Difference between revisions of "Ebanks 2022 Abstract Bioblast"
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{{Abstract | {{Abstract | ||
|title=<u>Ebanks Brad</u>, Wang Y, Katyal G, Sargent C, Ingram TL, Bowman A, Moisoi N, Chakrabarti L (2022) Exercise alters mitochondrial physiology and has age-specific impacts on the fitness and lifespan of ''D. melanogaster''. Bioblast 2022: BEC Inaugural Conference. | |title=[[File:Ebanks.jpg|left|100px|Brad Ebanks]]<u>Ebanks Brad</u>, Wang Y, Katyal G, Sargent C, Ingram TL, Bowman A, Moisoi N, Chakrabarti L (2022) Exercise alters mitochondrial physiology and has age-specific impacts on the fitness and lifespan of ''D. melanogaster''. Bioblast 2022: BEC Inaugural Conference. | ||
|info=[https://wiki.oroboros.at/index.php/Bioblast_2022#Submitted_abstracts Bioblast 2022: BEC Inaugural Conference] | |info=[https://wiki.oroboros.at/index.php/Bioblast_2022#Submitted_abstracts Bioblast 2022: BEC Inaugural Conference] | ||
|authors=Ebanks Brad, Wang Y, Katyal G, Sargent C, Ingram TL, Bowman A, Moisoi Nicoleta, Chakrabarti Lisa | |authors=Ebanks Brad, Wang Y, Katyal G, Sargent C, Ingram TL, Bowman A, Moisoi Nicoleta, Chakrabarti Lisa |
Revision as of 10:56, 7 June 2022
Ebanks Brad, Wang Y, Katyal G, Sargent C, Ingram TL, Bowman A, Moisoi N, Chakrabarti L (2022) Exercise alters mitochondrial physiology and has age-specific impacts on the fitness and lifespan of D. melanogaster. Bioblast 2022: BEC Inaugural Conference. |
Link: Bioblast 2022: BEC Inaugural Conference
Ebanks Brad, Wang Y, Katyal G, Sargent C, Ingram TL, Bowman A, Moisoi Nicoleta, Chakrabarti Lisa (2022)
Event: Bioblast 2022
Biological ageing is one of the biggest risk factors for a range of diseases, including cancers, neurodegenerative disease, and heart disease. Mitochondrial dysfunction is associated with both ageing and diseases of ageing. As exercise is increasingly being viewed as a potential anti-ageing therapy, we sought to assess the impact of exercise on the fitness and lifespan of D. melanogaster[1]. In addition, we assessed the exercise-induced changes to mitochondrial physiology through high-resolution respirometry and label-free mass spectrometry. Exercise in late life extends the lifespan of male and female D. melanogaster compared with those exercised throughout their entire lifetime. Exercise also increases Complex-II-linked respiration and upregulates the expression of proteins from the electron transfer Complexes I, III, IV.
- Ebanks B, Wang Y, Katyal G, Sargent C, Ingram TL, Bowman A, Moisoi N, Chakrabarti L (2021) Exercising D. melanogaster modulates the mitochondrial proteome and physiology. The effect on lifespan depends upon age and sex. https://doi.org/10.3390/ijms222111606
β’ Keywords: Drosophila; ageing; exercise; lifespan; mitochondria; proteomics; respirometry
Affiliations
- University of Nottingham, UK - [email protected]
List of abbreviations, terms and definitions - MitoPedia
Labels: MiParea: Exercise physiology;nutrition;life style Pathology: Aging;senescence
Organism: Drosophila
HRR: Oxygraph-2k