- high-resolution terminology - matching measurements at high-resolution
N-junction
Description
The N-junction is a junction for convergent electron flow in the electron transfer system (ETS) from type N substrates through the mt-NADH pool to Complex I (CI), and further transfer through the Q-junction to Complex III (CIII). Representative type N substrates are pyruvate, glutamate and malate. The corresponding dehydrogenases (PDH, GDH, MDH) generate NADH, the substrate of Complex I (CI). The concept of the N-junction and F-junction provides a basis for defining categories of SUIT protocols based on pathway control states.
Reference: Gnaiger 2014 MitoPathways
MitoPedia concepts:
MiP concept,
SUIT concept
MitoPedia methods:
Respirometry
Contributed by Gnaiger E 2016-02-12; edited 2016-08-28.
