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Difference between revisions of "N-junction"

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{{MitoPedia
{{MitoPedia
|description=[[File:SUIT-Catg N.jpg|right|300px|N-junction]]
|description=[[File:SUIT-Catg N.jpg|right|300px|N-junction]]
The '''N-junction''' is a junction for [[convergent electron flow]] in the [[electron transfer system]] (ETS) from [[N]]-type substrates through the mt-[[NADH]] pool to [[Complex I]] (CI), and further transfer through the [[Q-junction]] to [[Complex III]] (CIII). Representative [[Substrate types |type N substrates]] are pyruvate, glutamate and malate. The corresponding dehydrogenases (PDH, GDH, MDH) generate NADH, the substrate of [[Complex I]] (CI). The concept of the N-junction and [[F-junction]] provides a basis for defining [[categories of SUIT protocols]] based on [[substrate types]].
The '''N-junction''' is a junction for [[convergent electron flow]] in the [[electron transfer system]] (ETS) from [[NADH-linked substrate state |type N substrates]] through the mt-[[NADH]] pool to [[Complex I]] (CI), and further transfer through the [[Q-junction]] to [[Complex III]] (CIII). Representative [[Substrate types |type N substrates]] are pyruvate, glutamate and malate. The corresponding dehydrogenases (PDH, GDH, MDH) generate NADH, the substrate of [[Complex I]] (CI). The concept of the N-junction and [[F-junction]] provides a basis for defining [[categories of SUIT protocols]] based on [[substrate types]].
|info=[[Gnaiger 2014 MitoPathways]]
|info=[[Gnaiger 2014 MitoPathways]]
}}
}}

Revision as of 18:00, 27 March 2016


high-resolution terminology - matching measurements at high-resolution


N-junction

Description

N-junction

The N-junction is a junction for convergent electron flow in the electron transfer system (ETS) from type N substrates through the mt-NADH pool to Complex I (CI), and further transfer through the Q-junction to Complex III (CIII). Representative type N substrates are pyruvate, glutamate and malate. The corresponding dehydrogenases (PDH, GDH, MDH) generate NADH, the substrate of Complex I (CI). The concept of the N-junction and F-junction provides a basis for defining categories of SUIT protocols based on substrate types.


Reference: Gnaiger 2014 MitoPathways


MitoPedia methods: Respirometry 


MitoPedia O2k and high-resolution respirometry: "SUIT protocol" is not in the list (O2k hardware, DatLab, Oroboros QM, O2k-Open Support, O2k-Respirometry, O2k-FluoRespirometry) of allowed values for the "MitoPedia O2k and high-resolution respirometry" property. SUIT protocol"SUIT protocol" is not in the list (O2k hardware, DatLab, Oroboros QM, O2k-Open Support, O2k-Respirometry, O2k-FluoRespirometry) of allowed values for the "MitoPedia O2k and high-resolution respirometry" property. 

Contributed by Gnaiger E 2016-02-12