- high-resolution terminology - matching measurements at high-resolution
NS e-input
Description
CI&II e-input is electron input though Complexes CI plus CII simultaneously into the Q-junction corresponding to TCA cycle function in vivo, with convergent electron flow through the ETS. In mt-preparations, CI&II e-input requires addition not only of CI substrate (pyruvate+malate or glutamate+malate), but of succinate simultaneously, since metabolite depletion in the absence of succinate prevents a significant stimulation of CII.
Reference: Gnaiger 2012 MitoPathways, Gnaiger 2009 Int J Biochem Cell Biol
MitoPedia methods:
Respirometry
Labels:
Enzyme: Complex I, Complex II; Succinate Dehydrogenase"Complex II; Succinate Dehydrogenase" is not in the list (Adenine nucleotide translocase, Complex I, Complex II;succinate dehydrogenase, Complex III, Complex IV;cytochrome c oxidase, Complex V;ATP synthase, Inner mt-membrane transporter, Marker enzyme, Supercomplex, TCA cycle and matrix dehydrogenases, ...) of allowed values for the "Enzyme" property.
