Revision as of 19:25, 21 April 2014

high-resolution terminology - matching measurements at high-resolution

E-L coupling efficiency

Description

The biochemical coupling efficiency is expressed as the E-L coupling control factor, Δj_E-L=(E-L)/E, which is 0.0 at zero coupling (L=E; LEAK=ETS capacity) and 1.0 at the limit of a fully coupled system (L=0). Compare with the thermodynamic or ergodynamic efficiency of coupling between ATP production (DT phosphorylation) and oxygen consumption. > MiPNet article

Abbreviation: Δj_E-L

Reference: Flux control factor

MitoPedia methods: Respirometry

MitoPedia topics: "Respiratory control ratio" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property. Respiratory control ratio"Respiratory control ratio" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property.

Gnaiger E (2014) Biochemical coupling efficiency: from 0 to <1. Mitochondr Physiol Network 2014-04-18.

OROBOROS (2014) Mitochondr Physiol Network

Abstract: Zooming in on biochemical coupling efficiency.

• O2k-Network Lab: AT Innsbruck Gnaiger E

Labels:

Regulation: Coupling efficiency;uncoupling Coupling state: LEAK, ETS"ETS" is not in the list (LEAK, ROUTINE, OXPHOS, ET) of allowed values for the "Coupling states" property.

HRR: Theory

Biochemical coupling efficiency: from 0 to <1

Related terms in MitoPedia

Efficiency

Efficiency - Ergodynamic efficiency ^[1],^[2]

Coupling

Is respiration uncoupled - noncoupled - dyscoupled? ^[3]

Coupling control factors

Coupling control ratios

Relevant respiratory states

ETS capacity - compare OXPHOS capacity ^[4]
ETS-competent substrate state
LEAK respiration

Basics

References

↑ Gnaiger E (1993) Nonequilibrium thermodynamics of energy transformations. Pure Appl Chem 65: 1983-2002. »Open Access
↑ Gnaiger E (1993) Efficiency and power strategies under hypoxia. Is low efficiency at high glycolytic ATP production a paradox? In: Surviving Hypoxia: Mechanisms of Control and Adaptation. Hochachka PW, Lutz PL, Sick T, Rosenthal M, Van den Thillart G (eds) CRC Press, Boca Raton, Ann Arbor, London, Tokyo: 77-109. »Bioblast Access
↑ Gnaiger E. Is respiration uncoupled - noncoupled - dyscoupled? Mitochondr Physiol Network. »Uncoupler
↑ Gnaiger E (2012) Mitochondrial pathways and respiratory control. An introduction to OXPHOS analysis. 3rd ed. Mitochondr Physiol Network 17.18. OROBOROS MiPNet Publications, Innsbruck: 64 pp. »Open Access

[1] Gnaiger E (1993) Nonequilibrium thermodynamics of energy transformations. Pure Appl Chem 65: 1983-2002. »Open Access

[2] Gnaiger E (1993) Efficiency and power strategies under hypoxia. Is low efficiency at high glycolytic ATP production a paradox? In: Surviving Hypoxia: Mechanisms of Control and Adaptation. Hochachka PW, Lutz PL, Sick T, Rosenthal M, Van den Thillart G (eds) CRC Press, Boca Raton, Ann Arbor, London, Tokyo: 77-109. »Bioblast Access

[3] Gnaiger E. Is respiration uncoupled - noncoupled - dyscoupled? Mitochondr Physiol Network. »Uncoupler

[4] Gnaiger E (2012) Mitochondrial pathways and respiratory control. An introduction to OXPHOS analysis. 3rd ed. Mitochondr Physiol Network 17.18. OROBOROS MiPNet Publications, Innsbruck: 64 pp. »Open Access

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@@ Line 31: / Line 31: @@
 === Efficiency ===
-* [[Efficiency]] - [[Ergodynamic efficiency]] <ref>Gnaiger E (1993) Nonequilibrium thermodynamics of energy transformations. Pure Appl Chem 65: 1983-2002. >> [[Gnaiger 1993 Pure Appl Chem | '''Open Access''']]</ref>,<ref>Gnaiger E (1993) Efficiency and power strategies under hypoxia. Is low efficiency at high glycolytic ATP production a paradox? In: Surviving Hypoxia: Mechanisms of Control and Adaptation. Hochachka PW, Lutz PL, Sick T, Rosenthal M, Van den Thillart G (eds) CRC Press, Boca Raton, Ann Arbor, London, Tokyo: 77-109. >> [[Gnaiger 1993 Hypoxia | '''Bioblast Access]]</ref>
+* [[Efficiency]] - [[Ergodynamic efficiency]] <ref> Gnaiger E (1993) Nonequilibrium thermodynamics of energy transformations. Pure Appl Chem 65: 1983-2002. [[Gnaiger 1993 Pure Appl Chem |»Open Access]]</ref>,<ref>Gnaiger E (1993) Efficiency and power strategies under hypoxia. Is low efficiency at high glycolytic ATP production a paradox? In: Surviving Hypoxia: Mechanisms of Control and Adaptation. Hochachka PW, Lutz PL, Sick T, Rosenthal M, Van den Thillart G (eds) CRC Press, Boca Raton, Ann Arbor, London, Tokyo: 77-109. [[Gnaiger 1993 Hypoxia |»Bioblast Access]]</ref>
 === Coupling ===
-* Is respiration uncoupled - noncoupled - dyscoupled? <ref>Gnaiger E. Is respiration uncoupled - noncoupled - dyscoupled? Mitochondr Physiol Network. >> [[Uncoupler]]</ref>
+* Is respiration uncoupled - noncoupled - dyscoupled? <ref>Gnaiger E. Is respiration uncoupled - noncoupled - dyscoupled? Mitochondr Physiol Network. »[[Uncoupler]]</ref>
 === Coupling control factors ===
@@ Line 50: / Line 50: @@
 === Relevant respiratory states ===
-* [[ETS capacity]] - compare [[OXPHOS capacity]] <ref>Gnaiger E (2012) Mitochondrial Pathways and Respiratory Control. An Introduction to OXPHOS Analysis. 3rd ed. Mitochondr Physiol Network 17.18. OROBOROS MiPNet Publications, Innsbruck: 64 pp. >> [[Gnaiger 2012 MitoPathways | '''Open Access''']]</ref>
+* [[ETS capacity]] - compare [[OXPHOS capacity]] <ref> Gnaiger E (2012) Mitochondrial pathways and respiratory control. An introduction to OXPHOS analysis. 3rd ed. Mitochondr Physiol Network 17.18. OROBOROS MiPNet Publications, Innsbruck: 64 pp. [[Gnaiger 2012 MitoPathways |»Open Access]]</ref>
 * [[ETS-competent substrate state]]
 * [[LEAK respiration]]

Difference between revisions of "E-L coupling efficiency"