridemic rats. Appl Physiol Nutr Metab 40:280-91.RatLiver
Ryu 2014 Cell Metab2014Ryu D, Jo YS, Lo Sasso G, Stein S, Zhang H, Perino A, Lee JU, Zeviani M, Romand R, Hottiger MO, Schoonjans K, Auwerx J (2014) A SIRT7-dependent acetylation switch of GABPÎČ1 controls mitochondrial function. Cell Metab 20:856-69.MouseHeart
Nervous system
Liver
Lung;gill
Stenberg 2014 PLoS One2014Stenberg TA, Kildal AB, Sanden E, How OJ, Hagve M, Ytrehus K, Larsen TS, Myrmel T (2014) The acute phase of experimental cardiogenic shock is counteracted by microcirculatory and mitochondrial adaptations. PLoS One 9:e105213.PigHeart
Liver
Kidney
Dogan 2014 Cell Metab2014Dogan SA, Pujol C, Maiti P, Kukat A, Wang S, Hermans S, Senft K, Wibom R, Rugarli EI, Trifunovic A (2014) Tissue-specific loss of DARS2 activates stress responses independently of respiratory chain deficiency in the heart. Cell Metab 19:458-69.MouseHeart
Skeletal muscle
Liver
Chu 2014 PLoS One2014Chu MJ, Hickey AJ, Tagaloa S, Zhang L, Dare AJ, MacDonald JR, Yeong ML, Bartlett AS, Phillips AR (2014) Ob/ob mouse livers show decreased oxidative phosphorylation efficiencies and anaerobic capacities after cold ischemia. PLoS One 9:e100609.MouseLiver
Fletcher 2014 Med Sci Sports Exerc2014Fletcher JA, Meers GM, Linden MA, Kearney ML, Morris EM, Thyfault JP, Rector RS (2014) Impact of various exercise modalities on hepatic mitochondrial function. Med Sci Sports Exerc 46:1089-97.RatLiver
Garratt 2014 Proc Natl Acad Sci U S A2014Garratt M, Pichaud N, Glaros EN, Kee AJ, Brooks RC (2014) Superoxide dismutase deficiency impairs olfactory sexual signaling and alters bioenergetic function in mice. Proc Natl Acad Sci U S A 111:8119-24.MouseLiver
Drahota 2014 Physiol Res2014Drahota Z, Palenickova E, Endlicher R, Milerova M, Brejchova J, Vosahlikova M, Svoboda P, Kazdova L, Kalous M, Cervinkova Z, Cahova M (2014) Biguanides inhibit Complex I, II and IV of rat liver mitochondria and modify their functional properties. Physiol Res 63:1-11.RatLiver
Gjessing 2014 Thesis University of Tromso2014Gjessing PF (2014) Postoperative insulin resistance and the metabolic and cellular responses to single-dose preoperative oral carbohydrate supplementation. Thesis University of Tromso 102 pp.PigSkeletal muscle
Liver
Correa 2014 Crit Care Med2014CorrĂȘa TD, Jeger V, Pereira AJ, Takala J, Djafarzadeh S, Jakob SM (2014) Angiotensin II in septic shock: effects on tissue perfusion, organ function, and mitochondrial respiration in a porcine model of fecal peritonitis. Crit Care Med 42:e550-9.PigHeart
Liver
Kidney
Doerrier 2014 Life Sci2014Doerrier C, García JA, Volt H, Díaz-Casado ME, Lima-Cabello E, Ortiz F, Luna-Sånchez M, Escames G, López LC, Acuña-Castroviejo D (2014) Identification of mitochondrial deficits and melatonin targets in liver of septic mice by high-resolution respirometry. Life Sci 121:158-65.MouseLiver
Correa 2013 Crit Care2013CorrĂȘa TD, Vuda M, Takala J, Djafarzadeh S, Silva E, Jakob SM (2013) Increasing mean arterial blood pressure in sepsis: effects on fluid balance, vasopressor load and renal function. Crit Care 17:R21.PigSkeletal muscle
Liver
Jeger 2013 Abstracts of ESICM LIVES 20132013Jeger V, Steinmann M, Takala J, Jakob SM, Djafarzadeh S (2013) TLR-2-induced mitochondrial dysfunction in cultured human hepatocytes. Abstracts of ESICM LIVES 2013HumanLiver
Hall 2013 Biochim Biophys Acta2013Hall A, Larsen AK, Parhamifar L, Meyle KD, Wu LP, Moghimi SM (2013) High-resolution respirometry analysis of polyethylenimine-mediated mitochondrial energy crisis and cellular stress: Mitochondrial proton leak and inhibition of the electron transport system. Biochim Biophys Acta 1827:1213-25.MouseLiver
Other cell lines
Brown 2013 J Exp Biol2013Brown JC, Chung DJ, Cooper AN, Staples JF (2013) Regulation of succinate-fueled mitochondrial respiration in liver and skeletal muscle of hibernating thirteen-lined ground squirrels. J Exp Biol 216:1736-43.Other mammalsSkeletal muscle
Liver
Ghozlan 2013 Thesis University of Calgary - Canada2013Ghozlan M (2013) The effect of myostatin on glucose metabolism and insulin sensitivity. Thesis University of Calgary - Canada 104pp.MouseSkeletal muscle
Liver
Other cell lines
Karamercan 2013 Shock2013Karamercan MA, Weiss SL, Villarroel JP, Guan Y, Werlin E, Figueredo R, Becker LB, Sims C (2013) Can peripheral blood mononuclear cells be used as a proxy for mitochondrial dysfunction in vital organs during hemorrhagic shock and resuscitation? Shock 40:476-84.RatHeart
Liver
Kidney
Blood cells
Lymphocyte
Strobel 2013 PLoS One2013Strobel A, Graeve M, Poertner HO, Mark FC (2013) Mitochondrial acclimation capacities to ocean warming and acidification are limited in the antarctic nototheniid fish, Notothenia rossii and Lepidonotothen squamifrons. PLoS One 8:e68865.FishesLiver
Gispert 2013 Hum Mol Genet2013Gispert S, Parganlija D, Klinkenberg M, Dröse S, Wittig I, Mittelbronn M, Grzmil P, Koob S, Hamann A, Walter M, BĂŒchel F, Adler T, HrabĂ© de Angelis M, Busch DH, Zell A, Reichert AS, Brandt U, Osiewacz HD, Jendrach M, Auburger G (2013) Loss of mitochondrial peptidase Clpp leads to infertility, hearing loss plus growth retardation via accumulation of CLPX, mtDNA and inflammatory factors. Hum Mol Genet 22:4871-87.MouseHeart
Nervous system
Liver
Genital
Astin 2013 Sci Rep2013Astin R, Bentham R, Djafarzadeh S, Horscroft JA, Kuc RE, Leung PS, Skipworth JR, Vicencio JM, Davenport AP, Murray AJ, Takala J, Jakob SM, Montgomery H, Szabadkai G (2013) No evidence for a local renin-angiotensin system in liver mitochondria. Sci Rep 3:2467.RatLiver
Petiz 2013 Thesis Universidade Federal do Parana - Brazil2013Petiz LL (2013) Efeitos da N-N’-difenil-4-metoxi-benzamidina sobre parĂąmetros do metabolismo energĂ©tico em mitocĂŽndrias e hepatĂłcitos. Thesis Universidade Federal do Parana - Brazil 91pp.Liver
Chu 2013 PLoS One2013Chu MJ, Phillips AR, Hosking AW, Macdonald JR, Bartlett AS, Hickey AJ (2013) Hepatic mitochondrial function analysis using needle liver biopsy samples. PLoS One 8:e79097.Human
Rat
Liver
Van Eunen 2013 PLoS Comput Biol2013van Eunen K, Simons SM, Gerding A, Bleeker A, den Besten G, Touw CM, Houten SM, Groen BK, Krab K, Reijngoud DJ, Bakker BM (2013) Biochemical competition makes fatty-acid ÎČ-oxidation vulnerable to substrate overload. PLoS Comput Biol 9:e1003186.RatLiver
Holmstroem 2013 Metabolism2013Holmström MH, Tom RZ, Björnholm M, Garcia-Roves PM, Zierath JR (2013) Effect of leptin treatment on mitochondrial function in obese leptin-deficient ob/ob mice. Metabolism 62:1258-67.MouseSkeletal muscle
Liver
Pichaud 2013 J Exp Biol2013Pichaud N, Garratt M, Ballard JWO, Brooks RC (2013) Physiological adaptations to reproduction II. Mitochondrial adjustments in livers of lactating mice. J Exp Biol 216:2889-95.MouseLiver
Wang 2013 Hum Mol Genet2013Wang Y, Hekimi S (2013) Mitochondrial respiration without ubiquinone biosynthesis. Hum Mol Genet 22:4768-83.MouseLiver
Camporez 2013 Endocrinology2013Camporez JP, Jornayvaz FR, Petersen M, Pesta D, Guigni BA, Serr J, Zhang D, Kahn M, Samuel VT, Jurczak MJ, Shulman GI (2013) Cellular mechanisms by which FGF21 improves insulin sensitivity in male mice. Endocrinology 154:3099-109.MouseSkeletal muscle
Liver
Fat
Jelenik 2013 Antioxid Redox Signal2013Jelenik T, Roden M (2013) Mitochondrial plasticity in obesity and diabetes mellitus. Antioxid Redox Signal 19:258-68.Skeletal muscle
Liver
Felser 2013 Toxicol Sci2013Felser A, Blum K, Lindinger PW, Bouitbir J, Kraehenbuehl S (2013) Mechanisms of hepatocellular toxicity associated with dronedarone - a comparison to amiodarone. Toxicol Sci 131:480-90.Human
Rat
Liver
Segalés 2013 Am J Physiol Endocrinol Metab2013Segalés J, Paz JC, Hernåndez-Alvarez MI, Sala D, Muñoz JP, Noguera E, Pich S, Palacín M, Enríquez JA, Zorzano A (2013) A form of mitofusin 2 (Mfn2) lacking the transmembrane domains and the COOH-terminal end stimulates metabolism in muscle and liver cells. Am J Physiol Endocrinol Metab 305:1208-21.MouseSkeletal muscle
Liver
Other cell lines
Hernandez-Alvarez 2013 Antioxid Redox Signal2013Hernåndez-Alvarez MI, Paz JC, Sebastiån D, Muñoz JP, Liesa M, Segalés J, Palacín M, Zorzano A (2013) Glucocorticoid modulation of mitochondrial function in hepatoma cells requires the mitochondrial fission protein Drp1. Antioxid Redox Signal 19:366-78.RatLiver
Other cell lines
Kucera 2012 J Gastroenterol Hepatol2012Kucera O, Rousar T, Stankova P, Hanackova L, Lotkova H, Podhola M, Cervinkova Z (2012) Susceptibility of rat non-alcoholic fatty liver to the acute toxic effect of acetaminophen. J Gastroenterol Hepatol 27:323-30.RatLiver
Jung 2012 J Med Food2012Jung HY, Lee AN, Song TJ, An HS, Kim YH, Kim KD, Kim IB, Kim KS, Han BS, Kim CH, Kim KS, Kim JB (2012) Korean mistletoe (Viscum album coloratum) extract improves endurance capacity in mice by stimulating mitochondrial activity. J Med Food 15:621-8.MouseLiver
Kidney
Holmstroem 2012 Am J Physiol Endocrinol Metab2012Holmstroem MH, Iglesias-Gutierrez E, Zierath JR, Garcia-Roves PM (2012) Tissue-specific control of mitochondrial respiration in obesity-related insulin resistance and diabetes. Am J Physiol Endocrinol Metab 302:E731-9.MouseSkeletal muscle
Liver
Strobel 2012 Front Zool2012Strobel A, Bennecke S, Leo E, Mintenbeck K, Pörtner HO, Mark FC (2012) Metabolic shifts in the Antarctic fish Notothenia rossii in response to rising temperature and PCO2. Front Zool 9:28.FishesLiver
Moon 2012 J Korean Med Sci2012Moon MK, Kim MJ, Jung IK, Koo YD, Ann HY, Lee KJ, Kim SH, Yoon YC, Cho BJ, Park KS, Jang HC, Park YJ (2012) Bisphenol A impairs mitochondrial function in the liver at doses below the no observed adverse effect level. J Korean Med Sci 27:644-52.MouseLiver
Sebastian 2012 Proc Natl Acad Sci U S A2012SebastiĂĄn D, HernĂĄndez-Alvarez MI, SegalĂ©s J, Sorianello E, Muñoz JP, Sala D, Waget A, Liesa M, Paz JC, Gopalacharyulu P, OreĆĄič M, Pich S, Burcelin R, PalacĂ­n M, Zorzano A (2012) Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis. Proc Natl Acad Sci U S A 109:5523-8.Human
Mouse
Skeletal muscle
Liver
Rodrigues-Ferreira 2012 J Bioenerg Biomembr2012Rodrigues-Ferreira C, Pereira da Silva AP, Galina A (2012) Effect of the antitumoral alkylating agent 3-bromopyruvate on mitochondrial respiration: role of mitochondrially bound hexokinase. J Bioenerg Biomembr 44:39-49.Human
Mouse
Nervous system
Liver
Other cell lines
Moon 2012 J Biol Chem2012Moon SH, Jenkins CM, Kiebish MA, Sims HF, Mancuso DJ, Gross RW (2012) Genetic ablation of calcium-independent phospholipase A2Îł (iPLA2Îł) attenuates calcium-induced opening of the mitochondrial permeability transition pore and resultant cytochrome c release. J Biol Chem 287:29837-50.MouseLiver
Sorochkina 2012 PLoS One2012Sorochkina AI, Plotnikov EY, Rokitskaya TI, Kovalchuk SI, Kotova EA, Sychev SV, Zorov DB, Antonenko YN (2012) N-terminally glutamate-substituted analogue of gramicidin A as protonophore and selective mitochondrial uncoupler. PLoS One 7:e41919.RatLiver
Thiede 2012 Biochim Biophys Acta2012Thiede A, Gellerich FN, Schönfeld P, Siemen D (2012) Complex effects of 17ÎČ-estradiol on mitochondrial function. Biochim Biophys Acta 1817:1747-53.RatNervous system
Liver
Nin 2012 J Biol Chem2012Nin V, Escande C, Chini CC, Giri S, Camacho-Pereira J, Matalonga J, Lou Z, Chini EN (2012) Role of deleted in breast cancer 1 (DBC1) protein in SIRT1 deacetylase activation induced by protein kinase A and AMP-activated protein kinase. J Biol Chem 287:23489-501.Liver
Freyer 2012 Nat Genet2012Freyer C, Cree LM, Mourier A, Stewart JB, Koolmeister C, Milenkovic D, Wai T, Floros VI, Hagström E, Chatzidaki EE, Wiesner RJ, Samuels DC, Larsson NG, Chinnery PF (2012) Variation in germline mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission. Nat Genet 44:1282-5.MouseHeart
Liver
Djafarzadeh 2012 PLoS One2012Djafarzadeh S, Vuda M, Takala J, Jakob SM (2012) Effect of remifentanil on mitochondrial oxygen consumption of cultured human hepatocytes. PLoS One 7:e45195.HumanLiver
Correa 2012 Crit Care Med2012CorrĂȘa TD, Vuda M, Blaser AR, Takala J, Djafarzadeh S, DĂŒnser MW, Silva E, Lensch M, Wilkens L, Jakob SM (2012) Effect of treatment delay on disease severity and need for resuscitation in porcine fecal peritonitis. Crit Care Med 40:2841-9.PigHeart
Skeletal muscle
Nervous system
Liver
Joergensen 2012 Am J Physiol Endocrinol Metab2012JĂžrgensen W, Jelnes P, Rud KA, Hansen LL, Grunnet N, Quistorff B (2012) Progression of type 2 diabetes in GK rats affects muscle and liver mitochondria differently: pronounced reduction of Complex II flux is observed in liver only. Am J Physiol Endocrinol Metab 303:E515-23.RatSkeletal muscle
Liver
Domenis 2012 Int J Mol Sci2012Domenis R, Bisetto E, Rossi D, Comelli M, Mavelli I (2012) Glucose-modulated mitochondria adaptation in tumor cells: a focus on ATP synthase and inhibitor factor 1. Int J Mol Sci 13:1933-50.HumanLiver
Drahota 2012 Physiol Res2012Drahota Z, Milerová M, Endlicher R, Rychtrmoc D, Červinková Z, Oơt'ádal B (2012) Developmental changes of the sensitivity of cardiac and liver mitochondrial permeability transition pore to calcium load and oxidative stress. Physiol Res 61:S165-72.RatHeart
Liver
El-Bacha 2012 Int J Biochem Cell Biol2012El-Bacha T, Da Poian AT (2012) Virus-induced changes in mitochondrial bioenergetics as potential targets for therapy. Int J Biochem Cell Biol 45:41-6.Human
Mouse
Nervous system
Liver
Fibroblast
Ramirez-Torres 2012 J Proteomics2012Ramirez-Torres A, Barcelo-Batllori S, Fernandez-Vizarra E, Navarro MA, Arnal C, Guillen N, Acin S, Osada J (2012) Proteomics and gene expression analyses of mitochondria from squalene-treated apoE-deficient mice identify short-chain specific acyl-CoA dehydrogenase changes associated with fatty liver amelioration. J Proteomics 75:2563-75.MouseLiver
Brown 2012 Am J Physiol Regul Integr Comp Physiol2012Brown JC, Chung DJ, Belgrave KR, Staples JF (2012) Mitochondrial metabolic suppression and reactive oxygen species production in liver and skeletal muscle of hibernating thirteen-lined ground squirrels. Am J Physiol Regul Integr Comp Physiol 302:R15-28.Other mammalsSkeletal muscle
Liver
Vuda 2012 Innate Immun2012Vuda M, Brander L, Schröder R, Jakob SM, Takala J, Djafarzadeh S (2012) Effects of catecholamines on hepatic and skeletal muscle mitochondrial respiration after prolonged exposure to faecal peritonitis in pigs. Innate Immun 18:217-30.PigSkeletal muscle
Liver
Aoun 2012 Br J Nutr2012Aoun M, Feillet-Coudray C, Fouret G, Chabi B, Crouzier D, Ferreri C, Chatgilialoglu C, Wrutniak-Cabello C, Cristol JP, Carbonneau MA, Coudray C (2012) Rat liver mitochondrial membrane characteristics and mitochondrial functions are more profoundly altered by dietary lipid quantity than by dietary lipid quality: effect of different nutritional lipid patterns. Br J Nutr 107:647-59.RatLiver
MiPNet08.12 IOC222011-12-11
O2k-Protocols
NO effect on mitochondrial oxygen kinetics at low oxygen. O2k workshop Report.
RatLiver
Quarato 2011 Biochim Biophys Acta2011Quarato G, Piccoli C, Scrima R, Capitanio N (2011) Variation of flux control coefficient of cytochrome c oxidase and of the other respiratory chain complexes at different values of protonmotive force occurs by a threshold mechanism. Biochim Biophys Acta 1807: 1114-1124.Human
Mouse
Liver
Fibroblast
Phung 2011 J Food Science2011Phung VT, Saelid E, Egelandsdal B, Volden J, Slinde E (2011) Oxygen consumption rate of permeabilized cells and isolated mitochondria from pork M. masseter and liver examined fresh and after freeze-thawing at different pH values. J Food Science 76:C929-36.PigLiver
Dungel 2011 J Biochem Mol Toxicol2011Dungel P, Haindl S, Behling T, Mayer B, Redl H, Kozlov AV (2011) Neither nitrite nor nitric oxide mediate toxic effects of nitroglycerin on mitochondria. J Biochem Mol Toxicol 25:297-302.RatLiver
Kucera 2011 Physiol Res2011Kučera O, Garnol T, Lotková H, Staƈková P, Mazurová Y, Hroch M, Bolehovská R, Rouơar T, Červinková Z (2011) The effect of rat strain, diet composition and feeding period on the development of a nutritional model of non-alcoholic fatty liver disease in rats. Physiol Res 60:317-28.RatLiver
Palenickova 2011 Physiol Res2011Palenickova E, Cahova M, Drahota Z, Kazdova L, Kalous M (2011) Inhibitory effect of metformin on oxidation of NADH-dependent substrates in rat liver homogenate. Physiol Res 60:835-9.RatLiver
Leveen 2011 Hepatology2011Levéen P, Kotarsky H, Mörgelin M, Karikoski R, Elmér E, Fellman V (2011) The GRACILE mutation introduced into Bcs1l causes postnatal Complex III deficiency: a viable mouse model for mitochondrial hepatopathy. Hepatology 53:437-47.MouseHeart
Liver
Kidney
Kelly 2011 Mitochondrion2011Kelly OM, McNamara YM, Manzke LH, Meegan MJ, Porter RK (2011) The preservation of in vivo phosphorylated and activated uncoupling protein 3 (UCP3) in isolated skeletal muscle mitochondria following administration of 3,4-methylenedioxymethamphetamine (MDMA aka ecstasy) to rats/mice. Mitochondrion. 12:110-19.Mouse
Rat
Skeletal muscle
Liver
Kucera 2011 Int J Exp Pathol2011Kučera O, Lotková H, Staƈková P, Podhola M, Rouơar T, Mezera V, Cervinková Z (2011) Is rat liver affected by non-alcoholic steatosis more susceptible to the acute toxic effect of thioacetamide?. Int J Exp Pathol 92:281-9.RatLiver
Djafarzadeh 2011 Mitochondrion2011Djafarzadeh S, Vuda M, Takala J, Ochs M, Jakob SM (2011) Toll-like receptor-3-induced mitochondrial dysfunction in cultured human hepatocytes. Mitochondrion 11:83-8.HumanLiver
Pecinova 2011 Mitochondrion2011Pecinova A, Drahota Z, Nuskova H, Pecina P, Houstek J (2011) Evaluation of basic mitochondrial functions using rat tissue homogenates. Mitochondrion 11:722-8.RatHeart
Nervous system
Liver
Kidney
Flachs 2011 Diabetologia2011Flachs P, RĂŒhl R, Hensler M, Janovska P, Zouhar P, Kus V, Macek Jilkova Z, Papp E, Kuda O, Svobodova M, Rossmeisl M, Tsenov G, Mohamed-Ali V, Kopecky J (2011) Synergistic induction of lipid catabolism and anti-inflammatory lipids in white fat of dietary obese mice in response to calorie restriction and n-3 fatty acids. Diabetologia 54:2626-38.MouseSkeletal muscle
Liver
Fat
Mittal 2011 HPB (Oxford)2011Mittal A, Hickey AJ, Chai CC, Loveday BP, Thompson N, Dare A, Delahunt B, Cooper GJ, Windsor JA, Phillips AR (2011) Early organ-specific mitochondrial dysfunction of jejunum and lung found in rats with experimental acute pancreatitis. HPB (Oxford) 13:332-41.RatHeart
Liver
Kidney
Islet cell;pancreas;thymus
Antonenko 2011 J Biol Chem2011Antonenko YN, Avetisyan AV, Cherepanov DA, Knorre DA, Korshunova GA, Markova OV, Ojovan SM, Perevoshchikova IV, Pustovidko AV, Rokitskaya TI, Severina II, Simonyan RA, Smirnova EA, Sobko AA, Sumbatyan NV, Severin FF, Skulachev VP (2011) Derivatives of rhodamine 19 as mild mitochondria-targeted cationic uncouplers. J Biol Chem 286:17831-40.Rat
Fungi
Liver
Domenis 2011 J Bioenerg Biomembr2011Domenis R, Comelli M, Bisetto E, Mavelli I (2011) Mitochondrial bioenergetic profile and responses to metabolic inhibition in human hepatocarcinoma cell lines with distinct differentiation characteristics. J Bioenerg Biomembr 43: 493-505.HumanLiver
Zangl 2011 Thesis UniversitĂ€t Ulm - Germany2011Zangl Q (2011) Funktion hepatischer Mitochondrien nach IschĂ€mie-Reperfusion und vorheriger Behandlung mit Schwefelwasserstoff im Großtierversuch. Thesis UniversitĂ€t Ulm - Germany 69pp.PigLiver
Brown 2011 Am J Physiol Regul Integr Comp Physiol2011Brown JC, Chung DJ, Belgrave KR, Staples JF (2011) Mitochondrial metabolic suppression and reactive oxygen species production in liver and skeletal muscle of hibernating thirteen-lined ground squirrels. Am J Physiol Regul Integr Comp Physiol 302:15-28.Other mammalsSkeletal muscle
Liver
Lagoutte 2010 Biochim Biophys Acta2010Lagoutte E, Mimoun S, Andriamihaja M, Chaumontet C, Blachier F, Bouillaud F (2010) Oxidation of hydrogen sulfide remains a priority in mammalian cells and causes reverse electron transfer in colonocytes. Biochim Biophys Acta 1797:1500-11.MouseHeart
Nervous system
Liver
Kidney
CHO
Fornuskova 2010 Thesis2010FornĆŻskovĂĄ D (2010) Biochemical and molecular studies of cytochrome c oxidase and ATP synthase deficiencies. PhD Thesis p93.HumanHeart
Skeletal muscle
Nervous system
Liver
HEK
Fibroblast
Stankova 2010 Toxicol In Vitro2010Staƈková P, Kučera O, Lotková H, Rouơar T, Endlicher R, Cervinková Z (2010) The toxic effect of thioacetamide on rat liver in vitro. Toxicol In Vitro 24:2097-2103.Liver
Kozlov 2010 Inflammation2010Kozlov AV, van Griensven M, Haindl S, Kehrer I, Duvigneau JC, Hartl RT, Ebel T, Jafarmadar M, Calzia E, Gnaiger E, Redl H, Radermacher P, Bahrami Sl (2010) Peritoneal inflammation in pigs is associated with early mitochondrial dysfunction in liver and kidney. Inflammation 33:295-305.PigLiver
Kidney
Milaeva 2010 Bioinorg Chem Appl2010Milaeva ER, Filimonova SI, Meleshonkova NN, Dubova LG, Shevtsova EF, Bachurin SO, Zefirov NS (2010) Antioxidative activity of ferrocenes bearing 2,6-di-tert-butylphenol moieties. Bioinorg Chem Appl 165482. EpubRatNervous system
Liver
Parvez 2010 Biochim Biophys Acta2010Parvez S, Winkler-Stuck K, Hertel S, Schoenfeld P, Siemen D (2010) The dopamine-D2-receptor agonist ropinirole dose-dependently blocks the Ca(2+)-triggered permeability transition of mitochondria. Biochim Biophys Acta 1797:1245-50.RatLiver
Rauchova 2011 Horm Metab Res2010RauchovĂĄ H, MrĂĄcek T, NovĂĄk P, VokurkovĂĄ M, Soukup T (2010) Glycerol-3-phosphate dehydrogenase expression and oxygen consumption in liver mitochondria of female and male rats with chronic alteration of thyroid status. Horm Metab Res 43:43-7.RatLiver
Duvigneau 2010 Shock2010Duvigneau JC, Kozlov AV, Zifko C, Postl A, Hartl RT, Miller I, Gille L, Staniek K, Moldzio R, Gregor W, Haindl S, Behling T, Redl H, Bahrami Sl (2010) Reperfusion does not induce oxidative stress but sustained endoplasmic reticulum stress in livers of rats subjected to traumatic/hemorrhagic shock. Shock 33:289-98.RatLiver
Schneider 2010 Gastroenterology2010Schneider M, van Geyte K, Fraisl P, Kiss J, Aragones J, Mazzone M, Mairbaeurl H, Debock K, Ho Jeoung N, Mollenhauer M, Georgiadou M, Bishop T, Roncal C, Sutherland A, Jordan B, Gallez B, Weitz J, Harris RA, Maxwell P, Baes M, Ratcliffe P, Carmeliet P (2010) Loss or silencing of the PHD1 prolyl hydroxylase protects livers of mice against ischemia/referpusion injury. Gastroenterology 138:1143-54.MouseSkeletal muscle
Liver
Kosenko 2010 Biology Bull2010Kosenko EA, Abramova MB, Venediktova NI, Popova II, Kaminskii YG (2010) The drug hypoxen: A new inhibitor of mitochondrial respiration and dehydrogenases. Biology Bull 37:346-50.RatLiver
Mantena 2009 Biochem J2009Mantena SK, Vaughn Jr DP, Andringa KK, Eccleston HB, King AL, Abrams GA, Doeller JE, Kraus DW, Darley-Usmar V, Bailey SM (2009) High fat diet induces dysregulation of hepatic oxygen gradients and mitochondrial function in vivo. Biochem J 417:183–93.MouseLiver
Lotkova 2009 Acta Vet Brno2009Lotková H, Kučera O, Rouơar T, Endlicher R, Kƙiváková P, Garnol T, Červinková Z (2009) Effect of S-adenosylmethionine on Acetaminophen-induced toxic injury of rat hepatocytes in vitro. Acta Vet Brno 78:603-13.RatLiver
Morota 2009 Exp Neurol2009Morota S, MÄnsson R, Hansson Magnus J, Kasuya K, Shimazu M, Hasegawa E, Yanagi S, Omi A, Uchino H, Elmér E (2009) Evaluation of putative inhibitors of mitochondrial permeability transition for brain disorders-specificity vs. toxicity. Exp Neurol 218:353-62.HumanLiver
Kozlov 2009 Biochim Biophys Acta2009Kozlov AV, Duvigneau JC, Miller I, NĂŒrnberger S, Gesslbauer B, Kungl A, Ohlinger W, Hartl RT, Gille L, Staniek K, Gregor W, Haindl S, Redl H (2009) Endotoxin causes functional endoplasmic reticulum failure, possibly mediated by mitochondria. Biochim Biophys Acta 1792:521-30.RatLiver
Plecita-Hlavata 2009 Int J Biochem Cell Biol2009Plecita-Hlavata L, Jezek J, Jezek P (2009) Pro-oxidant mitochondrial matrix-targeted ubiquinone MitoQ10 acts as anti-oxidant at retarded electron transport or proton pumping within Complex I. Int J Biochem Cell Biol 41:1697-707.Rat
Human
Liver
Other cell lines
Kupsch 2009 FEBS J2009Kupsch K, Hertel S, Kreutzmann P, Wolf G, Wallesch CW, Siemen D, Schönfeld P (2009) Impairment of mitochondrial function by minocycline. FEBS J 276:1729–38.RatLiver
Flamment 2009 Am J Physiol Endocrinol Metab2009Flamment M, Gueguen N, Wetterwald C, Simard G, MalthiĂšry Y, Ducluzeau PH (2009) Effects of the cannabinoid CB1 antagonist rimonabant on hepatic mitochondrial function in rats fed a high-fat diet. Am J Physiol Endocrinol Metab 297:E1162-70.RatLiver
Fangue 2009 J Exp Biol2009Fangue NA, Richards JG, Schulte PM (2009) Do mitochondrial properties explain intraspecific variation in thermal tolerance? J Exp Biol 212:514-22.FishesLiver
Endlicher 2009 Physiol Res2009Endlicher R, KrivĂĄkovĂĄ P, RauchovĂĄ H, NĆŻskovĂĄ H, CervinkovĂĄ Z, Drahota Z (2009) Peroxidative damage of mitochondrial respiration is substrate-dependent. Physiol Res 58:685-92.RatLiver
Labieniec 2009 Chem Biol Interact2009Labieniec M, Przygodzki T, CĂĄrsky J, Malinska D, Rysz J, Watala C (2009) Effects of resorcylidene aminoguanidine (RAG) on selected parameters of isolated rat liver mitochondria. Chem Biol Interact 179:280-7.RatLiver
Cervinkova 2009 Arch Toxicol2009CervinkovĂĄ Z, KrivĂĄkovĂĄ P, LĂĄbajovĂĄ A, Rousar T, LotkovĂĄ H, Kucera O, Endlicher R, Cervinka M, Drahota Z (2009) Mechanisms participating in oxidative damage of isolated rat hepatocytes. Arch Toxicol 83:363-72.RatLiver
Moisoi 2009 Cell Death Differ2009Moisoi N, Klupsch K, Fedele V, East P, Sharma S, Renton A, Plun-Favreau H, Edwards RE, Teismann P, Esposti MD, Morrison AD, Wood NW, Downward J, Martins LM (2009) Mitochondrial dysfunction triggered by loss of HtrA2 results in the activation of a brain-specific transcriptional stress response. Cell Death Differ 16:449-64.MouseNervous system
Liver
Ripoli 2009 J Virol2009Ripoli Maria, D'Aprile Annamaria, Quarato Giovanni, Sarasin-Filipowicz Magdalena, Gouttenoire JérÎme, Scrima Rosella, Cela Olga, Boffoli Domenico, Heim Markus H, Moradpour Darius, Capitanio Nazzareno, Piccoli Claudia (2009) Hepatitis C virus-linked mitochondrial dysfunction promotes hypoxia-inducible factor 1α-mediated glycolytic adaptation. J Virol 84:647-60.HumanLiver
Other cell lines
Lim 2009 PlosOne2009Lim S, Ahn SY, Song IC, Chung MH, Jang HC, Park KS, Lee KU, Pak YK, Lee HK (2009) Chronic exposure to the herbicide, atrazine, causes mitochondrial dysfunction and insulin resistance. PLoS One 4:e5186.RatSkeletal muscle
Liver
Dalmonte 2009 J Biol Chem2009Dalmonte ME, Forte E, Genova ML, GiuffrĂš A, Sarti P, Lenaz G (2009) Control of respiration by cytochrome c oxidase in intact cells: role of the membrane potential. J Biol Chem 284:32331-5.Human
Rat
Liver
Schoenfeld 2009 Free Radic Biol Med2009Schönfeld P, Dymkowska D, Wojtczak L (2009) Acyl-CoA-induced generation of reactive oxygen species in mitochondrial preparations is due to the presence of peroxisomes. Free Radic Biol Med 47:503-9.RatLiver
Regueira 2009 Liver Int2009Regueira T, Lepper PM, Brandt S, Ochs M, Vuda M, Takala J, Jakob SM, Djafarzadeh S (2009) Hypoxia inducible factor-1alpha induction by tumour necrosis factor-alpha, but not by toll-like receptor agonists, modulates cellular respiration in cultured human hepatocytes. Liver Int 10:1582-92.HumanLiver
Lopez 2009 J Pineal Res2009López A, García JA, Escames G, Venegas C, Ortiz F, López LC, Acuña-Castroviejo D (2009) Melatonin protects the mitochondria from oxidative damage reducing oxygen consumption, membrane potential, and superoxide anion production. J Pineal Res 46:188-98.MouseLiver
Tahara 2009 Free Radic Biol Med2009Tahara EB, Navarete FD, Kowaltowski AJ (2009) Tissue-, substrate-, and site-specific characteristics of mitochondrial reactive oxygen species generation. Free Radic Biol Med 46:1283-97.RatHeart
Skeletal muscle
Nervous system
Liver
Kidney
Pereira 2009 Biochem J2009Pereira da Silva AP, El-Bacha T, Kyaw N, dos Santos RS, Da Silva WS, Almeida FC, Da Poian AT, Galina A (2009) Inhibition of energy-producing pathways of HepG2 cells by 3-bromopyruvate. Biochem J 417:717-26.HumanLiver
De Cavanagh 2008 Exp Gerontol2008de Cavanagh EM, Flores I, Ferder M, Inserra F, Ferder L (2008) Renin-angiotensin system inhibitors protect against age-related changes in rat liver mitochondrial DNA content and gene expression. Exp Gerontol 43:919-28.RatLiver
Hildebrandt 2008 FEBS J2008Hildebrandt TM, Grieshaber MK (2008) Three enzymatic activities catalyze the oxidation of sulfide to thiosulfate in mammalian and invertebrate mitochondria. FEBS J 275:3352-6.Rat
Annelids
Liver
Regueira 2008 Crit Care Med2008Regueira T, Baenziger B, Djafarzadeh S, Brandt S, Gorrasi J, Takala J, Lepper PM, Jakob SM (2008) Norepinephrine to increase blood pressure in endotoxaemic pigs is associated with improved hepatic mitochondrial respiration. Crit Care Med 12:R88PigLiver
Hansson 2008 Free Radic Biol Med2008Hansson Magnus J, MÄnsson R, Morota S, Uchino H, Kallur T, Sumi T, Ishii N, Shimazu M, Keep MF, Jegorov A, Elmér E (2008) Calcium-induced generation of reactive oxygen species in brain mitochondria is mediated by permeability transition. Free Radic Biol Med 45:284-94.RatNervous system
Liver
Dlaskova 2008 Int J Biochem Cell Biol2008DlaskovĂĄ A, HlavatĂĄ L, Jezek J, Jezek P (2008) Mitochondrial Complex I superoxide production is attenuated by uncoupling. Int J Biochem Cell Biol 40:2098-109.RatLiver
Cervinkova 2008 Physiol Res2008CervinkovĂĄ Z, RauchovĂĄ H, KrivĂĄkovĂĄ P, Drahota Z (2008) Inhibition of palmityl carnitine oxidation in rat liver mitochondria by tert-butyl hydroperoxide. Physiol Res 57:133-6.Liver
Severina 2007 Biochim Biophys Acta2007Severina II, Vyssokikh MY, Pustovidko AV, Simonyan RA, Rokitskaya TI, Skulachev VP (2007) Effects of lipophilic dications on planar bilayer phospholipid membrane and mitochondria. Biochim Biophys Acta 1767:1164-8.RatLiver
Cervinkova 2007 Altern Lab Anim2007Cervinkova Z, Lotkova H, Krivaikova P, Rousar T, Kucera O, Tichy L, Cervinka M, Drahota Z (2007) Evaluation of mitochondrial function in isolated rat hepatocytes and mitochondria during oxidative stress. Altern Lab Anim 35:353-61.RatLiver
Krivakova 2007 Physiol Res2007Krivakova P, Labajova A, Cervinkova Z, Drahota Z (2007) Inhibitory effect of t-butyl hydroperoxide on mitochondrial oxidative phosphorylation in isolated rat hepatocytes. Physiol Res 56:137-40.RatLiver
Miller 2006 FEBS Lett2006Miller I, Gemeiner M, Gesslbauer B, Kungl A, Piskernik C, Haindl S, NĂŒrnberger S, Bahrami Sl, Redl H, Kozlov AV (2006) Proteome analysis of rat liver mitochondria reveals a possible compensatory response to endotoxic shock. FEBS Lett 580:1257-62.RatLiver
... further results
O2k-Publications in the MiPMap

O2k-Publications: Liver - Abstracts

Sort in ascending/descending order by a click on one of the small symbols in squares below.
 ReferenceOrganismTissue;cell
Stankova 2023 MiP2023
Stankova Pavla
Effect of telmisartan on nutritionally induced nonalcoholic steatohepatitis in mice.
MouseLiver
Baglivo 2023 ESCI Prague
Baglivo Eleonora
Baglivo E, Timon-Gomez A, Gnaiger E (2023) The cytochrome c test for respirometric quality control of the integrity of the mitochondrial outer membrane. 57th Annual Scientific Meeting of the European Society for Clinical Investigation.
Human
Bovines
Heart
Liver
HEK
Komlodi 2023 EUROMIT2023 BolognaKomlĂłdi T, Silva FSG, Duarte AI, Mena D, Garcia-Souza LF, Makrecka-Kuka M, Bento G, Grilo LF, Oliveira PJ, Gnaiger E (2023) Off-target effects of etomoxir: inhibition of mitochondrial Complex I and fatty acid oxidation. EUROMIT2023 International Conference on Mitochondrial Pathology.Human
Mouse
Nervous system
Liver
Cecatto 2022 EBEC
Cristiane Cecatto
Cecatto C, Cardoso LHD, Gnaiger E (2022) Mitochondrial calcium uptake capacity is lower than calcium retention capacity in the presence and absence of cyclosporin A. EBEC 2022.
MouseLiver
Cecatto 2022 Abstract Bioblast5.1. «10+5»
Cecatto Cristiane
Cecatto Cristiane, Cardoso LHD, Gnaiger E (2022) Mitochondrial calcium uptake capacity is lower than calcium retention capacity in the presence and absence of cyclosporin A. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001 »Watch the presentation«
MouseLiver
Cardoso 2022 Abstract Bioblast4.3. «10+5»
Luiza Cardoso
Cardoso Luiza HD, Doerrier C, Donnelly C, Komlódi T, Gnaiger E (2022) Redox monitoring and respiration - a new horizon with the NextGen-O2k. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001 »Watch the presentation«
MouseLiver
HEK
Zujovic 2019 MiP2019
Tijana Zujovic
Cell membrane permeabilization: digitonin optimization pitfalls.
Human
Mouse
Skeletal muscle
Liver
Stevanovic 2019 MiPschool Coimbra
MiPsociety
Gestational physical exercise offers prolonged protection to liver mitochondrial function of female offspring against deleterious effects of maternal gestational diabetes.
RatLiver
Tioli 2019 MiP2019
MiPsociety
Involvement of mitochondrial respiratory supercomplexes in anti-bacterial innate immunity.
MouseHeart
Liver
Blood cells
Macrophage-derived
Fuertes-Agudo 2019 MiPschool CoimbraMarina Fuertes Agudo Role of COX-2 in liver and heart mitochondrial function.MouseHeart
Skeletal muscle
Liver
Cardoso 2019 MiP2019
Luiza Cardoso
Effects of glucose concentration in cell culture media on hepatocellular carcinoma HuH7 cells evaluated by high-resolution respirometry.
HumanLiver
Silva 2019 MiPschool Coimbra
Filomena Pereira da Silva Grilo da Silva
Off-target effects of etomoxir on mitochondrial Complex I.
Human
Mouse
Liver
Silva 2019 ESCI2019Silva FSG, Komlodi T, Garcia-Souza LF, Bento G, Doerrier C, Oliveira PJ, Gnaiger E (2019) Can fatty acid oxidation be specifically blocked by the CPT1 inhibitor etomoxir?Human
Mouse
Liver
Lalic 2109 MiP2019
Nebojsa Lalic
Pathophysiology of type 2 diabetes and mitochondrial dysfunction: possible therapeutic implications.
Skeletal muscle
Liver
Krako Jakovljevic 2019 MiP2019
Nina Krako Jakovljevic
Lower insulin sensitivity differently affects mitochondrial coupling in liver and muscle cells.
Human
Mouse
Skeletal muscle
Liver
Goikoetxea-Usandizaga 2019 MiPschool Coimbra
Naroa Goikoetxea Usandizaga
Methylation Controlled J protein (MCJ): A therapeutic target in hepatic ischemia and reperfusion injury.
MouseLiver
Rodriguez-Hernandez 2018 Free Radic Biol MedRodriguez-HernĂĄndez A, StaƈkovĂĄ P, GonzĂĄlez R, De la Rosa AJ, Álamo-Martinez JM, Marin-GĂłmez LM, Sobotka O, Kučera O, Padillo FJ, ČervinkovĂĄ Z, MuntanĂ© J (2018) The alteration of mitochondrial function is associated with the induction of endoplasmic reticulum stress autophagy and apoptosis by Sorafenib in liver cancer cells. Free Radic Biol Med.Liver
Komlodi 2018b EBEC2018Endogenous quinones sustain NADH oxidation by Complex I during anoxia, supporting substrate-level phosphorylation in mouse liver mitochondria.MouseLiver
Kappler 2018 J Lab MedKappler L, Hoene M, Kollipara L, Li J, Hu C, van Törne C, Hauck S, Irmler M, Beckers J, de Angelis MH, Peter A, Xu G, HÀring H, Weigert C, Sickmann A (2018) Systems medicine approach combining Multi-omics and functional analyses in hepatic and skeletal muscle mitochondria of pre-diabetic mice. J Lab Med.MouseSkeletal muscle
Liver
Ravasz 2018 Abstract The evolving concept of mitochondriaVast pools of endogenous quinones sustain NADH oxidation by Complex I during anoxia, supporting substrate-level phosphorylation in mouse liver mitochondria.MouseLiver
Stankova 2018 MiP2018
Pavla Krivakova-Stankova
Impact of western diet on energy metabolism in mouse liver.
MouseLiver
Kovalev 2018 EMBSKovalev A, Sokolova I, Sukhotin A (2018) Allometry of mitochondrial respiration in mussels. EMBS.MolluscsLiver
Islet cell;pancreas;thymus
Jansen 2018 MiPschool Tromso C2
MiPsociety
Dietary and pharmacological treatment of diet-induced obese mice – impact on mitochondrial function.
MouseHeart
Skeletal muscle
Liver
Fat
Meszaros 2018 EBEC2018Tissue- and substrate-specific patterns in the oxygen kinetics of mitochondrial respiration.MouseHeart
Nervous system
Liver
Fischer 2018 MiPschool Tromso E2
Christine Fischer
Analysis of mitochondrial function in iron deficiency anemia and iron overload conditions.
MouseHeart
Nervous system
Liver
Pereira da Silva Grilo da Silva 2018 MiP2018
Filomena Pereira da Silva Grilo da Silva
The unspecific effect of etomoxir on mitochondrial respiration.
Human
Mouse
Nervous system
Liver
Other cell lines
Meszaros 2018 Mt Med HinxtonHigh-resolution mitochondrial oxygen kinetics as diagnostic tool in Complex IV impairments.MouseHeart
Nervous system
Liver
Goncalo Teixeira 2018 MiPschool Tromso C1
MiPsociety
Subchronic in vivo study for the evaluation of hepatic mitochondrial toxicity induced by silver nanoparticles.
RatLiver
Heart
Kidney
Belosludtsev 2018 MiP2018
MiPsociety
Effect of bedaquiline and delamanid on the functions of rat liver mitochondria.
RatLiver
Endlicher 2017 MiP2017
Rene Endlicher
Age-related changes in isolated mitochondria from rat liver.
RatLiver
Scatena 2017 Abstract MITOEAGLE Barcelona
COST Action MITOEAGLE
Mitochondria and cancer stem cells in hepatocarcinoma. An illustrative example of a tangled methodological approach.
Liver
Aasander Frostner 2017 MiP2017
Åsander Frostner Eleonor
Cell-permeable succinate and malonate as research tools. Aasander Frostner_Poster
HumanHeart
Liver
Blood cells
Fibroblast
Kovalcikova 2017 MiP2017
Kovalcikova Jana
Mitochondrial protein TMEM70: key role in the biogenesis of ATP synthase verified in a mouse knockout model.
MouseHeart
Liver
Sobotka 2017 Abstract MITOEAGLE Barcelona
COST Action MITOEAGLE
The effect of 24 weeks of high-fat and high-cholesterol diet on rat liver mitochondria. Sobotka_Presentation
RatLiver
Hoppel 2017 MiP2017
Charles Hoppel
Pathways of mitochondrial fatty acid oxidation. Hoppel_Presentation
RatLiver
Skolik 2017 Abstract IOC122What can we learn from different sugars as substrates for cancer cells?HumanLiver
Meszaros 2017 MiP2017
Andras Meszaros
Mitochondrial oxygen kinetics as a sensitive diagnostic tool to determine apparent cytochrome c oxidase excess capacity.
MouseNervous system
Liver
Kidney
Meszaros 2017 MiPschool Obergurgl
Andras Meszaros
(Very) High-resolution respirometry – a deep dive into oxygen dependence of mitochondrial respiration.
MouseLiver
Nervous system
Kidney
Nedergaard 2017 MiP2017
Jan Nedergaard
Creatine effect in mitochondria from different tissues.
MouseHeart
Liver
Fat
Juhasz 2017 MiPschool Obergurgl
Juhasz L.jpg
Blockade of N-methyl-D-aspartate receptors improves polymicrobial sepsis-evoked mitochondrial dysfunction in rats.
RatLiver
Komlodi 2017 Abstract MITOEAGLE Barcelona
COST Action MitoEAGLE
Succinate dehydrogenase regulation via oxaloacetate in brain mitochondria.
Guinea pig
Mouse
Nervous system
Kidney
Heart
Liver
Sobotka 2017 MiP2017
Ondrej Sobotka
Metabolic changes in rat liver mitochondria during the development of liver steatosis.
RatLiver
Madlala 2016 Abstract MitoFit Science Camp 2016Fructose-induced defects in selected mitochondrial enzymes is detected by respirometry using glutamate&malate but not pyruvate&malate substrates.HumanLiver
Volani 2016 Abstract Mito Xmas Meeting InnsbruckEffects of systemic iron perturbations on mitochondrial activity and on cellular metabolism in vivo.MouseLiver
Calzia 2016 Abstract MitoFit Science Camp 2016Mitochondrial respiration shows tissue- and strain-specific aging in short- and long-lived N. furzeri strains.FishesHeart
Skeletal muscle
Nervous system
Liver
Volani 2016 Abstract MitoFit Science Camp 2016Effects of iron imbalances on mitochondrial activity in mouse liver homogenate and permabilized rat PBMCs.Mouse
Rat
Liver
Blood cells
Lymphocyte
Bird 2016 Abstract IOC115High-resolution respirometry for the diagnosis of mitochondrial disease.HumanSkeletal muscle
Liver
Fibroblast
Buck 2016 Abstract J Neurol Neurosurg PsychiatryB30 Integrated mitochondrial function in human fine-needle muscle biopsies of huntington’s disease mutation carriers and in tissues of HdhQ111 mice.MouseHeart
Skeletal muscle
Nervous system
Liver
Sobotka 2016 Abstract IOC116Sobotka O, Kucera Otto, Stankova P, Endlicher R, Nozickova K, Banni A, Cervinkova Z (2016) Mitochondrial respiration in fatty liver. Mitochondr Physiol Network 21.11RatLiver
Garcia-Souza 2016 Abstract Mito Xmas Meeting InnsbruckAssessment of fatty acid oxidation in mouse brain and liver mitochondria.Nervous system
Liver
Hill 2015 Abstract MiPschool London 2015A novel inhibitor of the mitochondrial permeability transition pore is beneficial in an experimental model of multiple sclerosis.MouseLiver
Sheldon 2015 Abstract MiPschool Greenville 2015eNOS is required to preserve hepatic mitochondrial function in western diet-induced nonalcoholic fatty liver disease.MouseLiver
Weidgang 2015 Abstract MiP2015Mitochondrial respiration in homogenized biopsies from kidney, liver, heart and diaphragm from mice after blunt thoracic trauma and hemorrhagic shock. Effects of a novel hydrogen sulfide donor AP39.MouseHeart
Skeletal muscle
Liver
Kidney
Volani 2015 Abstract IOC106Volani C, Haschka D, Demetz E, Doerrier C, Gnaiger E, Weiss G (2015) Determination of mitochondrial respiration in peripheral blood mononuclear cells. Mitochondr Physiol Network 20.10.Human
Mouse
Heart
Liver
Blood cells
Lymphocyte
Lindquist 2015 Abstract IOC106Alteraas EK, Lindquist C, Berge RK, Bjorndal B (2015) OXPHOS capacity in mouse liver altered by modified fatty acids that inhibit or stimulate beta-oxidation. Mitochondr Physiol Network 20.10.MouseLiver
Madlala 2015 Abstract MiPschool Cape Town 2015Fructose-induced ROS production: The role of uric acid and transforming growth factor (TGF)-ÎČ1.HumanLiver
Other cell lines
MacDonald 2014 Abstract MiP2014The mitochondrial enzyme 4-hydroxy-2-oxoglutarate aldolase (HOGA) – involvement in the TCA cycle.RatHeart
Nervous system
Liver
Kidney
El-Bacha 2014 Abstract MiP2014Cytotoxicity of grape pomace extract (Vitis vinifera L.) from Brazilian wine industry in human hepatocarcinoma HepG2 cells.HumanLiver
Figueira 2014 Abstract MiP2014Mitochondrial respiration and calcium transport in rat tissues: conversely from skeletal muscle, heart and brain, isolated liver mitochondria exhibit gender dimorphism in respiratory activity.RatHeart
Skeletal muscle
Nervous system
Liver
Houghton 2014 Abstract MiP2014The effect of bioactive phenolics on chronic mitochondrial stress associated with the onset of diabetes.HumanLiver
Sumbalova 2014 Abstract MiP2014Optimization of malate concentration for high-resolution respirometry: mitochondria from rat liver and brain.RatNervous system
Liver
Sobotka 2014 Abstract IOC95Sobotka O (2014) Effect of α-Tocopheryl succinate on Complex II. Mitochondr Physiol Network 19.10RatHeart
Liver
Legkun 2014 Abstract IOC 2014-04 SchroeckenLegkun G, Motovilov K (2014) Investigation on alternative mechanism of electron transport in the respiratory system. Mitochondr Physiol Network 19.02.RatLiver
Slinde 2013 Abstract MiP2013Slinde E, Egelandsdal B, Olsen RE (2013) Respiration of tissue and mitochondria from Atlantic salmon (Salmo salar, L) liver, muscle, heart, brain and blood. Mitochondr Physiol Network 18.08.Other mammals
Fishes
Heart
Liver
Blood cells
Dungel 2013 Abstract MiP2013Dungel P, Perlinger M, Faulhammer B, Weidinger A, Redl H, Kozlov AV (2013) Iron-mediated injury of mitochondria is attenuated by nitrite. Mitochondr Physiol Network 18.08.RatLiver
Kozlov 2013 Abstract MiP2013Kozlov AV, Paier-Pourani J, Weidinger A, Dungel P, Redl H, Duvigneau C (2013) Regulatory role of mitochondrial ROS upon inflammation. Mitochondr Physiol Network 18.08.RatLiver
Staples 2013 Abstract MiP2013Staples JF(2013) Mechanisms of mitochondrial metabolic suppression in hibernation. Mitochondr Physiol Network 18.08.Other mammalsLiver
Irving 2013 Abstract MiP2013Irving BA, Stahl R, Kane CJ, Chernousov M, Argyropoulos G, Carey D (2013) Sex differences in murine mitochondrial oxidative capacity following a 24 week high-fat diet. Mitochondr Physiol Network 18.08.MouseSkeletal muscle
Liver
Fat
Kallijarvi 2013 Abstract IOC75Kallijarvi J (2013) Respiratory chain dysfunction in the Complex III assembly disorder GRACILE. Mitochondr Physiol Network 18.03.Human
Mouse
Liver
Kidney
Fibroblast
Szibor 2013 Abstract MiP2013Szibor M, Heidler J, Gizatullina Z, Salwig I, Dhandapani PK, Wittig I, Rustin P (2013) Expression of Ciona intestinalis alternative oxidase in mouse. Mitochondr Physiol Network 18.08.MouseHeart
Skeletal muscle
Nervous system
Liver
Lung;gill
Garcia-Roves 2013 Abstract MiP2013Garcia-Roves PM, Gonzalez-Franquesa A, Martinez-Navarro L, Fernandez-Ruiz R (2013) Metabolic flexibility before and after lifestyle intervention in a diet-induced type 2 diabetes animal model. Mitochondr Physiol Network 18.08.MouseSkeletal muscle
Nervous system
Liver
Islet cell;pancreas;thymus
Fat
Tretter 2013 Abstract MiP2013Tretter L, Komlódi T, Ádåm-Vizi V (2013) The effects of methylmalonic acid on alpha-ketoglutarate supported oxidation in isolated brain, heart and liver mitochondria. Mitochondr Physiol Network 18.08.Guinea pigHeart
Nervous system
Liver
Galina 2013 Abstract MiP2013Galina A, Messeder DJM, Camacho-Pereira J, Pereira da Silva AP, Rodrigues-Ferreira C (2013) Effects of antitumor alkylating agent 3-bromopyruvate on energy transducing pathways in hepatoma HepG2, liver mitochondria and SERCA: Is there any role for mitochondrial hexokinase activity? Mitochondr Physiol Network 18.08.RatSkeletal muscle
Nervous system
Liver
Other cell lines
Schulte 2013 Abstract MiP2013Chung DJ, Schulte PM, Richards JG (2013) The effect of low-temperature acclimation on mitochondrial function in the common killifish (Fundulus heteroclitus), a top-down elasticity analysis. Mitochondr Physiol Network 18.08.FishesLiver
Brandt 2013 Abstract MiP2013Brandt T, Mourier A, Stewart JB, Larsson NG, KĂŒhlbrandt W (2013) Structure and function of aged mouse mitochondria. Mitochondr Physiol Network 18.08.MouseHeart
Liver
Kidney
Krumschnabel 2013 Abstract MiP2013Krumschnabel G, Eigentler A, Fontana-Ayoub M, Draxl A, Fasching M, Gnaiger E (2013) Tissue homogenates for respiratory OXPHOS analysis in comparative mitochondrial physiology: mouse and trout – heart and liver. Mitochondr Physiol Network 18.08.Mouse
Fishes
Heart
Nervous system
Liver
Quistorff 2013 Abstract MiP2013Quistorff B (2013) With type 2 diabetes mitochondrial dysfunction develops earlier in liver than in skeletal muscle. Mitochondr Physiol Network 18.08.RatSkeletal muscle
Liver
Calzia 2013 Abstract MiP2013Calzia E, Wagner K, Wagner F, Groeger M, Matallo J, McCook O, Wachter U, Vogt J, Radermacher P (2013) Studying mitochondrial effects of sulfide. Does the species matter? Mitochondr Physiol Network 18.08.Pig
Mouse
Liver
Camacho-Pereira 2013 Abstract IOC75Camacho-Pereira J (2013) CD38 as a regulator of mitochondrial function. Mitochondr Physiol Network 18.03.MouseLiver
HEK
Macrophage-derived
Labieniec-Watala 2012 Abstract BioblastLabieniec-Watala M, Siewiera K, Watala C (2012) Seasonal fluctuations affect the physiology of laboratory animals – facts and artifacts from the perspective of heart mitochondrial respiratory response to tested compounds. Mitochondr Physiol Network 17.12.Mouse
Rat
Heart
Liver
Fibroblast
Irving 2012 Abstract IOC72Irving BA (2012) AgRP deficient female mice have elevated body weight and hypothalamic mitochondrial oxidative capacity. Mitochondr Physiol Network 17.13.Mouse
Rat
Skeletal muscle
Nervous system
Liver
Fat
Acuna-Castroviejo 2012 Abstract BioblastAcuna-Castroviejo D (2012) Melatonin and the quality of life: the melatonin-mitochondrion connection. Mitochondr Physiol Network 17.12.Mouse
Rat
Heart
Skeletal muscle
Nervous system
Liver
Tronstad 2012 Abstract BioblastNikolaisen J, Nilsson LIH, Hagland HR, Koopman WJ, Tronstad KJ (2012) Mitochondrial morphology and biogenesis in cellular stress. Mitochondr Physiol Network 17.12.Human
Rat
Liver
Endothelial;epithelial;mesothelial cell
Blood cells
Cervinkova 2012 Abstract BioblastCervinkova Z, Stankova P, Cervinka M, Kucera O, Drahota Z (2012) Evaluation of mitochondrial functions – an important tool for experimental hepatology. Mitochondr Physiol Network 17.12.RatLiver
Mark 2012 Abstract BioblastMark FC, Strobel A, Poertner HO (2012) Ocean warming and acidification – when fish mitochondria turn sour. Mitochondr Physiol Network 17.12.FishesHeart
Liver
Hoppel 2012 Abstract BioblastHoppel CL (2012) Mitochondrial functional testing – muscle biopsy, isolated mitochondria and others. Mitochondr Physiol Network 17.12.HumanSkeletal muscle
Liver
Eigentler 2012 Abstract BioblastEigentler A, Draxl A, Fontana-Ayoub M, Gnaiger E (2012) The PBI-Shredder - an auxiliary HRR-tool for the preparation of tissue homogenates for diagnosis of mitochondrial respiratory function. Mitochondr Physiol Network 17.12.MouseHeart
Nervous system
Liver
Kiss 2012 Abstract BioblastKiss G, Konrad C, Doczi J, Starkov AA, Kawamata H, Manfredi G, Zhang SF, Gibson GE, Beal MF, Adam-Vizi V, Chinopoulos C (2012) The negative impact of alpha-ketoglutarate dehydrogenase complex deficiency on matrix substrate-level phosphorylation. Mitochondr Physiol Network 17.12.MouseNervous system
Liver
Chu SRS 2011Chu MJJ, Hickey AJ, Tagoloa S, Zhang L, Dare A, MacDonald J, Yeong M, Bartlett A, Phillips A (2011) Hepatic mitochondrial dysfunction during cold ischaemia. SRS Adelaide 2011.MouseLiver
Gupte MiP2010Gupte AA, Liu JZ, Ren Y, Minze LJ, Wiles JR, Collins AR, Lyon CJ, Hsueh WA (2010) Age- and diet-related mitochondrial dysfunction in a novel mouse model of metabolic syndrome is rescued by treatment with a PPARÎł agonistMouseLiver
ElBacha 2010 Abstract IOC60El-Bacha T, Abud M, Galina A, Da Poian AT (2010) Bioenergetics of liver mitochondria from mice infected with Dengue virus. MiPNet15.10.MouseLiver

Comparative: tissues and cells

»Tissues, cell types and cell lines