Difference between revisions of "NS e-input"
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|description='''NS e-input''' (CI<small>&</small>II e-input) is electron input from a combination of [[N]] and [[S]] substrates through Complexes [[CI]] and [[CII]] simultaneously into the [[Q-junction]] corresponding to [[TCA cycle]] function ''in vivo'', with [[convergent electron flow]] through the [[ETS]]. In [[Mitochondrial preparations|mt-preparations]], NS e-input requires addition not only of N (CI-linked) substrate (pyruvate&malate or glutamate&malate), but of S (succinate) simultaneously, since [[metabolite depletion]] in the absence of succinate prevents a significant stimulation of S-linked respiration. For more details, see: [[Additive effect of convergent NS-electron flow]]. | |description='''NS e-input''' (CI<small>&</small>II e-input) is electron input from a combination of [[N]] and [[S]] substrates through Complexes [[CI]] and [[CII]] simultaneously into the [[Q-junction]] corresponding to [[TCA cycle]] function ''in vivo'', with [[convergent electron flow]] through the [[ETS]]. In [[Mitochondrial preparations|mt-preparations]], NS e-input requires addition not only of N (CI-linked) substrate (pyruvate&malate or glutamate&malate), but of S (succinate) simultaneously, since [[metabolite depletion]] in the absence of succinate prevents a significant stimulation of S-linked respiration. For more details, see: [[Additive effect of convergent NS-electron flow]]. | ||
|info=[[Gnaiger 2014 MitoPathways]], [[Gnaiger 2009 Int J Biochem Cell Biol]] | |info=[[Gnaiger 2014 MitoPathways]], [[Gnaiger 2009 Int J Biochem Cell Biol]] | ||
|type=Transport | |||
}} | }} | ||
{{MitoPedia concepts|type=Transport | {{MitoPedia concepts|type=Transport | ||
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{{MitoPedia methods | {{MitoPedia methods | ||
|mitopedia method=Respirometry | |mitopedia method=Respirometry | ||
|type=Transport | |||
}} | }} | ||
{{MitoPedia O2k and high-resolution respirometry|type=Transport | {{MitoPedia O2k and high-resolution respirometry | ||
|mitopedia O2k and high-resolution respirometry=SUIT state | |||
|type=Transport | |||
}} | }} | ||
{{MitoPedia topics | {{MitoPedia topics|type=Transport | ||
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}} | }} | ||
Revision as of 21:42, 20 March 2016
- high-resolution terminology - matching measurements at high-resolution
NS e-input
Description
NS e-input (CI&II e-input) is electron input from a combination of N and S substrates through Complexes CI and CII simultaneously into the Q-junction corresponding to TCA cycle function in vivo, with convergent electron flow through the ETS. In mt-preparations, NS e-input requires addition not only of N (CI-linked) substrate (pyruvate&malate or glutamate&malate), but of S (succinate) simultaneously, since metabolite depletion in the absence of succinate prevents a significant stimulation of S-linked respiration. For more details, see: Additive effect of convergent NS-electron flow.
Abbreviation: NS, CI&II
Reference: Gnaiger 2014 MitoPathways, Gnaiger 2009 Int J Biochem Cell Biol
MitoPedia methods: Respirometry
MitoPedia O2k and high-resolution respirometry: "SUIT state" is not in the list (O2k hardware, DatLab, Oroboros QM, O2k-Open Support, O2k-Respirometry, O2k-FluoRespirometry) of allowed values for the "MitoPedia O2k and high-resolution respirometry" property.
SUIT state"SUIT state" is not in the list (O2k hardware, DatLab, Oroboros QM, O2k-Open Support, O2k-Respirometry, O2k-FluoRespirometry) of allowed values for the "MitoPedia O2k and high-resolution respirometry" property.
