Difference between revisions of "LEAK state without adenylates"
| Line 3: | Line 3: | ||
|description=In the '''LEAK state without adenylates''', ''L''<sub>N</sub> (N for no adenylates), mitochondrial respiration is measured after addition of substrates, which decreases slowly to the [[LEAK state]] after oxidation of endogenous substrates with no [[adenylate|adenylates]]. | |description=In the '''LEAK state without adenylates''', ''L''<sub>N</sub> (N for no adenylates), mitochondrial respiration is measured after addition of substrates, which decreases slowly to the [[LEAK state]] after oxidation of endogenous substrates with no [[adenylate|adenylates]]. | ||
|info=[[MiPNet12.15]]; [[List of respiratory states]] | |info=[[MiPNet12.15]]; [[List of respiratory states]] | ||
|type=Respiration | |||
}} | |||
{{MitoPedia topics | |||
|mitopedia topic=Respiratory state | |||
|type=Respiration | |type=Respiration | ||
}} | }} | ||
Revision as of 13:51, 9 March 2011
- high-resolution terminology - matching measurements at high-resolution
LEAK state without adenylates
Description
In the LEAK state without adenylates, LN (N for no adenylates), mitochondrial respiration is measured after addition of substrates, which decreases slowly to the LEAK state after oxidation of endogenous substrates with no adenylates.
Abbreviation: LN
Reference: MiPNet12.15; List of respiratory states
MitoPedia topics: "Respiratory state" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property.
Respiratory state"Respiratory state" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property.
Labels:
Regulation: Respiratory state"Respiratory state" is not in the list (Aerobic glycolysis, ADP, ATP, ATP production, AMP, Calcium, Coupling efficiency;uncoupling, Cyt c, Flux control, Inhibitor, ...) of allowed values for the "Respiration and regulation" property., Respiration; OXPHOS; ETS Capacity"Respiration; OXPHOS; ETS Capacity" is not in the list (Aerobic glycolysis, ADP, ATP, ATP production, AMP, Calcium, Coupling efficiency;uncoupling, Cyt c, Flux control, Inhibitor, ...) of allowed values for the "Respiration and regulation" property., Coupling; Membrane Potential"Coupling; Membrane Potential" is not in the list (Aerobic glycolysis, ADP, ATP, ATP production, AMP, Calcium, Coupling efficiency;uncoupling, Cyt c, Flux control, Inhibitor, ...) of allowed values for the "Respiration and regulation" property., ATP; ADP; AMP; PCr"ATP; ADP; AMP; PCr" is not in the list (Aerobic glycolysis, ADP, ATP, ATP production, AMP, Calcium, Coupling efficiency;uncoupling, Cyt c, Flux control, Inhibitor, ...) of allowed values for the "Respiration and regulation" property.
HRR: Theory
State 2
State 2 was re-defined as functionally the same as State 4 (Nicholls and Ferguson 2002). State 2 (Chance and Williams 1955, 1956), however, is substrate-limited residual oxygen consumption at high ADP (ROXD), whereas LN and LT (State 4) are LEAK states in the absence of adenylates (LN: no ADP, no ATP) or presence of ATP (LT).
