Difference between revisions of "NADH"

Latest revision as of 12:21, 12 December 2023

high-resolution terminology - matching measurements at high-resolution

NADH

Description

NAD⁺ and NADH: see Nicotinamide adenine dinucleotide.

Abbreviation: NADH

NADH-Module

For information on the NADH-Module, see: NADH-Module

Manual: MiPNet26.12_NextGen-O2k:_NADH-Module

MitoPedia topics: Substrate and metabolite

@@ Line 1: / Line 1: @@
 {{MitoPedia
-|abbr=n, NADH
+|abbr=NADH
-|description='''Nicotinadeninedinucleotide (NADH)''' is not permeable through the inner mt-membrane.  The NADH pool integrates the activity of the [[TCA cycle]] and various matrix dehydrogenases upstream of [[CI]], and thus forms a junction or funnel of electron transfer to CI.  Cytosolic NADH is effectively made available for mitochondrial respiration through the [[malate-aspartate shuttle]] or [[Glycerophosphate_dehydrogenase_complex|glycerophosphate dehydrogenase]].
+|description='''NAD<sup>+</sup>''' and '''NADH''': see [[Nicotinamide adenine dinucleotide]].
-|type=Substrate ETS
-}}
-{{MitoPedia methods|type=Substrate ETS
 }}
+== NADH-Module ==
+:::: For information on the NADH-Module, see: [[NADH-Module]]
+:::: Manual: [[MiPNet26.12_NextGen-O2k:_NADH-Module]]
+{{MitoPedia concepts}}
+{{MitoPedia methods}}
+{{MitoPedia O2k and high-resolution respirometry}}
 {{MitoPedia topics
 |mitopedia topic=Substrate and metabolite
-|type=Substrate ETS
 }}
-{{Labeling
-|enzymes=Complex I
-}}
-== Application in [[HRR]]  ==
-'''n: Nicotinadeninedinucleotide, NADH''' (β-Nicotinamide adenine dinucleotide, reduced potassium salt, C<sub>21</sub>H<sub>27</sub>N<sub>7</sub>O<sub>14</sub>P<sub>2</sub>K<sub>2</sub>);  Sigma A 4505, 100 mg, store at -20 °C (old Sigma recommendation : 4-8°); FW = 742.61, for important considerations concerning storage of NADH (powder and solutions) and preparation of solutions see the product information from Sigma: [https://www.sigmaaldrich.com/content/dam/sigma-aldrich/docs/Sigma/Product_Information_Sheet/2/n4505pis.pdf]. The same precautions are recommended by Sigma for the sodium salt.