Difference between revisions of "Ebanks 2022 Abstract Bioblast"
Tindle Lisa (talk | contribs) (Created page with "link=Bioblast_2022 {{Abstract |title=<u>Ebanks Brad</u> (2022) Exercise alters mitochondrial physiology and has age-specific impacts on the fi...") Β |
Tindle Lisa (talk | contribs) |
||
Line 1: | Line 1: | ||
{{Abstract | {{Abstract | ||
|title=<u>Ebanks Brad</u> (2022) Exercise alters mitochondrial physiology and has age-specific impacts on the fitness and lifespan of ''D. melanogaster''. Bioblast 2022: BEC Inaugural Conference. | |title=<u>Ebanks Brad</u> (2022) Exercise alters mitochondrial physiology and has age-specific impacts on the fitness and lifespan of ''D. melanogaster''. Bioblast 2022: BEC Inaugural Conference. | ||
Line 6: | Line 5: | ||
|year=2022 | |year=2022 | ||
|event=[[Bioblast 2022]] | |event=[[Bioblast 2022]] | ||
|abstract= | |abstract=Biological ageing is one of the biggest risk factors for a range of diseases, including cancers, neurodegenerative disease, and heart disease. Mitochondrial dysfunction is associated with both ageing and diseases of ageing. As exercise is increasingly being viewed as a potential anti-ageing therapy, we sought to assess the impact of exercise on the fitness and lifespan of ''D. melanogaster''[1]. In addition, we assessed the exercise-induced changes to mitochondrial physiology through high-resolution respirometry and label-free mass spectrometry. Exercise in late life extends the lifespan of male and female ''D. melanogaster'' compared with those exercised throughout their entire lifetime. Exercise also increases Complex-II-linked respiration and upregulates the expression of proteins from the electron transfer Complexes I, III, IV. | ||
|keywords=Drosophila; ageing; exercise; lifespan; mitochondria; proteomics; respirometry | |keywords=Drosophila; ageing; exercise; lifespan; mitochondria; proteomics; respirometry | ||
| | }} | ||
{{Labeling | |||
|area=Exercise physiology;nutrition;life style | |||
|diseases=Aging;senescence | |||
|organism=Drosophila | |||
|instruments=Oxygraph-2k | |||
|articletype=Abstract | |||
}} | |||
[[File:Bioblast2022 banner.jpg|link=Bioblast_2022]] | |||
== Affiliations == | == Affiliations == | ||
::::University of Nottingham, UK - [email protected] | ::::University of Nottingham, UK - [email protected] | ||
Line 20: | Line 24: | ||
== List of abbreviations, terms and definitions - MitoPedia == | == List of abbreviations, terms and definitions - MitoPedia == | ||
{{Template:List of abbreviations, terms and definitions - MitoPedia}} | {{Template:List of abbreviations, terms and definitions - MitoPedia}} | ||
Revision as of 13:31, 31 May 2022
Ebanks Brad (2022) Exercise alters mitochondrial physiology and has age-specific impacts on the fitness and lifespan of D. melanogaster. Bioblast 2022: BEC Inaugural Conference. |
Link: Bioblast 2022: BEC Inaugural Conference
Ebanks Brad (2022)
Event: Bioblast 2022
Biological ageing is one of the biggest risk factors for a range of diseases, including cancers, neurodegenerative disease, and heart disease. Mitochondrial dysfunction is associated with both ageing and diseases of ageing. As exercise is increasingly being viewed as a potential anti-ageing therapy, we sought to assess the impact of exercise on the fitness and lifespan of D. melanogaster[1]. In addition, we assessed the exercise-induced changes to mitochondrial physiology through high-resolution respirometry and label-free mass spectrometry. Exercise in late life extends the lifespan of male and female D. melanogaster compared with those exercised throughout their entire lifetime. Exercise also increases Complex-II-linked respiration and upregulates the expression of proteins from the electron transfer Complexes I, III, IV.
β’ Keywords: Drosophila; ageing; exercise; lifespan; mitochondria; proteomics; respirometry
Labels: MiParea: Exercise physiology;nutrition;life style Pathology: Aging;senescence
Organism: Drosophila
HRR: Oxygraph-2k
Affiliations
- University of Nottingham, UK - [email protected]
References
- Ebanks, B. et al (2021) Exercising D. melanogaster modulates the mitochondrial proteome and physiology. The effect on lifespan depends upon age and sex. Int. J. Mol. Sci. 22: 11606. doi:10.3390/ijms222111606